Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS) (LENAS)

Seasonality of Stress, Diet, and Physical Activity in Mid-Life Women

The purpose of this study is to develop a better understanding of factors affecting American's energy balance related behaviors - in this case, food intake and activity. In the present study we will describe the relative contributions of individual psychology and physiology (including metabolism, mood, and sleep habits) and external (season, stressors) contributions to changes in adiposity over a year in free-living individuals.

This study will illuminate season's role in changes in energy balance related behaviors and body weight and composition. Ultimately, this information will be used to identify factors affecting food consumption and individual activity during seasonal periods to help to segment interventions for obesity prevention in mid-life women.

Study Overview

• Status: Completed
• Conditions: Obesity; Physical Activity; Stress; Feeding Behavior

Detailed Description

This is a longitudinal, observational study of mid-life women spanning one year.There will be frequent monitoring of food consumption, individual activity and individual- level factors thought to influence food consumption and activity such as dietary restraint, subjective stress, sleep quality and duration, and physiological stress as measured by allostatic load.

Specific aims:

1. To identify seasonal changes in %BF of mid-life women.

   Participant's percentage of body fat will fluctuate, and will be highest at the end of the winter season and lowest at the end of the summer season.

2. To describe predictors of seasonal changes in %BF.

There will be no intervention other than frequent monitoring of food consumption, individual activity and individual- level factors thought to influence food consumption and activity such as dietary restraint, subjective stress, sleep quality and duration, and physiological stress as measured by allostatic load. The volunteers will be asked to complete a 7-day activity and energy expenditure monitoring period (along with body composition assessment, questionnaires regarding individual factors thought to affect food consumption and activity, blood draw and urine collection to measure allostatic load) in each of the four seasons over a 12-month period; between monitoring periods they will come to the GFHNRC for measurement of weight, skin carotenoids for assessment of fruit and vegetable intake, and to provide a morning urine sample monthly (8 times), and receive emails reminding them to log on to a secure server and complete a 24-hr recall 3 times a month (36 times during the year).

The ASA-24 will be administered to assess nutritional intake; Actigraph GT3X+, Actitrainer, and QStarz GPS logger will be used to assess physical activity. Physiological stress will be assessed using the allostatic load index.

• Study Type: Observational
• Enrollment (Actual): 52

Contacts and Locations

Study Locations

• United States
  • North Dakota
    • Grand Forks, North Dakota, United States, 58201
      • Grand Forks Human Nutrition Research Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years to 60 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

• Sampling Method: Non-Probability Sample

Study Population

Middle-aged females

Description

Inclusion Criteria:

• Ambulatory women aged 40-60 years
• Weight stable (±10 lbs) for at least 6 months prior to the start of the study
• Body mass index (BMI) between 18-35 kg/m2
• Access to high-speed internet
• Willing to comply with study requirements

Exclusion Criteria:

• BMI >35 or < 18
• Current smoker or tobacco or nicotine use
• Male sex
• Age <40.0 or >60 years
• Health conditions (cardiovascular, pulmonary, orthopedic, asthma) that would limit participation in physical activity
• Medications that would influence appetite, weight gain or weight loss.
• Intentional changes in diet or large increases in physical activity for the purpose of weight loss during the study. Typical weight maintenance behaviors are not an exclusion criterion.
• Pregnant, lactating, or planning pregnancy.
• Travel plans that do not permit full participation.
• Inability to walk without assistance. The capability to walk upright is fundamental because accelerometry measures the duration and intensity of horizontal physical activities.
• Inability to give consent.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Group 1 (2012-2013); Monitoring of Dietary Intake, Physical Activity and Stress
Group 2 (2013-2014); Monitoring of Dietary Intake, Physical Activity and Stress

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in body fat	Body fat location and amount will be assess by dual-energy X-ray absorptiometry	Season 1, season 2, season 3, season 4

Collaborators and Investigators

• Sponsor: USDA Grand Forks Human Nutrition Research Center
• Investigators: Principal Investigator: James Roemmich, PhD, USDA-ARS-GFHNRC

Publications and helpful links

General Publications

• Jahns L, Johnson LK, Conrad Z, Bukowski M, Raatz SK, Jilcott Pitts S, Wang Y, Ermakov IV, Gellermann W. Concurrent validity of skin carotenoid status as a concentration biomarker of vegetable and fruit intake compared to multiple 24-h recalls and plasma carotenoid concentrations across one year: a cohort study. Nutr J. 2019 Nov 21;18(1):78. doi: 10.1186/s12937-019-0500-0.

Study record dates

Study Major Dates

• Study Start (Actual): June 1, 2012
• Primary Completion (Actual): August 1, 2014
• Study Completion (Actual): August 1, 2014

Study Registration Dates

• First Submitted: August 23, 2012
• First Submitted That Met QC Criteria: August 23, 2012
• First Posted (Estimate): August 28, 2012

Study Record Updates

• Last Update Posted (Actual): May 20, 2020
• Last Update Submitted That Met QC Criteria: May 18, 2020
• Last Verified: May 1, 2020

More Information

Terms related to this study

• Keywords: Humans; Longitudinal Studies; Female; Middle Aged; Time Factors; Body Weight/physiology*; Diet*/statistics & numerical data; Diet*/trends; Exercise/physiology*; Obesity/epidemiology*; Seasons*
• Additional Relevant MeSH Terms: Overnutrition; Nutrition Disorders; Overweight; Body Weight; Obesity
• Other Study ID Numbers: GFHNRC018

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO