Search results for SEARCH[Study] TILT[Study:StudyFirstPostDate] ALL - ICH GCP - Clinical Trials Registry

ICH GCP | Clinical Trials Registry

Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] ALL



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#
NCTID/Status
Study
Last Changed
51
NCT04196530
Recruiting
BDB001-102 Open Label Dose Escalation Combination w Atezolizumab
Conditions: Tumor, Solid
Intervention: BDB001, Atezolizumab
December 11, 2019
52
NCT04196517
Not yet recruiting
PALS for Nutrition Education
Conditions: Nutrition Disorders
Intervention: Educational Tool, PALS, WebMD
December 10, 2019
53
NCT04196504
Not yet recruiting
Prevalence of Echocardioghraphic and ECG Changes in Patients With Acute Pancreatitis and Its Impact on Outcome.
Conditions: Acute Pancreatitis
Intervention: Echocardiograghy, ECG
December 10, 2019
54
NCT04196491
Not yet recruiting
A Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (NDMM) (KarMMa-4)
Conditions: Multiple Myeloma
Intervention: Bb2121 Carfilzomib, Fludarabine, Cyclophosphamide, Lenalidomide
December 10, 2019
55
NCT04196478
Not yet recruiting
Role of Color Doppler Ultrasonography in Assessment of Vascular Access Surveillance in Hemodialysis Patients.
Conditions: Arteriovenous Fistula
Intervention: Doppler Ultrasound
December 10, 2019
56
NCT04196465
Recruiting
Phase II Study of Neoadjuvant Immune Checkpoint Inhibitor in Patients With Resectable Gastrointestinal Cancers
Conditions: Subjects With Resectable and Localized Gastric Cancer; Subjects With Resectable Esophageal Cancer or Liver Cancer; Subjects With Resectable Liver Cancer
Intervention: IMC-001
December 10, 2019
57
NCT04196452
Active, not recruiting
A Retrospective Observational Study on the Long-term Effects of Ipilimumab-treated Pediatric Participants in the Dutch Melanoma Treatment Registry (DMTR)
Conditions: Melanoma
Intervention: Ipilimumab
December 11, 2019
58
NCT04196439
Recruiting
Continuous Epidural Analgesia Versus Continuous Supra-Inguinal Fascia Iliaca Block in Total Hip Replacement Surgery
Conditions: Postoperative Pain
Intervention: Continuous Epidural Analgesia, Supra-inguinal Fascia Iliaca Compartment Block
December 10, 2019
59
NCT04196426
Completed
Nutrition Education to Promote Calcium Intake Among 30-65 Year-old Women in Vietnam
Conditions: Calcium Intake
Intervention: Nutrition Education Intervention About Osteoporosis And Calcium
December 10, 2019
60
NCT04196413
Not yet recruiting
GD2 CAR T Cells in DiffuseIntrinsicPontine Gliomas(DIPG) & Spinal DiffuseMidline Glioma(DMG)
Conditions: Glioma of Spinal Cord; Glioma of Brainstem
Intervention: GD2 CAR T Cells, Fludarabine, Cyclophosphamide
December 10, 2019
61
NCT04196400
Enrolling by invitation
The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery.
Conditions: Hypospadias
Intervention: Steroid Betamethasone
December 10, 2019
62
NCT04196387
Completed
Antimicrobial Resistance Rate In Escherichia Coli And Klebsiella Pneumonia : A Retrospective Study
Conditions: Antibiotic Reaction
Intervention: Urine Culture
December 10, 2019
63
NCT04196374
Not yet recruiting
Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts
Conditions: Seemingly Healthy; Genetic Predisposition to Disease
Intervention: Genomic Sequencing
December 10, 2019
64
NCT04196361
Completed
Ultrasonography for Prediction of Extubation Success: a Holistic Approach
Conditions: Exutbation Failure; Mechanical Ventilation
Intervention: Ultrasound
December 10, 2019
65
NCT04196348
Recruiting
Surgical Innovation for Diabetes Treatment
Conditions: Obesity; Diabetes Mellitus, Type 2
Intervention: Short BPL RYGB, Long BPL RYGB
December 10, 2019
66
NCT04196335
Not yet recruiting
I Can sEe Left Atrial Appendage (ICELAA) Clinical Study
Conditions: Efficacy, Self; Safety Issues
Intervention: Intra-procedural Intracardiac Echocardiography
December 10, 2019
67
NCT04196322
Completed
Hyperglycemia as a Prognostic Factor In Acute Ischemic Stroke Patients
Conditions: Acute Ischemic Stroke Patients
Intervention: Observational Study
December 10, 2019
68
NCT04196309
Recruiting
Effect of LOW-molecular-weight Heparin in Reducing Radial Artery Occlusion Rate After Transradial Coronary Catheterization
Conditions: Arterial Occlusion
Intervention: Low Molecular Weight Heparin
December 10, 2019
69
NCT04196296
Completed
Treatment Seeking for Social Anxiety
Conditions: Social Anxiety
Intervention: Psychoeducation, Motivation
December 10, 2019
70
NCT04196283
Not yet recruiting
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Conditions: Advanced Solid Tumors Cancer
Intervention: ABBV-368, Tilsotolimod, Nab-paclitaxel, ABBV-181
December 10, 2019
71
NCT04196270
Not yet recruiting
The Minimal Effective Volume (MEV90) of Ropivacaine 0.75% for Ultrasound-guided Transmuscular Quadratus Lumborum Block
Conditions: Percutaneous Nephrolithotomy
Intervention: Ropivacaine Injection
December 10, 2019
72
NCT04196257
Not yet recruiting
BP1001-A in Patients With Advanced or Recurrent Solid Tumors
Conditions: Solid Tumor, Adult; Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Endometrial Cancer; Peritoneal Cancer; Solid Tumor
Intervention: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide), BP1001-A (Liposomal Grb2 Antisense Oligonucleotide) With Paclitaxel
December 10, 2019
73
NCT04196244
Not yet recruiting
Intravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal Function
Conditions: Acute Abdomen; Radiocontrast Nephropathy
Intervention: Abdominal Or Body CT With Intravenous Contrast, Abdominal Or Body CT Without Intravenous Contrast (native CT)
December 11, 2019
74
NCT04196231
Recruiting
Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND)
Conditions: Type 2 Diabetes
Intervention: IDegLira, IGlarLixi, Insulin/Canaglifozin, Insulin/Dapaglifozin, Insulin/Empaglifozin, Basal Bolus
December 11, 2019
75
NCT04196218
Not yet recruiting
Driving After Shoulder Surgery
Conditions: Shoulder
Intervention: Driving Simulator
December 11, 2019
76
NCT04196205
Recruiting
Anti-CD19 CAR-T Cells for Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphomas
Conditions: Acute Lymphoblastic Leukemia ,Lymphomas
Intervention: Anti-CD19 CAR-T
December 11, 2019
77
NCT04196192
Not yet recruiting
Diagnostic Accuracy of Procalcitonin for the Detection of Bacterial Infections in Young Infants.
Conditions: Sepsis
December 10, 2019
78
NCT04196179
Not yet recruiting
ANG-3070 in Healthy Adult Participants
Conditions: Safety
Intervention: ANG3070, Placebo Oral Capsule
December 11, 2019
79
NCT04196166
Completed
Routine Preoperative Evaluation in Surgical Patient
Conditions: Orthopedic Disorder
Intervention: Preoperative Blood Tests
December 11, 2019
80
NCT04196153
Recruiting
A Comparison of Pedicle Screws Placement Accuracy in Thoracolumbar Spine Using Two Guidance Techniques Which Are O-arm Navigation and Standard Cervical Distractor Screws
Conditions: Pedicle Screws; Surgery, Computer-Assisted/Adverse Effects; Bone Screws; Imaging, Three-Dimensional/Methods
Intervention: Pedicle Screws Instrumentation
December 10, 2019
81
NCT04196140
Not yet recruiting
Pivotal Omnipod Horizon™ Automated Glucose Control System
Conditions: Type 1 Diabetes Mellitus
Intervention: Omnipod Horizon™ Automated Glucose Control System
December 10, 2019
82
NCT04196127
Recruiting
Jaw Muscle Function in Patients With Tension-type Headache
Conditions: Headache Disorders; Tension-Type Headache
Intervention: Bite Force Testing
December 10, 2019
83
NCT04196114
Not yet recruiting
Study on Feasibility of Stimulation on the Lumbar Part of the Spinal Cord to Improve Mobility Recovery in Patients With Sub-acute Spinal Cord Injury
Conditions: Spinal Cord Injury
Intervention: STIMO-2 Device Implantation
December 10, 2019
84
NCT04196101
Recruiting
A Study to Assess EDP-938 for the Treatment of Acute Upper Respiratory Tract Infection With Respiratory Syncytial Virus in Adult Subjects
Conditions: Respiratory Syncytial Virus
Intervention: EDP-938, Placebo
December 10, 2019
85
NCT04196088
Withheld
[Trial of device that is not approved or cleared by the U.S. FDA]
Conditions: 
December 10, 2019
86
NCT04196075
Recruiting
The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer
Conditions: Squamous Cell Carcinoma of Esophagus
Intervention: Andrographis Paniculata
December 10, 2019
87
NCT04196062
Not yet recruiting
EndoMaster EASE System for Treatment of Colorectal Lesions
Conditions: Colonic Neoplasms
Intervention: EndoMASTER EASE Robotic System For ESD
December 10, 2019
88
NCT04196049
Completed
Removal of Massive Subretinal Organized Blood Clot With Fragmatome
Conditions: Age-Related Macular Degeneration
Intervention: Fragmatome
December 10, 2019
89
NCT04196036
Recruiting
Day 3 Fresh Transfer Followed by Day 3 or Day 5 Vitrification of Supernumerary Embryos
Conditions: Subfertility
Intervention: Day Of Vitrification
December 10, 2019
90
NCT04196023
Active, not recruiting
Ca:Mg Ratio and Cognitive Function
Conditions: Cognitive Function
Intervention: Magnesium Glycinate, Placebo
December 10, 2019
91
NCT04196010
Not yet recruiting
G-CSF and Continuous Infusion Chemotherapy (CI-GCLAM) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms
Conditions: Myeloid Neoplasm; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia
Intervention: Cladribine, Cytarabine, Granulocyte Colony-Stimulating Factor, Mitoxantrone
December 10, 2019
92
NCT04195997
Not yet recruiting
Multi-center Application of Bivalirudin in Left Atrial Appendage Occlusion
Conditions: Evaluate the Safety and Efficacy of Bivalirudin in Decreasing Bleeding Risk
Intervention: Bivalirudin, Heparin
December 10, 2019
93
NCT04195984
Not yet recruiting
Mi-thos® Transcatheter Mitral Valve Replacement Study
Conditions: Mitral Valve Regurgitation
Intervention: Mi-thos® Valve And Transapical Delivery System
December 10, 2019
94
NCT04195971
Not yet recruiting
Dual Arterial Phase Liver CT in Patients With Suspected Portal Hypertension
Conditions: HCC; Cirrhosis, Liver
Intervention: Liver CT
December 10, 2019
95
NCT04195958
Not yet recruiting
A Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants With Moderate to Severe Allergic Asthma
Conditions: Moderate-to-severe Allergic Asthma
Intervention: Omalizumab, Placebo
December 10, 2019
96
NCT04195945
Not yet recruiting
CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients
Conditions: Acute Myeloid Leukemia; Myeloid Neoplasm
Intervention: Liposome-encapsulated Daunorubicin-Cytarabine, Cladribine, Cytarabine, Granulocyte Colony-Stimulating Factor, Mitoxantrone, Questionnaire Administration, Quality-of-Life Assessment
December 10, 2019
97
NCT04195932
Completed
Exercise as a Modulator of Immune Risk Factors for Ischemic Heart Disease
Conditions: Heart Diseases
Intervention: Exercise Training
December 10, 2019
98
NCT04195919
Not yet recruiting
The Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of Evogliptin in Hemodialysis Patients
Conditions: Hemodialysis Patients
Intervention: Evogliptin 5mg, Evogliptin 5mg
December 10, 2019
99
NCT04195906
Not yet recruiting
Phase 3 Randomized, Double-Blind, Placebo Controlled Study of SNF472 for Calciphylaxis
Conditions: Calciphylaxis; CUA; Calcific Uremic Arteriolopathy
Intervention: Experimental: SNF472, Placebo Comparator: Placebo, Experimatenl SNF472 (Open-label)
December 10, 2019
100
NCT04195893
Recruiting
Performance of Two Daily Disposable Contact Lenses When Frequent Replacement Lens Wearers Are Refit
Conditions: Myopia
Intervention: Somofilcon A, Etafilcon A
December 10, 2019

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

Alphabetic (A-Z)
By Category

Dietary
Supplements

Alphabetic (A-Z)
By Category

Sponsor/
Collaborators

Alphabetic (A-Z)
By Category

Locations

Alphabetic (A-Z)
By Category