- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00721383
Telephone Resources and Assistance for Caregivers (TRAC) (TRAC)
December 30, 2014 updated by: Carol J Farran, DNSc, RN, FAAN, Rush University Medical Center
Clinical Trial to Enhance Caregiver Physical Activity
The purpose of this randomized clinical trial is to test a 12-month multi-component health promotion intervention with home-based family caregivers of persons with Alzheimer's Disease and other related dementias.
Specific aims are to: 1) Test the primary hypothesis: The Enhancing Physical Activity treatment intervention will be more effective in increasing caregiver lifestyle physical activity than the Standard Care Intervention; 2) Test secondary hypotheses: The Enhancing Physical Activity treatment intervention will be more effective than the Standard Care Intervention in improving the following caregiver secondary outcomes: mental health, physical health and physical function; and 3) Evaluate the process of implementing a lifestyle physical activity intervention with family caregivers.
The Standard Care Intervention focuses on well-established care-related education and support needs.
The Enhancing Physical Activity treatment intervention focuses on two areas: increasing lifestyle physical activity and addressing well-established care-related concerns that are likely to interfere with increasing physical activity.
A total of 190 middle-age to older community-based primary caregivers of persons with Alzheimer's disease or other related dementias who report some to moderate strain with caregiving activities will be randomly assigned to either the Enhancing Physical Activity or Standard Care Intervention.
Data will be collected at baseline, 3, 6, 9, 12 and 18 months and include self-report and direct observational methods.
Data will be analyzed by using repeated measures models using the generalized estimating equation approach.
Family caregivers are a stressed population who experience changes in their mental and physical health.
However, effect sizes have been minimal for interventions designed to only affect caregiver mental health.
No study known to us, has tested the added value of physical activity adoption in conjunction with more traditional caregiver support and skill building.
Study findings will enable us to evaluate the behavioral , physical, and health-related quality of life effects achieved by the combined intervention; and will add knowledge about the most effective ways of intervening with family caregivers and other chronically stressed middle-age and older adult populations.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
211
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
California
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Stanford, California, United States, 94305
- Stanford University School of Medicine
-
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Illinois
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Chicago, Illinois, United States, 60612
- Rush University Medical Center
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
40 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
Care recipient:
- Diagnosis of probable AD or related dementia (using NINCDS/ADA criteria)
- Reside in the community
- Receive assistance from a primary caregiver
Caregiver:
- Are a spouse or other close family member of the person with AD/dementia
- Age ≥ 40 years
- English-speaking
- Live with the care recipient (or close as in 5-10 miles)
- Provide ≥ 10 hours of care per week
- Caregiver for at least 6 months
- Are physically inactive, defined as accumulating ≤ 60 minutes of regular PA on a weekly basis for the past 6 months
- Reporting some to moderate levels of strain
- Are cognitively intact
- Have no major debilitating health problems that would prevent intervention participation
- Must have a telephone
- Willing to increase levels of physical activity
- Agree to assignment of treatment condition
Exclusion Criteria:
Care receiver:
- Other dementias such as stroke or Parkinson's
- Terminal illness with life expectancy of less than six months
- Bedfast or confined to a bed or chair at least 22 hours a day for at least 3 of the previous 7 days
- ≥ 3 acute or medical or psychiatric hospitalizations in last year
Caregiver:
- Are involved in another caregiver clinical trial
- Have a terminal illness with life expectancy of less than 6 months
- Receiving active treatment for cancer
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Treatment
Physical activity and caregiver skill-building
|
Physical activity and caregiver skill-building
Other Names:
|
Active Comparator: Control
caregiver skill-building
|
Caregiver skill-building
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
self-reported physical activity
Time Frame: 18 months
|
18 months
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
caregiving burden
Time Frame: 18 months
|
18 months
|
caregiver positive well-being
Time Frame: 18 months
|
18 months
|
self-reported physical health
Time Frame: 18 months
|
18 months
|
physical function
Time Frame: 18 months
|
18 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Carol J Farran, PhD, Rush University Medical Center
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 2007
Primary Completion (Actual)
February 1, 2013
Study Completion (Actual)
February 1, 2013
Study Registration Dates
First Submitted
July 22, 2008
First Submitted That Met QC Criteria
July 23, 2008
First Posted (Estimate)
July 24, 2008
Study Record Updates
Last Update Posted (Estimate)
December 31, 2014
Last Update Submitted That Met QC Criteria
December 30, 2014
Last Verified
December 1, 2014
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 04092307
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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Clinical Trials on Enhancing Physical Activity Intervention
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Jamie JacksonNational Heart, Lung, and Blood Institute (NHLBI)CompletedPhysical Activity | Cardiovascular Disease OtherUnited States
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Brown UniversityNational Cancer Institute (NCI)Not yet recruiting
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Jamie JacksonCompletedPhysical Activity | Cardiovascular Disease OtherUnited States
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