ICH GCP | Clinical Trials Registry

Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Urinary Bladder Neoplasms [STUDY:DISEASE] )



1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Last


#
NCTID/Status
Study
Last Changed
1
NCT02430623
Recruiting
Irreversible Electroporation(IRE) For Unresectable Urinary Bladder Neoplasms
Conditions: Urinary Bladder Neoplasms
Intervention: Irreversible Electroporation (IRE), NanoKnife
March 27, 2016
2
NCT02760953
Not yet recruiting
TURBt With Adjuvant Cryoablation to Treat Bladder Cancer
Conditions: Urinary Bladder Neoplasms
Intervention: Cryoablation, Epirubicin
October 17, 2017
3
NCT02857634
Completed
Confocal Microscopy Dual Band in the Management of Bladder Cancer
Conditions: Urinary Bladder Neoplasm
Intervention: Cellvizio Dual Band
October 30, 2018
4
NCT04029948
Recruiting
Laser vs. Electorsurgical Enbloc Resection of Bladder Tumours
Conditions: Urinary Bladder Neoplasm
Intervention: Laser En Bloc Resection Of Bladder Tumor, Electro-surgical En Bloc Resection Of Bladder Tumor
July 24, 2019
5
NCT02311101
Completed
Phase I Mitomycin Combined With Bacillus Calmette-Guérin (BCG) for Bladder Cancer
Conditions: Urinary Bladder Neoplasm
Intervention: Mitomycin C
December 1, 2015
6
NCT02957370
Recruiting
Molecular Biosensors for Detection of Bladder Cancer
Conditions: Urinary Bladder Neoplasms
October 10, 2018
7
NCT03258593
Recruiting
Durvalumab and Vicinium in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)
Conditions: Urinary Bladder Neoplasms
Intervention: Durvalumab, Vicinium
August 16, 2019
8
NCT02805608
Active, not recruiting
uPAR PET/CT and FDG PET/MRI for Preoperative Staging of Bladder Cancer
Conditions: Urinary Bladder Neoplasms
Intervention: Injection Of 68Ga-NOTA-AE105, Injection Of 18F-FDG, Positron Emission Tomography And CT, Positron Emission Tomography And MRI
April 9, 2018
9
NCT02489890
Active, not recruiting
CIK in Treating Patients With Bladder Cancer
Conditions: Urinary Bladder Neoplasms
Intervention: Cytokine-induced Killer Cells
February 18, 2016
10
NCT03459846
Recruiting
A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU)
Conditions: Urinary Bladder Neoplasms
Intervention: Durvalumab, Olaparib, Placebo
July 17, 2019
11
NCT01435356
Terminated
Safety and Efficacy Study of MAGE-A3 + AS-15 in Patients With Muscle-invasive Bladder Cancer After Cystectomy
Conditions: Urinary Bladder Neoplasms
Intervention: RecMAGE-A3 + AS15 ASCI, Placebo
January 8, 2019
12
NCT03977831
Recruiting
Study Comparing Open Radical Cystectomy With Robot-assisted Cystectomy in Patients With Bladder Cancer
Conditions: Urinary Bladder Neoplasms
Intervention: Radical Cystectomy
June 25, 2019
13
NCT00625664
Completed
Larotaxel + Cisplatin Versus Gemcitabine + Cisplatin in First Line Treatment of Locally Advanced/Metastatic Urothelial Tract or Bladder Cancer
Conditions: Urinary Bladder Neoplasms
Intervention: Larotaxel (XRP9881), Gemcitabine, Cisplatin
April 6, 2016
14
NCT02555163
Active, not recruiting
Laser En Bloc Resection Of Bladder Tumor (HoLERBT) VS. Conventional Transurethral Resection Of Bladder Tumors (cTURBT)
Conditions: Bladder Cancer
Intervention: HoLERBT, CTURBT
March 8, 2019
15
NCT04040725
Not yet recruiting
Rogaratinib for BCG Refractory High Risk Non-Muscle Invasive Bladder Cancer With FGFR1/2 Overexpression
Conditions: Bladder Cancer
Intervention: Rogaratinib
July 31, 2019
16
NCT03715660
Recruiting
Xpert Bladder Cancer Monitor; Prospective, Single, Tertiary-care Center Implementation Study
Conditions: Bladder Cancer
Intervention: Xpert Bladder Cancer Monitor
October 21, 2018
17
NCT03982797
Recruiting
Treatment of High-risk Non-muscle Invasive Bladder Cancer With IMUNO BGC Moreau RJ as Prophylaxis
Conditions: Bladder Cancer
Intervention: Instillation Of IMUNO BCG Moreau RJ
June 10, 2019
18
NCT02560038
Terminated
Trial of Paclitaxel Plus Gemcitabine and Cisplatin in Bladder Cancer
Conditions: Urinary Bladder Neoplasms
Intervention: Gemcitabine, Paclitaxel, Cisplatin
November 2, 2018
19
NCT03756207
Recruiting
Multidisciplinary Bladder-preservation Therapy for Bladder Cancer
Conditions: Bladder Cancer
Intervention: Multidisciplinary Bladder-preservation Therapy
November 26, 2018
20
NCT02053662
Unknown status
Biomarker Identification for Bladder Cancer Patients
Conditions: Bladder Cancer
Intervention: Sample Collection
April 12, 2017
21
NCT04060459
Recruiting
Paclitaxel-binding Albumin and Cisplatin as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer
Conditions: Bladder Cancer
Intervention: Paclitaxel-binding Albumin
August 15, 2019
22
NCT02662062
Recruiting
Pembrolizumab With Chemoradiotherapy as Treatment for Muscle Invasive Bladder Cancer
Conditions: Bladder Cancer
Intervention: Pembrolizumab, Cisplatin, Radiotherapy
July 1, 2019
23
NCT03029663
Completed
Complications of Transurethral Resection of the Bladder Tumour
Conditions: Bladder Cancer
Intervention: Transurethral Resection Of The Bladder Tumour
December 27, 2018
24
NCT02695771
Unknown status
The Bladder Instillation Comparison Study
Conditions: Urinary Bladder Neoplasms
Intervention: Mitomycin C, Gemcitabine
April 6, 2017
25
NCT02885974
Recruiting
Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer
Conditions: Bladder Cancer
Intervention: Celecoxib, Gemcitabine, Cisplatin
August 15, 2018
26
NCT03150836
Withdrawn
Radiation Therapy and Durvalumab, With or Without Tremelimumab, in Patients With Bladder Cancer
Conditions: Bladder Cancer
Intervention: Durvalumab, Tremelimumab, Radiation Therapy
October 17, 2017
27
NCT01567462
Completed
PlasmaKinetic (PK) Button Vaporization Electrode for Treatment of Bladder Tumors
Conditions: Bladder Cancer
Intervention: Monopolar Electrocautery Loop In Transurethral Resection Of Bladder Tumors, PK Button Vaporization Electrode In Transurethral Resection Of Bladder Tumors
November 9, 2017
28
NCT03773666
Recruiting
A Feasibility Study of Durvalumab +/- Oleclumab as Neoadjuvant Therapy for Muscle-invasive Bladder Cancer (BLASST-2)
Conditions: Muscle Invasive Bladder Cancer
Intervention: Durvalumab, Oleclumab
February 22, 2019
29
NCT00871754
Active, not recruiting
Molecular Analysis Of Bladder Cancer
Conditions: Bladder Cancer; Bladder Neoplasms
August 13, 2019
30
NCT02197897
Recruiting
Evaluation the Treatment of Tamoxifen of Low/Intermediate Risk Bladder Tumors
Conditions: Bladder Cancer
Intervention: Tamoxifen Citrate
May 8, 2018
31
NCT02605863
Terminated
Enzalutamide for Bladder Cancer Chemoprevention
Conditions: Bladder Cancer
Intervention: Enzalutamide
September 5, 2018
32
NCT03998579
Not yet recruiting
Physical Rehabilitation Among Patients Undergoing Radical Cystectomy Due to Urinary Bladder Cancer
Conditions: Urinary Bladder Cancer
Intervention: The CanMoRe Programme, Home Exercise
June 25, 2019
33
NCT01581723
Unknown status
Clinical Trial Using Bipolar Technology for Transurethral Resection of Bladder Tumor
Conditions: Urinary Bladder Tumor
Intervention: Monopolar Diathermy, Bipolar Diathermy
February 2, 2015
34
NCT01956253
No longer available
Single Subject Neratinib in Bladder Cancer (NRR)
Conditions: Bladder Cancer
Intervention: Neratinib
March 10, 2017
35
NCT02324582
Recruiting
MK-3475/BCG in High Risk Superficial Bladder Cancer
Conditions: Bladder Cancer
Intervention: Intravenous MK-3475/ Intravesical BCG
July 15, 2019
36
NCT01697306
Completed
The Impact of Intravesical Gemcitabine and 1/3 Dose Bacillus Calmette-Guerin on the Quality of Life in Superficial Bladder Cancer
Conditions: Bladder Cancer
Intervention: Gemcitabine 2 G, BCG Vaccine
September 27, 2012
37
NCT01498172
Completed
BCG Modulation of the recMAGE-A3 + AS15 ASCI Response in the Treatment of Non Muscle Invasive Bladder Cancer (NMIBC) Patients
Conditions: Bladder Cancer
Intervention: MAGE-A3 ASCI, BCG
February 3, 2015
38
NCT03978624
Recruiting
Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer
Conditions: Bladder Cancer
Intervention: Pembrolizumab, Entinostat
July 17, 2019
39
NCT00848627
Unknown status
Screening for Bladder Cancer
Conditions: Bladder Cancer
Intervention: Specimen And Questionnaires Only
December 9, 2010
40
NCT01827943
Completed
Phase II Evaluating Efficacy of Temsirolimus in 2 Line Therapy for Patients With Advanced Bladder Cancer
Conditions: Relapsed Bladder Cancer
Intervention: TORISEL
September 29, 2017
41
NCT02287701
Completed
Exploratory Investigation of Advanced PET/MRI Metrics for Bladder Cancer Characterization
Conditions: Bladder Cancer
Intervention: PET/MRI
August 10, 2017
42
NCT03534492
Recruiting
Durvalumab Plus Olaparib Administered Prior to Surgery of Resectable Urothelial Bladder Cancer (NEODURVARIB)
Conditions: Bladder Cancer
Intervention: Durvalumab, Olaparib
February 6, 2019
43
NCT00772018
Completed
Quality of Life and Symptom Management in Patients With Bladder Cancer
Conditions: Bladder Cancer
February 1, 2012
44
NCT02993211
Recruiting
Transurethral En Bloc Versus Standard Resection of Bladder Tumour
Conditions: Bladder Cancer
Intervention: Bipolar Transurethral Standard Resection, Bipolar Transurethral En Bloc Resection
November 19, 2018
45
NCT02371447
Active, not recruiting
VPM1002BC in Recurrent Non-muscle Invasive Bladder Cancer
Conditions: Bladder Cancer
Intervention: VPM1002BC
November 6, 2018
46
NCT01801644
Completed
Neoadjuvant Chemotherapy in Locally Advanced Bladder Cancer
Conditions: Bladder Cancer
Intervention: Gemcitabine Plus Cisplatin
February 28, 2013
47
NCT03914001
Recruiting
Comprehensive Multiparametric Magnetic Resonance Imaging After Transurethral Resection of Non Muscle-invasive Bladder Tumor; Can it Replace Second Look Biopsy? A Prospective Study
Conditions: Bladder Cancer
Intervention: MpMRI, Second Look TURBT
April 10, 2019
48
NCT00744744
Completed
Health-Related Quality of Life in Patients With Bladder Cancer
Conditions: Bladder Cancer
Intervention: Informational Intervention, Questionnaire Administration, Management Of Therapy Complications, Psychosocial Assessment And Care, Quality-of-life Assessment
February 1, 2012
49
NCT00981656
Active, not recruiting
Radiation Therapy and Chemotherapy in Treating Patients With Stage I Bladder Cancer
Conditions: Bladder Cancer
Intervention: Cisplatin, Fluorouracil, Mitomycin C
December 21, 2017
50
NCT03254888
Not yet recruiting
Autophagy Bladder Cancer
Conditions: Bladder Cancer
July 4, 2019

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Last


Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

Alphabetic (A-Z)
By Category

Dietary
Supplements

Alphabetic (A-Z)
By Category

Sponsor/
Collaborators

Alphabetic (A-Z)
By Category

Locations

Alphabetic (A-Z)
By Category