- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04122638
Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults
February 26, 2020 updated by: Filiz Demirdağ, Goztepe Training and Research Hospital
Prevalence of Sarcopenia and Sarcopenic Obesity in Community-dwelling Outpatient Older Adults
Syndromes such as sarcopenia, sarcopenic obesity and osteosarcopenic obesity are commonly seen in older adults.
They result from the impairment of muscle, bone and adipose tissue.
Thus, they lead to a decrease in quality of life and increase morbidity and mortality.
The aim of this study is to report the prevalence of sarcopenia, sarcopenic obesity and osteosarcopenic obesity in community-dwelling outpatient older adults and to investigate the related factors.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment (Actual)
572
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
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Istanbul, Turkey, 34722
- Goztepe Training and Research Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
65 years and older (OLDER_ADULT)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
Community-dwelling older adults
Description
Inclusion Criteria:
- Being at the age of 65 or older
- Being able to complete 4-m walk test
Exclusion Criteria:
- <24 points on Mini-Mental State Examination
- 12 points or higher on Geriatric Depression Scale
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Handgrip Strength
Time Frame: 10 minutes
|
Handgrip strength measured by Takei© Hand Dynamometer
|
10 minutes
|
Muscle mass
Time Frame: 5 minutes
|
Using Bioimpedance analysis (BİA) technique with TANITA© TBF 300
|
5 minutes
|
Bone density
Time Frame: 30 minutes
|
T score evaluation using Dual-energy X-ray absorptiometry (DEXA)
|
30 minutes
|
Percentage of body fat
Time Frame: 5 minutes
|
Using Bioimpedance analysis (BİA) technique with TANITA© TBF 300
|
5 minutes
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Gait speed
Time Frame: 3 minutes
|
4-m usual walking speed test
|
3 minutes
|
Physical Activity
Time Frame: 5-10 minutes
|
Using Rapid Assessment of Physical Activity (RAPA)
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5-10 minutes
|
Nutritional Status
Time Frame: 10 minutes
|
Assessed with Mini-Nutritional Assessment (MNA)
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10 minutes
|
Activities of Daily Living
Time Frame: 10 minutes
|
Activities of daily living assessed with Katz Index of Independence in Activities of Daily Living
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10 minutes
|
Instrumental Activities of Daily Living
Time Frame: 10 minutes
|
Instrumental activities of daily living assessed with Lawton -Brody Instrumental Activities of Daily Living Scale
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10 minutes
|
Depression
Time Frame: 10 minutes
|
Assessed with The Geriatric Depression Scale- Short Form
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10 minutes
|
Mini-Mental State Examination
Time Frame: 10-15 minutes
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Mini-Mental State Examination
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10-15 minutes
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Blood Sample Analysis
Time Frame: 5 minutes
|
A blood sample analysis including parameters such as: wbc, hgb, htc, mcv ,plt, fasting blood sugar, urea, uric acid, creatin, AST, ALP, ALT, GGT, LDH, total colesterol, trigylicerid, LDL, HDL, NA, K, Mg, Ca, P, Albumin, protrombin time, CRP, B12, folate, iron, ferritin, PTH, vitamin-D, sedimentation, TSH, T4, insukin, HGBA1C, IHOMA-IR.
|
5 minutes
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Comorbidities
Time Frame: 5 minutes
|
Assessed with Charlson Comorbidity Index
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5 minutes
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (ACTUAL)
October 7, 2019
Primary Completion (ACTUAL)
January 1, 2020
Study Completion (ACTUAL)
January 1, 2020
Study Registration Dates
First Submitted
October 7, 2019
First Submitted That Met QC Criteria
October 9, 2019
First Posted (ACTUAL)
October 10, 2019
Study Record Updates
Last Update Posted (ACTUAL)
February 28, 2020
Last Update Submitted That Met QC Criteria
February 26, 2020
Last Verified
February 1, 2020
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Metabolic Diseases
- Nervous System Diseases
- Neurologic Manifestations
- Overnutrition
- Nutrition Disorders
- Overweight
- Body Weight
- Musculoskeletal Diseases
- Neuromuscular Manifestations
- Pathological Conditions, Anatomical
- Bone Diseases
- Muscular Atrophy
- Atrophy
- Obesity
- Sarcopenia
- Osteoporosis
- Bone Diseases, Metabolic
Other Study ID Numbers
- GoztepeTRH
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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