- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04454333
COVID-19 in Pain Perspective
Study Overview
Detailed Description
This retrospectively designed study was carried out by analyzing SARS-CoV-2 infected and hospitalized patients in our hospital for 2 month. The patients, whose contact information can be accessed from the hospital records, will be called by phone and pain inquiries were made during the SARS-CoV-2 infection process. In addition, patients' demographic data, living conditions (number and characteristics of the person in the household), comorbidities, symptom inquiry related to infection, duration of symptoms, length of hospitalstay, pre-infection pain conditions and current pain, anxiety, depression levels and quality of life will be questioned.
The pain questioning include the painful body region/s, severity (Numeric Rating Scale), type of analgesic drugs used, and duration of use that occurred during infection. Anxiety and depression levels will be evaluated, hospital anxiety and depression scale (HADS), and quality of life will be evaluated with SF-12 health assessment questionnaire.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
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Istanbul, Turkey
- Sisli Hamidiye Etfal Training and Research Hospital
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients with positive PCR test results obtained from combined throat and nasopharyngeal swab samples
- patients consistent with Covid-19 infection as a result of thorax computed tomography, although PCR test results were negative.
Exclusion Criteria:
- Patients who have undergone surgery and trauma in the painful area in the past 3 months,
- Patients with pathological disease that can cause underlying pain
- Pregnant women
- Those who have psychiatric illness and use psychiatric drugs
- Presence of malignancy
- Patients with severe cognitive deficits
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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Hospitalized caused by COVID-19
A total of 466 patients hospitalized with the diagnosis of SARS-COV-2 at the University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital were retrospectively screened.
212 of these patients did not answer the calls, 34 of them could not be reached because they gave the wrong phone number beforehand. 4 of the patients called by the phone had communication problems due to language problems and 10 people did not want to fill the questionnaire.
206 of them were contacted by the phone and their pain and myalgia in the head, neck-back, waist, shoulder and hip regions before, during and after SARS-COV-2, their anxiety and depression levels after SARS-COV-2, and their quality of life were questioned.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
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Numeric Rating Scale for Pain
Time Frame: up to 10 weeks
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Evaluation of severity of pain for head, back-neck and extremities by Numeric Rating Scale.
Scoring will be done between 0 minimum and 10 maximum values.
Higher scores mean worse outcome.
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up to 10 weeks
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Hospital Anxiety and Depression Scale (HADS)
Time Frame: up to 10 weeks
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Evaluation of patient's anxiety and depression level in hospital by Hospital Anxiety and Depression Scale (HADS).
The Hospital Anxiety and Depression Scale (HADS) is a 14-item self-report screening scale.
It contains two 7-item scales: one for anxiety and one for depression both with a score range of 0-21.
Higher scores mean a worse outcome.
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up to 10 weeks
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SF-12 Health assesment Questionaire
Time Frame: up to 10 weeks
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Evaluation of patient's quality of life by SF-12 Health assesment Questionaire.
Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12).
The scores may be reported as Z-scores (difference compared to the population average, measured in standard deviations).
Higher scores mean a better outcome.
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up to 10 weeks
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Collaborators and Investigators
Investigators
- Principal Investigator: Aylin Ayyıldız, MD, Sisli Hamidiye Etfal Training and Research Hospital
Publications and helpful links
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2811
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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