The Effect of Perturbration on Balance Control in Adults

Balance control in respond to an unexpected platform perturbration during standing and walking: comparison between individuals with chronic ankle instability and healthy individuals.

Study Overview

• Status: Unknown
• Conditions: Chronic Ankle Instability

Detailed Description

An unexpected postural perturbration is a major risk factor of falls and injuries during gait. A postural perturbration is a sudden change in conditions that displaces the body posture away from equilibrium. Reactive postural control response is an immediate ( 70-120 ms ) automatic "like reflex" response which is initiated by unexpected postural perturbration in order to maintain balance. Even among young healthy adults there could be a problem in balance performance which does not become evident untill a slip or a trip or any other sudden perturbration happens. Thus a simple test of pertubration while standing or walking can identify a problem .

This study is comparing the reactive postural control of physical education students who suffer from chronic ankle instability (CAI) to healthy students on a Perturbation Treadmill. The device consists of a treadmill mounted on a moving force plate platform. The platform moves in the medial/ lateral plains to simulate a slip and a trip in both the standing and walking phase. Their reactive postural control is tested in a few conditions: standing on both legs - eyes open and eyes closed, in tandem standing, standing on one leg and in walking. In each condition the perturbration is given every 5-15 seconds in different speed and in unexpected direction (right /left). Lost of balance control is any change in the original location of the foot in standing conditions or stepping out of the treadmill.

• Study Type: Observational
• Enrollment (Anticipated): 100

Contacts and Locations

• Study Contact: Name: Alon Eliakim, MD; Phone Number: 972-9-7471596; Email: Eliakim.Alon@clalit.org.il
• Study Contact Backup: Name: Michal Pantanowitz, PhD; Phone Number: 972-9-7471596; Email: michal.pantanowitz@clalit.org.il

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 50 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Physical education students from Zinman College in Wingate

Description

Inclusion Criteria:

• age 18-50
• good health
• active people

Exclusion Criteria:

• Body weight greater than 135 kg
• Bone instability (non-consolidated fractures, unstable spinal column, severe osteoporosis)
• Head damage in the year prior to the study
• Diabetics or Unstable circulation
• Cardiac (blood) contraindications
• Vestibular problem
• Neurological deficits
• Mechanical ventilation problem
• Severe vascular disorders of the lower limbs

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Control
• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
static balance control in reaction to perturbration	The angle velocity at the ankle at the moment of loosing postural control while standing	20 minutes
dynamic balance control un reaction to perturbration	the speed of perturbration at the moment of loosing balance while walking	10 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to returning to original condition	How much time it takes to come back to the original step (Center of Pressure - COP) after the perturbration	30 minutes

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
movement inside the foot during balance control.	The changes in center of pressure (COP) amplitude height	30 minutes

Collaborators and Investigators

• Sponsor: Meir Medical Center

Study record dates

Study Major Dates

• Study Start (Anticipated): December 15, 2019
• Primary Completion (Anticipated): October 15, 2020
• Study Completion (Anticipated): December 15, 2020

Study Registration Dates

• First Submitted: October 3, 2019
• First Submitted That Met QC Criteria: November 20, 2019
• First Posted (Actual): November 22, 2019

Study Record Updates

• Last Update Posted (Actual): November 22, 2019
• Last Update Submitted That Met QC Criteria: November 20, 2019
• Last Verified: November 1, 2019

More Information

Terms related to this study

• Keywords: balance; Chronic ankle instability ( CAI ); Perturbration; reactive postural control; center of pressure - COP
• Other Study ID Numbers: MeirMc102-19CTIL

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No