- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00179036
Biomagnetic Signals of Intestinal Ischemia II (SQUID)
April 5, 2017 updated by: Alan Bradshaw, Vanderbilt University Medical Center
The lack of blood flow to the small intestine causes mesenteric ischemia.
Using a Superconducting QUantum Interference Device (SQUID) which measures the magnetic field of the small intestine, we are hoping to identify abnormalities without surgical intervention.
Study Overview
Status
Completed
Conditions
Detailed Description
The electrical activity of the small intestine may contain important information that will help us diagnose gastrointestinal diseases.
The major impediment to reducing mortality of mesenteric ischemia is the lack of a noninvasive diagnostic test that identifies the syndrome before extensive necrosis occurs.
Mesenteric ischemia is caused by the lack of blood flow to the intestine.
The Superconducting QUantum Interference Device (SQUID) measures the magnetic field of the intestinal smooth muscle.
By comparing normal smooth muscle and that of patients with mesenteric ischemia, the investigators hope to identify abnormal disease states without surgery.
Study Type
Observational
Enrollment (Actual)
17
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Tennessee
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Nashville, Tennessee, United States, 37232
- Vanderbilt University Medical Center
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
primary care clinic
Description
Inclusion Criteria:
- Normal subjects and those with diagnosed mesenteric ischemia
Exclusion Criteria:
- Subjects who report a tendency toward claustrophobia
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
Good blood flow
Group without any ischemia to the small intestine
|
Poor blood flow
Group with partial ischemia to the small intestine
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
To observe a difference in the magnetic activity between the normal and diseased smooth muscle of the small intestine
Time Frame: 2010
|
2010
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Create mathematical and computer models of electrical activity of smooth muscle
Time Frame: 2010
|
2010
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: William O. Richards, MD, Vanderbilt University Medical Center
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
January 1, 2000
Primary Completion (Actual)
December 1, 2015
Study Completion (Actual)
December 1, 2015
Study Registration Dates
First Submitted
September 13, 2005
First Submitted That Met QC Criteria
September 13, 2005
First Posted (Estimate)
September 15, 2005
Study Record Updates
Last Update Posted (Actual)
April 7, 2017
Last Update Submitted That Met QC Criteria
April 5, 2017
Last Verified
April 1, 2017
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 060426
- R01DK058197 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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