Transmission of Mother-Infant Stress Communication (MIBLS)

October 17, 2018 updated by: University of Massachusetts, Boston

Transmission of Discrimination-Related Stress Reactivity and Reduction From Mother to Infant

The central aim of this study is to assess mother-infant communication via behavioral, physiological, and affective indices under conditions where distal stressors may not be directly detectable by the infant.

Study Overview

Status

Completed

Conditions

Detailed Description

This investigation examines a distal maternal stressor on the quality of interaction in mother-infant dyadic communication. Assessments include behavioral, physiological, and affective indices under conditions where distal stressors may not be directly detectable by the infant. The present research examines mother-infant interactions to test the hypothesis of whether maternal stress may be transduced to their infants via multiple pathways. The secondary aim is to explore effective emotion regulation strategies for the mother as potential buffers to stress and additionally reducing early life stress effects on the infant's regulatory development.

While the emotion regulation literature posits that reappraisal may be associated with decreased in physiological and psychological stress, this type of regulation strategy may be ineffective when interfacing with discrimination. The regulation strategy needs to be titrated to the stressor in order to be effective. These findings will have notable social, clinical, and psychological significance,

Study Type

Observational

Enrollment (Actual)

56

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Massachusetts
      • Boston, Massachusetts, United States, 02125
        • University of Mass. Boston
      • Boston, Massachusetts, United States, 02125
        • University of Massachusetts, Boston, Child Development Unit

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

16 years to 38 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Female

Sampling Method

Probability Sample

Study Population

Community sample of women (ages 18-40) with infants ages 4-9 months

Description

Inclusion Criteria:

  • Healthy volunteers

Exclusion Criteria:

  • No presence of heart murmur or wear a pacemaker
  • No medication for hypertensive or cardiovascular disease
  • Not using beta blockers

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Salivary Cortisol
Time Frame: One lab appointment for approximately 80 minutes.
Salivary cortisol is a measure that indicates hypothalamus-pituitary-adrenal axis activity. The study obtains 4 assessments with 20 minutes between each assessment. Participants chew on a cotton role for 2-minutes which is placed in a cortisol salivette tube (Sarstedt)
One lab appointment for approximately 80 minutes.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Salivary Amylase
Time Frame: One lab appointment for approximately 80 minutes.
Salivary amylase is an indicator of sympathetic nervous system activity. The same salivary salivette is used to later extract the amylase.
One lab appointment for approximately 80 minutes.

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mother-infant observations
Time Frame: One lab appointment for approximately 80 minutes.
At four assessment occasions during the one time visit, the mother and infant are observed for a free 2-minute period. Observations include global affect, and (present or not) vocalizations, infant fussiness, and motor activity.
One lab appointment for approximately 80 minutes.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Kymberlee O'Brien, PhD, Postdoctoral Research Fellow
  • Study Director: Celia L Moore, PhD, Director of DSRC and Horizon Center
  • Study Director: Edward Tronick, PhD, Director Child Development Unit

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2013

Primary Completion (Actual)

July 14, 2016

Study Completion (Actual)

July 14, 2016

Study Registration Dates

First Submitted

December 11, 2013

First Submitted That Met QC Criteria

December 11, 2013

First Posted (Estimate)

December 17, 2013

Study Record Updates

Last Update Posted (Actual)

October 18, 2018

Last Update Submitted That Met QC Criteria

October 17, 2018

Last Verified

October 1, 2018

More Information

Terms related to this study

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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