The Use of Aging Biomarkers in Saliva, Based on DNA Methylation Status in Elovl2 to Predict Biological Age

Clinical Trials on Prediction of Biological Age Using Saliva Samples of Healthy Population, Based on DNA Methylation Status in ELOVL2 Gene

Sponsors

Lead Sponsor: HKGepitherapeutics

Source HKGepitherapeutics
Brief Summary

There is a big change in our understanding of aging in recent years. Recent researches has revealed clock-like patterns of epigenetic change across in humans. The aging involves a timed epigenetic reprogramming. However, this biological clock which ticks in our DNA is affected by our experience, diet, stress, etc. and it could be changed by experience and life style potentially.

The purpose of this study is to develop and test non-invasive biomarkers based on methylation changes in ELOVL2-AS1 gene in saliva samples using a next generation sequencing.

Overall Status Not yet recruiting
Start Date December 1, 2019
Completion Date December 1, 2021
Primary Completion Date July 1, 2020
Study Type Observational
Primary Outcome
Measure Time Frame
The Use of Aging Biomarkers in Saliva, Based on DNA Methylation Status in Elovl2 to Predict Biological Age. 6 months to 1 year
Enrollment 100
Condition
Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- Healthy population

Exclusion Criteria:

- Chronic diseases

Gender: All

Minimum Age: 18 Years

Maximum Age: 100 Years

Healthy Volunteers: Accepts Healthy Volunteers

Verification Date

August 2019

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Study Design Info

Observational Model: Other

Time Perspective: Other

Source: ClinicalTrials.gov