Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation (DOP-RENAL)

December 23, 2020 updated by: University Hospital, Strasbourg, France

Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation - Interest in Predicting the Occurence of Acute Postoperative Renal Faillure

Liver transplantation is associated with a modification of the perfusion pressures of the abdominal organs (preoperative portal hypertension in connection with liver pathology, and normalization of the perfusion pressures during surgery). This abrupt change in the infusion regime is probably responsible for an alteration in renal function in some patients, and the identification of renal vascular profiles using Doppler could point to pathological profiles, which should be diagnosed early.

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • France
      • Strasbourg, France, 67091
        • Recruiting
        • Strasbourg University Hospitals - Anesthesia-intensive care unit
        • Contact:
        • Principal Investigator:
          • Julien POTTECHER, MD, PhD
        • Sub-Investigator:
          • Kevin COGNE, MD
        • Sub-Investigator:
          • Cédric MUNSCH, MD
        • Sub-Investigator:
          • Benjamin LEBAS, MD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Adult patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30, 2020

Description

Inclusion Criteria:

  • Patient of full age (≥18 years)
  • Patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30, 2020.
  • Patients having undergone an evaluation of hepatic and renal vascular profiles perioperatively.
  • Patients hospitalized in the surgical intensive care unit after hepatic transplant surgery.
  • Patient not having expressed, after information, the reuse of his data for the purposes of this research

Exclusion Criteria:

  • Patient who expressed his opposition to participating in the study
  • Patient with suspected obstructive acute renal failure
  • Stenosis of renal arteries known at the time
  • End-stage renal disease on dialysis
  • Impossibility of giving the subject informed information (difficulties in understanding the subject, etc.)
  • Subject under safeguard of justice

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Retrospective analysis of the development profiles of renal dopplers in perioperative liver transplantation
Time Frame: Files analysed retrospectily from July 1st, 2019 to June 30, 2020 will be examined
Files analysed retrospectily from July 1st, 2019 to June 30, 2020 will be examined

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital, Strasbourg, France

Investigators

  • Study Director: Julien POTTECHER, MD, PhD, Strasbourg University Hospitals - Anesthesia-intensive care unit

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 25, 2020

Primary Completion (Anticipated)

May 25, 2022

Study Completion (Anticipated)

May 25, 2022

Study Registration Dates

First Submitted

December 18, 2020

First Submitted That Met QC Criteria

December 18, 2020

First Posted (Actual)

December 23, 2020

Study Record Updates

Last Update Posted (Actual)

December 28, 2020

Last Update Submitted That Met QC Criteria

December 23, 2020

Last Verified

December 1, 2020

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 8059

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Acute Renal Failure

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ukraine

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe