French National Observatory of Aortic Syndromes (ONSAA)

The study examined the clinical characteristics and conditions of care for patients with acute aortic syndrome (AAS) that will identify patients at risk for increased morbidity and mortality and provide a basis for the eventual achievement of specific studies on the optimal therapeutic management according to different risk profiles. The aim of the Observatory is to provide a photograph "size" of practices in France at present, both in the larger centers than in smaller and optimize diagnostic and therapeutic currently available by the activation pathways of rational management.

Study Overview

• Status: Completed
• Conditions: Acute Aortic Syndrome

• Study Type: Observational
• Enrollment (Actual): 280

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Patients admitted to cardiology, radiology or surgery for a clinical picture suggestive of acute aortic syndrome whose diagnosis was subsequently confirmed in due course of hospitalization by further investigations.

Description

Inclusion Criteria:

• Male or female age (e) over 18 years old
• Patients with a AAS duly authenticated by further tests
• Patients who consented to participate in the study

Exclusion Criteria:

• Refusal of consent for study participation and ancillary studies
• AAS occurring in the aftermath of a traumatic thoracic
• Diagnosis AAS aside in favor of an alternative diagnosis

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Acute Aortic Syndrome; Patients admitted to cardiology, radiology or surgery for a clinical picture suggestive of acute aortic syndrome whose diagnosis was subsequently confirmed in due course of hospitalization by further investigations.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Etiology of AAS	Measure the respective contribution of each of the etiologies of AAS (aortic dissection type A aortic dissection type B aortic wall hematoma, penetrating atherosclerotic ulcer, aneurysm of the thoracic aorta complicated).	1 day

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Clinical picture	Identify and define the specific clinical picture of each of these new entities recently dismembered as part of AAS. Indeed, if the clinical presentation of classic aortic dissection A and B is well known, that of other entities, individualized recently, remains poorly described.	1 day
Diagnostic tests	Evaluate the performance and the respective roles of the various diagnostic tests including recent acquisitions little or no invasive; Trans thoracic ultrasound, ultrasound and trans esophageal chest scan.	1 day

Collaborators and Investigators

• Sponsor: French Cardiology Society
• Investigators: Principal Investigator: Elbaz Meyer, Assistance Publique - Hôpitaux de Paris

Study record dates

Study Major Dates

• Study Start: August 1, 2008
• Primary Completion (Actual): December 1, 2010
• Study Completion (Actual): December 1, 2010

Study Registration Dates

• First Submitted: December 13, 2010
• First Submitted That Met QC Criteria: December 13, 2010
• First Posted (Estimate): December 14, 2010

Study Record Updates

• Last Update Posted (Actual): August 7, 2019
• Last Update Submitted That Met QC Criteria: August 6, 2019
• Last Verified: August 1, 2019

More Information

Terms related to this study

• Keywords: Acute aortic syndrome
• Additional Relevant MeSH Terms: Pathologic Processes; Disease; Syndrome
• Other Study ID Numbers: 07387