ICH GCP | Clinical Trials Registry

Clinical Trials



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#
NCTID/Status
Study
Last Changed
1
NCT04027335
Not yet recruiting
Use of the Leva Pelvic Digital Health System in Women With Fecal Incontinence: a Pilot Study
Conditions: Fecal Incontinence
Intervention: Leva
July 18, 2019
2
NCT04027322
Recruiting
Inhaled Steroids for Acute Pharyngitis.
Conditions: Acute Pharyngitis
Intervention: Budesonide 0.25 MG/ML Inhalant Solution, Dexamethasone, Normal Saline
July 18, 2019
3
NCT04027309
Not yet recruiting
A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy
Conditions: Acute Myeloid Leukemia; Myelodysplastic Syndrome With Excess Blasts-2
Intervention: Gilteritinib, Midostaurin
July 18, 2019
4
NCT04027296
Not yet recruiting
Development and Validation of the GLORI-COPD Score
Conditions: Pulmonary Disease, Chronic Obstructive
July 18, 2019
5
NCT04027283
Not yet recruiting
Acute Effects of the Two Alternative Sweeteners D-allulose and Erythritol on Metabolism
Conditions: Physiological Satiation Mechanisms
Intervention: Erythritol, Erythritol + Lactisole, D-allulose, D-allulose + Lactisole, Tap Water, Tap Water + Lactisole
July 17, 2019
6
NCT04027270
Not yet recruiting
Pelvic Health and Physical Therapy to Improve Lives of Prostate Cancer Patients Undergoing Prostatectomy
Conditions: Prostate Cancer
Intervention: Physical Therapy
July 18, 2019
7
NCT04027257
Not yet recruiting
Sit Together and Read (STAR): A Pilot Study of Children and Their Kinship Caregivers
Conditions: Reading
Intervention: Sit Together And Read (STAR)
July 18, 2019
8
NCT04027244
Recruiting
Leg Ischaemia Management Collaboration
Conditions: Peripheral Arterial Disease; Critical Limb Ischemia; Frailty; Cognitive Impairment; Coronary Artery Disease
July 18, 2019
9
NCT04027231
Not yet recruiting
Electrochemical Behavior of Biomedical Alloys Exposed to Human Synovial Fluid
Conditions: Arthroplasty, Replacement, Knee; Osteoarthritis, Knee
Intervention: Analysis Of The Synovial Fluid
July 18, 2019
10
NCT04027218
Completed
Clinical Trial to Assess the Effectiveness of Applying Dry Local Heat and/ or High Tourniquet Pressure for Venipuncture.
Conditions: Venipuncture; Healthy Adult
Intervention: Dry Heat, High Pressure, Combination Of Dry Heat And High Pressure
July 18, 2019
11
NCT04027205
Not yet recruiting
Surgery Versus PhysiothErapist-leD Exercise for Traumatic Tears of the Rotator Cuff
Conditions: Traumatic Rotator Cuff Tear
Intervention: Physiotherapist-led Exercise, Surgical Repair
July 18, 2019
12
NCT04027192
Not yet recruiting
Study to Test the Safety of Increasing Multiple Doses of BAY2328065 Given by Mouth, How the Drug is Tolerated and Acts in the Human Body of Healthy Male Participants. Alteration of the Study Drug Effects by Another Drug and the Availability of the Drug Given in Different Formulations is Also Tested.
Conditions: Endometriosis
Intervention: BAY2328065 LSF, BAY2328065 Tablet, Placebo LSF, Placebo Tablet, Midazolam
July 18, 2019
13
NCT04027179
Not yet recruiting
Tongue Dysbiosis Effects on Arterial Pressure of Periodontitis Patients
Conditions: Periodontitis; Normal Blood Pressure
Intervention: 0.12% Chlorhexidine Digluconate Mouthwash, Periodontal Instrumentation, Placebo Mouthwash
July 18, 2019
14
NCT04027166
Recruiting
Cognitive Function and Pain Threshold in People Who Are Methadone Maintained
Conditions: Pain
Intervention: Methadone, Methadone
July 16, 2019
15
NCT04027153
Not yet recruiting
The Deliver Health Study
Conditions: HIV/AIDS
Intervention: Fee Based Delivery
July 16, 2019
16
NCT04027140
Not yet recruiting
MDR - M/L Taper With Kinectiv Technology Stems and Necks
Conditions: Hip Disease; Hip Fractures; Hip Injuries; Hip Arthritis; Hip Pain Chronic
Intervention: M/L Taper With Kinectiv Technology Stems And Necks
July 18, 2019
17
NCT04027127
Completed
The Role of Netrin -1 in Acute Coronary Syndrome
Conditions: Acute Coronary Syndrome
Intervention: Netrin-1 Value On Admission To Hospital
July 18, 2019
18
NCT04027114
Enrolling by invitation
Individualized Physiotherapy and Activity Coaching for Multiple Sclerosis
Conditions: Multiple Sclerosis
Intervention: Individualized Behavioural Physical Activity Intervention
July 16, 2019
19
NCT04027101
Not yet recruiting
BAriCitinib Healing Effect in earLy pOlymyalgia Rheumatica
Conditions: Polymyalgia Rheumatic (PMR)
Intervention: Baricitinib, Placebos
July 18, 2019
20
NCT04027088
Not yet recruiting
Effect of Preoperative Immunonutrition in Upper Digestive Tract
Conditions: Immunonutrition; Gastric Cancer; Esophageal Cancer; Pancreas Cancer; Surgery--Complications
Intervention: Immunonutrition, Standard
July 18, 2019
21
NCT04027075
Not yet recruiting
Mindfulness Mobile App to Reduce Adolescent Substance Use
Conditions: Adolescent Drinking; Adolescent Problem Behavior
Intervention: Rewire App Users
July 18, 2019
22
NCT04027062
Not yet recruiting
Impact of Diabetes Continuing Education on Primary Health Care Physicians' Knowledge, Attitudes and Practice
Conditions: Diabete Mellitus
Intervention: Diabetes Continuing Education Intervention
July 18, 2019
23
NCT04027049
Recruiting
Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage
Conditions: Intra Cerebral Hemorrhage; Stroke Hemorrhagic
Intervention: Supine Cycle Ergometry Of The Lower Extremities
July 18, 2019
24
NCT04027036
Not yet recruiting
Comparison of Immunogenicity of Inactivated Poliovirus Vaccine (IPV) Administered Intramuscularly or Intradermally
Conditions: Polio
Intervention: Inactivated Poliovirus Vaccine In Reduced Doses
July 18, 2019
25
NCT04027023
Not yet recruiting
Pilot Study for Evaluation of the Impact of Intensive Short-Term Drug Therapy on Beta-Cell Function and Insulin Resistance in Patients With Type 2 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 2
Intervention: Diabetes Mellitus Type 2 De-escalation Treatment (DET)
July 18, 2019
26
NCT04027010
Recruiting
A Randomized Controlled Trial of Virtual Student Health Center Among Incarcerated Juvenile Offenders
Conditions: Lack of Knowledge About Condoms and Birth Control; Adolescent Sexual Intercourse; Sexual Intercourse Without a Condom or Birth Control; Unplanned Pregnancies
Intervention: "Healthy U" Tablet Application
July 17, 2019
27
NCT04026997
Not yet recruiting
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Dose Response of Oral CIN-102 in Adults With Diabetic Gastroparesis
Conditions: Diabetic Gastroparesis
Intervention: CIN-102, Placebos
July 18, 2019
28
NCT04026984
Not yet recruiting
Study to Evaluate Safety and Efficacy of Rifamycin SV MMX in the Treatment of Traveler's Diarrhea in Children Age 6 to 11 Years
Conditions: Traveler's Diarrhea
Intervention: Placebo, Rifamycin SV-MMX
July 18, 2019
29
NCT04026971
Completed
The Effect of Phone Application Supported Nutrition Education on Weight Loss
Conditions: Obesity
Intervention: This Study Is A Randomized Controlled Study Aiming To Evaluate The Effect Of Phone Application Supported Nutrition Education On Weight Loss According To Standard Education.
July 18, 2019
30
NCT04026958
Not yet recruiting
Clarithromycin Mechanisms in Hypersomnia Syndromes
Conditions: Narcolepsy Without Cataplexy; Idiopathic Hypersomnia
Intervention: Clarithromycin, Placebo
July 18, 2019
31
NCT04026945
Not yet recruiting
Sustained Release Lidocaine for Treatment of Scrotal Pain
Conditions: Chronic Pain
Intervention: Lidocaine
July 17, 2019
32
NCT04026932
Not yet recruiting
The Clinical Effects of Modified TRS Treatment
Conditions: Tinnitus, Subjective
Intervention: Listening To Unmodified Music, Listening To Modified Tinnitus Relieving Sound
July 18, 2019
33
NCT04026919
Recruiting
Online Support Program for Dementia Caregivers
Conditions: Effect Increased
Intervention: OK EN CASA-ZAINDOO
July 18, 2019
34
NCT04026906
Not yet recruiting
Skin Glue to Reduce Intravenous Catheter Failure in Children
Conditions: Dislodged Catheter
Intervention: Cyanoacrylate Glue, Transparent Polyurethane Dressing
July 18, 2019
35
NCT04026893
Not yet recruiting
Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)
Conditions: Infertility of Uterine Origin
Intervention: Uterine Transplant From Deceased Donor
July 18, 2019
36
NCT04026880
Not yet recruiting
Testosterone Effects on Pelvic Floor Muscles
Conditions: Urinary Incontinence; Menopause
Intervention: Testosterone Enanthate, Placebo
July 18, 2019
37
NCT04026867
Not yet recruiting
The DETECT HCV Linkage to Care Trial
Conditions: Hepatitis C
Intervention: Linkage Navigation, Clinician Referral
July 18, 2019
38
NCT04026854
Completed
Determinants of the Quality of Work Life of Psychiatric Nurses and Relief on the Quality of Care
Conditions: Quality of Work Life of Psychiatric Nurses and Impact on the Quality of Care
Intervention: Quality Of Live At Work
July 17, 2019
39
NCT04026841
Not yet recruiting
The Efficacy of PD-1 Antibody Sulituzumab on Early-stage Multiple Primary Lung Cancer With Ground Glass Density.
Conditions: Multiple Primary Lung Cancers
Intervention: PD-1 Antibody Sulituzumab
July 18, 2019
40
NCT04026828
Not yet recruiting
Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods
Conditions: Generalized Aggressive Periodontitis; Chronic Periodontitis
Intervention: Periodontitis Group
July 17, 2019
41
NCT04026815
Recruiting
Health Status and Its Socio-economic Covariates of the Older Population in Poland - the Nationwide PolSenior2 Survey.
Conditions: Aging Disorder; Age Problem; Healthy Aging; Immunity Disorders; Frailty Syndrome; Behaviors, Health; Health Care Utilization
Intervention: Medical History, Blood And Urine Tests
July 17, 2019
42
NCT04026802
Not yet recruiting
Safety and Feasibility of a Novel In--Bed Resistance Training Device in Elderly Inpatients
Conditions: Old Age; Debility
Intervention: In-Bed Resistance Training Device, Standard Of Care
July 17, 2019
43
NCT04026789
Not yet recruiting
Medication Abortion for Pregnancy of Unknown Location
Conditions: Pregnancy Related
Intervention: Same-day-start, Delay-for-diagnosis
July 17, 2019
44
NCT04026776
Not yet recruiting
Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
Conditions: Salt; Excess; Blood Pressure Disorders
Intervention: Allopurinol, Dietary Intervention
July 17, 2019
45
NCT04026763
Recruiting
MR/TRUS Fusion Guided Prostate Biopsy
Conditions: Prostate Disease; Elevated Prostate Specific Antigen; Family History of Prostate Cancer; Positive Digital Rectal Exam
Intervention: Prostate Biopsy, MR US Fusion Guided Prostate Biopsy, MR/TRUS Fusion Guided Prostate Biopsy
July 18, 2019
46
NCT04026750
Recruiting
Insulin Tolerance Test Study to Assess Safety, Tolerability and Pharmacodynamics of Pitolisant in Patients With Type 1 Diabetes
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Pitolisant
July 17, 2019
47
NCT04026737
Recruiting
Cardiovascular Effects of CART Cell Therapy
Conditions: Leukemia; Lymphoma; Cardiotoxicity; Risk Factor, Cardiovascular; Immunotherapy
July 17, 2019
48
NCT04026724
Not yet recruiting
Retrospective Cohort Study on Adjuvant Treatment of Coronary Heart Disease Angina Pectoris With Chinese Patent Medicine
Conditions: Atherosclerotic Heart Disease With Angina Nos
Intervention: Chinese Patent Medicine
July 18, 2019
49
NCT04026711
Not yet recruiting
MitoQ for the Treatment of Metabolic Dysfunction in Asthma
Conditions: Asthma; Obesity
Intervention: Mitoquinol, Placebo Oral Tablet
July 17, 2019
50
NCT04026698
Recruiting
Implementing an Intervention to Foster Resident and Family Engagement in Care Planning
Conditions: Quality of Life
Intervention: Resident And Family Engagement Intervention
July 17, 2019

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

Alphabetic (A-Z)
By Category

Dietary
Supplements

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