Epstein-Barr Detection in Oral Cancer

June 24, 2015 updated by: UPECLIN HC FM Botucatu Unesp

Epstein-Barr Detection in Squamous Cell Carcinoma and Healthy Oral Mucosa

The aim of this study is to analyze oral squamous cell carcinoma and healthy oral mucosa for the possible presence of Epstein-Barr virus (EBV).

Study Overview

Status

Completed

Conditions

Detailed Description

Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

Study Type

Observational

Enrollment (Actual)

60

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Brazil
    • São Paulo
      • Araçatuba, São Paulo, Brazil, 16025-050
        • Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

40 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

oral care clinic, community sample

Description

Inclusion Criteria:

  • patients of Oral Cancer Centre - UNESP/Araçatuba - SP
  • with oral squamous cell carcinoma

Exclusion Criteria:

  • without oral squamous cell carcinoma

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
oral cancer
patients with oral squamous cell carcinoma
control group
healthy patients without any oral pathology

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
presence of EBV
Time Frame: 1 hour
Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.
1 hour

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

UPECLIN HC FM Botucatu Unesp

Investigators

  • Principal Investigator: Glauco Issamu I Miyahara, Professor, Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP
  • Study Chair: Lívia T Arêde, student, Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2008

Primary Completion (Actual)

April 1, 2008

Study Completion (Actual)

June 1, 2015

Study Registration Dates

First Submitted

December 22, 2009

First Submitted That Met QC Criteria

December 22, 2009

First Posted (Estimate)

December 24, 2009

Study Record Updates

Last Update Posted (Estimate)

June 25, 2015

Last Update Submitted That Met QC Criteria

June 24, 2015

Last Verified

June 1, 2015

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • upeclin/FOA-Unesp-03

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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