Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Anemia Sickle Cell
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NCTID/Status
Study
Last Changed
1
NCT02530242
Completed
Completed
Carbon Monoxide Measurement to Screen for Sickle Cell Disease
Conditions: Sickle Cell Anemia
Intervention: End-tidal Carbon Monoxide Subjects, End-tidal Carbon Monoxide Controls
Conditions: Sickle Cell Anemia
Intervention: End-tidal Carbon Monoxide Subjects, End-tidal Carbon Monoxide Controls
December 7, 2015
2
NCT01441375
Completed
Completed
Sickle Cell Disease: A Retrospective Chart Review
Conditions: Sickle Cell Anemia
Conditions: Sickle Cell Anemia
October 17, 2012
3
NCT01800526
Enrolling by invitation
Enrolling by invitation
A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: N-Acetylcysteine
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: N-Acetylcysteine
July 9, 2018
4
NCT01527799
Completed
Completed
Exercise Capacity in Pediatric Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Conditions: Sickle Cell Anemia
February 3, 2016
5
NCT03716726
Not yet recruiting
Not yet recruiting
Sickle Cell Anemia WE CARE
Conditions: Sickle Cell Disease
Intervention: WE CARE SDoH Screening Survey, Family Resource Book, Standard Of Care
Conditions: Sickle Cell Disease
Intervention: WE CARE SDoH Screening Survey, Family Resource Book, Standard Of Care
November 27, 2019
6
NCT02961218
Active, not recruiting
Active, not recruiting
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Ilaris, Canakinumab, Placebo
Conditions: Sickle Cell Anemia
Intervention: Ilaris, Canakinumab, Placebo
October 28, 2019
7
NCT00519701
Completed
Completed
Hydroxyurea in Young Children With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Hydroxyurea
Conditions: Sickle Cell Anemia
Intervention: Hydroxyurea
August 22, 2007
8
NCT01558076
Unknown status
Unknown status
Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Conditions: Sickle Cell Anemia
September 21, 2015
9
NCT01703104
Completed
Completed
The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Paludrine + Folic Acid, Paludrine + Folic Acid + Jobelyn
Conditions: Sickle Cell Anemia
Intervention: Paludrine + Folic Acid, Paludrine + Folic Acid + Jobelyn
October 5, 2012
10
NCT03648710
Recruiting
Recruiting
Community Health Workers and mHealth for Sickle Cell Disease Care
Conditions: Sickle Cell Disease
Intervention: Peer Community Health Worker, Mobile Health
Conditions: Sickle Cell Disease
Intervention: Peer Community Health Worker, Mobile Health
January 22, 2019
11
NCT03666806
Active, not recruiting
Active, not recruiting
Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial
Conditions: Preventing Stroke in Sickle Cell Anaemia
Intervention: Influenza Vaccine
Conditions: Preventing Stroke in Sickle Cell Anaemia
Intervention: Influenza Vaccine
September 10, 2018
12
NCT04191213
Recruiting
Recruiting
Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients
Conditions: Sickle Cell Anemia in Children
Intervention: Acacia Senegal Extract, Pectin
Conditions: Sickle Cell Anemia in Children
Intervention: Acacia Senegal Extract, Pectin
December 13, 2019
13
NCT01167023
Completed
Completed
Prasugrel Versus Placebo in Adult Sickle Cell Disease
Conditions: Sickle Cell Anemia
Intervention: Prasugrel, Placebo
Conditions: Sickle Cell Anemia
Intervention: Prasugrel, Placebo
April 9, 2012
14
NCT00489281
Terminated
Terminated
Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders
Conditions: Sickle Cell Disease
Intervention: Cyclophosphamide, Fludarabine, Mycophenolate Mofetil, Sirolimus, Allogeneic Bone Marrow Transplant, Total Body Irradiation - 200, Levetiracetam, Anti-thymocyte Globulin, Total Body Irradiation - 400
Conditions: Sickle Cell Disease
Intervention: Cyclophosphamide, Fludarabine, Mycophenolate Mofetil, Sirolimus, Allogeneic Bone Marrow Transplant, Total Body Irradiation - 200, Levetiracetam, Anti-thymocyte Globulin, Total Body Irradiation - 400
March 25, 2019
15
NCT02824471
Recruiting
Recruiting
Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
Conditions: Sickle Cell Disease
Intervention: SCD Group
Conditions: Sickle Cell Disease
Intervention: SCD Group
March 21, 2019
16
NCT00294541
Terminated
Terminated
A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: ICA-17043
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: ICA-17043
September 10, 2007
17
NCT02475993
Completed
Completed
SMART Mobile Application Technology Utilization in the Treatment of Sickle Cell Disease Post Day Hospital Discharge
Conditions: Sickle Cell Disease
Intervention: SMART App
Conditions: Sickle Cell Disease
Intervention: SMART App
October 17, 2019
18
NCT04218084
Not yet recruiting
Not yet recruiting
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Voxelotor, Placebos
Conditions: Sickle Cell Disease
Intervention: Voxelotor, Placebos
January 2, 2020
19
NCT02162225
Withdrawn
Withdrawn
Study of Beet Juice for Patients With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Beet Juice (Unbeetable)
Conditions: Sickle Cell Anemia
Intervention: Beet Juice (Unbeetable)
July 31, 2018
20
NCT03401125
Withdrawn
Withdrawn
Risk Factors for Allo-immunization in Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Medical File Data Collection
Conditions: Sickle Cell Disease
Intervention: Medical File Data Collection
July 25, 2018
21
NCT02580565
Completed
Completed
Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease
Conditions: Sickle Cell Disease
Intervention: Telephone Interview
Conditions: Sickle Cell Disease
Intervention: Telephone Interview
May 28, 2018
22
NCT03012555
Completed
Completed
Vitamin D3 in Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease
Conditions: Sickle Cell Disease
January 17, 2018
23
NCT03492931
Completed
Completed
PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4)
Conditions: Sickle Cell Disease
Intervention: Ticagrelor
Conditions: Sickle Cell Disease
Intervention: Ticagrelor
June 7, 2019
24
NCT02709681
Completed
Completed
Hydroxyurea in the Treatment of Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Physician Standard-of-care In SCD Patients
Conditions: Sickle Cell Disease
Intervention: Physician Standard-of-care In SCD Patients
October 5, 2017
25
NCT03368924
Completed
Completed
Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia:
Conditions: Sickle Cell Disease
Intervention: SCA Patients (SS Genotype)
Conditions: Sickle Cell Disease
Intervention: SCA Patients (SS Genotype)
December 5, 2017
26
NCT02712346
Active, not recruiting
Active, not recruiting
The Role of Endothelin-1 in Sickle Cell Disease
Conditions: Sickle Cell Anemia
Intervention: Ambrisentan, Placebo
Conditions: Sickle Cell Anemia
Intervention: Ambrisentan, Placebo
July 15, 2019
27
NCT04205123
Recruiting
Recruiting
Biological, Genetic and Environmental Involved in the Complications of Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Sickle Cell Syndrome
Conditions: Sickle Cell Disease
Intervention: Sickle Cell Syndrome
December 17, 2019
28
NCT00672789
Completed
Completed
Adherence to Hydroxyurea in Children With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Blood Smear Education, Standard Education
Conditions: Sickle Cell Anemia
Intervention: Blood Smear Education, Standard Education
May 24, 2013
29
NCT01137721
Completed
Completed
State Of The Art Functional Imaging In Sickle Cell Disease
Conditions: Sickle Cell Anemia
Conditions: Sickle Cell Anemia
August 21, 2018
30
NCT00481039
Completed
Completed
Sickle Cell Anemia in an Arab Bedouin Village in the Northern Israel
Conditions: Sickle Cell Disease
Intervention: Medical History And Basic Laboratory Analysis
Conditions: Sickle Cell Disease
Intervention: Medical History And Basic Laboratory Analysis
September 3, 2009
31
NCT01566890
Active, not recruiting
Active, not recruiting
Microvascular Blood Flow in Sickle Cell Anemia
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: Regadenoson Infusion With Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: Regadenoson Infusion With Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound, Contrast-enhanced Ultrasound
July 8, 2019
32
NCT03786549
Recruiting
Recruiting
Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Pediatric-adult Care Transition Program
Conditions: Sickle Cell Disease
Intervention: Pediatric-adult Care Transition Program
November 28, 2019
33
NCT01783691
Completed
Completed
Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD)
Conditions: Sickle Cell Disease
Intervention: NKTT120
Conditions: Sickle Cell Disease
Intervention: NKTT120
June 25, 2015
34
NCT03405402
Recruiting
Recruiting
Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization
Conditions: Sickle Cell Disease
Intervention: Blood Sampling
Conditions: Sickle Cell Disease
Intervention: Blood Sampling
July 11, 2018
35
NCT01123369
Completed
Completed
Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease
Conditions: Sickle Cell Disease
Conditions: Sickle Cell Disease
September 13, 2010
36
NCT00745420
Completed
Completed
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)
Conditions: Sickle Cell Disease
Intervention: Hematopoietic Stem Cell Transplantation
Conditions: Sickle Cell Disease
Intervention: Hematopoietic Stem Cell Transplantation
April 11, 2018
37
NCT04001907
Active, not recruiting
Active, not recruiting
Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia
Conditions: Sickle Cell Anemia
Intervention: Resistance Exercise, Β-hydroxy-β-methylbutyrate, Placebo
Conditions: Sickle Cell Anemia
Intervention: Resistance Exercise, Β-hydroxy-β-methylbutyrate, Placebo
June 26, 2019
38
NCT03753854
Recruiting
Recruiting
Sleep Apnea in Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Polysomnography And Oxygen Saturation Exam, Calculation Of VOC Frequency Between The First Polysomnography And The End Of The First Year Of Continuous Positive Airway Pressure Treatment, Blood Samples, Physiological Measurements, Continuous Positive Airway Pressure
Conditions: Sickle Cell Disease
Intervention: Polysomnography And Oxygen Saturation Exam, Calculation Of VOC Frequency Between The First Polysomnography And The End Of The First Year Of Continuous Positive Airway Pressure Treatment, Blood Samples, Physiological Measurements, Continuous Positive Airway Pressure
December 13, 2018
39
NCT00639392
Withdrawn
Withdrawn
Phase 1 Study of Zoledronic Acid in Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Placebo, Zoledronic Acid
Conditions: Sickle Cell Disease
Intervention: Placebo, Zoledronic Acid
November 10, 2011
40
NCT02565849
Completed
Completed
Study of Ventilatory Mechanics in Patients With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Conditions: Sickle Cell Anemia
September 30, 2015
41
NCT00911495
Completed
Completed
Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: GMI-1070
Conditions: Sickle Cell Disease
Intervention: GMI-1070
August 17, 2016
42
NCT02467257
Completed
Completed
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Gum Arabic
Conditions: Sickle Cell Anemia
Intervention: Gum Arabic
June 5, 2015
43
NCT02186418
Recruiting
Recruiting
Gene Transfer for Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: Gene Transfer
Conditions: Sickle Cell Disease; Sickle Cell Anemia
Intervention: Gene Transfer
June 3, 2019
44
NCT02038478
Recruiting
Recruiting
Allograft for Sickle Cell Disease and Thalassemia
Conditions: Sickle Cell Disease and Thalassemia
Intervention: Donor Stem Cell Transplantation
Conditions: Sickle Cell Disease and Thalassemia
Intervention: Donor Stem Cell Transplantation
September 6, 2019
45
NCT02090296
Withdrawn
Withdrawn
Risk-based Therapy for Sickle Cell Anemia: A Feasibility Study
Conditions: Sickle Cell Anemia
Intervention: Hydroxyurea, Placebo
Conditions: Sickle Cell Anemia
Intervention: Hydroxyurea, Placebo
October 16, 2017
46
NCT02769845
Active, not recruiting
Active, not recruiting
SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia
Conditions: Sickle Cell Anemia
Intervention: Hydroxyurea, TCD Examination
Conditions: Sickle Cell Anemia
Intervention: Hydroxyurea, TCD Examination
January 6, 2020
47
NCT03243812
Recruiting
Recruiting
Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Blood Sampling, Maximum Voluntary Contraction (MVC) Test Force, Localized Muscle Endurance Test, Self-paced Six-minute Walk Test
Conditions: Sickle Cell Disease
Intervention: Blood Sampling, Maximum Voluntary Contraction (MVC) Test Force, Localized Muscle Endurance Test, Self-paced Six-minute Walk Test
August 22, 2019
48
NCT00784082
Completed
Completed
Inflammatory Response to Hydroxyurea Therapy in Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Hydroxycarbamide, Hydroxyurea (drug)
Conditions: Sickle Cell Disease
Intervention: Hydroxycarbamide, Hydroxyurea (drug)
January 30, 2013
49
NCT02868138
Completed
Completed
Study of Hydroxyurea to Treat Sickle Cell Disease
Conditions: Sickle Cell Disease
Conditions: Sickle Cell Disease
August 13, 2016
50
NCT03997903
Not yet recruiting
Not yet recruiting
Imatinib for Pain in Sickle Cell Anemia
Conditions: Sickle Cell Disease
Intervention: Imatinib Mesylate
Conditions: Sickle Cell Disease
Intervention: Imatinib Mesylate
June 25, 2019
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Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
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In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
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NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
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Examples:
National Cancer Institute
Mayo Clinic
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It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
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It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
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When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
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weight loss
heart failure
suicide
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to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
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Examples:
clofibrate
cyclosporine
vitamin e
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Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.