THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation

June 20, 2011 updated by: CardioKine Inc.

The purpose of this study is to determine the safety and efficacy of lixivaptan in the treatment of hyponatremia in patients with congestive heart failure.

Study Overview

Status

Completed

Conditions

Hyponatremia

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

652

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Argentina
- - Buenos Aires, Argentina, 1027
    - Research Site
  - Buenos Aires, Argentina, 1210
    - Research Site
  - Buenos Aires, Argentina, 1437
    - Research Site 1
  - Buenos Aires, Argentina, 1605
    - Research Site 1
  - Buenos Aires, Argentina, 1878
    - Research Site 1
  - Buenos Aires, Argentina, 2900
    - Research Site 1
  - Buenos Aires, Argentina, 8000
    - Research Site 1
  - Buenos Aires, Argentina, B1708KCH
    - Research Site 1
  - Buenos Aires, Argentina, C1426BOR
    - Hospital Militar Central H Gral. 601 "Cirujano Mayor Dr. Cosme Argerich"
  - Buenos Aires, Argentina
    - Hospital de Clinicas "Jose De San Martin"
  - Cerrientes, Argentina
    - Research Site 1
  - Provincia de Buenos Aires, Argentina
    - Research Site 1
  - Provincia de Misiones, Argentina, 3300
    - Research Site 1
  - Provincia de Santa Fe, Argentina
    - Research Site 1
  - Tucuman, Argentina, 4000
    - Research Site 1
- Buenos Aires
  - San Martin, Buenos Aires, Argentina, 1650
    - hospital Interzonal General de Agudos, "Eva Peron" (HIGA)
- Galvan
  - Ciudad Autonomo de Buenos Aires, Galvan, Argentina, CP FWO1431
    - Research Site
- Santa Fe
  - Rosario, Santa Fe, Argentina, CP2000
    - Research Site
Canada
- - Manitoba, Canada, R2H 2A6
    - Research Site 1
  - New Brunswick, Canada, E2K 4P8
    - Research Site 1
  - Quebec, Canada, G1V 4G5
    - Research Site 1
  - Quebec, Canada, J6E 6J2
    - Research Site 1
  - Vancouver, Canada, V6Z 1Y6
    - Research Site 1
- Ontario
  - Kitchener, Ontario, Canada, N2N 2A8
    - Research Site 1
  - Ottawa, Ontario, Canada, K1Y 4W7
    - Research Site 1
  - Scarborough, Ontario, Canada, M1P2T7
    - Research Site 1
  - Toronto, Ontario, Canada, M5G 2N2
    - Research Site 1
- Quebec
  - Montreal, Quebec, Canada, H2W 1T8
    - Research Site 1
  - Montreal, Quebec, Canada, H3A 1A1
    - Research Site 1
  - Sherbrooke, Quebec, Canada, J1H 5N4
    - Research Site 1
  - St. Jerome, Quebec, Canada, J7Z 5T3
    - Research Site 1
Chile
- - Antofagasta, Chile, 1945
    - Research Site 1
  - Concepcion, Chile
    - Research Site 1
  - Orosno, Chile
    - Research Site 1
  - Puerto Montt, Chile
    - Hospital De Puerto Montt
  - Santiago, Chile, 0155
    - Research Site
  - Santiago, Chile, 3204
    - Research Site 1
  - Santiago, Chile
    - Research Site 1
  - Temuco, Chile, 115
    - Research Site
  - Vina del Mar, Chile, 1532
    - Research Site 1
Czech Republic
- - Havlickuv Brod, Czech Republic, 580 22
    - Research Site 1
  - Kladno, Czech Republic, 272 59
    - Research Site 1
  - Kromeriz, Czech Republic, 767 55
    - Research Site 1
  - Liberec, Czech Republic, 460-63
    - Research Site 1
  - Mestec Kralove, Czech Republic, 289 03
    - Research Site 1
  - Ostrava, Czech Republic, 72880
    - Research Site 1
  - Praha, Czech Republic, 150 30
    - Research Site 1
  - Praha, Czech Republic, 180 81
    - Research Site 1
  - Praha 1, Czech Republic
    - Research Site 1
  - Praha 2, Czech Republic, 128 08
    - Research Site 1
  - Pribram, Czech Republic, 261 26
    - Research Site 1
  - Znojmo, Czech Republic, 669 02
    - Research Site 1
Germany
- - Bad Krozingen, Germany, 71989
    - Research Site 1
  - Bad Nauheim, Germany, 61231
    - Research Site 1
  - Bad Segeberg, Germany, 23795
    - Research Site 1
  - Berlin, Germany, 12200
    - Research Site 1
  - Berlin, Germany, 13353
    - Research Site 1
  - Bonn, Germany, 53105
    - Research Site 1
  - Coburg, Germany, 96450
    - Research Site 1
  - Dresden, Germany, 01307
    - Research Site 1
  - Gottingen, Germany, 37075
    - Research Site 1
  - Greifswald, Germany, 17475
    - Research Site 1
  - Hamburg, Germany, 20246
    - Research Site 1
  - Hannover, Germany, 30167
    - Research Site 1
  - Hannover, Germany, 30625
    - Research Site 1
  - Jena, Germany, 07747
    - Research Site 1
  - Karisbad, Germany, 76307
    - Research Site 1
  - Konstanz, Germany, 78464
    - Research Site 1
  - Leipzig, Germany, 04289
    - Research Site 1
  - Regensburg, Germany, 93053
    - Research Site 1
  - Regensburg, Germany, 94053
    - Research Site 1
  - Rostock, Germany, 18057
    - Research Site 1
  - Soest, Germany, 59494
    - Research Site 1
India
- - Bikaner, India, 334001
    - Research Site
  - Coimbatore, India
    - Research Site 1
  - Madhya Pradesh, India
    - Research Site 1
  - Maharashtra, India
    - Research Site 1
  - Maharastra, India
    - Research Site 1
  - Mumbai, India, 400 007
    - Research Site
  - New Delhi, India, 110076
    - Research Site
  - New Delhi, India
    - Sir Ganga Ram Hospital
  - New Delhi, India, 110025
    - Research Site
  - Rajasthan, India
    - Research Site 1
  - Tamul Nadu, India, 600116
    - Sri Ramachandra Medical College of research Institute
- Andhra Pradesh
  - Secunderabad, Andhra Pradesh, India, 500 003
    - Research Site
- Chennai
  - Mogappair, Chennai, India, 600037
    - Research Site
- Gujarat
  - Naranpura, Gujarat, India, 380014
    - Research Site
- Hyderabad
  - Panjagutta, Hyderabad, India, 500082
    - Research Site
- Karnataka
  - Bangalore, Karnataka, India, 560 054
    - Research Site
  - Bangalore, Karnataka, India, 560 034
    - Research Site
  - Bangalore, Karnataka, India, 560052
    - Research Site
- Nashik
  - College Road, Nashik, India, 422 005
    - Research Site
  - Shalimar, Nashik, India, 422 002
    - Shree Saibaba Heart Institute and Research Centre
Israel
- - Be'er-Sheva, Israel, 84101
    - Research Site 1
  - Haifa, Israel, 31048
    - Research Site
  - Haifa, Israel, 31048
    - Research Site 1
  - Holon, Israel, 58100
    - Research Site 1
  - Jerusalem, Israel, 91120
    - Research Site
  - Jerusalem, Israel, 91004
    - Research Site 1
  - Jerusalem, Israel, 91240
    - Research Site 1
  - Petah Tkva, Israel
    - Research Site 1
  - Safed, Israel, 13100
    - Research Site 1
  - Tel Aviv, Israel, 64239
    - Research Site 1
Italy
- - Bologna, Italy, 40138
    - Research Site 1
  - Brescia, Italy, 25123
    - Research Site
  - Cecina, Italy, 57023
    - Research Site 1
  - Cortina, Italy, 52044
    - Research Site 1
  - Genova, Italy, 16132
    - Research Site 1
  - Milano, Italy, 20132
    - Research Site 1
  - Novara, Italy, 28100
    - Research Site 1
  - Parma, Italy, 43100
    - Research Site 1
  - Pavia, Italy, 27100
    - Research Site 1
  - Piacenza, Italy, 29100
    - Research Site 1
  - Ravenna, Italy
    - Research Site 1
  - Roma, Italy, 00161
    - Research Site 1
  - Torino, Italy, 10126
    - Azienda Ospedaliero-Universitaria "San Giovanni Battista di Torino" Struttura Complessa Cardiologia 1
  - Torino, Italy, 10126
    - Research Site 1
Poland
- - Bydgoszcz, Poland, 85-168
    - Research Site 1
  - Gdynia, Poland, 81-519
    - Research Site 1
  - Kielce, Poland, 25-736
    - Research Site
  - Krakow, Poland, 31-121
    - Research Site 1
  - Krakow, Poland, 31-501
    - Research Site 2
  - Krakow, Poland, 31-913
    - Research Site
  - Lubartow, Poland, 21-100
    - Research Site
  - Ostroleka, Poland, 07-410
    - Samodzielny Zespol Publicznych Zakladow Opieki Zdrowotnej
  - Ostrowiec Swietokrzyski, Poland, 27-400
    - Research Site 1
  - Pabianice, Poland, 95-200
    - Research Site
  - Piotrkow Trybunalski, Poland, 97-300
    - Samodzielnl Szpital Wojewodzki
  - Radom, Poland, 26-617
    - Wojewodzki Szpital Specjalistczny w Radomiu, Oddzial Kardiologil
  - Sieradz, Poland, 98-200
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej
  - Starogard Gdanski, Poland
    - Research Site
  - Torun, Poland, 87-100
    - Research Site 1
  - Warszawa, Poland, 04-141
    - Wojskowy Instytut Medyczny
  - Warszawa, Poland, 00-909
    - Research Site 1
  - Warszawa, Poland, 01-211
    - Research Site 1
  - Warszawa, Poland, 02-005
    - Research Site 1
  - Warszawa, Poland, 02-507
    - Research Site 1
  - Warszawa, Poland, 02-637
    - Research Site 1
  - Warszawa, Poland, 04-749
    - Research Site 1
  - Wroclaw, Poland, 50-367
    - Research Site 1
  - Wroclaw, Poland, 51-124
    - Research Site 1
- Nysa
  - Curie 1, Nysa, Poland, 48-300
    - Research Site
Romania
- - Brasov, Romania, 500152
    - Research Site
  - Bucharest, Romania, 014461
    - Research Site 1
  - Bucharest, Romania, 030572
    - Research Site 1
  - Tg Mures, Romania, 540136
    - Research Site 1
  - Timisoara, Romania, 300310
    - Research Site 1
Russian Federation
- - Saint Petersburg, Russian Federation, 191187
    - Research Site 1
- Moscow
  - Lenskaya, Moscow, Russian Federation, 129327
    - Research Site 1
- Russia
  - Moscow, Russia, Russian Federation, 109240
    - Research Site 1
  - Moscow, Russia, Russian Federation, 111020
    - Research Site 1
  - Moscow, Russia, Russian Federation, 115487
    - Research Site 1
  - Moscow, Russia, Russian Federation, 115516
    - Research Site 1
  - Moscow, Russia, Russian Federation, 119192
    - Research Site 1
  - Moscow, Russia, Russian Federation, 119620
    - Research Site 1
  - Moscow, Russia, Russian Federation, 121359
    - Research Site 1
  - Moscow, Russia, Russian Federation, 123423
    - Research Site 1
  - Moscow, Russia, Russian Federation, 125284
    - Research Site 1
  - Moscow, Russia, Russian Federation, 127018
    - Research Site 1
  - Moscow, Russia, Russian Federation, 127473
    - Research Site 1
  - Moscow, Russia, Russian Federation, 129110
    - Research Site
  - Moscow, Russia, Russian Federation, 129301
    - Research Site 1
  - Moscow, Russia, Russian Federation, 129336
    - Research Site 1
  - Moscow, Russia, Russian Federation
    - Research Site 1
  - Saint-Petersburg, Russia, Russian Federation, 192242
    - Research Site 1
  - Saint-Petersburg, Russia, Russian Federation, 194156
    - Research Site 1
  - Saint-Petersburg, Russia, Russian Federation, 196247
    - Research Site 1
  - Saint-Petersburg, Russia, Russian Federation, 197110
    - Research Site 1
  - Saint-Petersburg, Russia, Russian Federation, 199106
    - Research Site 1
- Saint-Petersburg
  - L'va Tolstogo, Saint-Petersburg, Russian Federation, 197022
    - Research Site 1
  - Solidamosty, Saint-Petersburg, Russian Federation, 193312
    - Research Site 1
Slovakia
- - Bratislava, Slovakia, 826 06
    - Research Site 1
  - Nitra, Slovakia, 949 01
    - Research Site 1
  - Trencin, Slovakia, 91171
    - Interna klinika, Fakultna nemocnica Trencin
Spain
- - Barcelona, Spain, 08036
    - Research Site 1
  - Barcelona, Spain, 08003
    - Research Site 1
  - Cordoba, Spain, 14004
    - Research Site 1
  - Madrid, Spain, 28007
    - Research Site 1
  - Malaga, Spain, 29010
    - Hospital Univeritario Virgen de la Victoria Servicio de Cardiologia
  - Malaga, Spain, 29010
    - Research Site 1
  - Santiago de Compostela, Spain, 15706
    - Research Site 1
  - Vigo, Spain, 36200
    - Research Site 1
Switzerland
- - Geneva, Switzerland, 1217
    - Research Site
United States
- Alabama
  - Birmingham, Alabama, United States, 35211
    - Research Site 1
  - Birmingham, Alabama, United States, 35294
    - Research Site 1
  - Mobile, Alabama, United States, 36604
    - Research Site 1
- California
  - Bakersfield, California, United States, 93308
    - Research Site 1
  - Banning, California, United States, 92220
    - Research Site 1
  - Glendale, California, United States, 91204
    - Research Site
  - Glendale, California, United States, 91204
    - Research Site 1
  - Los Angeles, California, United States, 90048
    - Research Site 1
  - Mission Viejo, California, United States, 92691
    - Research Site 1
  - Roseville, California, United States, 95661
    - Research Site 1
  - San Diego, California, United States, 92103
    - Research Site 1
  - San Diego, California, United States, 92161
    - Research Site 1
- Colorado
  - Aurora, Colorado, United States, 80045
    - Research Site 1
- Delaware
  - Newark, Delaware, United States, 19718
    - Research Site 1
- District of Columbia
  - Washington, District of Columbia, United States, 20010
    - Research Site 1
- Florida
  - Bay Pines, Florida, United States, 33744
    - Research Site 1
  - Ft. Lauderdale, Florida, United States, 33316
    - Research Site 1
  - Gainesville, Florida, United States, 32610
    - Research Site 1
  - Jacksonville, Florida, United States, 32209
    - Research Site 1
  - Jacksonville, Florida, United States, 32216
    - Research Site 1
  - Jacksonville, Florida, United States, 32224
    - Research Site 1
  - Lakeland, Florida, United States, 33805
    - Research Site 1
  - Miami, Florida, United States, 33136
    - Research Site 1
  - Port Charlotte, Florida, United States, 33952
    - Research Site 1
  - Tampa, Florida, United States, 33606
    - Research Site 1
  - Tampa, Florida, United States, 33613
    - Research Site 1
- Georgia
  - Atlanta, Georgia, United States, 30322
    - Research Site 1
- Illinois
  - Bannockburn, Illinois, United States, 60015
    - Research Site 1
  - Chicago, Illinois, United States, 60612
    - Research Site 1
  - Maywood, Illinois, United States, 60153
    - Research Site 1
  - Normal, Illinois, United States, 61761
    - Research Site 1
  - North Chicago, Illinois, United States
    - Research Site 1
  - Oak Lawn, Illinois, United States, 60453
    - Research Site 1
  - Peoria, Illinois, United States, 61606
    - Research Site 1
  - Peoria, Illinois, United States, 61614
    - Research Site 1
- Indiana
  - Munster, Indiana, United States, 46321
    - Research Site 1
- Iowa
  - Iowa City, Iowa, United States, 522442
    - University of Iowa Hospitals and Clinics
  - Iowa City, Iowa, United States, 52245
    - Research Site 1
- Kentucky
  - Louisville, Kentucky, United States, 40202
    - Research Site 1
  - Louisville, Kentucky, United States, 40207
    - Research Site 1
- Louisiana
  - New Orleans, Louisiana, United States, 70112
    - Research Site 1
  - Slidell, Louisiana, United States, 70458
    - Research Site 1
- Maryland
  - Baltimore, Maryland, United States, 21229
    - Research Site 1
- Massachusetts
  - Boston, Massachusetts, United States, 02118
    - Research Site 1
  - Burlington, Massachusetts, United States, 01805
    - Research Site 1
- Michigan
  - Detroit, Michigan, United States, 48201
    - Research Site
  - Detroit, Michigan, United States, 48202
    - Research Site 1
  - Petoskey, Michigan, United States, 49770
    - Northern Michigan Hospital
  - Petoskey, Michigan, United States, 49770
    - Research Site 1
  - Traverse City, Michigan, United States, 49684
    - Research Site 1
- Minnesota
  - Duluth, Minnesota, United States, 55805
    - Research Site 1
- Missouri
  - St. Louis, Missouri, United States, 63104
    - Research Site 1
  - St. Louis, Missouri, United States, 63110
    - Research Site 1
- Nebraska
  - Lincoln, Nebraska, United States, 68506
    - Research Site 1
- New Hampshire
  - Concord, New Hampshire, United States, 03301
    - Research Site 1
- New Jersey
  - Hackensack, New Jersey, United States, 07601
    - Research Site 1
  - Livingston, New Jersey, United States, 07039
    - Siant Barnabas Medical Center
  - Morristown, New Jersey, United States, 07982
    - Research Site 1
  - Newark, New Jersey, United States, 07112
    - Research Site 1
  - Orange, New Jersey, United States, 07052
    - Research Site 1
  - Paramus, New Jersey, United States, 07652
    - Research Site 1
- New York
  - Bronx, New York, United States, 10461
    - Research Site 1
  - Jamaica, New York, United States, 11418
    - Research Site 1
  - New York, New York, United States, 10029
    - Research Site
  - Northport, New York, United States, 11768
    - Research Site 1
  - Stony Brook, New York, United States, 11794
    - Research Site 1
  - Valhalla, New York, United States, 10595
    - Research Site 1
- North Carolina
  - Winston-Salem, North Carolina, United States, 27157
    - Research Site 1
- Ohio
  - Cincinnati, Ohio, United States, 45267
    - Research Site 1
  - Columbus, Ohio, United States, 43205
    - Research Site 1
  - Fairfield, Ohio, United States, 45014
    - Research Site
  - Fairfield, Ohio, United States, 45014
    - Research Site 1
  - Middletown, Ohio, United States, 45042
    - Research Site 1
  - Toledo, Ohio, United States, 43614
    - Research Site 1
- Oklahoma
  - Oklahoma City, Oklahoma, United States, 73112
    - Research Site 1
  - Oklahoma City, Oklahoma, United States, 73120
    - Research Site 2
  - Tulsa, Oklahoma, United States, 74133
    - Research Site 1
- Oregon
  - Springfield, Oregon, United States, 97477
    - Research Site 1
- Pennsylvania
  - Beaver, Pennsylvania, United States, 15009
    - Research Site 1
  - Camp Hill, Pennsylvania, United States, 17011
    - Research Site 1
  - Danville, Pennsylvania, United States, 17822
    - Research Site 1
  - Pittsburg, Pennsylvania, United States, 15212
    - Research Site 1
  - Sayre, Pennsylvania, United States, 18840
    - Research Site1
  - Sellersville, Pennsylvania, United States, 18960
    - Research Site 1
- Tennessee
  - Chattanooga, Tennessee, United States, 37403
    - Research Site 1
  - Germantown, Tennessee, United States, 38138
    - Research Site 1
  - Nashville, Tennessee, United States, 37208
    - Research Site 1
- Texas
  - Amarillo, Texas, United States, 79106
    - Research Site 1
  - Dallas, Texas, United States, 75230
    - Research Site 1
  - Dallas, Texas, United States, 75231
    - Research Site 1
  - Galveston, Texas, United States, 77555
    - Research Site 1
  - Houston, Texas, United States, 77030
    - Research Site 1
  - Houston, Texas, United States, 77074
    - Research Site 1
  - Lubbock, Texas, United States, 79410
    - Research Site 1
  - Temple, Texas, United States, 76508
    - Research Site 1
  - Tyler, Texas, United States, 75701
    - Research Site 1
- Virginia
  - Chesapeake, Virginia, United States, 23320
    - Research Site 1
  - Richmond, Virginia, United States, 232225
    - Research Site 2
  - Richmond, Virginia, United States, 23249
    - Research Site 1
- Washington
  - Seattle, Washington, United States, 98195
    - Research Site 1
- Wisconsin
  - Beloit, Wisconsin, United States, 53511
    - Research Site 1
  - Madison, Wisconsin, United States, 53792
    - Research Site 1

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Description

Inclusion Criteria:

Male and female patients 18 years of age or older with hyponatremia and hospitalized for congestive heart failure.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: TREATMENT
Allocation: RANDOMIZED
Interventional Model: PARALLEL
Masking: TRIPLE

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
PLACEBO_COMPARATOR: Placebo	Drug: Placebo Oral Capsule
EXPERIMENTAL: Active Lixivaptan	Drug: lixivaptan Oral Capsule

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
To determine whether lixivaptan can effectively and safely produce an increase in serum sodium from Baseline in heart failure subjects with hyponatremia and volume overload. Effects on body weight and other clinical measures will be evaluated. Time Frame: 60 days	60 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

CardioKine Inc.

Collaborators

Biogen

Cardiokine Biopharma, LLC

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2007

Primary Completion (ACTUAL)

June 1, 2010

Study Registration Dates

First Submitted

December 19, 2007

First Submitted That Met QC Criteria

December 19, 2007

First Posted (ESTIMATE)

December 21, 2007

Study Record Updates

Last Update Posted (ESTIMATE)

June 28, 2011

Last Update Submitted That Met QC Criteria

June 20, 2011

Last Verified

November 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

CK-LX3401

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation

Study Overview

Status

Conditions

Intervention / Treatment

Study Type

Enrollment (Actual)

Phase

Contacts and Locations

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Genders Eligible for Study

Description

Study Plan

How is the study designed?

Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Time Frame

Collaborators and Investigators

Sponsor

Collaborators

Study record dates

Study Major Dates

Study Start

Primary Completion (ACTUAL)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (ESTIMATE)

Study Record Updates

Last Update Posted (ESTIMATE)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

Clinical Trials on Hyponatremia

Clinical Trials on Placebo

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Drug Interventions

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Conditions

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Drug Interventions

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