Visual Stimulus and Eye Movement

Visual Motor Coordination in Man

This study is designed to understand how we see visual patterns and how these patterns lead to eye movements.

Normal volunteers participating in this study face a screen on which spots or patterns of light are projected. They are asked to respond to the patterns by voice, eye movements or hand movements. Eye and lid movements are recorded in one of the following ways:

1. Electro-oculogram < small disc electrodes taped to the skin near each eye measure the eye movements as the eyes change position.
2. Infrared detector < an infrared beam is reflected off the eye and picked up by detectors that record the eye movements.
3. Contact lens ring < a smooth plastic ring is placed on the white of the eye surrounding the cornea and eye position is measured using a magnetic coil.

Study sessions last less than four hours.

Study Overview

• Status: Completed
• Conditions: Healthy

Detailed Description

The purpose of this protocol is to study the physiology of the visuo-motor system in normal humans. This will be accomplished by recording eye movements and other responses (such as reaction time to bar press or verbal responses) to differing stimuli. The stimuli will be primarily visual but may include auditory or tactile stimuli.

• Study Type: Observational
• Enrollment: 225

Contacts and Locations

Study Locations

• United States
  • Maryland
    • Bethesda, Maryland, United States, 20892
      • National Institutes of Health Clinical Center, 9000 Rockville Pike

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 59 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

• INCLUSION CRITERIA:

Normal adult volunteers age 18 and over are included.

Only normal volunteers are studied under this protocol. Normal volunteers are recruited from the NIH volunteer office and the NIH web page. Women and minorities are actively recruited.

Study Plan

How is the study designed?

Collaborators and Investigators

• Sponsor: National Eye Institute (NEI)

Publications and helpful links

General Publications

• Miles FA. The neural processing of 3-D visual information: evidence from eye movements. Eur J Neurosci. 1998 Mar;10(3):811-22. doi: 10.1046/j.1460-9568.1998.00112.x.
• Busettini C, Masson GS, Miles FA. Radial optic flow induces vergence eye movements with ultra-short latencies. Nature. 1997 Dec 4;390(6659):512-5. doi: 10.1038/37359.
• Masson GS, Busettini C, Miles FA. Vergence eye movements in response to binocular disparity without depth perception. Nature. 1997 Sep 18;389(6648):283-6. doi: 10.1038/38496.

Study record dates

Study Major Dates

• Study Start: August 26, 1980
• Study Completion: August 6, 2008

Study Registration Dates

• First Submitted: November 3, 1999
• First Submitted That Met QC Criteria: November 3, 1999
• First Posted (Estimate): November 4, 1999

Study Record Updates

• Last Update Posted (Actual): July 2, 2017
• Last Update Submitted That Met QC Criteria: June 30, 2017
• Last Verified: August 6, 2008

More Information

Terms related to this study

• Keywords: Healthy Volunteer; Vision; Perception; Eye Movement
• Other Study ID Numbers: 800093; 80-EI-0093