Clinical Trials
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NCTID/Status
Study
Last Changed
1
NCT04061525
Recruiting
Recruiting
Motion and IntraCoronary Ecg Ischemia Development Study (MICE)
Conditions: Ischaemic Heart Disease
Intervention: Percutaneous Coronary Intervention With FFR Measurement And Intracoronary ECG Registration
Conditions: Ischaemic Heart Disease
Intervention: Percutaneous Coronary Intervention With FFR Measurement And Intracoronary ECG Registration
August 16, 2019
2
NCT04061512
Not yet recruiting
Not yet recruiting
Rituximab and Ibrutinib (RI) Versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as Initial Therapy for Waldenström's Macroglobulinaemia
Conditions: Waldenstrom Macroglobulinemia
Intervention: Dexamethasone, Cyclophosphamide, Rituximab, Rituximab, Ibrutinib
Conditions: Waldenstrom Macroglobulinemia
Intervention: Dexamethasone, Cyclophosphamide, Rituximab, Rituximab, Ibrutinib
August 16, 2019
3
NCT04061499
Not yet recruiting
Not yet recruiting
Ultrasound and CT to Measure Muscle in Hip OA
Conditions: Hip Osteoarthritis
Conditions: Hip Osteoarthritis
August 16, 2019
4
NCT04061486
Recruiting
Recruiting
Sperm Separation Efficiency to Maximize Pregnancy Rates: MACS vs. FERTILE Chip
Conditions: Infertility, Male
Conditions: Infertility, Male
August 16, 2019
5
NCT04061473
Recruiting
Recruiting
1 Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion
Conditions: Diabetes After Total Pancreatectomy
Intervention: Sitagliptin 100mg, Empagliflozin 25 MG, Placebo Tablet
Conditions: Diabetes After Total Pancreatectomy
Intervention: Sitagliptin 100mg, Empagliflozin 25 MG, Placebo Tablet
August 16, 2019
6
NCT04061460
Completed
Completed
Periodontal Treatment in Non Smokers, Former Smokers and Smokers
Conditions: Periodontitis
Intervention: Mechanical Plaque Control
Conditions: Periodontitis
Intervention: Mechanical Plaque Control
August 16, 2019
7
NCT04061447
Completed
Completed
Tailored Juice-guided Eradication Therapy, Randomized Controlled Trial
Conditions: Helicobacter Pylori Infection
Intervention: Susceptibility-guided Therapy, Empirical Clarithromycin-based Triple Therapy
Conditions: Helicobacter Pylori Infection
Intervention: Susceptibility-guided Therapy, Empirical Clarithromycin-based Triple Therapy
August 16, 2019
8
NCT04061434
Recruiting
Recruiting
ECG Algorithms for CRT Response Evaluation
Conditions: ECG Monitoring
Conditions: ECG Monitoring
August 15, 2019
9
NCT04061421
Not yet recruiting
Not yet recruiting
A Basket Study of Novel Therapy for Untreated MDS/MPN and Relapsed/Refractory Overlap Syndromes (ABNL-MARRO)
Conditions: MDS/MPN
Intervention: INCB053914, ASTX727, Itacitinib, INCB059872
Conditions: MDS/MPN
Intervention: INCB053914, ASTX727, Itacitinib, INCB059872
August 15, 2019
10
NCT04061408
Recruiting
Recruiting
FSRT in Breast Cancer Patients With Brain Metastases
Conditions: Breast Cancer; Brain Metastases
Intervention: Fractionated Stereotactic Radiotherapy(FSRT)
Conditions: Breast Cancer; Brain Metastases
Intervention: Fractionated Stereotactic Radiotherapy(FSRT)
August 16, 2019
11
NCT04061395
Not yet recruiting
Not yet recruiting
Guselkumab for Hidradenitis Suppurativa, a Mode of Action Study.
Conditions: Hidradenitis Suppurativa
Intervention: Guselkumab
Conditions: Hidradenitis Suppurativa
Intervention: Guselkumab
August 16, 2019
12
NCT04061382
Not yet recruiting
Not yet recruiting
Sero-epidemiological Survey of England in 2019/2020
Conditions: Serogroup C Meningococcal Meningitis; Diphtheria
Intervention: Venepuncture
Conditions: Serogroup C Meningococcal Meningitis; Diphtheria
Intervention: Venepuncture
August 16, 2019
13
NCT04061369
Recruiting
Recruiting
Energy Expenditure and Substrate Oxidation in a Whole Room Calorimeter
Conditions: Overweight; Obesity; Body Weight
Intervention: Low Fat Meal, Moderate Fat Meal, High Fat Meal, High Fat Liquid Meal
Conditions: Overweight; Obesity; Body Weight
Intervention: Low Fat Meal, Moderate Fat Meal, High Fat Meal, High Fat Liquid Meal
August 16, 2019
14
NCT04061356
Recruiting
Recruiting
Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device (Inflammacheck™) in Patients With Interstitial Lung Disease, Lung Cancer and Healthy Volunteers.
Conditions: Interstitial Lung Disease; Lung Cancer
Conditions: Interstitial Lung Disease; Lung Cancer
August 16, 2019
15
NCT04061343
Recruiting
Recruiting
The Effects of Changing Light Levels on Contrast Sensitivity in Patients With Glaucoma
Conditions: Glaucoma
Conditions: Glaucoma
August 16, 2019
16
NCT04061330
Not yet recruiting
Not yet recruiting
Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures
Conditions: Pain, Acute
Intervention: Ketamine, Morphine
Conditions: Pain, Acute
Intervention: Ketamine, Morphine
August 16, 2019
17
NCT04061317
Not yet recruiting
Not yet recruiting
SPOT-FRAILTY Assessment of Frailty in Patients Over the Age of 70 Undergoing a Cardiac Intervention
Conditions: Frailty
Intervention: Frailty Assessment
Conditions: Frailty
Intervention: Frailty Assessment
August 16, 2019
18
NCT04061304
Not yet recruiting
Not yet recruiting
A Clinical Trial Into the Efficacy of rTMS Treatment for Treating Anorexia Nervosa and Bulimia Nervosa
Conditions: Eating Disorders; Anorexia Nervosa; Bulimia Nervosa
Intervention: Repetitive Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Conditions: Eating Disorders; Anorexia Nervosa; Bulimia Nervosa
Intervention: Repetitive Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
August 15, 2019
19
NCT04061291
Completed
Completed
Study to Explore the Relationship Between the Level of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device Against Existing Measures of Lung Disease
Conditions: Asthma; COPD Exacerbation
Conditions: Asthma; COPD Exacerbation
August 16, 2019
20
NCT04061278
Recruiting
Recruiting
A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients
Conditions: Nasopharyngeal Carcinoma; Neoadjuvant Chemotherapy
Intervention: 4 Cycles Of Neoadjuvant Chemotherapy With Definitive Radiotherapy, 3 Cycles Of Neoadjuvant Chemotherapy With Concurrent Chemoradiotherapy
Conditions: Nasopharyngeal Carcinoma; Neoadjuvant Chemotherapy
Intervention: 4 Cycles Of Neoadjuvant Chemotherapy With Definitive Radiotherapy, 3 Cycles Of Neoadjuvant Chemotherapy With Concurrent Chemoradiotherapy
August 16, 2019
21
NCT04061265
Not yet recruiting
Not yet recruiting
Articaine 4% in Children Under Age of 4 Years
Conditions: Behaviour Assessment; Pain
Intervention: Articaine 4%/Epi 1:200000 Inj Cart 1.7Ml
Conditions: Behaviour Assessment; Pain
Intervention: Articaine 4%/Epi 1:200000 Inj Cart 1.7Ml
August 16, 2019
22
NCT04061252
Not yet recruiting
Not yet recruiting
A Study of KHK4827 in Subjects With Palmoplantar Pustulosis
Conditions: Palmoplantar Pustulosis
Intervention: KHK4827, Placebo
Conditions: Palmoplantar Pustulosis
Intervention: KHK4827, Placebo
August 16, 2019
23
NCT04061239
Not yet recruiting
Not yet recruiting
Comparison of Therapies Before Stem Cell Transplantation in Patients With Higher Risk MDS and Oligoblastic AML
Conditions: MDS; AML
Intervention: CPX-351, Daunorubicin, Cytarabine, Azacitidine
Conditions: MDS; AML
Intervention: CPX-351, Daunorubicin, Cytarabine, Azacitidine
August 16, 2019
24
NCT04061226
Recruiting
Recruiting
Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea
Conditions: Sleep Disorder; Body Fat Distribution
Intervention: Overnight Polysomnography
Conditions: Sleep Disorder; Body Fat Distribution
Intervention: Overnight Polysomnography
August 16, 2019
25
NCT04061213
Recruiting
Recruiting
ATTR Amyloidosis in Elderly Patients With Aortic Stenosis
Conditions: Aortic Stenosis Symptomatic; Amyloidosis Cardiac
Intervention: Tc-99m-DPD Scintigraphy
Conditions: Aortic Stenosis Symptomatic; Amyloidosis Cardiac
Intervention: Tc-99m-DPD Scintigraphy
August 15, 2019
26
NCT04061200
Not yet recruiting
Not yet recruiting
Renal Effects of Treatment With Empagliflozin Alone or in Combination With Semaglutide in Patients With Type 2 Diabetes and Albuminuria
Conditions: Type 2 Diabetes With Renal Manifestations
Intervention: Semaglutide, 1.34 Mg/mL, Placebo, 1,34 Mg/mL, Empagliflozin 25 MG
Conditions: Type 2 Diabetes With Renal Manifestations
Intervention: Semaglutide, 1.34 Mg/mL, Placebo, 1,34 Mg/mL, Empagliflozin 25 MG
August 16, 2019
27
NCT04061187
Enrolling by invitation
Enrolling by invitation
Livestreaming From Smartphones as a Supplement to Emergency Calls
Conditions: Out-Of-Hospital Cardiac Arrest; Emergencies; Unconscious
Conditions: Out-Of-Hospital Cardiac Arrest; Emergencies; Unconscious
August 16, 2019
28
NCT04061174
Not yet recruiting
Not yet recruiting
Effects of Shoulder Stabilization Exercises in the Office Workers With Shoulder Protraction
Conditions: Work-Related Condition
Intervention: Shoulder Stabilization Exercises, Office Exercises Training
Conditions: Work-Related Condition
Intervention: Shoulder Stabilization Exercises, Office Exercises Training
August 16, 2019
29
NCT04061161
Not yet recruiting
Not yet recruiting
Anti-inflammatory Effects of Tiotropium in Patients With Stable COPD
Conditions: COPD
Intervention: Tiotropium Bromide
Conditions: COPD
Intervention: Tiotropium Bromide
August 16, 2019
30
NCT04061148
Recruiting
Recruiting
Near Infrared Spectroscopy (NIRS) for Assessment of Depression
Conditions: Major Depressive Disorder
Intervention: NIRSIT
Conditions: Major Depressive Disorder
Intervention: NIRSIT
August 15, 2019
31
NCT04061135
Not yet recruiting
Not yet recruiting
Response Inhibition and Deep Brain Stimulation in Parkinson's Disease
Conditions: Parkinson Disease
Intervention: Response Inhibition And Deep Brain Stimulation In Parkinson's Disease
Conditions: Parkinson Disease
Intervention: Response Inhibition And Deep Brain Stimulation In Parkinson's Disease
August 15, 2019
32
NCT04061122
Recruiting
Recruiting
The Role of Congenital Mucosal Immune System in the Airways of Patients With Chronic Obstructive Pulmonary Disease
Conditions: COPD Exacerbation; Smoking, Tobacco
Intervention: Airway Epithelial Smear Test
Conditions: COPD Exacerbation; Smoking, Tobacco
Intervention: Airway Epithelial Smear Test
August 16, 2019
33
NCT04061109
Recruiting
Recruiting
Safety, Efficacy Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A.
Conditions: Hemophilia A
Intervention: Recombinant Human Coagulation FVIII
Conditions: Hemophilia A
Intervention: Recombinant Human Coagulation FVIII
August 16, 2019
34
NCT04061096
Completed
Completed
Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization
Conditions: Molar Incisor Hypomineralization
Intervention: Evaluation Of Cold Test, Evaluation Of Electrical Pulp Test, Evaluation Of Pain During The Treatment
Conditions: Molar Incisor Hypomineralization
Intervention: Evaluation Of Cold Test, Evaluation Of Electrical Pulp Test, Evaluation Of Pain During The Treatment
August 16, 2019
35
NCT04061083
Recruiting
Recruiting
Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents
Conditions: Mechanical Ventilation Complication; Ventilator Associated Pneumonia; Nursing Caries; Aspiration, Respiratory
Intervention: Smart Cuff Manager, Manometer
Conditions: Mechanical Ventilation Complication; Ventilator Associated Pneumonia; Nursing Caries; Aspiration, Respiratory
Intervention: Smart Cuff Manager, Manometer
August 16, 2019
36
NCT04061070
Not yet recruiting
Not yet recruiting
Effects of Trehalose and Polyphenols in Vasculopathic Patients
Conditions: Oxidative Stress; Cardiovascular Diseases
Intervention: Supplementation With Mix Of Threalose Plus Polyphenols, No Supplementation With Mix Of Threalose Plus Polyphenols
Conditions: Oxidative Stress; Cardiovascular Diseases
Intervention: Supplementation With Mix Of Threalose Plus Polyphenols, No Supplementation With Mix Of Threalose Plus Polyphenols
August 16, 2019
37
NCT04061057
Completed
Completed
Effect of Perioperative Intravenous Lidocaine Infusion on Postoperative Recovery in Patients Undergoing Arthroscopic Rotator Cuff Repair Under General Anesthesia
Conditions: Rotator Cuff Tears
Intervention: Lidocaine, Normal Saline
Conditions: Rotator Cuff Tears
Intervention: Lidocaine, Normal Saline
August 16, 2019
38
NCT04061044
Active, not recruiting
Active, not recruiting
A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert
Conditions: Open Angle Glaucoma and Ocular Hypertension
Intervention: Ophthalmic Insert
Conditions: Open Angle Glaucoma and Ocular Hypertension
Intervention: Ophthalmic Insert
August 15, 2019
39
NCT04061031
Not yet recruiting
Not yet recruiting
Improving Self-Regulation Among Adopted Children
Conditions: Self-regulation
Intervention: Parent-Child Interaction Therapy (PCIT), Child-Centered Therapy With Parent Education
Conditions: Self-regulation
Intervention: Parent-Child Interaction Therapy (PCIT), Child-Centered Therapy With Parent Education
August 16, 2019
40
NCT04061018
Enrolling by invitation
Enrolling by invitation
The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux
Conditions: Lipid Metabolism Disorders
Conditions: Lipid Metabolism Disorders
August 14, 2019
41
NCT04061005
Not yet recruiting
Not yet recruiting
A Comparison of the Resection Rate for Cold and Hot Snare Polypectomy for 5-15 mm Colorectal Polyps
Conditions: Adenomatous Polyps
Intervention: Cold Snare Polypectomy, Hot Snare Polypectomy, Endoscopic Margin Observation Method
Conditions: Adenomatous Polyps
Intervention: Cold Snare Polypectomy, Hot Snare Polypectomy, Endoscopic Margin Observation Method
August 15, 2019
42
NCT04060992
Not yet recruiting
Not yet recruiting
Hormonal Effects of the Oral Gonadotropin Releasing Hormone (GnRH) Antagonist at Different Periods of the Menstrual Cycle
Conditions: Ovulation; Failure or Lack of
Intervention: Elagolix 200 MG Oral Tablet [Orilissa]
Conditions: Ovulation; Failure or Lack of
Intervention: Elagolix 200 MG Oral Tablet [Orilissa]
August 14, 2019
43
NCT04060979
Not yet recruiting
Not yet recruiting
Evaluation of Two Doses of Nitric Oxide (NO) Given Intermittently Via Inhalation to Subjects With Bronchiolitis
Conditions: Bronchiolitis Acute
Intervention: Nitric Oxide, Standard Supportive Treatment
Conditions: Bronchiolitis Acute
Intervention: Nitric Oxide, Standard Supportive Treatment
August 15, 2019
44
NCT04060966
Not yet recruiting
Not yet recruiting
Neural Mechanisms of Cost and Benefit Integration During Decision-Making, Aim 2: Acute & Lifetime Stress
Conditions: Healthy
Intervention: Cold Pressor Task
Conditions: Healthy
Intervention: Cold Pressor Task
August 16, 2019
45
NCT04060953
Not yet recruiting
Not yet recruiting
Quality of Life in Managing Chronic Pain
Conditions: Chronic Low Back Pain
Intervention: Health-Related Quality Of Life Report
Conditions: Chronic Low Back Pain
Intervention: Health-Related Quality Of Life Report
August 16, 2019
46
NCT04060940
Recruiting
Recruiting
Emotion Regulation Therapy for Clinical Worry and Rumination
Conditions: Anxiety Disorders and Symptoms; Depression, Anxiety; Generalized Anxiety Disorder; Emotional Dysfunction
Intervention: Emotion Regulation Therapy: 8-session Version, Emotion Regulation Therapy: 16-session Version
Conditions: Anxiety Disorders and Symptoms; Depression, Anxiety; Generalized Anxiety Disorder; Emotional Dysfunction
Intervention: Emotion Regulation Therapy: 8-session Version, Emotion Regulation Therapy: 16-session Version
August 14, 2019
47
NCT04060927
Not yet recruiting
Not yet recruiting
Pilot Study of SGRT Alone vs. SGRT With Fiducials for Breath Hold SBRT tx of the Lung
Conditions: Lung
Intervention: SGRT
Conditions: Lung
Intervention: SGRT
August 16, 2019
48
NCT04060914
Not yet recruiting
Not yet recruiting
LOwer Maintenance Dose TICagrelor in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention
Conditions: Antiplatelet Therapy; Coronary Artery Disease; Percutaneous Coronary Intervention
Intervention: Ticagrelor 90mg, Ticagrelor 90mg/60mg, Clopidogrel 75mg
Conditions: Antiplatelet Therapy; Coronary Artery Disease; Percutaneous Coronary Intervention
Intervention: Ticagrelor 90mg, Ticagrelor 90mg/60mg, Clopidogrel 75mg
August 16, 2019
49
NCT04060901
Not yet recruiting
Not yet recruiting
Compassion-Centered Spiritual Health for Faculty and Staff
Conditions: Health Behavior
Intervention: CCSH Intervention For Teams
Conditions: Health Behavior
Intervention: CCSH Intervention For Teams
August 16, 2019
50
NCT04060888
Not yet recruiting
Not yet recruiting
A Study of Ustekinumab in Chinese Participants With Active Systemic Lupus Erythematosus
Conditions: Lupus Erythematosus, Systemic
Intervention: Ustekinumab (approximately 6 Mg/kg), Ustekinumab 90 Milligram (mg), Placebo
Conditions: Lupus Erythematosus, Systemic
Intervention: Ustekinumab (approximately 6 Mg/kg), Ustekinumab 90 Milligram (mg), Placebo
August 16, 2019
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.