Clinical Trials
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NCTID/Status
Study
Last Changed
1
NCT03926780
Recruiting
Recruiting
Comparative Study of Oral Anticoagulation in Left Ventricular Thrombi
Conditions: Anticoagulants; Increased; Left Ventricular Thrombosis
Intervention: Rivaroxaban 20 MG, Warfarin Sodium
Conditions: Anticoagulants; Increased; Left Ventricular Thrombosis
Intervention: Rivaroxaban 20 MG, Warfarin Sodium
April 23, 2019
2
NCT03926767
Not yet recruiting
Not yet recruiting
Additional Effect of Pain Neuroscience Education to Orofacial and Neck Exercises in Temporomandibular Disorders
Conditions: Temporomandibular Disorders
Intervention: Pain Neuroscience Education (PNE), Orofacial Manual Therapy, Orofacial Exercises, Neck Motor Control Exercises
Conditions: Temporomandibular Disorders
Intervention: Pain Neuroscience Education (PNE), Orofacial Manual Therapy, Orofacial Exercises, Neck Motor Control Exercises
April 23, 2019
3
NCT03926754
Enrolling by invitation
Enrolling by invitation
Beta 3 Agonist Treatment in Heart Failure-2
Conditions: Heart Failure With Reduced Ejection Fraction NYHA Class III-IV
Intervention: Mirabegron
Conditions: Heart Failure With Reduced Ejection Fraction NYHA Class III-IV
Intervention: Mirabegron
April 23, 2019
4
NCT03926741
Not yet recruiting
Not yet recruiting
April 23, 2019
5
NCT03926728
Not yet recruiting
Not yet recruiting
Safety and Immunogenicity of a Chlamydia Vaccine CTH522
Conditions: Trachoma
Intervention: CTH522-CAF01 IM, CTH522-CAF09b IM, CTH522 ID, CTH522 TO, Placebo (Saline)
Conditions: Trachoma
Intervention: CTH522-CAF01 IM, CTH522-CAF09b IM, CTH522 ID, CTH522 TO, Placebo (Saline)
April 23, 2019
6
NCT03926715
Recruiting
Recruiting
Prevalence of Malnutrition in Surgery
Conditions: Malnutrition; Surgery; Cancer
Intervention: Nutritional Status
Conditions: Malnutrition; Surgery; Cancer
Intervention: Nutritional Status
April 23, 2019
7
NCT03926702
Not yet recruiting
Not yet recruiting
Tau Imaging With JNJ067
Conditions: Alzheimer Disease; Mild Cognitive Impairment; Progressive Supranuclear Palsy
Intervention: Radiopharmaceuticals
Conditions: Alzheimer Disease; Mild Cognitive Impairment; Progressive Supranuclear Palsy
Intervention: Radiopharmaceuticals
April 22, 2019
8
NCT03926689
Not yet recruiting
Not yet recruiting
SMS Messages to Increase Child Egg Consumption, a C-rct in Nepal
Conditions: Dietary Habits
Intervention: SMS Messages, Standard SII SBCC
Conditions: Dietary Habits
Intervention: SMS Messages, Standard SII SBCC
April 23, 2019
9
NCT03926676
Recruiting
Recruiting
Comparing Nano Hybrid Composite Blocks With Ceramic Blocks in Indirect Restorations 2. Protocol Registration:
Conditions: the Clinical Performance of Indirect Restoration Fabricated From Nanohybrid Cad Cam Composite Blocks and Ceramic Blocks
Intervention: Grandio Blocks, Emax
Conditions: the Clinical Performance of Indirect Restoration Fabricated From Nanohybrid Cad Cam Composite Blocks and Ceramic Blocks
Intervention: Grandio Blocks, Emax
April 22, 2019
10
NCT03926663
Not yet recruiting
Not yet recruiting
Intranasal Injection of Dexmedetomidine and Bupivacaine in Septoplasty Surgeries
Conditions: Intranasal Dexmedetomidine; Intranasal Bupivacaine; Septoplasty Surgeries
Intervention: Dexmedetomidine, Bupivacaine
Conditions: Intranasal Dexmedetomidine; Intranasal Bupivacaine; Septoplasty Surgeries
Intervention: Dexmedetomidine, Bupivacaine
April 22, 2019
11
NCT03926650
Recruiting
Recruiting
The Correlation Between the Frontal Electromyography Parameter in Patient State Index (PSI) Monitor and Train of Four
Conditions: Muscle Relaxation
Intervention: Masimo Sedline Monitor Patient State Index
Conditions: Muscle Relaxation
Intervention: Masimo Sedline Monitor Patient State Index
April 22, 2019
12
NCT03926637
Not yet recruiting
Not yet recruiting
Feasibility of the Multiple Sclerosis Performance Test in Participants With Multiple Sclerosis
Conditions: Multiple Sclerosis
Intervention: Multiple Sclerosis Performance Test (MSPT)
Conditions: Multiple Sclerosis
Intervention: Multiple Sclerosis Performance Test (MSPT)
April 22, 2019
13
NCT03926624
Not yet recruiting
Not yet recruiting
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd Salvage
Conditions: Leukemia, Myeloid, Acute
Intervention: DFP-10917, Cytarabine, Azacitidine, Decitabine, Mitoxantrone, Etoposide, Fludarabine, Idarubicin
Conditions: Leukemia, Myeloid, Acute
Intervention: DFP-10917, Cytarabine, Azacitidine, Decitabine, Mitoxantrone, Etoposide, Fludarabine, Idarubicin
April 23, 2019
14
NCT03926611
Not yet recruiting
Not yet recruiting
Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistamines
Conditions: Chronic Spontaneous Urticaria
Intervention: LOU064 Arm 1, LOU064 Arm 2, LOU064 Arm 3, LOU064 Arm 4, LOU064 Arm 5, LOU064 Arm 6, Placebo Arm
Conditions: Chronic Spontaneous Urticaria
Intervention: LOU064 Arm 1, LOU064 Arm 2, LOU064 Arm 3, LOU064 Arm 4, LOU064 Arm 5, LOU064 Arm 6, Placebo Arm
April 23, 2019
15
NCT03926598
Not yet recruiting
Not yet recruiting
Guide To Goals: A Novel Care Coordination Tool for Children With Type Two Diabetes (T2D)
Conditions: Type2 Diabetes Mellitus
Intervention: Patient And/or Family Member Intervention, Certified Diabetes Educator Intervention, Physician Intervention, Front Desk Staff Intervention, Nurse Intervention
Conditions: Type2 Diabetes Mellitus
Intervention: Patient And/or Family Member Intervention, Certified Diabetes Educator Intervention, Physician Intervention, Front Desk Staff Intervention, Nurse Intervention
April 23, 2019
16
NCT03926585
Not yet recruiting
Not yet recruiting
Variations in the DIO2 and MCT10 Genes and Effect of Triiodothyronine Treatment
Conditions: Hypothyroidism
Conditions: Hypothyroidism
April 23, 2019
17
NCT03926572
Not yet recruiting
Not yet recruiting
Acute Decompensation of Pulmonary Hypertension
Conditions: Hypertension, Pulmonary; Biomarkers
Intervention: A Biobank Will Be Created From Blood Samples Taken At Admission, Days 3 And Days 7
Conditions: Hypertension, Pulmonary; Biomarkers
Intervention: A Biobank Will Be Created From Blood Samples Taken At Admission, Days 3 And Days 7
April 23, 2019
18
NCT03926559
Recruiting
Recruiting
The Effect of Neuraxial Morphine (Duramorph) on Pain Control
Conditions: Perineal Tear
Intervention: Morphine.
Conditions: Perineal Tear
Intervention: Morphine.
April 23, 2019
19
NCT03926546
Not yet recruiting
Not yet recruiting
Individual Versus Group Exposure With Response Prevention (ERP) for the Treatment of Obsessive Compulsive Disorder (OCD)
Conditions: OCD
Intervention: ERP For Individuals
Conditions: OCD
Intervention: ERP For Individuals
April 23, 2019
20
NCT03926533
Not yet recruiting
Not yet recruiting
Telehealth-Enhanced Patient-Oriented Recovery Trajectory After ICU
Conditions: Critical Illness; Acute Respiratory Distress Syndrome; Septic Shock
Intervention: Telehealth
Conditions: Critical Illness; Acute Respiratory Distress Syndrome; Septic Shock
Intervention: Telehealth
April 23, 2019
21
NCT03926520
Not yet recruiting
Not yet recruiting
Electroconvulsive Therapy (ECT) for Agitation in Alzheimer's Dementia (AD)
Conditions: Alzheimer Dementia; Agitation,Psychomotor
Intervention: Electroconvulsive Therapy (ECT), Simulated Electroconvulsive Therapy (S-ECT)
Conditions: Alzheimer Dementia; Agitation,Psychomotor
Intervention: Electroconvulsive Therapy (ECT), Simulated Electroconvulsive Therapy (S-ECT)
April 23, 2019
22
NCT03926507
Not yet recruiting
Not yet recruiting
F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery
Conditions: Glioblastoma
Intervention: Computed Tomography, Fluciclovine F18, Positron Emission Tomography
Conditions: Glioblastoma
Intervention: Computed Tomography, Fluciclovine F18, Positron Emission Tomography
April 23, 2019
23
NCT03926494
Not yet recruiting
Not yet recruiting
Carbon Monoxide-induced Coma: Prognostic Factors
Conditions: Coma; Carbon Monoxide Poisoning
Conditions: Coma; Carbon Monoxide Poisoning
April 23, 2019
24
NCT03926481
Not yet recruiting
Not yet recruiting
Evaluation of the Healthy Lifestyle Program on Cognitive Outcomes
Conditions: Obesity
Intervention: Evaluate Healthy Lifestyle Program On Cognitive Outcomes
Conditions: Obesity
Intervention: Evaluate Healthy Lifestyle Program On Cognitive Outcomes
April 23, 2019
25
NCT03926468
Not yet recruiting
Not yet recruiting
Liquid Biopsy in Head and Neck Cancer
Conditions: Head and Neck Squamous Cell Carcinoma
Intervention: Liquid Biopsy
Conditions: Head and Neck Squamous Cell Carcinoma
Intervention: Liquid Biopsy
April 23, 2019
26
NCT03926455
Completed
Completed
Safety and Immunogenicity of Typhax, a Typhoid Vaccine
Conditions: Typhoid Fever
Intervention: Typhax (investigational Typhoid Fever Candidate Vaccine), Placebo, Active Comparator Typhim Vi
Conditions: Typhoid Fever
Intervention: Typhax (investigational Typhoid Fever Candidate Vaccine), Placebo, Active Comparator Typhim Vi
April 23, 2019
27
NCT03926442
Recruiting
Recruiting
Spices, Inflammation and Vascular Response in Humans
Conditions: Healthy
Intervention: Italian Herb Meal, Cinnamon Meal, Pumpkin Spice Meal, Placebo Meal
Conditions: Healthy
Intervention: Italian Herb Meal, Cinnamon Meal, Pumpkin Spice Meal, Placebo Meal
April 23, 2019
28
NCT03926429
Completed
Completed
Features and Outcomes of Patients With Reactive Arthritis
Conditions: Arthritis
Intervention: Standardised Data Collection
Conditions: Arthritis
Intervention: Standardised Data Collection
April 23, 2019
29
NCT03926416
Completed
Completed
Safety Study of Live Attenuated Influenza Vaccine, CodaVax
Conditions: Influenza
Intervention: CodaVax-H1N1, Fluzone Quadrivalent, Placebo
Conditions: Influenza
Intervention: CodaVax-H1N1, Fluzone Quadrivalent, Placebo
April 23, 2019
30
NCT03926403
Not yet recruiting
Not yet recruiting
Evaluation of the Effectiveness of Hypnosis Support on Patient Perception of Outpatient Surgery Under Local Anaesthesia
Conditions: Hypnosis; Local Anaesthesia; Outpatient Surgery; FACE
Intervention: State-Trait Anxiety Inventory ("Spielberger Self-Assessment Questionnaire"), Hypnosis Techniques, Local Anaesthesia
Conditions: Hypnosis; Local Anaesthesia; Outpatient Surgery; FACE
Intervention: State-Trait Anxiety Inventory ("Spielberger Self-Assessment Questionnaire"), Hypnosis Techniques, Local Anaesthesia
April 23, 2019
31
NCT03926390
Completed
Completed
Gut Priming With Oral Bovine Colostrum for Preterm Neonates; Randomized Control Trial
Conditions: Late Onset Neonatal Sepsis; Necrotizing Enterocolitis of Newborn
Intervention: Bovine Colostrum, Placebo
Conditions: Late Onset Neonatal Sepsis; Necrotizing Enterocolitis of Newborn
Intervention: Bovine Colostrum, Placebo
April 23, 2019
32
NCT03926377
Not yet recruiting
Not yet recruiting
Influence of Dermocorticoids on Bone Mineral Density in Patients With Bullous Pemphigoid
Conditions: Osteoporosis; Bullous Pemphigoid
Conditions: Osteoporosis; Bullous Pemphigoid
April 23, 2019
33
NCT03926364
Recruiting
Recruiting
Profile of Pain and Unpleasant Sensations in Patients With Referred Pain
Conditions: Referred Pain; Somatic Pain; Neuropathic Pain
Intervention: Patients With Referred Pain
Conditions: Referred Pain; Somatic Pain; Neuropathic Pain
Intervention: Patients With Referred Pain
April 23, 2019
34
NCT03926351
Recruiting
Recruiting
High Dose Omega 3 in People at Risk for Dementia
Conditions: Dementia; Inflammation; Mild Cognitive Impairment; Cognitive Decline; SCD; Cognitive Dysfunction; Pathologic Processes; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorder; Cognition Disorders
Intervention: Omega-3 Capsules, Olive Oil
Conditions: Dementia; Inflammation; Mild Cognitive Impairment; Cognitive Decline; SCD; Cognitive Dysfunction; Pathologic Processes; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorder; Cognition Disorders
Intervention: Omega-3 Capsules, Olive Oil
April 23, 2019
35
NCT03926338
Recruiting
Recruiting
Toripalimab With or Without Celecoxib as Neoadjuvant Therapy in Resectable dMMR/MSI-H Colon Cancer
Conditions: Colon Cancer; MSI-H
Intervention: Neoadjuvant Therapy With PD-1 Inhibitor Plus COX Inhibitor, Neoadjuvant Therapy With PD-1 Inhibitor
Conditions: Colon Cancer; MSI-H
Intervention: Neoadjuvant Therapy With PD-1 Inhibitor Plus COX Inhibitor, Neoadjuvant Therapy With PD-1 Inhibitor
April 22, 2019
36
NCT03926325
Not yet recruiting
Not yet recruiting
Baseline Investigation of Patients With Cardiac Arrest in China
Conditions: Cardiac Arrest
Conditions: Cardiac Arrest
April 22, 2019
37
NCT03926312
Not yet recruiting
Not yet recruiting
Smart Device-based Cardiac Rehabilitation After Myocardial Intervention
Conditions: Myocardial Infarction
Intervention: Smart Device-based Cardiac Rehabilitation
Conditions: Myocardial Infarction
Intervention: Smart Device-based Cardiac Rehabilitation
April 23, 2019
38
NCT03926299
Not yet recruiting
Not yet recruiting
Clinical Trial to Demonstrate That the Dual Laser Therapy is Effective for the Treatment of Vulvar Lichen Sclerosus
Conditions: Chronic Skin Disease; Vulvar Lichen Sclerosus
Intervention: FotonaSmooth SP® Spectro Laser Device, Clobetasol Propionate 0.05% Ointment
Conditions: Chronic Skin Disease; Vulvar Lichen Sclerosus
Intervention: FotonaSmooth SP® Spectro Laser Device, Clobetasol Propionate 0.05% Ointment
April 23, 2019
39
NCT03926286
Recruiting
Recruiting
Fecal Microbial Transplant (FMT) for Sjogrens Syndrome
Conditions: Sjogren's Syndrome
Intervention: FMP-30
Conditions: Sjogren's Syndrome
Intervention: FMP-30
April 23, 2019
40
NCT03926273
Completed
Completed
Serum and Urine Ghrelin in Adult Epileptic Patients
Conditions: Epilepsy
Conditions: Epilepsy
April 22, 2019
41
NCT03926260
Not yet recruiting
Not yet recruiting
Early Assessment of Response to Treatment of Metastatic LUng Tumors Based on CIrculating Tumor DNA
Conditions: Metastatic Non-small Cell Lung Cancer
Intervention: CtDNA Analysis
Conditions: Metastatic Non-small Cell Lung Cancer
Intervention: CtDNA Analysis
April 23, 2019
42
NCT03926247
Recruiting
Recruiting
Immigrant Well-being Project: Transdisciplinary Ecological Mental Health Intervention for Mexican Immigrants
Conditions: Mental Health
Intervention: Immigrant Well-Being Project
Conditions: Mental Health
Intervention: Immigrant Well-Being Project
April 22, 2019
43
NCT03926234
Recruiting
Recruiting
Effectiveness of a Four-level Chinese Emergency Triage Scale in Mainland China
Conditions: Emergencies; Triage
Intervention: Four-level Chinese Emergency Triage Scale
Conditions: Emergencies; Triage
Intervention: Four-level Chinese Emergency Triage Scale
April 22, 2019
44
NCT03926221
Recruiting
Recruiting
Parent-Adolescent Interpersonal Processes in the Science of Behavior Change
Conditions: Sleep Deprivation; Adolescent Behavior
Intervention: Parent Behavior Change Intervention (PBC-I) And Transdiagnostic Sleep And Circadian Intervention (TranS-C)
Conditions: Sleep Deprivation; Adolescent Behavior
Intervention: Parent Behavior Change Intervention (PBC-I) And Transdiagnostic Sleep And Circadian Intervention (TranS-C)
April 22, 2019
45
NCT03926208
Not yet recruiting
Not yet recruiting
Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Conditions: Postoperative Infection; Postoperative Complications
Intervention: Soak And Scrub, Clorihexadine Scrub
Conditions: Postoperative Infection; Postoperative Complications
Intervention: Soak And Scrub, Clorihexadine Scrub
April 23, 2019
46
NCT03926195
Not yet recruiting
Not yet recruiting
Study to Evaluate the Effect of Filgotinib on Semen Parameters in Adult Males With Active Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, or Non-radiographic Axial Spondyloarthritis
Conditions: Rheumatoid Arthritis; Psoriatic Arthritis; Ankylosing Spondylitis; Non-Radiographical Axial Spondyloarthritis
Intervention: Filgotinib, Placebo, Standard Of Care
Conditions: Rheumatoid Arthritis; Psoriatic Arthritis; Ankylosing Spondylitis; Non-Radiographical Axial Spondyloarthritis
Intervention: Filgotinib, Placebo, Standard Of Care
April 19, 2019
47
NCT03926182
Not yet recruiting
Not yet recruiting
Study to Determine the Effect of Food on the Blood Levels of AST2818 Following Single Oral Doses in Healthy Male Volunteers
Conditions: Healthy Male Volunteers
Intervention: AST2818 Tablets, AST2818 Tablets
Conditions: Healthy Male Volunteers
Intervention: AST2818 Tablets, AST2818 Tablets
April 23, 2019
48
NCT03926169
Not yet recruiting
Not yet recruiting
A Global Study Comparing Risankizumab to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Conditions: Hidradenitis Suppurativa
Conditions: Hidradenitis Suppurativa
April 23, 2019
49
NCT03926156
Not yet recruiting
Not yet recruiting
RIvoraxaban in Mitral Stenosis
Conditions: Mitral Stenosis; Rheumatic Heart Disease
Intervention: Rivaroxaban, Warfarin
Conditions: Mitral Stenosis; Rheumatic Heart Disease
Intervention: Rivaroxaban, Warfarin
April 22, 2019
50
NCT03926143
Not yet recruiting
Not yet recruiting
A Clinical Study of Anetumab Ravtansine in Adults With Solid Tumors Who Have Been Treated in Previous Bayer-sponsored Anetumab Ravtansine Studies
Conditions: Cancer
Conditions: Cancer
April 23, 2019
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 … 6058 6059 6060 6061 6062 6063 6064 6065 6066 6067 6068 6069 6070 6071 6072 6073 6074 6075 6076 6077 Next Last
Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.