Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

July 9, 2018 updated by: Yijing He
To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.

Study Overview

Status

Completed

Conditions

Detailed Description

Recovery time of postoperative anesthesia is an important index to reflect patient's postoperative health status. The investigators want to collect patients' clinical dates and their blood samples, then extract DNA from blood samples, acquire every patients' genetic variation information. Finally, acquiring the mathematical model of the influence of clinical factors and genetic factors on the recovery time after operation, predicting the recovery time of anesthesia.

Study Type

Observational

Enrollment (Actual)

1453

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Hunan
      • Changsha, Hunan, China, 410008
        • Xiangya Hospital Central South University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Laparoscopic surgery, orthopedics surgery or open surgery patients in Chinese

Description

Inclusion Criteria:

  1. Aged more than 18 years;
  2. General anesthesia for all patients;
  3. Patients underwent surgery for laparoscopic surgery, orthopedics surgery or open surgery;
  4. Patients were not delivered allogeneic blood in three months;
  5. Having the ability to understand and sign the informed consent.

Exclusion Criteria:

  1. Pregnant or lactating women;
  2. Having an immune deficiency, as a patient with HIV infection;
  3. Patients with infectious diseases, such as syphilis;
  4. Patients delivered allogeneic blood in three months;
  5. Researchers believe that may increasing the risk of subjects or interfering clinical trial;
  6. Don't have the ability to understand or sign the informed consent.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Other
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
patients after general anesthesia
Laparoscopic surgery, orthopedics surgery or open surgery patients after general anesthesia

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Recover time of anesthesia
Time Frame: within 24 hours
within 24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Yijing He

Investigators

  • Principal Investigator: Yijing He, MD,PhD, Xiangya Hospital of Central South University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 1, 2016

Primary Completion (Actual)

October 10, 2017

Study Completion (Actual)

December 31, 2017

Study Registration Dates

First Submitted

June 30, 2016

First Submitted That Met QC Criteria

July 1, 2016

First Posted (Estimate)

July 4, 2016

Study Record Updates

Last Update Posted (Actual)

July 10, 2018

Last Update Submitted That Met QC Criteria

July 9, 2018

Last Verified

July 1, 2018

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 2016 MZ/CSU/PS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

IPD Plan Description

data not entered

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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