- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02231996
Chronic Granulomatous Disease Study in China
September 3, 2014 updated by: Shanghai Children's Medical Center
CGD is a rare inherited primary immunodeficiency which is caused by the defect in one of the subunits of NADPH oxidase complex.We tend to collect and analyze Chinese CGD patients who are diagnosed in hospitals affiliated to Shanghai Jiao Tong University School of Medicine, including clinical feature, laboratory data and genetic information.
we aim to find out clinical, distribution, genetic characteristic of CGD in Chinese population, etc., thus further improving the level of diagnosis and treatment for CGD.
Study Overview
Status
Unknown
Conditions
Study Type
Observational
Enrollment (Anticipated)
50
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: jing wu
- Email: wujingecnu@163.com
Study Locations
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Shanghai
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Shanghai, Shanghai, China, 200127
- Shanghai Children's Medical Center
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
1 day to 18 years (Child, Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
CGD patients
Description
Inclusion Criteria:
- x-linked and AR-linked Chronic Granulomatous Disease
- history of life-threatening severe infections
- A functional assay demonstrating abnormal NADPH oxidase function or clinical history consistent with CGD
Exclusion Criteria:
- Presence of other primary immunodeficiency syndromes that do not meet the clinical and laboratory criteria for CGD.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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gene mutation
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
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times of pneumonia
Time Frame: 2 years
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2 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
September 1, 2014
Primary Completion (Anticipated)
August 1, 2016
Study Registration Dates
First Submitted
August 29, 2014
First Submitted That Met QC Criteria
September 1, 2014
First Posted (Estimate)
September 4, 2014
Study Record Updates
Last Update Posted (Estimate)
September 5, 2014
Last Update Submitted That Met QC Criteria
September 3, 2014
Last Verified
September 1, 2014
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- CGD-20140829
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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Hubert Serve, Prof., MDUnknown
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