Group Therapy for Depression in Ukrainian Civilians During War

This clinical trial examines the effectiveness of Empowerment Group Therapy, a culturally adapted CBT-based program, for Ukrainian adults experiencing depression, anxiety, or stress during wartime. Conducted by Charité University in collaboration with Ukrainian partners, the study aims to provide mental health support to civilians affected by the ongoing conflict.

The intervention consists of 10 weekly therapy sessions delivered either in-person or online, accommodating participants' safety needs during unstable war conditions. Each group of 10-14 participants will receive:

• Mindfulness and breathing exercises
• Psychoeducation about mental health
• Behavioral activation techniques
• A culturally adapted workbook for homework exercises

Researchers will measure both practical aspects (like attendance rates) and clinical outcomes at multiple time points. The study particularly focuses on:

• Feasibility of delivering mental health care during active conflict
• Changes in depression/anxiety symptoms using validated scales
• Improvements in quality of life and resilience
• Reduction in PTSD and somatic symptoms

This research is critically important as it addresses the urgent mental health needs of war-affected populations. The study design acknowledges real-world challenges by allowing flexible participation (online or in-person) and using culturally sensitive materials. If successful, this model could be replicated in other conflict zones.

Mental health interventions during humanitarian crises face unique challenges including safety concerns, disrupted infrastructure, and cultural barriers. This study represents an innovative approach by combining evidence-based therapy with practical adaptations for wartime conditions. The focus on group therapy makes it potentially scalable for populations with limited access to individual treatment.

For participants, the program offers not just symptom relief but also practical coping strategies and connection with others experiencing similar challenges. The inclusion of follow-up assessments will help determine whether benefits persist after treatment ends. This research could significantly advance our understanding of effective mental health interventions in active conflict zones.