Influence of Different Ankle Positions on Nerve Conduction Parameters of Deep Peroneal Nerve

BACKGROUND:

The deep peroneal nerve arises as a branch of the common peroneal nerve which courses around the neck of the fibula. The motor component of deep peroneal nerve is responsible for innervating the anterior compartment of the lower leg which includes the tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus tertius muscles.

Nerve conduction velocity shortly known as "NCV" tests are used determine the speed of the electrical signals moving along a specific peripheral nerve .This will be helpful in localizing the site of entrapment of peripheral nerves and useful for assessing both recovery and prognosis of any injury to peripheral nervesthere are numerous aspects that could influence nerve conduction study.

Although changes in joint position have been reported in several studies to affect nerve conduction velocity of peripheral nerves. the effect of changing ankle joint position on deep peroneal NCV has not been repor Purpose

This study will investigate the effect of different ankle positions on:

1. Deep peroneal nerve distal motor latency across ankle joint.
2. Deep peroneal nerve sensory onset latency across ankle joint

Study Overview

• Status: Completed
• Conditions: Healthy Subjects

Detailed Description

31healthy subjects of both genders with age ranging from 20to 40years old were examined for motor distal latency and sensory onset latency at three different ankle positions :neutral,20degrees dorsiflexion and 40degrees plantar flexion

• Study Type: Observational
• Enrollment (Actual): 31

Contacts and Locations

• Study Contact: Name: Mahmoud Salah; Phone Number: 01068419431; Email: mahmoud.salah@cu.edu.eg

Study Locations

• Egypt
  • Aga, Egypt, 055555
    • Mahmoud Salah

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 40 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

31 healthy subjects of both genders will be recruited to participate in this study

Description

Inclusion criteria:

• Healthy subjects.
• Age ranges from 20 to 40 years because longer latencies and slower nerve conduction velocity are seen significantly with increasing age.
• All participants will be selected with body mass index (BMI) between 18.5 and 24.9kg/cm2 .

Exclusion criteria:

• Elderly subjects.
• Pregnant women.
• Subjects with history of or risk factors for peripheral nerve lesions.
• Obese subjects.
• Subjects with any foot deformity.
• History of lower limb fractures.
• History of surgery to lower limbs
• Diabetic patients.
• Patients with cardiovascular disorders.
• Hypertensive patients.
• Women wearing high heeled shoes.

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Deep peroneal nerve motor distal latency	Motor distal latency: It is the time between the distal stimulus and the onset of compound muscle action potential(CMAP)at recording muscles	30 minutes for each participant
Deep peroneal nerve sensory onset latency	: It is the time taken from the stimulus artifact to the initial negative deflection of the sensory nerve action potential (SNAP)	30 minutes for each participant

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Principal Investigator: Mahmoud Salah, Faculty of physical therapy

Study record dates

Study Major Dates

• Study Start (Actual): December 5, 2022
• Primary Completion (Actual): January 3, 2023
• Study Completion (Actual): January 26, 2023

Study Registration Dates

• First Submitted: November 23, 2022
• First Submitted That Met QC Criteria: November 23, 2022
• First Posted (Actual): December 2, 2022

Study Record Updates

• Last Update Posted (Estimate): January 30, 2023
• Last Update Submitted That Met QC Criteria: January 27, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: P.T.REC/012/004076

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No