ICH GCP | Clinical Trials Registry

Clinical Trials



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#
NCTID/Status
Study
Last Changed
1
NCT04066049
Not yet recruiting
EMT en Español for Spanish-speaking Toddlers With Language Delays
Conditions: Language Development Disorders
Intervention: EMT En Español
August 21, 2019
2
NCT04066036
Recruiting
Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa: A Prospective Observational Cohort Study
Conditions: HIV-1-infection
Intervention: This Is An Observational Study Only.
August 21, 2019
3
NCT04066023
Not yet recruiting
Double-Blind Comparison of the Efficacy and Safety of C213 to Placebo for the Acute Treatment of Cluster Headaches
Conditions: Cluster Headache
Intervention: C213 Microneedle System, Placebo
August 21, 2019
4
NCT04066010
Completed
Optimizing the Approach of Mobile Application Use to Improve Medication Adherence in Patients With Hypertension
Conditions: Medication Adherence; Hypertension
Intervention: Mobile Application (BP-n-Me)
August 21, 2019
5
NCT04065997
Not yet recruiting
Apogee International
Conditions: Chronic Heart Failure
Intervention: HeartWare Ventricular Assist Device
August 21, 2019
6
NCT04065984
Recruiting
Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES)
Conditions: Rectal Cancer; Colorectal Cancer; Colon Cancer; Colo-rectal Cancer; Sarcopenia; Sarcopenic Obesity; Advanced Cancer; Recurrent Rectal Cancer
Intervention: Microstim 2v2 Stimulator
August 21, 2019
7
NCT04065971
Not yet recruiting
Randomized, Placebo-controlled, Double-blind Study of 2LHERP® in Orofacial Herpes Infections.
Conditions: Herpes Simplex
Intervention: 2LHERP®, Placebo
August 21, 2019
8
NCT04065958
Not yet recruiting
Yoga-mindfulness for Chronic Arthritis Patients With Persistent Pain - a Pragmatic Randomized Controlled Trial
Conditions: Rheumatoid Arthritis; Psoriatic Arthritis; Pain
Intervention: Yoga-mindfulness, Patient Education And Physiotherapy
August 21, 2019
9
NCT04065945
Not yet recruiting
Epigenetic Safety of Assisted Reproductive Technology
Conditions: Infertility
Intervention: Completion Questionnaires/providing Biological Samples
August 21, 2019
10
NCT04065932
Not yet recruiting
A Study to Determine the Drug Level Profile of Different Formulations BMS-986165 Tablets
Conditions: Lupus
Intervention: BMS-986165-01, BMS-986165 Tablet, Famotidine
August 21, 2019
11
NCT04065919
Not yet recruiting
Evaluation of Liposomal Bupivacaine Compared to Usual Care and Its Effects on Pain for Cardiac Surgery
Conditions: Cardiothoracic Surgery
Intervention: Liposomal Bupivacaine, 0.25% Bupivacaine With Epinephrine
August 21, 2019
12
NCT04065906
Recruiting
Near-infrared Spectroscopy Neurofeedback as a Treatment for Children With Attention Deficit Hyperactivity Disorder
Conditions: Neurofeedback; Attention Deficit Hyperactivity Disorder (ADHD)
Intervention: NIRS Neurofeedback, Methylphenidate Or Tomoxetine
August 20, 2019
13
NCT04065893
Not yet recruiting
Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
Conditions: Systolic Heart Failure; Ventricular Premature Complexes; Ventricular Tachycardia; Cardiac Resynchronization Therapy; Reduced Biventricular Pacing
Intervention: Catheter Ablation Of Ventricular Arrhythmia, Intensified Medical Therapy
August 21, 2019
14
NCT04065880
Not yet recruiting
Neoveil® Versus TachoSil® for the Treatment of Pulmonary Air Leaks Following Lung Operation
Conditions: Prolonged Air Leak; Postoperative Air Leak
Intervention: TachoSil®, Neoveil®
August 20, 2019
15
NCT04065867
Recruiting
Use ICT to Promote Family Well-being in Hong Kong
Conditions: Family Relations
Intervention: ICT Activities
August 21, 2019
16
NCT04065854
Recruiting
Promoting Activity, Independence and Stability in Early Dementia and Mild Cognitive Impairment
Conditions: Dementia; Mild Cognitive Impairment
Intervention: Intervention
August 20, 2019
17
NCT04065841
Not yet recruiting
Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin Compared to Each Monotherapy, in Adult Patients With NASH and Liver Fibrosis.
Conditions: Non Alcoholic Steatohepatitis (NASH)
Intervention: Tropifexor, Licogliflozin
August 20, 2019
18
NCT04065828
Completed
Oral Status and Care Needs of People Aged 90 and Over
Conditions: Oral Health; Morbidity
August 21, 2019
19
NCT04065815
Recruiting
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
Conditions: Cancer; Cancer Cachexia; Inflammation
Intervention: Resistance Training, WB-EMS, High-intensity Interval Training (HIIT), Combined HIIT And Resistance Training (Combi)
August 21, 2019
20
NCT04065802
Not yet recruiting
Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia Management
Conditions: Stereotactic Radioablation for Ventricular Tachycardia
Intervention: Stereotactic Radioablation
August 20, 2019
21
NCT04065789
Recruiting
Carfilzomib in Combination With Daratumumab, Lenalidomide and Dexamethasone in Transplant-ineligible NDMM Patients
Conditions: Myeloma Multiple; Myeloma, Plasma-Cell; Myeloma-Multiple; Plasma Cell Myeloma
Intervention: Carfilzomib, Daratumumab, Lenalidomide, Dexamethasone
August 21, 2019
22
NCT04065776
Not yet recruiting
A Phase II Study of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma
Conditions: Glioma; Pilocytic Astrocytoma; Pilomyxoid Astrocytoma; Pleomorphic Xanthoastrocytoma; Ganglioglioma; Optic Pathway Glioma; Diffuse Astrocytoma
Intervention: C-11 Methionine
August 20, 2019
23
NCT04065763
Not yet recruiting
Effect of the Dural Sac Dimension on the Spread of Spinal Anesthesia
Conditions: Elderly Patients
Intervention: Ultrasound Assessment Of Dural Sac Dimension
August 21, 2019
24
NCT04065750
Not yet recruiting
Exposure to Antibiotics and Incidence of Bacteraemia Caused by Resistant Bacteria
Conditions: Bacteremia
August 21, 2019
25
NCT04065737
Not yet recruiting
Sintilimab to Prevent High-risk Oral Premalignant Lesions Cancerization
Conditions: Oral Cavity Cancer; Mouth Neoplasm; Precancerous Conditions
Intervention: Sintilimab
August 21, 2019
26
NCT04065724
Completed
Exercise for People With Peripheral Neuropathy and Diabetic Foot Ulcers - a Case Series on Feasibility and Safety
Conditions: Diabetes Mellitus; Foot Ulcer
Intervention: Physical Training As Resistance And Aerobic Training.
August 21, 2019
27
NCT04065711
Recruiting
Multi-Center Study of the Soliton Rapid Acoustic Pulse (RAP) Device for the Treatment of Cellulite
Conditions: Cellulite
Intervention: Soliton's Rapid Acoustic Pulse (RAP)
August 20, 2019
28
NCT04065698
Recruiting
Pharmacokinetics and Safety of RV521 Formulations
Conditions: Respiratory Syncytial Virus Infections
Intervention: RV521
August 21, 2019
29
NCT04065685
Not yet recruiting
A Nurse-led Patient-centred Intervention to Increase Written Advance Care Planning
Conditions: Advance Care Planning; Outpatients; Palliative Care
Intervention: Serious Game Named Go Wish, Usual Care
August 21, 2019
30
NCT04065672
Not yet recruiting
Low-dose IL-2 Treatment on Behcet's Disease
Conditions: Behcet's Disease
Intervention: Low-dose IL-2
August 21, 2019
31
NCT04065659
Withheld
[Trial of device that is not approved or cleared by the U.S. FDA]
Conditions: 
August 20, 2019
32
NCT04065646
Completed
Nutrition Education and e-Texting to Increase Access to Fresh Produce
Conditions: Healthy Eating
Intervention: Mobile
August 21, 2019
33
NCT04065633
Recruiting
Study of Commercial and Phase 3 of PF-04965842 Formulations, Estimation of Effect of Food on Commercial Formulation
Conditions: Dermatitis, Atopic
Intervention: P3-Fast, Comm-Fast, Vari-Fast, Comm-Fed
August 20, 2019
34
NCT04065620
Not yet recruiting
Ambulatory Blood Pressure in HFPEF Outcomes Global Registry
Conditions: Heart Failure With Preserved Ejection Fraction; Arterial Hypertension; Frailty Syndrome; Comorbidities and Coexisting Conditions
Intervention: Ambulatory Blood Pressure Measurement
August 21, 2019
35
NCT04065607
Completed
Indications and Outcome of Laparostomy
Conditions: Laparotomy
Intervention: Reopen The Abdomen To Check Missed Pathology Or Abdominal Washouts
August 20, 2019
36
NCT04065594
Completed
Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness
Conditions: Ulcer Foot; Chronic Skin Ulcer; Non-Healing Ulcer of Skin
Intervention: PRP Dressing, Conventional Ordinary Dressing
August 21, 2019
37
NCT04065581
Not yet recruiting
Bioequivalence Study for Acarbose/Metformin FDC
Conditions: Diabetes Mellitus, Type 2
Intervention: Acarbose/Metformin FDC(BAY81-9783), Glucobay, Glucophage
August 21, 2019
38
NCT04065568
Recruiting
An Interactive Distance Solution for Stroke Rehabilitation in the Home Setting
Conditions: Stroke Rehabilitation
Intervention: DISKO-tool
August 20, 2019
39
NCT04065555
Not yet recruiting
Intratumoral Microdosing of TAK-981 in Head and Neck Cancer
Conditions: Head and Neck Cancer
Intervention: TAK-981
August 20, 2019
40
NCT04065542
Recruiting
Determinants of Health and Cancer: Investigating the Conceptions of Children From 6 to 11 Years Old
Conditions: Child; Determinants of Health; Qualitative Research; Cancer
August 21, 2019
41
NCT04065529
Not yet recruiting
Double Blind, Randomized, Controlled With Placebo Clinical Trial in Children Between 3 Months and 14 Years Old to Evaluate the Efficacy and Safety of Gelatin Tannate in the Treatment of Acute Diarrhea (INDIGO)
Conditions: Diarrhea
Intervention: Gelatin Tannate (GT) + Oral Rehydration Solution (ORS) + Zinc Supplementation, Placebo + ORS + Zinc Supplementation
August 21, 2019
42
NCT04065516
Enrolling by invitation
ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia
Conditions: Achalasia; Gastroesophageal Reflux
Intervention: ARAT Technique
August 20, 2019
43
NCT04065503
Not yet recruiting
Probiotic Detection and Persistence Study
Conditions: Healthy
Intervention: Probiotic Strains
August 21, 2019
44
NCT04065490
Not yet recruiting
Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III)
Conditions: Dry Age-related Macular Degeneration
Intervention: Valeda PBM Treatment, Valeda Sham Treatment
August 20, 2019
45
NCT04065477
Not yet recruiting
Improving Time-Based Prospective Memory in TBI
Conditions: Traumatic Brain Injury
Intervention: Computer-based Cognitive Rehabilitation (CBCR)
August 20, 2019
46
NCT04065464
Recruiting
TRACY - Track My Cycle
Conditions: Fertility Monitor; Cycle Tracking
Intervention: Ava Fertility Tracker
August 20, 2019
47
NCT04065451
Not yet recruiting
Effect of Epinephrine on Post-polypectomy Pain
Conditions: Colonic Polyp
Intervention: Epinephrine
August 20, 2019
48
NCT04065438
Not yet recruiting
Post Approval Study for Treatment of Drug-resistant Adult Primary FSGS Using the LIPOSORBER® LA-15 System
Conditions: Focal Segmental Glomerulosclerosis
Intervention: LIPOSORBER® LA-15
August 20, 2019
49
NCT04065425
Not yet recruiting
Phase I/II Assessment of Immuno-Oncology Drugs Elotuzumab, Anti-LAG-3 and Anti-TIGIT
Conditions: Multiple Myeloma; Relapsed Refractory Multiple Myeloma
Intervention: Elotuzumab, Pomalidomide, Dexamethasone, Anti-LAG-3 Monoclonal Antibody BMS-986016, Pomalidomide, Dexamethasone, Anti-TIGIT Monoclonal Antibody BMS-986207, Pomalidomide, Dexamethasone
August 21, 2019
50
NCT04065412
Not yet recruiting
Modified Laryngeal Handshake Technique
Conditions: Airway Complication of Anesthesia
Intervention: Conventional Laryngeal Handshake Technique, Modified Laryngeal Handshake Technique
August 21, 2019

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

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