SPECT/CT in the Diagnosis of Dementia

SPECT/CT in the Diagnosis of Dementia


Lead Sponsor: Kuopio University Hospital

Collaborator: University of Eastern Finland

Source Kuopio University Hospital
Brief Summary

Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.

Overall Status Completed
Start Date September 2006
Completion Date January 2010
Primary Completion Date January 2010
Study Type Observational
Primary Outcome
Measure Time Frame
Final diagnosis 4 years
Enrollment 82

Sampling Method: Probability Sample


Inclusion Criteria (one of these):

- healthy control

- mild cognitive impairment (recruited from a population based data)

- clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion Criteria:

- unable to be scanned with SPECT/CT

Gender: All

Minimum Age: N/A

Maximum Age: N/A

Healthy Volunteers: Accepts Healthy Volunteers

Facility: Kuopio University Hospital
Location Countries


Verification Date

April 2010

Responsible Party

Name Title: Esko Vanninen / Professor

Organization: Kuopio University Hospital

Has Expanded Access No
Condition Browse
Study Design Info

Observational Model: Case Control

Time Perspective: Prospective

Source: ClinicalTrials.gov