Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia Major

Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia Major

Sponsors

Lead sponsor: National Taiwan University Hospital

Source National Taiwan University Hospital
Brief Summary

Patient with thalassemia major have many endocrine diseases, such as hypopituitarism, hypothyroidism, hypoparathyroidis, osteoporosis, and etc.. These problems may be due to anemia itself or related to iron deposition. This study aimed to investigate the endocrine aspect of thalassemia major patients in Taiwan in order to introduce early intervention or treatment in the future.

Overall Status Recruiting
Start Date April 1, 2019
Completion Date April 1, 2020
Primary Completion Date April 1, 2020
Study Type Observational
Primary Outcome
Measure Time Frame
Abnormal bone mineral density rate 10 years
Secondary Outcome
Measure Time Frame
abnormal thyroid function rate 10 years
abnormal pituitary function rate 10 years
Enrollment 100
Condition
Eligibility

Sampling method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- Clinical diagnosis of Thalassemia major

- Patients of 20-85 years old

Exclusion Criteria:

- Patients younger than 20 years old.

- Patients older than 85 years old.

- Patients who are pregnant

Gender: All

Minimum age: 20 Years

Maximum age: 85 Years

Healthy volunteers: No

Overall Official
Last Name Role Affiliation
Shyang-Rong Shih, MD, PhD Study Director National Taiwan University Hospital
Overall Contact

Last name: Shyang-Rong Shih, MD, PhD

Phone: +886-972653337

Email: [email protected]

Location
facility status contact Shyang-Rong Shih Shyang-Rong Shih 886-23123456 [email protected]
Location Countries

Taiwan

Verification Date

May 2019

Responsible Party

Responsible party type: Sponsor

Has Expanded Access No
Condition Browse
Study Design Info

Observational model: Case-Only

Time perspective: Retrospective

Source: ClinicalTrials.gov