- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00013819
Exposure, Dose, Body Burden and Health Effects of Lead
April 13, 2015 updated by: National Institute of Environmental Health Sciences (NIEHS)
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system.
A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea.
Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone.
Subjects are tested three times each over three years.
Several genetic factors are also being assessed for the role they play in the health effects of lead.
These genes are known to differ among individuals.
We are interested to know whether different forms of the same genes can modify the effect lead has on health.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment
944
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
17 years to 70 years (Child, Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Lead workers in South Korea in one of 26 specific lead-using facilities.
Population controls in South Korea.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
February 1, 1997
Primary Completion (Actual)
February 1, 2001
Study Completion (Actual)
February 1, 2001
Study Registration Dates
First Submitted
March 29, 2001
First Submitted That Met QC Criteria
March 29, 2001
First Posted (Estimate)
March 30, 2001
Study Record Updates
Last Update Posted (Estimate)
April 14, 2015
Last Update Submitted That Met QC Criteria
April 13, 2015
Last Verified
April 1, 2015
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 7198-CP-001
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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