Clinical Trials
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NCTID/Status
Study
Last Changed
1
NCT04195464
Recruiting
Recruiting
Effects of Dry Needling on Muscle Function in Patients With Hip Osteoarthritis
Conditions: Osteoarthritis
Intervention: Dry Needling, Sham Dry Needling
Conditions: Osteoarthritis
Intervention: Dry Needling, Sham Dry Needling
December 10, 2019
2
NCT04195451
Not yet recruiting
Not yet recruiting
RE-ENERGIZE FONTAN: A RandomizEd Exercise INtERvention DesiGned to MaximIZE Fitness in Pediatric FONTAN Patients
Conditions: Single-ventricle
Intervention: Live-Video-Supervised Exercise Intervention, Usual Care Then Live-Video Supervised Exercise Intervention
Conditions: Single-ventricle
Intervention: Live-Video-Supervised Exercise Intervention, Usual Care Then Live-Video Supervised Exercise Intervention
December 9, 2019
3
NCT04195438
Recruiting
Recruiting
Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy
Conditions: Liver Cancer
Intervention: CO Testing Pre/Post Hepatic Resection, ABG Testing Pre/Post Hepatic Resection, CT Evaluations
Conditions: Liver Cancer
Intervention: CO Testing Pre/Post Hepatic Resection, ABG Testing Pre/Post Hepatic Resection, CT Evaluations
December 9, 2019
4
NCT04195425
Not yet recruiting
Not yet recruiting
Breastfeeding and Gut Health
Conditions: Gut Health
Conditions: Gut Health
December 10, 2019
5
NCT04195412
Recruiting
Recruiting
Imaging the Effects of Bihemispheric Transcranial Stimulation and Motor Training After Stroke.
Conditions: Stroke
Conditions: Stroke
December 9, 2019
6
NCT04195399
Not yet recruiting
Not yet recruiting
A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery
Conditions: Desmoid-Type Fibromatosis; Recurrent Desmoid-Type Fibromatosis; Unresectable Desmoid-Type Fibromatosis
Intervention: Nirogacestat, Quality-of-Life Assessment, Questionnaire Administration
Conditions: Desmoid-Type Fibromatosis; Recurrent Desmoid-Type Fibromatosis; Unresectable Desmoid-Type Fibromatosis
Intervention: Nirogacestat, Quality-of-Life Assessment, Questionnaire Administration
December 9, 2019
7
NCT04195386
Recruiting
Recruiting
Efficacy of a Chemically Activated Composite Resin Alkasite in Atypical Caries Lesions of Deciduous Teeth
Conditions: Dental Caries in Children
Conditions: Dental Caries in Children
December 9, 2019
8
NCT04195373
Not yet recruiting
Not yet recruiting
A Safety Study of TMV-018 in Patients With Tumors of the Gastrointestinal Tract
Conditions: Gastrointestinal Cancer
Conditions: Gastrointestinal Cancer
December 9, 2019
9
NCT04195360
Recruiting
Recruiting
Postoperative Incidence of Orthostatic Intolerance and Hypotension in Primary Unicompartmental Knee Arthroplasty (UKA)
Conditions: Orthostatic Hypotension; Orthostatic Intolerance; Postoperative Complications
Conditions: Orthostatic Hypotension; Orthostatic Intolerance; Postoperative Complications
December 10, 2019
10
NCT04195347
Not yet recruiting
Not yet recruiting
Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase
Conditions: Acute Pancreatitis
Conditions: Acute Pancreatitis
December 9, 2019
11
NCT04195334
Not yet recruiting
Not yet recruiting
IMN Diameter to Femoral Canal Diameter and Union
Conditions: Femoral Shaft Fracture
Conditions: Femoral Shaft Fracture
December 9, 2019
12
NCT04195321
Not yet recruiting
Not yet recruiting
Norepinephrine Versus Phenylephrine for Preventing Spinal Anesthesia Induced Hypotension in Elderly
Conditions: Spinal Induced Hypotension; Elderly
Conditions: Spinal Induced Hypotension; Elderly
December 10, 2019
13
NCT04195308
Not yet recruiting
Not yet recruiting
SAINT for Treatment of Preoperative Depression to Reduce Opioid Use Following Arthroplasty
Conditions: Treatment Resistant Depression
Conditions: Treatment Resistant Depression
December 9, 2019
14
NCT04195295
Not yet recruiting
Not yet recruiting
Regeneration of Intrabony Defects With Nano Hydroxyapatite Graft, and Periosteum as Barrier Membrane Under Magnification
Conditions: Intrabony Periodontal Defect
Conditions: Intrabony Periodontal Defect
December 10, 2019
15
NCT04195282
Not yet recruiting
Not yet recruiting
RL-1 Novel Human-derived Bio-artificial Liver Treatment in Patients of HBV Related ACLF
Conditions: Hepatitis B; Acute-On-Chronic Liver Failure
Conditions: Hepatitis B; Acute-On-Chronic Liver Failure
December 10, 2019
16
NCT04195269
Recruiting
Recruiting
Osteoarthritis of the Knee Pain Study Using a CBD and THC Sublingual Tablet
Conditions: Osteoarthritis, Knee; Pain
Conditions: Osteoarthritis, Knee; Pain
December 10, 2019
17
NCT04195256
Not yet recruiting
Not yet recruiting
Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation
Conditions: Fracture; Dislocation
Conditions: Fracture; Dislocation
December 9, 2019
18
NCT04195243
Not yet recruiting
Not yet recruiting
Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
Conditions: Type 2 Diabetes Mellitus
Conditions: Type 2 Diabetes Mellitus
December 10, 2019
19
NCT04195230
Not yet recruiting
Not yet recruiting
Cognitive Multi-Tasking Training in Healthy Older Adults
Conditions: Age-related Cognitive Decline
Conditions: Age-related Cognitive Decline
December 10, 2019
20
NCT04195217
Not yet recruiting
Not yet recruiting
" Application of Art Therapy in Oncology: Evaluation of the Symptomatic of Patients Suffering From a Cancerous Disease"
Conditions: Therapy-Associated Cancer
Conditions: Therapy-Associated Cancer
December 10, 2019
21
NCT04195204
Not yet recruiting
Not yet recruiting
The Effect of Tropisetron on Postopertative Cognitive Dysfunction in Patients Undergoing Cardiac Surgery
Conditions: Postoperative Cognitive Dysfunction; Postoperative Delirium
Conditions: Postoperative Cognitive Dysfunction; Postoperative Delirium
December 10, 2019
22
NCT04195191
Recruiting
Recruiting
Intervention to Improve the Adherence in Community Pharmacies
Conditions: Chronic Obstructive Pulmonary Disease (COPD; Arterial Hypertension; Diabetes Mellitus
Conditions: Chronic Obstructive Pulmonary Disease (COPD; Arterial Hypertension; Diabetes Mellitus
December 10, 2019
23
NCT04195178
Not yet recruiting
Not yet recruiting
Understanding the Cognition and Decision Making of Community Anesthesiologists
Conditions: Neuromuscular Blockade
Conditions: Neuromuscular Blockade
December 9, 2019
24
NCT04195165
Recruiting
Recruiting
The Effect of Sitting and Moderate Exercise on Plasma Insulin and Glucose Responses to an Oral Glucose Tolerance Test
Conditions: Sedentary Behavior; Insulin Sensitivity; Sedentary Lifestyle
Conditions: Sedentary Behavior; Insulin Sensitivity; Sedentary Lifestyle
December 9, 2019
25
NCT04195152
Active, not recruiting
Active, not recruiting
Lingual Nerve Injury in Patients With Difficult Intubation
Conditions: Difficult Intubation; Lingual Nerve Injuries
Conditions: Difficult Intubation; Lingual Nerve Injuries
December 10, 2019
26
NCT04195139
Recruiting
Recruiting
Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM
Conditions: Glioblastoma Multiforme
Conditions: Glioblastoma Multiforme
December 9, 2019
27
NCT04195126
Not yet recruiting
Not yet recruiting
Early Haemadsorption in Major Burns
Conditions: Burns; Multiple Organ Failure; Shock; Organ Dysfunction Syndrome, Multiple; Renal Dysfunction; Cytokine Storm
Conditions: Burns; Multiple Organ Failure; Shock; Organ Dysfunction Syndrome, Multiple; Renal Dysfunction; Cytokine Storm
December 9, 2019
28
NCT04195113
Recruiting
Recruiting
Perioperative Anticoagulant Use for Surgery Evaluation Emergency Registry
Conditions: Atrial Fibrillation; Venous Thromboembolism; Arterial Vascular Disease
Conditions: Atrial Fibrillation; Venous Thromboembolism; Arterial Vascular Disease
December 9, 2019
29
NCT04195100
Recruiting
Recruiting
Local Pilocarpine for Relieving Dry Mouth
Conditions: Patients of Advanced Age (≥ 70 Years) With a Clinical Diagnosis of Chronic Dry Mouth
Conditions: Patients of Advanced Age (≥ 70 Years) With a Clinical Diagnosis of Chronic Dry Mouth
December 9, 2019
30
NCT04195087
Recruiting
Recruiting
Perfusion Index and Pleth Variability Index in Cesarean Section.
Conditions: Cesarean Section Complications
Conditions: Cesarean Section Complications
December 9, 2019
31
NCT04195074
Recruiting
Recruiting
Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b
Conditions: Chronic Hepatitis b
Conditions: Chronic Hepatitis b
December 9, 2019
32
NCT04195061
Not yet recruiting
Not yet recruiting
Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
Conditions: Overweight and Obesity; Insulin Resistance
Conditions: Overweight and Obesity; Insulin Resistance
December 9, 2019
33
NCT04195048
Completed
Completed
Mechanism and Outcome of Acute Ischemic Stroke in Cancer Patients
Conditions: Ischemic Stroke; Cancer
Conditions: Ischemic Stroke; Cancer
December 9, 2019
34
NCT04195035
Not yet recruiting
Not yet recruiting
Comparison of Air QTM Intubating Airway Versus Ambu-Aura Intubating Laryngeal Mask
Conditions: Airway Management; Obesity
Conditions: Airway Management; Obesity
December 7, 2019
35
NCT04195022
Recruiting
Recruiting
Comparison of a Chemically Activated Composite Resin Alkasite With Resin Composite in Atypical Caries Lesions of Deciduous Teeth
Conditions: Dental Caries in Children
Conditions: Dental Caries in Children
December 9, 2019
36
NCT04195009
Not yet recruiting
Not yet recruiting
Impact of Suppressing Surgical Stress Reaction on Postoperative Inflammation.
Conditions: Inflammation; Postoperative Pain
Conditions: Inflammation; Postoperative Pain
December 9, 2019
37
NCT04194996
Recruiting
Recruiting
Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
Conditions: Cervical Deformity
Conditions: Cervical Deformity
December 10, 2019
38
NCT04194983
Recruiting
Recruiting
The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans
Conditions: Ageing; Mitochondrial Function; Physical Function; Cognitive Function
Conditions: Ageing; Mitochondrial Function; Physical Function; Cognitive Function
December 10, 2019
39
NCT04194970
Not yet recruiting
Not yet recruiting
Monitoring of Weight Bearing Protocols Via Mobile Application and Pressure Sensors.
Conditions: Osteochondral Lesion of Talus
Conditions: Osteochondral Lesion of Talus
December 9, 2019
40
NCT04194957
Not yet recruiting
Not yet recruiting
Improving the Safety of Fluoropyrimidine-based Chemotherapy
Conditions: Neoplasms
Conditions: Neoplasms
December 9, 2019
41
NCT04194944
Not yet recruiting
Not yet recruiting
A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer
Conditions: Non-Small Cell Lung Cancer
Conditions: Non-Small Cell Lung Cancer
December 9, 2019
42
NCT04194931
Recruiting
Recruiting
Humanized CAR-T Cells of Anti-BCAM and Anti-CD19 Against Relapsed and Refractory Multiple Myeloma
Conditions: Relapsed or Refractory Multiple Myeloma
Conditions: Relapsed or Refractory Multiple Myeloma
December 10, 2019
43
NCT04194918
Not yet recruiting
Not yet recruiting
Flexiquit+: Web Program to Promote Smoking Cessation in Sexual and Gender Minority Young Adult Smokers
Conditions: Tobacco Use Disorder
Conditions: Tobacco Use Disorder
December 10, 2019
44
NCT04194905
Completed
Completed
Bioavailability of Levonorgestrel/Ethinyl Estradiol Tablets 0.1 mg/0.02 mg With Regards to Reference Product
Conditions: Bioequivalence
Intervention: Levonorgestrel 0.1 Mg And Ethinyl Estradiol 0.02 Mg Test Product, Levonorgestrel 0.1 Mg And Ethinyl Estradiol 0.02 Mg Reference Product
Conditions: Bioequivalence
Intervention: Levonorgestrel 0.1 Mg And Ethinyl Estradiol 0.02 Mg Test Product, Levonorgestrel 0.1 Mg And Ethinyl Estradiol 0.02 Mg Reference Product
December 9, 2019
45
NCT04194892
Completed
Completed
A Crossover Study to Evaluate Pegilodecakin (LY3500518) in Healthy Participants
Conditions: Healthy
Conditions: Healthy
December 10, 2019
46
NCT04194879
Not yet recruiting
Not yet recruiting
Effectiveness of Multi-target FIT-DNA Analysis as a Colorectal Cancer Screening Test
Conditions: Colorectal Cancer; Adenoma Colon
Conditions: Colorectal Cancer; Adenoma Colon
December 8, 2019
47
NCT04194866
Recruiting
Recruiting
The Effect of Circadian Clock System on Perioperative Cognitive Function of Elderly Patients
Conditions: Circadian Clock; Postoperative Cognitive Function; General Anesthesia; Elderly Patients
Conditions: Circadian Clock; Postoperative Cognitive Function; General Anesthesia; Elderly Patients
December 10, 2019
48
NCT04194853
Recruiting
Recruiting
Electromyographic Biofeedback on Performance of Vastus Medialis Oblique Muscle in Knee Osteoarthritis
Conditions: Knee Osteoarthritis
Conditions: Knee Osteoarthritis
December 10, 2019
49
NCT04194840
Not yet recruiting
Not yet recruiting
Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT
Conditions: Stem Cell Transplant Complications; Myeloma; Lymphoma; Allogeneic and Autologous Stem Cell Transplant
Conditions: Stem Cell Transplant Complications; Myeloma; Lymphoma; Allogeneic and Autologous Stem Cell Transplant
December 10, 2019
50
NCT04194827
Recruiting
Recruiting
Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring
Conditions: Rheumatoid Arthritis
Conditions: Rheumatoid Arthritis
December 10, 2019
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 … 6470 6471 6472 6473 6474 6475 6476 6477 6478 6479 6480 6481 6482 6483 6484 6485 6486 6487 6488 6489 Next Last
Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.