Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Eosinophilia [STUDY:DISEASE] )
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NCTID/Status
Study
Last Changed
1
NCT02217332
Completed
Completed
Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia
Conditions: Chronic Sinusitis With Nasal Polyps and Eosinophilia
Intervention: Dexpramipexole
Conditions: Chronic Sinusitis With Nasal Polyps and Eosinophilia
Intervention: Dexpramipexole
December 13, 2017
3
NCT00090662
Recruiting
Recruiting
Collection of Peripheral Blood and Bone Marrow From Healthy Donors for Use in In Vitro Research
Conditions: Eosinophilia
Conditions: Eosinophilia
August 7, 2019
4
NCT03810183
Not yet recruiting
Not yet recruiting
A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia
Conditions: COPD
Intervention: QAW039, Placebo
Conditions: COPD
Intervention: QAW039, Placebo
January 17, 2019
5
NCT02360696
Completed
Completed
Functional Dyspepsia (FD) - Clinical Response to Montelukast in Children
Conditions: Eosinophilia; Dyspepsia
Conditions: Eosinophilia; Dyspepsia
May 15, 2019
6
NCT02581514
Recruiting
Recruiting
Eosinophilia Diagnosis
Conditions: Hypereosinophilic Syndrome
Intervention: Scheduled Exams And Diagnosis
Conditions: Hypereosinophilic Syndrome
Intervention: Scheduled Exams And Diagnosis
June 4, 2019
7
NCT01545726
Completed
Completed
Safety and Efficacy of QAW039 in Sputum Eosinophilia and Persistent Asthma
Conditions: Asthma
Intervention: QAW039, Placebo
Conditions: Asthma
Intervention: QAW039, Placebo
October 8, 2013
8
NCT01987076
Unknown status
Unknown status
Comparison Between Corticosteroid and Topical Steroids in the DRESS
Conditions: Drug Rash With Eosinophilia and Systemic Symptoms
Intervention: Prednisone, Clobetasol
Conditions: Drug Rash With Eosinophilia and Systemic Symptoms
Intervention: Prednisone, Clobetasol
July 29, 2015
9
NCT04018118
Recruiting
Recruiting
Natural History of Hypereosinophilia and Hypereosinophilic Syndromes
Conditions: Eosinophilia; Hypereosinophilic Syndrome
Intervention: Biological Sample
Conditions: Eosinophilia; Hypereosinophilic Syndrome
Intervention: Biological Sample
July 10, 2019
10
NCT03018808
Recruiting
Recruiting
Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and Eosinophilia Among Primary Care Patients
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Minimal Questionnaire, Medical Interview, CAT, Blood Test, Anthropometric Measures, Oximetry
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Minimal Questionnaire, Medical Interview, CAT, Blood Test, Anthropometric Measures, Oximetry
June 24, 2019
11
NCT01111305
Completed
Completed
Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis
Conditions: Loiasis
Intervention: Reslizumab, Diethylcarbamazine, Placebo
Conditions: Loiasis
Intervention: Reslizumab, Diethylcarbamazine, Placebo
October 30, 2017
12
NCT02484248
Recruiting
Recruiting
Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia
Conditions: Functional Dyspepsia
Intervention: Ketotifen, Placebo
Conditions: Functional Dyspepsia
Intervention: Ketotifen, Placebo
August 3, 2018
13
NCT00001406
Recruiting
Recruiting
Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia
Conditions: Immune System Diseases; Eosinophilia; Helminthiasis; Hypersensitivity; Parasitic Disease
Conditions: Immune System Diseases; Eosinophilia; Helminthiasis; Hypersensitivity; Parasitic Disease
June 14, 2019
14
NCT03312686
Recruiting
Recruiting
Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study
Conditions: Eosinophilic Esophagitis
Intervention: Endoflip
Conditions: Eosinophilic Esophagitis
Intervention: Endoflip
March 22, 2018
15
NCT00230334
Withdrawn
Withdrawn
Phase II Gleevec Idiopathic Hypereosinophilic Syndrome
Conditions: Eosinophilia; Hypereosinophilic Syndrome
Intervention: Gleevec
Conditions: Eosinophilia; Hypereosinophilic Syndrome
Intervention: Gleevec
April 11, 2011
16
NCT00148603
Completed
Completed
Montelukast in the Treatment of Duodenal Eosinophilia
Conditions: Eosinophilic Gastroenteritis; Dyspepsia
Intervention: Montelukast
Conditions: Eosinophilic Gastroenteritis; Dyspepsia
Intervention: Montelukast
December 26, 2011
17
NCT03696914
Completed
Completed
Intense Airway Eosinophilia in Asthma
Conditions: Asthma; Eosinophilic Asthma
Conditions: Asthma; Eosinophilic Asthma
October 3, 2018
18
NCT03801434
Not yet recruiting
Not yet recruiting
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders
Conditions: BCR-JAK2 Fusion Protein Expression; Blasts 20 Percent or Less of Peripheral Blood White Cells; Blasts More Than 5 Percent of Bone Marrow Nucleated Cells; Blasts More Than 5 Percent of Peripheral Blood White Cells; Blasts Under 20 Percent of Bone Marrow Nucleated Cells; Chronic Eosinophilic Leukemia, Not Otherwise Specified; Eosinophilia; Hepatomegaly; Hypereosinophilic Syndrome; JAK2 Gene Mutation; Splenomegaly; TEL-JAK2 Fusion Protein Expression
Intervention: Ruxolitinib
Conditions: BCR-JAK2 Fusion Protein Expression; Blasts 20 Percent or Less of Peripheral Blood White Cells; Blasts More Than 5 Percent of Bone Marrow Nucleated Cells; Blasts More Than 5 Percent of Peripheral Blood White Cells; Blasts Under 20 Percent of Bone Marrow Nucleated Cells; Chronic Eosinophilic Leukemia, Not Otherwise Specified; Eosinophilia; Hepatomegaly; Hypereosinophilic Syndrome; JAK2 Gene Mutation; Splenomegaly; TEL-JAK2 Fusion Protein Expression
Intervention: Ruxolitinib
January 9, 2019
19
NCT00939263
Unknown status
Unknown status
Development, Validation and Evaluation of an Adult and Pediatric Eosinophilic Esophagitis Activity Index
Conditions: Deglutition Disorders; Esophageal Diseases; Eosinophilia
Intervention: Assessment Of Disease Activity Using The EEsAI
Conditions: Deglutition Disorders; Esophageal Diseases; Eosinophilia
Intervention: Assessment Of Disease Activity Using The EEsAI
September 15, 2015
20
NCT03450083
Recruiting
Recruiting
Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis
Conditions: Chronic Rhinosinusitis (Diagnosis); Nasal Polyps; Eosinophilia
Intervention: Benralizumab, Placebo
Conditions: Chronic Rhinosinusitis (Diagnosis); Nasal Polyps; Eosinophilia
Intervention: Benralizumab, Placebo
February 25, 2019
21
NCT02268253
Recruiting
Recruiting
SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Primary Eosinophilic Disorder, Myelofibrosis, Chronic Myelomonocytic Leukemia)
Conditions: Myelofibrosis; Chronic Myelomonocytic Leukemia
Intervention: SL-401
Conditions: Myelofibrosis; Chronic Myelomonocytic Leukemia
Intervention: SL-401
February 27, 2019
22
NCT00267501
Recruiting
Recruiting
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
Conditions: Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease; Food Allergy
Conditions: Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease; Food Allergy
November 10, 2015
23
NCT03989635
Not yet recruiting
Not yet recruiting
Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma.
Conditions: Asthma; Asthma, Bronchial; Bronchial Asthma; Eosinophilia; Physiological Effects of Drugs
Intervention: QAW039
Conditions: Asthma; Asthma, Bronchial; Bronchial Asthma; Eosinophilia; Physiological Effects of Drugs
Intervention: QAW039
June 14, 2019
24
NCT01524536
Recruiting
Recruiting
Steroid Treatment for Hypereosinophilic Syndrome
Conditions: Eosinophilia; Hypereosinophilia; Leukocyte Disorder; Hematologic Diseases
Intervention: Corticosteroids
Conditions: Eosinophilia; Hypereosinophilia; Leukocyte Disorder; Hematologic Diseases
Intervention: Corticosteroids
March 28, 2019
25
NCT03470311
Recruiting
Recruiting
Benralizumab in Patients With Inadequate Response to Anti-IL5 Monoclonal Antibody Therapies
Conditions: Severe Prednisone Dependent Eosinophilic Asthma
Intervention: Benralizumab, Placebo
Conditions: Severe Prednisone Dependent Eosinophilic Asthma
Intervention: Benralizumab, Placebo
March 18, 2019
26
NCT03237221
Recruiting
Recruiting
Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma
Conditions: Asthma; Chest Syndrome; Clinical Anxiety; Clinical Depression; Lung Function; Quality of Life; Eosinophilia; Nitric Oxide; Airway Responsiveness; Induced Sputum
Intervention: Treat Patient According To Global Initiative For Asthma (GINA) Guideline
Conditions: Asthma; Chest Syndrome; Clinical Anxiety; Clinical Depression; Lung Function; Quality of Life; Eosinophilia; Nitric Oxide; Airway Responsiveness; Induced Sputum
Intervention: Treat Patient According To Global Initiative For Asthma (GINA) Guideline
August 1, 2017
27
NCT01382563
Active, not recruiting
Active, not recruiting
Registry for Eosinophilic Gastrointestinal Disorders (REGID)
Conditions: Eosinophilic Gastrointestinal Disorders (EGID); Eosinophilic Esophagitis; Eosinophilic Disorder
Conditions: Eosinophilic Gastrointestinal Disorders (EGID); Eosinophilic Esophagitis; Eosinophilic Disorder
January 20, 2017
28
NCT02130882
Active, not recruiting
Active, not recruiting
Study to Evaluate Safety and Efficacy of Benralizumab in Subjects With Hypereosinophilic Syndrome
Conditions: Hypereosinophilic Syndrome
Intervention: Benralizumab, Placebo
Conditions: Hypereosinophilic Syndrome
Intervention: Benralizumab, Placebo
July 30, 2019
29
NCT00044304
Recruiting
Recruiting
Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome
Conditions: Hypereosinophilic Syndrome
Intervention: Imatinib Mesylate
Conditions: Hypereosinophilic Syndrome
Intervention: Imatinib Mesylate
March 19, 2019
30
NCT01865825
Completed
Completed
Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)?
Conditions: Erosive Esophagitis
Intervention: Esophageal Barium Xray
Conditions: Erosive Esophagitis
Intervention: Esophageal Barium Xray
March 21, 2017
31
NCT03078023
Recruiting
Recruiting
Sponge and Eosinophil Peroxidase (EPO) Staining
Conditions: Eosinophilic Esophagitis
Intervention: Swallowed Sponge Device
Conditions: Eosinophilic Esophagitis
Intervention: Swallowed Sponge Device
April 4, 2019
32
NCT00017862
Completed
Completed
Anti-Interleukin-5 Antibody to Treat Hypereosinophilic Syndrome
Conditions: Hypereosinophilic Syndrome
Intervention: SCH55700
Conditions: Hypereosinophilic Syndrome
Intervention: SCH55700
March 3, 2008
33
NCT03069573
Unknown status
Unknown status
Phenotypic Characterization and Biomarkers Investigation for Eosinophilic Esophagitis in Pediatric Patients
Conditions: Eosinophilic Esophagitis; Gastroesophageal Reflux
Conditions: Eosinophilic Esophagitis; Gastroesophageal Reflux
February 27, 2017
34
NCT00267475
Completed
Completed
Data Bank for Eosinophilic Disorders
Conditions: Eosinophilic Esophagitis; Gastritis; Enteritis; Eosinophilic Colitis; Eosinophilic Gastroenteritis
Conditions: Eosinophilic Esophagitis; Gastritis; Enteritis; Eosinophilic Colitis; Eosinophilic Gastroenteritis
September 17, 2013
35
NCT02233426
Unknown status
Unknown status
Effect of Hypertonic Solutions on Allergic Rhinitis Patients
Conditions: Allergic Rhinitis
Conditions: Allergic Rhinitis
September 3, 2014
36
NCT00505648
Terminated
Terminated
Treatment of Hypersensitivity Syndrome (DRESS) With Tegeline® (Human Immunoglobulin)
Conditions: Drug Hypersensitivity
Intervention: Tegeline®
Conditions: Drug Hypersensitivity
Intervention: Tegeline®
March 23, 2015
37
NCT03788057
Recruiting
Recruiting
Inflammatory Indices in Predicting the Failure of Inhaled Corticosteroids Reduction in Young Participants With Asthma
Conditions: Asthma Chronic
Intervention: ICS Dose Reduction
Conditions: Asthma Chronic
Intervention: ICS Dose Reduction
December 25, 2018
38
NCT01227278
Completed
Completed
A Study to Evaluate the Effectiveness of MEDI-563 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Placebo, Benralizumab 100 Mg
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Placebo, Benralizumab 100 Mg
August 11, 2016
39
NCT01160224
Completed
Completed
April 11, 2017
40
NCT04049175
Not yet recruiting
Not yet recruiting
Efficacy and Safety of CHF 6532 in Patients With Uncontrolled Severe Eosinophilic Asthma
Conditions: Asthma; Eosinophilic
Intervention: Treatment A, Treatment B, Treatment C, Treatment D
Conditions: Asthma; Eosinophilic
Intervention: Treatment A, Treatment B, Treatment C, Treatment D
August 8, 2019
41
NCT04046939
Recruiting
Recruiting
Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma
Conditions: Eosinophilic Asthma; Asthma
Intervention: Low-dose Dexpramipexole, Mid-dose Dexpramipexole, High-dose Dexpramipexole, Placebo Oral Tablet
Conditions: Eosinophilic Asthma; Asthma
Intervention: Low-dose Dexpramipexole, Mid-dose Dexpramipexole, High-dose Dexpramipexole, Placebo Oral Tablet
August 15, 2019
42
NCT03976310
Recruiting
Recruiting
CT Air-trapping for the Early Identification of Benralizumab Responders Among Eosinophilic Asthma Patients
Conditions: Asthma
Intervention: 48 Weeks Of Benralizumab, Computed Tomography
Conditions: Asthma
Intervention: 48 Weeks Of Benralizumab, Computed Tomography
June 20, 2019
43
NCT03907137
Recruiting
Recruiting
Utilisation of Benralizumab in the Clinical Practise in Severe Eosinophilic Asthma Patients in Switzerland
Conditions: Severe Eosinophilic Asthma
Conditions: Severe Eosinophilic Asthma
August 7, 2019
44
NCT03833141
Recruiting
Recruiting
Patient Reported Outcomes in Adults With Severe Eosinophilic Asthma on Benralizumab.
Conditions: Severe Eosinophilic Asthma
Intervention: Survey Administration
Conditions: Severe Eosinophilic Asthma
Intervention: Survey Administration
June 4, 2019
45
NCT03739320
Recruiting
Recruiting
A Study on the Effect of Mepolizumab Therapy on Daily Physical Activity of Patients With Severe Eosinophilic Asthma
Conditions: Severe Eosinophilic Asthma
Intervention: Mepolizumab 100 MG Injection [Nucala]
Conditions: Severe Eosinophilic Asthma
Intervention: Mepolizumab 100 MG Injection [Nucala]
November 8, 2018
46
NCT03733535
Recruiting
Recruiting
Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI
Conditions: Asthma; Eosinophilic
Intervention: Benralizumab, 129 Xenon
Conditions: Asthma; Eosinophilic
Intervention: Benralizumab, 129 Xenon
April 23, 2019
47
NCT03652376
Not yet recruiting
Not yet recruiting
Impact of Benralizumab Treatment on Circulating Dendritic Cells in Patients With Eosinophilic Asthma
Conditions: Severe Eosinophilic Asthma
Intervention: Benralizumab
Conditions: Severe Eosinophilic Asthma
Intervention: Benralizumab
August 27, 2018
48
NCT03469934
Completed
Completed
Proof of Concept Study to Investigate ANB020 Activity in Adult Patients With Severe Eosinophilic Asthma
Conditions: Eosinophilic Asthma
Intervention: ANB020, Placebo
Conditions: Eosinophilic Asthma
Intervention: ANB020, Placebo
January 30, 2019
49
NCT03453021
Completed
Completed
Effect of Mepolizumab on Decrease of Systemic Corticosteroids in Patients With Severe Eosinophilic Asthma
Conditions: Asthma; Eosinophilic
Intervention: Mepolizumab
Conditions: Asthma; Eosinophilic
Intervention: Mepolizumab
October 1, 2018
50
NCT03052725
Terminated
Terminated
A Study of Reslizumab in Patients 12 Years of Age and Older With Severe Eosinophilic Asthma
Conditions: Eosinophils, Asthma
Intervention: Reslizumab
Conditions: Eosinophils, Asthma
Intervention: Reslizumab
March 19, 2019
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In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
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97-h-0197
ia0006
actg 076
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It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
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Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
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Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
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Interventions
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Conditions
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lupus
heart attack
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risk factors for breast cancer
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Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
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does not assign specific interventions to the participants of the study.
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Records describing the procedure for obtaining an experimental drug or device for patients who
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Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.