Search results for SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Nephritis - ICH GCP - Clinical Trials Registry

ICH GCP | Clinical Trials Registry

Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Nephritis



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NCTID/Status
Study
Last Changed
1
NCT03580291
Not yet recruiting
Human Umbilical Cord Mesenchymal Stem Cells Treatment for Lupus Nephritis (LN)
Conditions: Lupus Nephritis
Intervention: Mesenchymal Stem Cells, Mycophenolate Mofetil, Placebo Of Mesenchymal Stem Cells, Placebo Of Mycophenolate Mofetil
July 9, 2018
2
NCT01470183
Completed
Lupus Nephritis Biomarker Study: Baseline Characteristics of Patients
Conditions: Lupus Nephritis
February 5, 2014
3
NCT03001973
Recruiting
High Quality Evidence of Chinese Lupus Nephritis (HELP)
Conditions: Lupus Nephritis
Intervention: No Intervention
January 20, 2019
4
NCT02547922
Active, not recruiting
Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Anifrolumab, Placebo
October 7, 2019
5
NCT03664908
Recruiting
Detection of Anti-glomerular Basement Membrane Antibodies (Anti-GBM): a Promising Biomarker for Lupus Nephritis (LN)?
Conditions: Lupus Nephritis
Intervention: Detection Of Circulating Anti-GBM Antibodies (using Chemiluminescence Method And Indirect Immunofluorescence (IIF) Method).
September 6, 2018
6
NCT02936375
Recruiting
The Iguratimod Effect on Lupus Nephritis (IGeLU)
Conditions: Lupus Nephritis
Intervention: Iguratimod, Cyclophosphamide, Azathioprine, Steroids
December 18, 2018
7
NCT03610516
Recruiting
Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.
Conditions: Lupus Nephritis
Intervention: CFZ533, Placebo
October 29, 2019
8
NCT02630628
Recruiting
Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Tacrolimus, Mycophenolate Mofetil
September 26, 2019
9
NCT01673295
Unknown status
RING - Rituximab for Lupus Nephritis With Remission as a Goal
Conditions: Lupus Nephritis
Intervention: RTX Infusions, Standard Of Care
May 27, 2015
10
NCT01539902
Unknown status
Phase 2 Study of Human Umbilical Cord Derived Mesenchymal Stem Cell for the Treatment of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Human Umbilical Cord Derived MSCs, Cyclophosphamide
March 5, 2012
11
NCT04145687
Not yet recruiting
Metformin In Prevention of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Metformin
October 29, 2019
12
NCT00908986
Withdrawn
Open Label Pilot Trial of Rituximab in Lupus Membranous Nephritis
Conditions: Lupus Nephritis
Intervention: Rituximab
May 13, 2015
13
NCT03859570
Not yet recruiting
Pentoxifylline in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Pentoxifylline, Placebos
March 5, 2019
14
NCT02453997
Unknown status
Mycophenolic Acid Pharmacokinetics and Pharmacogenomics in Lupus Nephritis
Conditions: Lupus Nephritis
June 21, 2017
15
NCT04146220
Completed
Efficacy of Lower Dose Prednisolone in the Induction of Remission of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Prednisolone
October 30, 2019
16
NCT02949349
Completed
Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Mycophenolate Mofetil, Azathioprine, Prednisolone
March 1, 2017
17
NCT02457221
Completed
A Study to Compare the Efficacy and Safety of Tacrolimus Capsules and Cyclophosphamide Injection in Treatment of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Tacrolimus Capsules, Cyclophosphamide Injections, Prednisone
October 8, 2019
18
NCT03958851
Not yet recruiting
Renal Resistive Index as a Marker of Severity and Treatment Outcomes in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Doppler Ultrasonography Of Renal Arteries, Renal Biopsy, Kidney Function Tests, The 24-hour Urine Protein Test, Complete Blood Counting (CBC)
May 22, 2019
19
NCT00876616
Completed
Assess the Efficacy and Safety of Multi-target Therapy in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Tacrolimus+Mycophenolate Mofetil, Cyclophosphamide
August 28, 2013
20
NCT03180021
Active, not recruiting
Dynamic Imaging of Variation in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: MRI
October 18, 2019
21
NCT03920059
Recruiting
Fixed-dose Versus Concentration-controlled Mycophenolate Mofetil for the Treatment of Active Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Mycophenolate Mofetil
April 17, 2019
22
NCT03458156
Active, not recruiting
Umbilical Cord Mesenchymal Stem Cell Transplantation for Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: SLE Group, LN Group, The Control Group
March 8, 2018
23
NCT03943147
Recruiting
An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: BMS-986165, Placebo
October 4, 2019
24
NCT02226341
Recruiting
ACTHar in the Treatment of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: CellCept, ACTHar Gel, ACTHar Gel
March 17, 2016
25
NCT01646736
Unknown status
Efficacy and Safety of Tripterygium Wilfordii in Patients With Lupus Nephritis
Conditions: Nephritis, Lupus
Intervention: Tripterygium Wilfordii Hook F, Cyclophosphamide, GC
July 19, 2012
26
NCT03174587
Completed
Evaluate the Safety of CS20AT04 Inj. in Subjects With Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Allogenic Bone Marrow Derived Mesenchymal Stem Cells
November 18, 2019
27
NCT00659217
Unknown status
Effect of Mesenchymal Stem Cell Transplantation for Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Mesenchymal Stem Cell
April 14, 2008
28
NCT03054545
Unknown status
Iguratimod as Treatment for Refractory Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Iguratimod
February 23, 2017
29
NCT03385564
Recruiting
An Exploratory Maintenance Trial of BI 655064 in Patients With Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: BI 655064, Placebo
December 10, 2019
30
NCT03214731
Recruiting
Efficacy and Safety of Artesunate Plus Standard of Care in Active Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Artesunate, Placebo
January 20, 2019
31
NCT01580865
Completed
Comparison Between Tacrolimus (TAC) and Mycophenolate Mofetil (MMF) for Induction of Remission in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Tacrolimus Vs. Mycophenolate Mofetil For Induction Therapy In Lupus Nephritis
September 10, 2018
32
NCT03200002
Completed
Cyclophosphamide Versus Mycophenolate Mofetil in Lupus Nephritis
Conditions: To Compare the Effects of Mycophenolate Mofetil With Cyclophosphamide in Neplaese Lupus Nephritis Patients
Intervention: Cyclophosphamide, Mycophenolate Mofetil
June 26, 2017
33
NCT04181762
Not yet recruiting
Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Secukinumab
November 27, 2019
34
NCT00539799
Withdrawn
Steroids in the Maintenance of Remission of Proliferative Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Prednisolone, Placebo
May 28, 2008
35
NCT00573157
Terminated
The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Atacicept, Mycophenolate Mofetil, Placebo, Corticosteroids
February 22, 2016
36
NCT01299922
Withdrawn
Clinical Trial Treatment in Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Cyclosporine +mycophenolic Acid+prednison, Mycophenolic Acid + Prednison
February 26, 2015
37
NCT01015456
Terminated
The Efficacy of Enteric-coated Mycophenolate Sodium (EC-MPS) (Myfortic) in The Treatment of Relapse or Resistant Proliferative Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Mycophenolate Sodium, Cyclophosphamide
October 9, 2014
38
NCT02260934
Completed
Rituximab and Belimumab for Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Rituximab, Cyclophosphamide, Prednisone, Methylprednisolone, Diphenhydramine, Acetaminophen, Rituximab, Cyclophosphamide, Prednisone, Methylprednisolone, Diphenhydramine, Acetaminophen, Belimumab
April 5, 2019
39
NCT02770170
Active, not recruiting
Dose Finding, Efficacy and Safety of BI 655064 in Patients With Active Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: BI 655064 Dose 1, BI 655064 Dose 2, BI 655064 Dose 3, Placebo
October 1, 2019
40
NCT01342016
Terminated
A Study to Compare the Efficacy and Safety of Tacrolimus Capsules With Leflunomide Tablets in Lupus Nephritis Patients
Conditions: Lupus Nephritis
Intervention: Tacrolimus Capsule, Tacrolimus Placebo, Leflunomide Tablet, Leflunomide Placebo, Prednisone
October 15, 2014
41
NCT02645565
Completed
Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Cyclophosphamide, Azathioprine, Methylprednisolone
March 2, 2017
42
NCT00709722
Completed
Safety and Efficacy on Deoxyspergualin (NKT-01) in Patients With Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: NKT-01
November 13, 2016
43
NCT02550652
Active, not recruiting
A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)
Conditions: Lupus Nephritis
Intervention: Mycophenolate Mofetil/Mycophenolic Acid, Obinutuzumab, Placebo, Methylprednisolone, Prednisone
October 29, 2019
44
NCT01893658
Withdrawn
Xolair (Omalizumab) for Treatment of Drug-induced Acute Tubulointerstitial Nephritis (AIN)
Conditions: Acute Interstitial Nephritis
Intervention: Omalizumab, Prednisone
December 4, 2018
45
NCT01639339
Active, not recruiting
Efficacy and Safety of Belimumab in Patients With Active Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Placebo Plus Standard Therapy, Belimumab 10 Mg/kg Plus Standard Therapy, Standard Therapy
December 6, 2019
46
NCT01203709
Completed
Low-dose Combination of Mycophenolate Mofetil (MMF) and Tacrolimus (Tac) for Refractory Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Low Dose Combination Of MMF And Tac
March 3, 2014
47
NCT02256150
Completed
A Study to Evaluate the Efficacy and Safety of Mizoribine in the Treatment of Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Mizoribine (MZR), Cyclophosphamide (CTX)
June 5, 2019
48
NCT02081183
Terminated
A Study to Evaluate Efficacy of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: Mycophenolate Mofetil (MMF), Cyclophosphamide, Maintenance Phase, Cyclophosphamide, Induction Phase, Prednisone
June 17, 2014
49
NCT02176486
Terminated
Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Ixazomib in Lupus Nephritis (LN)
Conditions: Lupus Nephritis
Intervention: Ixazomib, Placebo
January 11, 2019
50
NCT01930890
Terminated
BIIB023 Long-Term Extension Study in Subjects With Lupus Nephritis
Conditions: Lupus Nephritis
Intervention: BIIB023, Mycophenolate Mofetil, Oral Corticosteroids
November 22, 2016

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

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By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

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By Category

Dietary
Supplements

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By Category

Sponsor/
Collaborators

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By Category

Locations

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By Category