Effect of Cola on Urinary Stone Risk Factors

Effect of Cola on Urinary Stone Risk Factors

Sponsors

Lead sponsor: Emory University

Source Emory University
Brief Summary

Examine the effects of cola on risks of kidney stones

Detailed Description

Prospective crossover study examining the risks of cola on stone risk factors.

Overall Status Completed
Start Date November 2003
Completion Date October 2011
Primary Completion Date October 2011
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
The Plasma and Urine Parameters at the end of each 6-day intervention in Cola and Water Phase
The Plasma and Urine Parameters at the end of 6-day intervention of Cola and water phase
The Plasma Osmolarity at the end of 6-day intervention of cola and water phase
The Plasma and Urine Parameters at the end of 6-day intervention of Cola and water phase
Secondary Outcome
Measure Time Frame
Total Urine Volume at the end of each 6-day intervention in Cola and Water Phase
Urinary pH at the end of each 6-day intervention in Cola and Water Phase
Enrollment 13
Condition
Intervention

Intervention type: Drug

Intervention name: Cola beverage

Description: Subjects will be given 500cc of Cola beverage twice daily to be ingested with breakfast and dinner for six days while on a metabolic diet.There will be a three weeks interval before crossover to the other treatment arm.

Arm group label: Cola beverage

Intervention type: Drug

Intervention name: Deionized water

Description: Subjects will be given 500cc of deionized water to be ingested twice daily with breakfast and dinner for three weeks while on a metabolic diet. There will be a three weeks interval before crossover to the other treatment arm

Arm group label: Deionized water

Eligibility

Criteria:

Inclusion Criteria:

- urolithiasis, healthy volunteer

Exclusion Criteria:

-

Gender: All

Minimum age: 18 Years

Maximum age: N/A

Healthy volunteers: Accepts Healthy Volunteers

Overall Official
Last Name Role Affiliation
Kenneth Ogan, MD Principal Investigator Emory University
Location
facility
Emory University
Location Countries

United States

Verification Date

May 2016

Responsible Party

Responsible party type: Principal Investigator

Investigator affiliation: Emory University

Investigator full name: Kenneth Ogan, MD

Investigator title: Associate Professor

Keywords
Has Expanded Access No
Condition Browse
Number Of Arms 2
Arm Group

Arm group label: Cola beverage

Arm group type: Experimental

Description: Subjects will be given 500cc of Cola twice daily.

Arm group label: Deionized water

Arm group type: Placebo Comparator

Description: Subjects will be given 500cc of deionized water.

Study Design Info

Allocation: Non-Randomized

Intervention model: Crossover Assignment

Primary purpose: Health Services Research

Masking: None (Open Label)

Source: ClinicalTrials.gov