Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED,0.050] ALL
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NCTID/Status
Study
Last Changed
1
NCT03776591
Recruiting
Recruiting
Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer
Conditions: Complication; Quality of Life; Surgical Procedure, Unspecified; Lymph Node Metastases; Circulating Tumor Cell
Intervention: Open Surgery, Right Colectomy, Laparoscopic Surgery, Central Lymphadenectomy And Vascular Ligation
Conditions: Complication; Quality of Life; Surgical Procedure, Unspecified; Lymph Node Metastases; Circulating Tumor Cell
Intervention: Open Surgery, Right Colectomy, Laparoscopic Surgery, Central Lymphadenectomy And Vascular Ligation
December 13, 2018
2
NCT03776578
Recruiting
Recruiting
Oral Cancer With Wide Excision and Free Flap Reconstruction
Conditions: Head and Neck Cancer
Intervention: Swallow Fuction And Swallow Training
Conditions: Head and Neck Cancer
Intervention: Swallow Fuction And Swallow Training
December 12, 2018
3
NCT03776565
Recruiting
Recruiting
Comparison of Antrum Surface Between Women With Operative Hysteroscopy or Planned Caesarean Section
Conditions: Pregnancy Related
Intervention: Ultrasound
Conditions: Pregnancy Related
Intervention: Ultrasound
December 13, 2018
4
NCT03776552
Not yet recruiting
Not yet recruiting
Effect of Gradual Versus Rapid Weight Loss
Conditions: Obesity
Intervention: Low Energy Diet (LED), Gradual Weight Loss (GWL)
Conditions: Obesity
Intervention: Low Energy Diet (LED), Gradual Weight Loss (GWL)
December 13, 2018
5
NCT03776539
Not yet recruiting
Not yet recruiting
A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02
Conditions: Impaired Renal Function
Intervention: ELX-02
Conditions: Impaired Renal Function
Intervention: ELX-02
December 13, 2018
6
NCT03776526
Recruiting
Recruiting
Researching the Effects of Sleep on STep Count dUring the Postoperative Period
Conditions: Hip Fractures; Sleep; Postoperative Complications; Delirium
Intervention: Fitbit® Alta HR Sleep Monitoring
Conditions: Hip Fractures; Sleep; Postoperative Complications; Delirium
Intervention: Fitbit® Alta HR Sleep Monitoring
December 12, 2018
7
NCT03776513
Recruiting
Recruiting
Neuro-cognitive Impact of Juvenile Obesity
Conditions: Pediatric Obesity; Behavior and Behavior Mechanisms; Emotions
Intervention: An MRI Examination
Conditions: Pediatric Obesity; Behavior and Behavior Mechanisms; Emotions
Intervention: An MRI Examination
December 13, 2018
8
NCT03776500
Not yet recruiting
Not yet recruiting
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of PBTZ169 in Multiple Dosing
Conditions: Tuberculosis, Pulmonary
Intervention: PBTZ169, Placebo
Conditions: Tuberculosis, Pulmonary
Intervention: PBTZ169, Placebo
December 13, 2018
9
NCT03776487
Not yet recruiting
Not yet recruiting
Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer
Conditions: Clinical Stage 0 Gastric Cancer AJCC v8; Clinical Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage I Gastric Cancer AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IIB Gastric Cancer AJCC v8; Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Gastric Adenocarcinoma; Localized Gastric Carcinoma; Localized Gastroesophageal Junction Adenocarcinoma; Pathologic Stage 0 Gastric Cancer AJCC v8; Pathologic Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage I Gastric Cancer AJCC v8; Pathologic Stage IA Gastric Cancer AJCC v8; Pathologic Stage IA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IB Gastric Cancer AJCC v8; Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIA Gastric Cancer AJCC v8; Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIB Gastric Cancer AJCC v8; Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIIA Gastric Cancer AJCC v8; Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Intervention: Fluorouracil, Intensity-Modulated Radiation Therapy, Ipilimumab, Nivolumab, Oxaliplatin, Therapeutic Conventional Surgery
Conditions: Clinical Stage 0 Gastric Cancer AJCC v8; Clinical Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage I Gastric Cancer AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IIB Gastric Cancer AJCC v8; Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Gastric Adenocarcinoma; Localized Gastric Carcinoma; Localized Gastroesophageal Junction Adenocarcinoma; Pathologic Stage 0 Gastric Cancer AJCC v8; Pathologic Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage I Gastric Cancer AJCC v8; Pathologic Stage IA Gastric Cancer AJCC v8; Pathologic Stage IA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IB Gastric Cancer AJCC v8; Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIA Gastric Cancer AJCC v8; Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIB Gastric Cancer AJCC v8; Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IIIA Gastric Cancer AJCC v8; Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Intervention: Fluorouracil, Intensity-Modulated Radiation Therapy, Ipilimumab, Nivolumab, Oxaliplatin, Therapeutic Conventional Surgery
December 13, 2018
10
NCT03776474
Not yet recruiting
Not yet recruiting
Determine Immunoglobulin G4 (IgG4) Standards for Cow's Milk and Egg in Different Populations of Allergic and Non-allergic Children
Conditions: Food Allergy in Children
Intervention: Blood Collection
Conditions: Food Allergy in Children
Intervention: Blood Collection
December 13, 2018
11
NCT03776461
Not yet recruiting
Not yet recruiting
Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Conditions: Rhytides; Wrinkle
Intervention: Venus Viva
Conditions: Rhytides; Wrinkle
Intervention: Venus Viva
December 13, 2018
12
NCT03776448
Not yet recruiting
Not yet recruiting
The Effect of 2 Grams Daily Supplementation of Sativa Nigra Oil on Blood Glucose Levels of Adults.
Conditions: Diabetes Mellitus
Intervention: Sativa Nigra Oil Softgels, Activated Charcoal Softgels
Conditions: Diabetes Mellitus
Intervention: Sativa Nigra Oil Softgels, Activated Charcoal Softgels
December 13, 2018
13
NCT03776435
Recruiting
Recruiting
CT Carcinogenic Risk in Patients With Appendicitis
Conditions: Computed Tomography; Carcinogenesis; Radiation Exposure; Appendicitis
Intervention: Abdomen CT
Conditions: Computed Tomography; Carcinogenesis; Radiation Exposure; Appendicitis
Intervention: Abdomen CT
December 13, 2018
14
NCT03776422
Recruiting
Recruiting
Homeless Youth Study - Stepping Stone 2.0
Conditions: Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Intervention: Mobile Self-help Intervention
Conditions: Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Intervention: Mobile Self-help Intervention
December 12, 2018
15
NCT03776409
Not yet recruiting
Not yet recruiting
Safety and Efficacy of Vancomycin Plus Beta-lactams
Conditions: Critical Illness
Conditions: Critical Illness
December 12, 2018
16
NCT03776396
Completed
Completed
Perioperative Goal Directed Therapy in Kidney Transplantation
Conditions: Kidney Transplant; Complications
Conditions: Kidney Transplant; Complications
December 11, 2018
17
NCT03776383
Enrolling by invitation
Enrolling by invitation
Providing Antibiotic Prescribing Feedback to Primary Care Physicians: The Ontario Program To Improve AntiMicrobial USE
Conditions: Antibiotic Prescribing Audit and Feedback
Intervention: Antibiotic Use Feedback Letter
Conditions: Antibiotic Prescribing Audit and Feedback
Intervention: Antibiotic Use Feedback Letter
December 13, 2018
18
NCT03776370
Recruiting
Recruiting
Preserving Left Colonic Artery During Radical Resection of Rectal Cancer
Conditions: Postoperative Complications; Proteinosis
Conditions: Postoperative Complications; Proteinosis
December 11, 2018
19
NCT03776357
Not yet recruiting
Not yet recruiting
A Rehabilitation Tool to Determine Patient's Stay in Hospital After Joint Replacement
Conditions: Total Joint Replacement Surgery
Intervention: VERA Clinic
Conditions: Total Joint Replacement Surgery
Intervention: VERA Clinic
December 13, 2018
20
NCT03776344
Recruiting
Recruiting
Virtual Reality for Post Operative Pain
Conditions: Pain, Postoperative
Intervention: Virtual Reality Intervention - Nature Treks VR
Conditions: Pain, Postoperative
Intervention: Virtual Reality Intervention - Nature Treks VR
December 13, 2018
21
NCT03776331
Not yet recruiting
Not yet recruiting
Vascular Functions in Myeloma Patients During Anti-tumor Therapy
Conditions: Cardiooncology; Myeloma; Endothelial Dysfunction
Intervention: Flow Mediated Dilation
Conditions: Cardiooncology; Myeloma; Endothelial Dysfunction
Intervention: Flow Mediated Dilation
December 13, 2018
22
NCT03776318
Enrolling by invitation
Enrolling by invitation
Long-Term Follow-up Safety of Clonidine Micropellets
Conditions: Lumbosacral Radiculopathy
Intervention: Long-Term Safety Follow-up
Conditions: Lumbosacral Radiculopathy
Intervention: Long-Term Safety Follow-up
December 12, 2018
23
NCT03776305
Active, not recruiting
Active, not recruiting
Imipenem in Critically Ill Patients
Conditions: Critically Ill Patients With ECMO
Intervention: Imipenem
Conditions: Critically Ill Patients With ECMO
Intervention: Imipenem
December 12, 2018
24
NCT03776292
Recruiting
Recruiting
Cardiopulmonary Changes Prolonged Surgical Abdominal Retractors Application in Supine Versus Lateral Position
Conditions: Cardio-pulmonary
Intervention: Monitoring
Conditions: Cardio-pulmonary
Intervention: Monitoring
December 12, 2018
25
NCT03776279
Recruiting
Recruiting
A Study of Liposome-entrapped Mitoxantrone Hydrochloride Injection in Relapsed/Refractory Peripheral T-cell Lymphoma and NK/T-cell Lymphoma
Conditions: Relapsed or Refractory Peripheral T-cell and NK/T-cell Lymphoma
Intervention: Mitoxantrone Hydrochloride Liposome Injection
Conditions: Relapsed or Refractory Peripheral T-cell and NK/T-cell Lymphoma
Intervention: Mitoxantrone Hydrochloride Liposome Injection
December 13, 2018
26
NCT03776266
Completed
Completed
The Long-term Clinical Outcomes and Patterns of Transfusion in Patients Undergoing Percutaneous Coronary Intervention
Conditions: Erythrocyte Transfusion; Percutaneous Coronary Intervention; Revascularization
Intervention: Red Blood Cell Transfusion
Conditions: Erythrocyte Transfusion; Percutaneous Coronary Intervention; Revascularization
Intervention: Red Blood Cell Transfusion
December 13, 2018
27
NCT03776253
Recruiting
Recruiting
Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer
Conditions: Advanced Lung Carcinoma; Malignant Female Reproductive System Neoplasm; Stage III Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8
Intervention: Psychosocial Care Conquer Fear Support Intervention (psychoeducation, Attention Training, Worry Management, And Detached Mindfulness Components), Questionnaire Administration
Conditions: Advanced Lung Carcinoma; Malignant Female Reproductive System Neoplasm; Stage III Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8
Intervention: Psychosocial Care Conquer Fear Support Intervention (psychoeducation, Attention Training, Worry Management, And Detached Mindfulness Components), Questionnaire Administration
December 12, 2018
28
NCT03776240
Not yet recruiting
Not yet recruiting
A Study to Demonstrate the Equivalent Pharmacokinetic Properties of a Single Intravenous Dose of HD201 and EU-Herceptin® and US-Herceptin® in Healthy Male Subjects
Conditions: Healthy Volunteers
Intervention: HD201, EU-Herceptin, US-Herceptin
Conditions: Healthy Volunteers
Intervention: HD201, EU-Herceptin, US-Herceptin
December 13, 2018
29
NCT03776227
Not yet recruiting
Not yet recruiting
A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions
Conditions: Type 2 Diabetes Mellitus; Healthy Subjects
Intervention: Sotagliflozin (SAR439954)
Conditions: Type 2 Diabetes Mellitus; Healthy Subjects
Intervention: Sotagliflozin (SAR439954)
December 12, 2018
30
NCT03776214
Recruiting
Recruiting
Surgery in Addition to the Medical Treatment of Lymphedema
Conditions: Optimal Treatment of Lymphedema
Conditions: Optimal Treatment of Lymphedema
December 13, 2018
31
NCT03776201
Recruiting
Recruiting
Merging Attentional Focus and Balance Training to Reduce Fall Risk in Older Adults
Conditions: Accidental Fall
Intervention: Balance Training
Conditions: Accidental Fall
Intervention: Balance Training
December 13, 2018
33
NCT03776175
Not yet recruiting
Not yet recruiting
A Study To Assess Pharmacodynamics, Safety And Tolerability Of PF-05221304 And PF-06865571 Co-Administered For 6 Weeks In Adults With Non-Alcoholic Fatty Liver Disease.
Conditions: Non-Alcoholic Fatty Liver Disease (NAFLD)
Intervention: PF-05221304 Monotherapy, PF-06865571 Monotherapy, Placebo, PF-05221304 And PF-06865571 Combination
Conditions: Non-Alcoholic Fatty Liver Disease (NAFLD)
Intervention: PF-05221304 Monotherapy, PF-06865571 Monotherapy, Placebo, PF-05221304 And PF-06865571 Combination
December 12, 2018
34
NCT03776162
Withheld
Withheld
December 13, 2018
35
NCT03776149
Enrolling by invitation
Enrolling by invitation
Cardiovascular Function in Cancer Survivors
Conditions: Cancer Survivor With History of Anthracycline Chemotherapy
Conditions: Cancer Survivor With History of Anthracycline Chemotherapy
December 13, 2018
36
NCT03776136
Not yet recruiting
Not yet recruiting
Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) for Advanced Melanoma in Anti-Programmed Death-1/Programmed Death-Ligand 1 (PD-1/L1)-Exposed Participants (MK-7902-004/E7080-G000-225/LEAP-004)
Conditions: Advanced Melanoma
Intervention: Lenvatinib, Pembrolizumab
Conditions: Advanced Melanoma
Intervention: Lenvatinib, Pembrolizumab
December 13, 2018
37
NCT03776123
Not yet recruiting
Not yet recruiting
Post Marketing Surveillance to Observe Safety and Effectiveness of CABOMETYX™ in Korea.
Conditions: Renal Cell Carcinoma
Conditions: Renal Cell Carcinoma
December 13, 2018
38
NCT03776110
Completed
Completed
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GRT9906 Prolonged Release Tablets After Dose Escalation in Healthy Subjects
Conditions: Pharmacokinetics
Intervention: GRT9906 PR Tablet, Placebo
Conditions: Pharmacokinetics
Intervention: GRT9906 PR Tablet, Placebo
December 13, 2018
39
NCT03776097
Active, not recruiting
Active, not recruiting
Long-term Follow-up Observation After Surgical Treatment of Peri-implantitis in Multicenter Post Market Clinical Study
Conditions: Peri-implantitis
Intervention: Observational Study
Conditions: Peri-implantitis
Intervention: Observational Study
December 13, 2018
40
NCT03776084
Not yet recruiting
Not yet recruiting
Compliance With Continuous Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea Syndrome
Conditions: Sleep Apnea, Obstructive
Intervention: Continuous Positive Airway Pressure
Conditions: Sleep Apnea, Obstructive
Intervention: Continuous Positive Airway Pressure
December 13, 2018
41
NCT03776071
Not yet recruiting
Not yet recruiting
A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1
Conditions: Glioblastoma
Intervention: Enzastaurin Hydrochloride, Placebo, Temozolomide, Radiotherapy
Conditions: Glioblastoma
Intervention: Enzastaurin Hydrochloride, Placebo, Temozolomide, Radiotherapy
December 13, 2018
42
NCT03776058
Completed
Completed
Safety, Tolerability, and Clinical Effects of Twice-daily Doses of Cinacalcet (AMG 073) in Adults With Primary Hyperparathyroidism (HPT)
Conditions: Primary Hyperparathyroidism
Intervention: Cinacalcet, Placebo
Conditions: Primary Hyperparathyroidism
Intervention: Cinacalcet, Placebo
December 13, 2018
43
NCT03776045
Completed
Completed
PROState Cancer Patients Initiating Hormone Therapy: Effect of Exercise on CARDIOvascular Health (PROSCARDIO)
Conditions: Prostate Cancer
Conditions: Prostate Cancer
December 12, 2018
44
NCT03776032
Completed
Completed
A Novel Erythropoiesis Stimulating Protein (NESP; Darbopoetin Alfa) for the Treatment of Anemia in Lung Cancer Patients Receiving Multi-cycle Platinum-Containing Chemotherapy
Conditions: Anemia
Intervention: Darbepoetin Alfa, Placebo
Conditions: Anemia
Intervention: Darbepoetin Alfa, Placebo
December 13, 2018
45
NCT03776019
Not yet recruiting
Not yet recruiting
Efficacy of Audio-Visual-Perception-Enhancement (AVWF®) Method in Chronic Pain Patients
Conditions: Pain; Stress
Intervention: AVWF Device
Conditions: Pain; Stress
Intervention: AVWF Device
December 13, 2018
46
NCT03776006
Not yet recruiting
Not yet recruiting
Registry: TPLA for LUTS
Conditions: Lower Urinary Tract Symptoms; Benign Prostate Hyperplasia; Benign Prostatic Hypertrophy With Outflow Obstruction
Intervention: Transperineal Laser Ablation
Conditions: Lower Urinary Tract Symptoms; Benign Prostate Hyperplasia; Benign Prostatic Hypertrophy With Outflow Obstruction
Intervention: Transperineal Laser Ablation
December 13, 2018
47
NCT03775993
Not yet recruiting
Not yet recruiting
Treatment of GHD Associated With CHF: A Randomized, Double-Blind, Placebo-Controlled Study
Conditions: Heart Failure; Growth Hormone Deficiency
Intervention: Human Growth Hormone, Placebo
Conditions: Heart Failure; Growth Hormone Deficiency
Intervention: Human Growth Hormone, Placebo
December 12, 2018
48
NCT03775980
Not yet recruiting
Not yet recruiting
CIRSE Emprint Microwave Ablation Registry
Conditions: Colorectal Neoplasms Malignant; Neoplasm Metastasis
Intervention: Emprint Microwave Ablation System
Conditions: Colorectal Neoplasms Malignant; Neoplasm Metastasis
Intervention: Emprint Microwave Ablation System
December 13, 2018
49
NCT03775967
Recruiting
Recruiting
Estimation of Sialic Acid and IL10 Levels in Stage 1 and 2 Periodontitis Patients
Conditions: Periodontal Disease
Intervention: Sialic Acid, IL10
Conditions: Periodontal Disease
Intervention: Sialic Acid, IL10
December 13, 2018
50
NCT03775954
Recruiting
Recruiting
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
Conditions: High Risk Pregnancy; Congenital Heart Disease; Fetal Hydrops; Twin Monochorionic Monoamniotic Placenta; Gastroschisis; Fetal Demise; Stillbirth; Fetal Arrhythmia; Long QT Syndrome; Intrauterine Fetal Death; Sudden Infant Death; Pregnancy Loss; Twin Twin Transfusion Syndrome; Birth Defect; Fetal Cardiac Anomaly; Fetal Cardiac Disorder; Fetal Death; Brugada Syndrome
Intervention: Fetal Magnetocardiogram And Neonatal Electrocardiogram
Conditions: High Risk Pregnancy; Congenital Heart Disease; Fetal Hydrops; Twin Monochorionic Monoamniotic Placenta; Gastroschisis; Fetal Demise; Stillbirth; Fetal Arrhythmia; Long QT Syndrome; Intrauterine Fetal Death; Sudden Infant Death; Pregnancy Loss; Twin Twin Transfusion Syndrome; Birth Defect; Fetal Cardiac Anomaly; Fetal Cardiac Disorder; Fetal Death; Brugada Syndrome
Intervention: Fetal Magnetocardiogram And Neonatal Electrocardiogram
December 13, 2018
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.