Factors Associated With High Mortality of Gastric Adenocarcinoma in Thailand Versus Japan

February 26, 2019 updated by: Rapat Pittayanon, MD, King Chulalongkorn Memorial Hospital

The differences in patient's clinicopathological characteristic between high and low prevalence of gastric cancer region should be further examined to elucidate factors that associate with poor survival rate of patients with gastric cancer. Therefore, this study aimed to evaluate characteristics of patients with gastric adenocarcinoma and factors associated with different outcome in Thailand and Japan to find a clue to improve patients' survival in low prevalence country such as Thailand.

This is a retrospective cohort study. It was conducted at King Chulalongkorn Memorial Hospital, Thailand and Osaka Medical Center for Cancer and Cardiovascular Disease, Japan. Eligible cases were selected by using standardized search protocols: formal computer searches of all patients seen at out-patient clinic and/or hospitalized for gastric cancer between 2010 and 2014.Two physicians, who were informed the definition of each variable, individually reviewed chart of patients.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

700

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Thailand
    • Patum Wan
      • Bangkok, Patum Wan, Thailand, 10330
        • King Chulalongkorn Memorial Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

All patients seen at out-patient clinic and/or hospitalized for gastric cancer between 2010 and 2014 in King Chulalongkorn Memorial Hospital, Thailand and Osaka Medical Center for Cancer and Cardiovascular Disease, Japan.

Description

Inclusion Criteria:

  • all patients seen at out-patient clinic and/or hospitalized for gastric cancer between 2010 and 2014.

Exclusion Criteria:

  • Age < 18 years
  • Incomplete data
  • Miss diagnosis of gastric adenocarcinoma
  • Died from other causes (not related to gastric adenocarcinoma).

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Thailand
Thai patients who diagnosed gastric cancer
Other: Treatment
Observe the treatments of gastric cancer in each group
Japan
Japanese patients who diagnosed gastric cancer
Other: Treatment
Observe the treatments of gastric cancer in each group

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Factors that associated with mortality rate in Thailand compared to Japan
Time Frame: 2010-2014
2010-2014

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

King Chulalongkorn Memorial Hospital

Collaborators

Osaka Medical Center for Cancer and Cardiovascular Diseases

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

December 1, 2016

Primary Completion (ACTUAL)

February 28, 2017

Study Completion (ACTUAL)

August 31, 2017

Study Registration Dates

First Submitted

February 11, 2017

First Submitted That Met QC Criteria

February 16, 2017

First Posted (ACTUAL)

February 23, 2017

Study Record Updates

Last Update Posted (ACTUAL)

February 27, 2019

Last Update Submitted That Met QC Criteria

February 26, 2019

Last Verified

February 1, 2019

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 029/59

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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