Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Anemia
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NCTID/Status
Study
Last Changed
951
NCT03531736
Recruiting
Recruiting
T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia
Conditions: Myeloid Diseases
Intervention: Antithymocyte Globulin (Rabbit), Fludarabine, Total Body Irradiation, Cyclophosphamide, Rituxan, Allogeneic Hematopoietic Stem Cell Transplantation
Conditions: Myeloid Diseases
Intervention: Antithymocyte Globulin (Rabbit), Fludarabine, Total Body Irradiation, Cyclophosphamide, Rituxan, Allogeneic Hematopoietic Stem Cell Transplantation
June 13, 2019
952
NCT00270179
Completed
Completed
A Study to Evaluate the Effectiveness and Safety of Epoetin Alfa During the Period When One is Donating One's Own Blood Before Surgery.
Conditions: Anemia
Intervention: Epoetin Alfa
Conditions: Anemia
Intervention: Epoetin Alfa
May 17, 2011
953
NCT01418898
Unknown status
Unknown status
August 16, 2011
954
NCT02187003
Completed
Completed
Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Conditions: Anemia, Sickle Cell
Intervention: Rivipansel, Placebo
Conditions: Anemia, Sickle Cell
Intervention: Rivipansel, Placebo
December 13, 2019
955
NCT00761657
Completed
Completed
Phase 2 Study of FG-4592 in Subjects With Anemia and Chronic Kidney Disease Not Requiring Dialysis
Conditions: Chronic Kidney Disease; Anemia
Intervention: FG-4592, FG-4592, FG-4592, FG-4592, FG-4592, FG-4592, FG-4592
Conditions: Chronic Kidney Disease; Anemia
Intervention: FG-4592, FG-4592, FG-4592, FG-4592, FG-4592, FG-4592, FG-4592
January 28, 2013
956
NCT00401869
Completed
Completed
The Effect of PROCRIT (Epoetin Alfa) on Postoperative Vigor and Handgrip Strength (VIGOR Study)
Conditions: Anemia
Intervention: Epoetin Alfa
Conditions: Anemia
Intervention: Epoetin Alfa
April 5, 2010
957
NCT03565354
Recruiting
Recruiting
Efficacy of Preoperative Intravenous Iron in Anaemic Colorectal Cancer Surgical Patients
Conditions: Anemia, Iron-Deficiency; Colorectal Cancer
Intervention: Iron Isomaltoside(Monofer®)
Conditions: Anemia, Iron-Deficiency; Colorectal Cancer
Intervention: Iron Isomaltoside(Monofer®)
June 23, 2019
958
NCT00111163
Completed
Completed
Intermittent Preventive Treatment With Antimalarials in Kenyan Infants
Conditions: Malaria; Anemia
Intervention: Sulfadoxine-pyrimethamine With Artesunate, Amodiaquine With Artesunate, Chlorproguanil-dapsone
Conditions: Malaria; Anemia
Intervention: Sulfadoxine-pyrimethamine With Artesunate, Amodiaquine With Artesunate, Chlorproguanil-dapsone
September 26, 2012
959
NCT00392418
Completed
Completed
Flexible Administration of Sprinkles® in Infants and Young Children in Rural Bangladesh.
Conditions: Anemia
Intervention: Multiple Micronutrient Supplement (iron)
Conditions: Anemia
Intervention: Multiple Micronutrient Supplement (iron)
March 11, 2010
960
NCT03759353
Completed
Completed
Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy
Conditions: Iron Deficiency Anemia
Intervention: Baseline Ferritin Level, Lactoferrin, Ferrous Sulfate, Follow Up Ferritin Level
Conditions: Iron Deficiency Anemia
Intervention: Baseline Ferritin Level, Lactoferrin, Ferrous Sulfate, Follow Up Ferritin Level
November 28, 2018
961
NCT01362595
Active, not recruiting
Active, not recruiting
Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia
Conditions: Diamond Blackfan Anemia; Blackfan Diamond Syndrome; DBA; Congenital Hypoplastic Anemia; Pure Red Cell Aplasia
Intervention: Leucine
Conditions: Diamond Blackfan Anemia; Blackfan Diamond Syndrome; DBA; Congenital Hypoplastic Anemia; Pure Red Cell Aplasia
Intervention: Leucine
December 12, 2019
962
NCT00039884
Unknown status
Unknown status
Will Radiation/Chemotherapy Treatment of Cervical Cancer Work Better With Medication That May Improve Anemia?
Conditions: Anemia; Cervix Neoplasms
Intervention: NESP - Novel Erythropoiesis Stimulating Protein
Conditions: Anemia; Cervix Neoplasms
Intervention: NESP - Novel Erythropoiesis Stimulating Protein
June 23, 2005
963
NCT00270062
Completed
Completed
A Study to Evaluate the Safety of Epoetin Alfa and Its Effectiveness in Facilitating the Presurgical Collection of Blood From Anemic Patients for Possible Self-transfusion During and After Scheduled Joint Surgery.
Conditions: Anemia
Intervention: Epoetin Alfa
Conditions: Anemia
Intervention: Epoetin Alfa
May 17, 2011
964
NCT01444261
Completed
Completed
Prevention of Iron Deficiency in Breastfed Infants
Conditions: Iron Deficiency; Anemia
Intervention: Fer-in-Sol, Control
Conditions: Iron Deficiency; Anemia
Intervention: Fer-in-Sol, Control
March 29, 2017
965
NCT01772420
Recruiting
Recruiting
Lenalidomide and Eltrombopag Olamine in Treating Patients With Symptomatic Anemia in Low or Intermediate Myelodysplastic Syndrome
Conditions: Adult Myelodysplastic Syndrome; Anemia; Chronic Myelomonocytic Leukemia
Intervention: Eltrombopag Olamine, Laboratory Biomarker Analysis, Lenalidomide
Conditions: Adult Myelodysplastic Syndrome; Anemia; Chronic Myelomonocytic Leukemia
Intervention: Eltrombopag Olamine, Laboratory Biomarker Analysis, Lenalidomide
September 4, 2019
966
NCT01651416
Completed
Completed
Seasonal Malaria Chemoprevention Versus Home Management of Malaria in Children Under 5 Years in Ghana
Conditions: Malaria; Anaemia
Intervention: Artemether-lumefantrine Combination, Dihydroartemisinin Piperaquine Combination, Amodiaquine Plus Sulphadoxine-pyrimethamine Combination
Conditions: Malaria; Anaemia
Intervention: Artemether-lumefantrine Combination, Dihydroartemisinin Piperaquine Combination, Amodiaquine Plus Sulphadoxine-pyrimethamine Combination
September 17, 2015
967
NCT03286205
Withdrawn
Withdrawn
A Randomized Study to Compare the Dosing Schedule of INFeD in Anemic Patients.
Conditions: Anemia, Iron Deficiency
Intervention: IV Iron
Conditions: Anemia, Iron Deficiency
Intervention: IV Iron
June 3, 2019
968
NCT03802201
Recruiting
Recruiting
Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic Anemia
Conditions: β-thalassemia; Ineffective Erythropoiesis
Intervention: PTG-300
Conditions: β-thalassemia; Ineffective Erythropoiesis
Intervention: PTG-300
December 3, 2019
969
NCT00597584
Completed
Completed
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Epoetin Alfa Or Epoetin Beta
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Epoetin Alfa Or Epoetin Beta
March 6, 2013
970
NCT00437866
Completed
Completed
Hepcidin in Anemic Chronic Heart Failure (CHF) Patients
Conditions: Anemia; Chronic Heart Failure
Conditions: Anemia; Chronic Heart Failure
December 5, 2012
971
NCT00341055
Completed
Completed
A Study to Evaluate the Hematologic Response Rate (the Rate at Which the Hemoglobin Level Rises) of PROCRIT (Epoetin Alfa) Given at a Dose of 80,000 Units Once Weekly to Cancer Patients With Anemia Who Are Receiving Chemotherapy.
Conditions: Anemia; Cancer; Chemotherapy
Intervention: Epoetin Alfa
Conditions: Anemia; Cancer; Chemotherapy
Intervention: Epoetin Alfa
June 8, 2011
972
NCT00597753
Completed
Completed
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Epoetin Alfa
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Epoetin Alfa
February 6, 2013
973
NCT03002090
Completed
Completed
Defining the Functional Role of Iron in Aerobic Training and Physical Performance
Conditions: Iron Deficiency Without Anemia
Intervention: Iron Trained, Iron Untrained, BZKL Trained, BZKL Untrained, Placebo Trained, Placebo Untrained
Conditions: Iron Deficiency Without Anemia
Intervention: Iron Trained, Iron Untrained, BZKL Trained, BZKL Untrained, Placebo Trained, Placebo Untrained
December 20, 2016
974
NCT04091737
Recruiting
Recruiting
CSL200 Gene Therapy in Adults With Severe Sickle Cell Disease
Conditions: Anemia, Sickle Cell
Intervention: Autologous Enriched CD34+ Cell Fraction That Contains CD34+ Cells Transduced With Lentiviral Vector Encoding Human Γ-globinG16D And Short-hairpin RNA734
Conditions: Anemia, Sickle Cell
Intervention: Autologous Enriched CD34+ Cell Fraction That Contains CD34+ Cells Transduced With Lentiviral Vector Encoding Human Γ-globinG16D And Short-hairpin RNA734
October 3, 2019
975
NCT00598273
Completed
Completed
Safety & Efficacy of Peginesatide for the Treatment of Anemia in Participants With Chronic Renal Failure Not on Dialysis
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Peginesatide, Darbepoetin Alfa
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Peginesatide, Darbepoetin Alfa
February 6, 2013
976
NCT00598442
Completed
Completed
Safety and Efficacy of Peginesatide for the Treatment of Anemia in Participants With Chronic Renal Failure Not on Dialysis
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Peginesatide, Darbepoetin Alfa
Conditions: Chronic Renal Failure; Chronic Kidney Disease; Anemia
Intervention: Peginesatide, Peginesatide, Darbepoetin Alfa
February 6, 2013
977
NCT04011345
Recruiting
Recruiting
Folic Acid Supplementation in Children With Sickle Cell Disease
Conditions: Anemia, Sickle Cell
Intervention: Folic Acid Supplement, Placebo
Conditions: Anemia, Sickle Cell
Intervention: Folic Acid Supplement, Placebo
January 7, 2020
978
NCT00270101
Completed
Completed
The Effect of Epoetin Alfa on the Anemia of Patients With Multiple Myeloma
Conditions: Anemia; Multiple Myeloma
Intervention: Epoetin Alfa
Conditions: Anemia; Multiple Myeloma
Intervention: Epoetin Alfa
May 17, 2011
979
NCT00017654
Unknown status
Unknown status
Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia
Conditions: Graft Versus Host Disease; Aplastic Anemia
Intervention: Anti-thymocyte Globulin, Cyclophosphamide, Cyclosporine, Methylprednisolone, Allogeneic Bone Marrow Transplantation
Conditions: Graft Versus Host Disease; Aplastic Anemia
Intervention: Anti-thymocyte Globulin, Cyclophosphamide, Cyclosporine, Methylprednisolone, Allogeneic Bone Marrow Transplantation
June 23, 2005
980
NCT02962648
Completed
Completed
An Extension Trial to Assess the Safety of Re-dosing of Iron Isomaltoside (Monofer®)
Conditions: Iron-Deficiency Anemia
Intervention: Iron Isomaltoside
Conditions: Iron-Deficiency Anemia
Intervention: Iron Isomaltoside
May 22, 2019
981
NCT03241381
Completed
Completed
Prevalence of Serum-Vitamin D Abnormalities, Periodontitis and Anaemia in Patients With Melasma
Conditions: Melasma, Periodontitis, Vitamin D Abnormalities, Anaemia
Intervention: Vitamin D Serum Assay Study And Control Groups, Photometry, Russels Periodontal Index
Conditions: Melasma, Periodontitis, Vitamin D Abnormalities, Anaemia
Intervention: Vitamin D Serum Assay Study And Control Groups, Photometry, Russels Periodontal Index
December 18, 2017
982
NCT03374111
Recruiting
Recruiting
Colla Corii Asini Treating Anemia in Pregnant Women With Thalassemia(Presenting the Syndrome of Blood Deficiency)
Conditions: Thalassemia
Intervention: Colla Corii Asini, A Simulate Agent Of Colla Corii Asini Granule
Conditions: Thalassemia
Intervention: Colla Corii Asini, A Simulate Agent Of Colla Corii Asini Granule
December 26, 2018
983
NCT01018576
Terminated
Terminated
Delayed Cord Clamping in Premature Infants
Conditions: Hypothermia; Anemia
Intervention: Delayed Cord Clamping
Conditions: Hypothermia; Anemia
Intervention: Delayed Cord Clamping
December 1, 2014
984
NCT02143830
Recruiting
Recruiting
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
Conditions: Fanconi Anemia; Severe Marrow Failure; Myelodysplastic Syndrome (MDS); Acute Myelogenous Leukemia (AML)
Intervention: Busulfan, Cyclophosphamide, Fludarabine, Rabbit ATG, G-CSF, Peripheral Blood Stem Cell
Conditions: Fanconi Anemia; Severe Marrow Failure; Myelodysplastic Syndrome (MDS); Acute Myelogenous Leukemia (AML)
Intervention: Busulfan, Cyclophosphamide, Fludarabine, Rabbit ATG, G-CSF, Peripheral Blood Stem Cell
July 9, 2019
985
NCT03988712
Completed
Completed
Measures to Increase the Effectiveness of Fast Track Colorectal Clinics for Iron Deficiency Anaemia.
Conditions: Colorectal Cancer
Intervention: Colonoscopy, Gastroscopy, Virtual Colonoscopy, CT Scan
Conditions: Colorectal Cancer
Intervention: Colonoscopy, Gastroscopy, Virtual Colonoscopy, CT Scan
June 18, 2019
986
NCT02815449
Completed
Completed
Assessment of the Bioavailability of Iron in Iron Fortified Bouillon Cubes in Healthy Nigerian Women
Conditions: Iron Deficiency Anemia
Intervention: Meals Prepared With Iron Fortified Cube With Low Stabilizer Level, Meals Prepared With Iron Fortified Cube With Medium Stabilizer Level, Meals Prepared With Iron Fortified Cube With High Stabilizer Level
Conditions: Iron Deficiency Anemia
Intervention: Meals Prepared With Iron Fortified Cube With Low Stabilizer Level, Meals Prepared With Iron Fortified Cube With Medium Stabilizer Level, Meals Prepared With Iron Fortified Cube With High Stabilizer Level
July 31, 2017
987
NCT03397017
Enrolling by invitation
Enrolling by invitation
Transfusion Treatment in Patients With SCD
Conditions: Anemia, Sickle Cell
Intervention: Transfusion
Conditions: Anemia, Sickle Cell
Intervention: Transfusion
April 3, 2019
988
NCT03380351
Recruiting
Recruiting
Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)
Conditions: Anemia, Sickle Cell
Intervention: SCDIC Interventions, SCDIC Control Groups
Conditions: Anemia, Sickle Cell
Intervention: SCDIC Interventions, SCDIC Control Groups
September 3, 2019
989
NCT03716726
Not yet recruiting
Not yet recruiting
Sickle Cell Anemia WE CARE
Conditions: Sickle Cell Disease
Intervention: WE CARE SDoH Screening Survey, Family Resource Book, Standard Of Care
Conditions: Sickle Cell Disease
Intervention: WE CARE SDoH Screening Survey, Family Resource Book, Standard Of Care
November 27, 2019
990
NCT00874172
Completed
Completed
Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy
Conditions: Sickle Cell Anemia
Intervention: Rapid Optimized Analgesic Strategy, Current Analgesic Strategy
Conditions: Sickle Cell Anemia
Intervention: Rapid Optimized Analgesic Strategy, Current Analgesic Strategy
December 17, 2012
991
NCT02620137
Completed
Completed
Maintenance of Multivitamin Supplements After Sleeve Gastrectomy
Conditions: Iron Deficiency Anemia
Intervention: Multicentrum® (Pfizer, Spain) 3 Months, Multicentrum® (Pfizer, Spain) 12 Months
Conditions: Iron Deficiency Anemia
Intervention: Multicentrum® (Pfizer, Spain) 3 Months, Multicentrum® (Pfizer, Spain) 12 Months
November 28, 2015
992
NCT02404012
Recruiting
Recruiting
Iron Supplement to Improve Iron Status Following Bariatric Surgery
Conditions: Anemia, Iron Deficiency
Intervention: Oral Iron Supplementation
Conditions: Anemia, Iron Deficiency
Intervention: Oral Iron Supplementation
April 18, 2017
993
NCT00261677
Completed
Completed
A Study to Evaluate the Effect of Weekly PROCRIT (Epoetin Alfa) or Placebo on Anemia and Quality of Life in Children With Cancer Undergoing Chemotherapy
Conditions: Anemia; Hodgkin Disease; Leukemia; Lymphoma, Non-hodgkin
Intervention: Epoetin Alfa
Conditions: Anemia; Hodgkin Disease; Leukemia; Lymphoma, Non-hodgkin
Intervention: Epoetin Alfa
May 19, 2011
994
NCT02498886
Completed
Completed
February 3, 2017
995
NCT00276146
Withdrawn
Withdrawn
Dipyridamole/Magnesium To Improve Sickle Cell Hydration
Conditions: Anemia, Sickle Cell
Intervention: Oral Dipyridamole, Oral Magnesium, Or A Combination Of Both
Conditions: Anemia, Sickle Cell
Intervention: Oral Dipyridamole, Oral Magnesium, Or A Combination Of Both
August 5, 2013
996
NCT02671175
Unknown status
Unknown status
Post-discharge Malaria Chemoprevention(PMC) Study
Conditions: Malaria; Severe Anemia
Intervention: Dihydroartemisinin-piperaquine, Dihydroartemisinin-piperaquine Placebo
Conditions: Malaria; Severe Anemia
Intervention: Dihydroartemisinin-piperaquine, Dihydroartemisinin-piperaquine Placebo
October 5, 2016
997
NCT01034592
Terminated
Terminated
Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia
Conditions: Anemia; Leukemia; Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes (MDS)
Intervention: Lenalidomide
Conditions: Anemia; Leukemia; Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes (MDS)
Intervention: Lenalidomide
June 27, 2017
998
NCT02310607
Completed
Completed
Non-invasive Optical Detection of Iron Deficiency
Conditions: Anemia, Iron-Deficiency
Intervention: Not An Interventional Study
Conditions: Anemia, Iron-Deficiency
Intervention: Not An Interventional Study
April 7, 2015
999
NCT03069430
Completed
Completed
A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I
Conditions: Anemia, Sickle Cell
Intervention: SELFY (Self Management For Youth With SCD)
Conditions: Anemia, Sickle Cell
Intervention: SELFY (Self Management For Youth With SCD)
May 4, 2018
1000
NCT00727571
Completed
Completed
LEARN-6™: A Prospective, Observational Nursing Home Study
Conditions: Anemia; Chronic Kidney Disease
Intervention: Observations
Conditions: Anemia; Chronic Kidney Disease
Intervention: Observations
July 18, 2014
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.