Work Stress and Impact of Pruritus on Quality of Life (PRUERI)

Study of the Association Between Work Stress and the Impact of Pruritus on Quality of Life

Work stress and pruritus: imbalance of effort balance reward in patients with psoriasis.

Study Overview

• Status: Completed
• Conditions: Psoriasis

Detailed Description

Background. Stress increases the likelihood of psoriasis flare-up episodes and itching. Few studies have focused on work-related stress on such skin symptoms.

Objective. To study the association between work-related stress, pruritus and quality of life among workers suffering from psoriasis.

Methods. Investigators will conduct a monocentric non-interventional prospective study. Patients suffering from psoriasis will be recruited in both the Dermatology inpatient ward and outpatient clinic of Brest University Hospital . Included patients will be workers. Work-related stress will be assessed using the Effort-Reward Imbalance (ERI) model. The impact of pruritus on quality of life will be assessed with the Itchy Quality of Life (ItchyQoL) self-administered questionnaire. The collected data will include age, sex, body mass index, ordered medication to treat psoriasis, weekly working hours. The association between ERI and ItchyQoL scores will be studied using a univariate logistic regression.

• Study Type: Observational
• Enrollment (Actual): 30

Contacts and Locations

Study Locations

• France
  • Finistère
    • Brest, Finistère, France, 29609
      • Chru Brest

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Active and employed population, suffering from psoriasis, presenting for consultation or hospitalization of dermatology at the CHRU of Brest

Description

Inclusion Criteria:

• Major patients
• Active busy patients with psoriasis presenting for a dermatology consultation or hospitalization at the Brest CHRU
• Participation agreement

Exclusion Criteria:

• Presence of another potentially pruritic pathology
• No command of the French language
• Patient under legal protection (guardianship, curatorship, etc.)
• Refusal to participate

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Pruritus' impact on quality of life	The Itchy Quality of Life questionnaire (ItchyQoL) assess the quality of life linked to pruritus. It is a 22-item questionnaire wich assess the frequency of pruritus'symptoms in the past seven days. The score is between 22 and 110. The higher the score, the greater the impact of pruritus.	time required to complete the self questionnaire estimated at approximately 5 min immediately after consultation with the dermatologist

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Occupational stress	The effort-reward imbalance questionnaire in 23-item for occupational stress. Six items make it possible to calculate the extrinsic efforts felt (score e) and eleven items assess the rewards perceived by the employee (score r). The ERI score is then calculated as follows: Ratio = (11 x e) / (6 x (66 - r)) (e: effort scale score, r: rewards scale score). A ratio greater than one indicates an imbalance in favor of efforts. The last six items make it possible to calculate the score for intrinsic efforts (over commitement). They relate to the inability to get away from work, impatience and disproportionate irritability.	time required to complete the self questionnaire estimated at approximately 5 min immediately after consultation with the dermatologist

Collaborators and Investigators

• Sponsor: University Hospital, Brest

Study record dates

Study Major Dates

• Study Start (Actual): March 9, 2020
• Primary Completion (Actual): June 30, 2020
• Study Completion (Actual): June 30, 2020

Study Registration Dates

• First Submitted: March 6, 2020
• First Submitted That Met QC Criteria: March 18, 2020
• First Posted (Actual): March 20, 2020

Study Record Updates

• Last Update Posted (Actual): July 7, 2020
• Last Update Submitted That Met QC Criteria: July 2, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Keywords: Psoriasis; Quality of life; Pruritus; Occupational stress
• Additional Relevant MeSH Terms: Skin Diseases; Skin Diseases, Papulosquamous; Skin Manifestations; Psoriasis; Pruritus
• Other Study ID Numbers: 29BRC19.0263

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No