- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00223483
Identification and Analysis of Immunomodulatory Molecules in Patients With Hematologic Disorders and Healthy Volunteers
July 14, 2021 updated by: The University of Texas Health Science Center at San Antonio
Identification and Analysis of Immunomodulatory Molecules From Leukocytes in Patients With Hematologic Disorders and Healthy Volunteers
This research study goal is to analyze the plasma and the cells that make up part of the immune system.
We want to learn how the plasma and cells work.
These may influence why one person will develop an infection and another will not, or why one person develops severe symptoms of a disease while others remain without symptoms.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
This research study goal is to analyze the plasma and the cells that make up part of the immune system.
These cells, called white cells or leukocytes, are present in blood.
We want to learn how these cells work to prevent infection and how they respond after an infection occurs.
We also want to study certain molecules present on the plasma, on or in these cells, and the genetic material that allows these molecules to be made.
These molecules may influence why one person will develop an infection and another will not, or why one person develops severe symptoms of a disease while others remain without symptoms.
This study may increase our understanding of a variety of diseases including infections such as HIV, allergic diseases such as asthma, joint diseases such as rheumatoid arthritis, certain cancers, and the rejection process that sometimes occurs after transplantation of an organ.
Study Type
Observational
Enrollment (Actual)
512
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Texas
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San Antonio, Texas, United States, 78229
- The University of Texas Health Science Center at San Antonio
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San Antonio, Texas, United States, 78229
- Department of Veterans Affairs, South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital Division
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Primary care clinic and community samples
Description
Inclusion Criteria:
- Must be able to give blood
- Must be able to give informed consent
- Signed, written informed consent
Exclusion Criteria:
- Individuals with a history severe anemia, inadequate venous access, severe blood or coagulation disorders.
- Pregnant women are excluded because it is a unique immunotolerant state and will alter the profile of immunomodulatory molecules.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Repository collection of plasma and serum for future analysis.
Time Frame: 12 years
|
12 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Study Director: Cesar O Freytes, MD, The University of Texas Health Science Center at San Antonio
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
March 1, 2005
Primary Completion (Actual)
December 11, 2020
Study Completion (Actual)
July 14, 2021
Study Registration Dates
First Submitted
September 13, 2005
First Submitted That Met QC Criteria
September 13, 2005
First Posted (Estimate)
September 22, 2005
Study Record Updates
Last Update Posted (Actual)
July 16, 2021
Last Update Submitted That Met QC Criteria
July 14, 2021
Last Verified
July 1, 2021
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- HSC20040268H
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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