Anemia in Older Adults

March 25, 2021 updated by: Vanessa De la Cruz, Instituto Nacional de Salud Publica, Mexico

Identification of the Main Causes of Anemia in Older Adults

A cross-sectional study with 829 older Mexican adults were recruited from July to September 2015, from four localities in the southern region of México. Older adults were interviewed at their homes and a fasting blood sample was obtained for analysis of micronutrient status (iron deficiency, vitamin B12 deficiency, folate deficiency, vitamin A deficiency and biomarkers of inflammation). The aim of the study was to identify the main causes of anemia in older adults with higher rates of anemia according to the recent data of the Mexican National Health and Nutrition Survey.

Study Overview

Detailed Description

A survey with cross-sectional design was applied in 829 older Mexican adults, recruited during the period July to September 2015, from four localities in the southern region of México: including Champotón, Campeche, Mérida, and Valladolid. Older adults were interviewed at their homes to collect nutrition, health, cognitive and dietary information. Anthropometric measures and functionallity tests were also collected. A finger prick capillary blood sample was collected to measure hemoblobin in situ using HemoCue. Anemia was defined according to WHO criteria. A fasting venous blood sample was collected in 803 older adults. Serum was separated and frozen at -20°C to measure ferritin, retinol, vitamin B12, folate, iron, soluble transferrin receptor, C-reactive protein, interleukin 6, alpha glycoprotein 1, hepcidin, erythropoietin in the laboratory of nutrition of the National Institute of Public Health.

The study protocol was approved by Research, Biosecurity and Ethics Committees of the National Institute of Public Health. Participants received a detailed explanation of the study procedures and signed an informed consent form prior to data collection.

Study Type

Observational

Enrollment (Actual)

829

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Older adults >=60 years living in urban localities from the southern region of Mexico ( Champotón, Valladolid, Campeche and Yucatán) were visited at their homes. 60% of the total sample were women and the rest men.

Description

Inclusion Criteria:

  • Community-dwelling older adults who wish to participate in the study
  • Ambulatory older adultos
  • Older adult with own decision making

Exclusion Criteria:

  • Non demented
  • Non oxygen dependent
  • No disability

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Anemia
Time Frame: July- September 2015
Hemoglobin measure in capillary blood sample
July- September 2015

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 1, 2015

Primary Completion (Actual)

September 1, 2015

Study Completion (Actual)

September 1, 2015

Study Registration Dates

First Submitted

March 25, 2021

First Submitted That Met QC Criteria

March 25, 2021

First Posted (Actual)

March 29, 2021

Study Record Updates

Last Update Posted (Actual)

March 29, 2021

Last Update Submitted That Met QC Criteria

March 25, 2021

Last Verified

March 1, 2021

More Information

Terms related to this study

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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