Epidemiological Characteristics and Prognosis Factors of Cancer Patients Admitted at French Emergency Departments (EPICANCER)

Patients with cancer or hematological malignancy are susceptible to present acute complications linked to their disease or to their specific treatments (dyspnea, sepsis, coma, hemorrhagic syndrome). Emergency physicians are in first line when these complications arise and have to face with some complex situations in which informations about patient malignancy or prognosis may be lacking. Nowadays, there is very few epidemiological data published concerning how cancer patient use Emergency Departments (EDs) and cancer patient care delivery in the EDs.

Thus, an observational multicenter prospective cross-sectional study is conducted to study the prevalence of cancer patients admitted to French EDs, and to describe the different reasons for cancer patients to seek care in EDs with their prevalence and underscore those linked to cancer or treatment complication

Study Overview

• Status: Completed
• Conditions: Emergencies; Cancer Patients

• Study Type: Observational
• Enrollment (Actual): 1380

Contacts and Locations

Study Locations

• France
  • Paris, France, 75010
    • Hôpital Saint Louis

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients of 18 years or more with active malignancy or in remission for less than 5 years and being attended in one of the 400 French emergency centers participating in the study during 3 consecutive days will be enrolled

Description

Inclusion Criteria:

• adult patients (age >=18 years)
• with active malignancy or a history of cancer in remission within the last 5 years
• being attended in one of the 400 French emergency centers participating in the study during the 3-day study period

Exclusion Criteria:

• opposition to participate

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Reasons for cancer patients to seek care in EDs	1 day

Secondary Outcome Measures

Outcome Measure	Time Frame
cancer location	1 day
hospitalisation rate	1 day
intensive care unit (ICU) admission	7 days
ICU mortality	7 days

Collaborators and Investigators

• Sponsor: Assistance Publique - Hôpitaux de Paris
• Investigators: Principal Investigator: Olivier Peyrony, MD, Assistance Publique - Hôpitaux de Paris

Publications and helpful links

General Publications

• Peyrony O, Fontaine JP, Trabattoni E, Nakad L, Charreyre S, Picaud A, Bosc J, Viglino D, Jacquin L, Laribi S, Pereira L, Thiriez S, Paquet AL, Tanneau A, Azoulay E, Chevret S, Initiatives de Recherche Aux Urgences Iru-Sfmu Research Group. Cancer Patients' Prehospital Emergency Care: Post Hoc Analysis from the French Prospective Multicenter Study EPICANCER. J Clin Med. 2021 Mar 9;10(5):1145. doi: 10.3390/jcm10051145.

Study record dates

Study Major Dates

• Study Start (Actual): February 6, 2018
• Primary Completion (Actual): February 9, 2018
• Study Completion (Actual): October 31, 2019

Study Registration Dates

• First Submitted: December 20, 2017
• First Submitted That Met QC Criteria: January 2, 2018
• First Posted (Actual): January 8, 2018

Study Record Updates

• Last Update Posted (Actual): January 7, 2020
• Last Update Submitted That Met QC Criteria: January 6, 2020
• Last Verified: December 1, 2019

More Information

Terms related to this study

• Keywords: cancer; emergency departments (ED)
• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Emergencies
• Other Study ID Numbers: IRU2017

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No