Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Anemia
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NCTID/Status
Study
Last Changed
2701
NCT01895998
Completed
Completed
Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Albuterol
Conditions: Sickle Cell Disease
Intervention: Albuterol
December 2, 2014
2702
NCT00801931
Terminated
Terminated
Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders
Conditions: Leukemia; Lymphoma; Neuroblastoma; Immunodeficiencies; Anemia
Intervention: Alemtuzumab, Total Body Irradiation, Melphalan, Busulfan, Phenytoin, Fludarabine, Cyclophosphamide, Horse Antithymocyte Globulin, Rabbit Antithymocyte Globulin, Thiotepa
Conditions: Leukemia; Lymphoma; Neuroblastoma; Immunodeficiencies; Anemia
Intervention: Alemtuzumab, Total Body Irradiation, Melphalan, Busulfan, Phenytoin, Fludarabine, Cyclophosphamide, Horse Antithymocyte Globulin, Rabbit Antithymocyte Globulin, Thiotepa
March 4, 2019
2703
NCT01141621
Terminated
Terminated
The Dallas Hereditary Spherocytosis Cohort Study
Conditions: Hereditary Spherocytosis
Conditions: Hereditary Spherocytosis
May 13, 2013
2704
NCT00367380
Completed
Completed
Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers
Conditions: MALARIA; FEVER; Sweating Fever; Chills; ANEMIA
Intervention: 413ABM, 414WRR, 418JAL
Conditions: MALARIA; FEVER; Sweating Fever; Chills; ANEMIA
Intervention: 413ABM, 414WRR, 418JAL
May 2, 2014
2705
NCT00472433
Terminated
Terminated
The Efficacy and Safety of Alemtuzumab in Auotoimmune Cytopenias
Conditions: Autoimmune Cytopenias
Intervention: Alemtuzumab
Conditions: Autoimmune Cytopenias
Intervention: Alemtuzumab
June 18, 2009
2706
NCT00367588
Completed
Completed
Low Bacterial Diet in Patients With Cytopenia
Conditions: Cytopenia
Intervention: Low Bacterial Diet
Conditions: Cytopenia
Intervention: Low Bacterial Diet
October 24, 2016
2707
NCT00774527
Completed
Completed
Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT
Conditions: Bone Marrow Failure Syndromes
Intervention: Cyclophosphamide-fludarabine-anti Thymocyte Globulin
Conditions: Bone Marrow Failure Syndromes
Intervention: Cyclophosphamide-fludarabine-anti Thymocyte Globulin
February 16, 2011
2708
NCT00367523
Completed
Completed
Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria
Conditions: Secondary Pulmonary Arterial Hypertension; Sickle Cell Disease; Pulmonary Hypertension
Conditions: Secondary Pulmonary Arterial Hypertension; Sickle Cell Disease; Pulmonary Hypertension
November 27, 2019
2709
NCT00002258
Completed
Completed
A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia
Conditions: HIV Infections; Cytopenias
Intervention: Interleukin-3
Conditions: HIV Infections; Cytopenias
Intervention: Interleukin-3
June 23, 2005
2710
NCT01617044
Completed
Completed
Probiotics in the Treatment of Iron Deficiency in Children With Restless Leg Syndrome
Conditions: Iron Deficiency; Restless Leg Syndrome
Intervention: Probiotics, Placebo
Conditions: Iron Deficiency; Restless Leg Syndrome
Intervention: Probiotics, Placebo
January 19, 2016
2711
NCT02986698
Recruiting
Recruiting
In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)
Conditions: Alpha Thalassemia Major; Hemoglobinopathy; With Thalassemia; Hemoglobinopathies; Fetal Anemia; Fetal Hydrops; Alpha; Thalassemia; Thalassemia Major; Thalassemia Alpha; A-Thalassemia
Intervention: In Utero Hematopoietic Stem Cell Transplantation
Conditions: Alpha Thalassemia Major; Hemoglobinopathy; With Thalassemia; Hemoglobinopathies; Fetal Anemia; Fetal Hydrops; Alpha; Thalassemia; Thalassemia Major; Thalassemia Alpha; A-Thalassemia
Intervention: In Utero Hematopoietic Stem Cell Transplantation
December 6, 2019
2712
NCT01507792
Completed
Completed
Iron Repletion in Chronic Cough and Iron Deficiency
Conditions: Cough; Laryngeal Disease; Bronchial Disease; Iron Deficiency
Intervention: Iron Sulphate, AntiH1-histamine, Proton Pump Inhibitor
Conditions: Cough; Laryngeal Disease; Bronchial Disease; Iron Deficiency
Intervention: Iron Sulphate, AntiH1-histamine, Proton Pump Inhibitor
January 8, 2012
2713
NCT00041574
Terminated
Terminated
Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide
Conditions: Pulmonary Hypertension; Lung Disease; Sickle Cell Disease; Cardiac Transplant; Lung Transplant
Intervention: Inhaled Nitric Oxide
Conditions: Pulmonary Hypertension; Lung Disease; Sickle Cell Disease; Cardiac Transplant; Lung Transplant
Intervention: Inhaled Nitric Oxide
September 8, 2016
2714
NCT02392910
Completed
Completed
Hospitalization & Mortality in Patients With Iron Deficiency CKD and HF Treated With i.v. Iron.
Conditions: Iron Deficiency; Heart Failure; Chronic Kidney Disease
Intervention: Iron Sucrose, Placebo
Conditions: Iron Deficiency; Heart Failure; Chronic Kidney Disease
Intervention: Iron Sucrose, Placebo
March 18, 2015
2715
NCT00003398
Completed
Completed
Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
Conditions: Anemia; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
Intervention: Anti-thymocyte Globulin, Filgrastim, Cyclophosphamide, Thiotepa, Allogeneic Bone Marrow Transplantation, Bone Marrow Ablation With Stem Cell Support, Radiation Therapy
Conditions: Anemia; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
Intervention: Anti-thymocyte Globulin, Filgrastim, Cyclophosphamide, Thiotepa, Allogeneic Bone Marrow Transplantation, Bone Marrow Ablation With Stem Cell Support, Radiation Therapy
October 15, 2019
2716
NCT00000595
Completed
Completed
Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis
Conditions: Anemia (Iron-Loading); Beta-Thalassemia; Hematologic Diseases; Hemoglobinopathies; Thalassemia; Iron Overload; Hemochromatosis
Intervention: Deferoxamine
Conditions: Anemia (Iron-Loading); Beta-Thalassemia; Hematologic Diseases; Hemoglobinopathies; Thalassemia; Iron Overload; Hemochromatosis
Intervention: Deferoxamine
November 25, 2013
2717
NCT02761564
Completed
Completed
SvO2 Trigger in Transfusion Strategy After Cardiac Surgery
Conditions: Undergoing Nonemergent Cardiac Surgery; Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure); Anemia (<9g/dL) Requiring Blood Transfusion; Hemodynamic and Respiratory Stability; Bleeding Graded as Insignificant, Mild, Moderate of Universal Definition of Perioperative Bleeding
Intervention: Red Blood Cell Tranfusion, ScvO2 Measure
Conditions: Undergoing Nonemergent Cardiac Surgery; Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure); Anemia (<9g/dL) Requiring Blood Transfusion; Hemodynamic and Respiratory Stability; Bleeding Graded as Insignificant, Mild, Moderate of Universal Definition of Perioperative Bleeding
Intervention: Red Blood Cell Tranfusion, ScvO2 Measure
March 20, 2019
2718
NCT03798028
Recruiting
Recruiting
The Safety and Effects of Mesenchymal Stem Cell (MSCs) in the Treatment of Rheumatoid Arthritis
Conditions: Rheumatoid Arthritis
Intervention: UC-MSCs
Conditions: Rheumatoid Arthritis
Intervention: UC-MSCs
January 7, 2019
2719
NCT01563367
Completed
Completed
A Prospective, Comparative Study of Intravenous Iron Isomaltoside 1000 (Monofer®) Administered by Infusions to Non-Anaemic Patients Undergoing Elective or Sub-Acute Coronary Artery Bypass Graft, Valve Replacement or a Combination Thereof
Conditions: Non-anaemic Patients Undergoing Cardiac Surgery
Intervention: Iron Isomaltoside 1000 (Monofer®), Natriumklorid 9 Mg/ml, Fresenius Kabi
Conditions: Non-anaemic Patients Undergoing Cardiac Surgery
Intervention: Iron Isomaltoside 1000 (Monofer®), Natriumklorid 9 Mg/ml, Fresenius Kabi
April 28, 2014
2720
NCT00111098
Completed
Completed
Treatment for Subjects With Chronic Kidney Disease (CKD) Not Receiving Dialysis
Conditions: Kidney Disease
Intervention: Darbepoetin Alfa
Conditions: Kidney Disease
Intervention: Darbepoetin Alfa
August 7, 2008
2721
NCT01511848
Unknown status
Unknown status
Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload
Conditions: Beta-thalassemia Major; Sickle Cell Disease; Iron Hemosiderosis
Intervention: DFP (ferriprox) And Deferasirox (ICL 670), DFP, DFO
Conditions: Beta-thalassemia Major; Sickle Cell Disease; Iron Hemosiderosis
Intervention: DFP (ferriprox) And Deferasirox (ICL 670), DFP, DFO
February 3, 2012
2722
NCT01911871
Completed
Completed
Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations
Conditions: Thalassemia; Sickle Cell Disease; Myelodysplasia
Intervention: Blood Sample
Conditions: Thalassemia; Sickle Cell Disease; Myelodysplasia
Intervention: Blood Sample
April 9, 2015
2723
NCT00443339
Unknown status
Unknown status
Darbepoetin Alpha in Myelodysplastic Syndromes (MDS)
Conditions: Myelodysplastic Syndromes
Intervention: Darbepoetin
Conditions: Myelodysplastic Syndromes
Intervention: Darbepoetin
May 15, 2007
2724
NCT00436995
Completed
Completed
Extension From Weekly to Once Every Other Week Darbepoetin Alfa Administration in Subjects With Chronic Kidney Disease Receiving Dialysis
Conditions: Chronic Kidney Disease
Intervention: Darbepoetin Alfa
Conditions: Chronic Kidney Disease
Intervention: Darbepoetin Alfa
January 20, 2011
2725
NCT03105271
Recruiting
Recruiting
Acute Kidney Injury in Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease; Kidney Injury; Kidney Diseases; Kidney Disease, Chronic
Conditions: Sickle Cell Disease; Kidney Injury; Kidney Diseases; Kidney Disease, Chronic
November 5, 2019
2726
NCT00499187
Completed
Completed
Fanconi Syndrome Due to ARVs in HIV-Infected Persons
Conditions: HIV Infections; Fanconi Syndrome; Kidney Disease; Renal Impairment
Intervention: Blood Draws
Conditions: HIV Infections; Fanconi Syndrome; Kidney Disease; Renal Impairment
Intervention: Blood Draws
March 14, 2014
2727
NCT00301912
Withdrawn
Withdrawn
Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Conditions: Anemia; Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Intervention: Filgrastim, Busulfan, Fludarabine Phosphate, Methotrexate, Tacrolimus, Allogeneic Bone Marrow Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Peripheral Blood Stem Cell Transplantation
Conditions: Anemia; Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Intervention: Filgrastim, Busulfan, Fludarabine Phosphate, Methotrexate, Tacrolimus, Allogeneic Bone Marrow Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Peripheral Blood Stem Cell Transplantation
October 1, 2012
2728
NCT01048905
Completed
Completed
Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension
Conditions: Pulmonary Hypertension; Sickle Cell Disease; Thalassemia
Intervention: L-Glutamine, L-Glutamine
Conditions: Pulmonary Hypertension; Sickle Cell Disease; Thalassemia
Intervention: L-Glutamine, L-Glutamine
July 17, 2014
2729
NCT02648126
Unknown status
Unknown status
Pure Red Cell Aplasia in Patients With Chronic Kidney Disease and in Use of Epoetin Alfa
Conditions: Red-Cell Aplasia, Pure; Renal Insufficiency, Chronic
Intervention: Pure Red Cell Aplasia Diagnostic Confirmation
Conditions: Red-Cell Aplasia, Pure; Renal Insufficiency, Chronic
Intervention: Pure Red Cell Aplasia Diagnostic Confirmation
January 5, 2016
2730
NCT03128996
Recruiting
Recruiting
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
Conditions: Severe Sickle Cell Disease; Bone Marrow Failure Syndromes; Metabolic Disorders; Immunologic Disorders; Hemoglobinopathies; Non-malignant Disorders
Intervention: RIC Regimen, GVHD Prophylaxis Regimen
Conditions: Severe Sickle Cell Disease; Bone Marrow Failure Syndromes; Metabolic Disorders; Immunologic Disorders; Hemoglobinopathies; Non-malignant Disorders
Intervention: RIC Regimen, GVHD Prophylaxis Regimen
October 1, 2019
2731
NCT03457571
Completed
Completed
Clinical Observational Study: IBD Patients With Restless-legs-syndrome and Iron Deficiency Syndrome
Conditions: Inflammatory Bowel Diseases; Restless Legs Syndrome; Iron-deficiency
Conditions: Inflammatory Bowel Diseases; Restless Legs Syndrome; Iron-deficiency
March 6, 2018
2732
NCT03329365
Recruiting
Recruiting
Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS
Conditions: Paroxysmal Nocturnal Hemoglobinuria; Embolic Stroke of Undetermined Source; Transient Ischemic Attack; Cerebral Vein Thrombosis
Conditions: Paroxysmal Nocturnal Hemoglobinuria; Embolic Stroke of Undetermined Source; Transient Ischemic Attack; Cerebral Vein Thrombosis
February 12, 2019
2733
NCT00211068
Completed
Completed
A Study of Risk Factors for Anti-erythropoietin Antibody Positive Pure Red Cell Aplasia Among Patients With Chronic Kidney Disease Receiving Epoetin Alfa
Conditions: Pure Red-cell Aplasia
Intervention: No Intervention
Conditions: Pure Red-cell Aplasia
Intervention: No Intervention
April 29, 2013
2734
NCT01519830
Completed
Completed
Iron Substitution in Blood Donors
Conditions: Fatigue
Intervention: Iron Carboxymaltose (Ferinject), Placebo
Conditions: Fatigue
Intervention: Iron Carboxymaltose (Ferinject), Placebo
February 27, 2013
2735
NCT02146053
Completed
Completed
Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron.
Conditions: Anemia; Constipation; Diarrhea; Abdominal Pain; Heartburn; Side Effect
Intervention: Ferrous Sulfate, Placebo
Conditions: Anemia; Constipation; Diarrhea; Abdominal Pain; Heartburn; Side Effect
Intervention: Ferrous Sulfate, Placebo
February 3, 2017
2736
NCT02459223
Completed
Completed
Study of Blood Parameters of the Malnourished Children: Before and After Giving Nutritional Biscuit's Treatment
Conditions: Undernutrition
Intervention: Nutritional Biscuits And Khichadi, Khichadi
Conditions: Undernutrition
Intervention: Nutritional Biscuits And Khichadi, Khichadi
May 31, 2015
2737
NCT04148859
Recruiting
Recruiting
Feto-Fetal Transfusion Syndrome in Multiple Pregnancies
Conditions: Pregnant With Complication
Intervention: Amnioreduction
Conditions: Pregnant With Complication
Intervention: Amnioreduction
October 30, 2019
2738
NCT02566577
Terminated
Terminated
Physiologic Effects of RBC Transfusion
Conditions: Red Blood Cell Transfusion
Intervention: Fresh Red Blood Cell (RBC) Transfusion, Storage-aged Red Blood Cell (RBC) Transfusion, Electronic Infusion Pump
Conditions: Red Blood Cell Transfusion
Intervention: Fresh Red Blood Cell (RBC) Transfusion, Storage-aged Red Blood Cell (RBC) Transfusion, Electronic Infusion Pump
May 3, 2019
2739
NCT00735930
Completed
Completed
Lenalidomide and Alvocidib in Treating Patients With Relapsed or Refractory B-cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Conditions: Anemia; Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Thrombocytopenia
Intervention: Alvocidib Hydrochloride, Lenalidomide, Pharmacological Study, Laboratory Biomarker Analysis
Conditions: Anemia; Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Thrombocytopenia
Intervention: Alvocidib Hydrochloride, Lenalidomide, Pharmacological Study, Laboratory Biomarker Analysis
April 1, 2015
2740
NCT03171909
Recruiting
Recruiting
Austrian Registry on the Outcome of Monochorionic Pregnancies
Conditions: Twin Dichorionic Diamniotic Placenta; Twin Monochorionic Monoamniotic Placenta; Twin-To-Twin Transfusion Syndrome; Twin Pregnancy With Antenatal Problem
Conditions: Twin Dichorionic Diamniotic Placenta; Twin Monochorionic Monoamniotic Placenta; Twin-To-Twin Transfusion Syndrome; Twin Pregnancy With Antenatal Problem
May 28, 2017
2741
NCT01745120
Completed
Completed
A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants
Conditions: β-thalassemia Major
Intervention: LentiGlobin BB305 Drug Product
Conditions: β-thalassemia Major
Intervention: LentiGlobin BB305 Drug Product
April 16, 2019
2742
NCT01392989
Completed
Completed
Post T-plant Infusion of Allogeneic Cytokine Induced Killer (CIK) Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative Disorders
Conditions: Neural Tube Defects; Anemia; Leukemia, Myeloid; Bone Marrow Transplant Failure; Myelodysplastic Syndromes (MDS); Myeloproliferative Disorders
Intervention: CIK Cells, Cyclosporine, Mycophenolate Mofetil, Thymoglobulin, Total Lymphoid Irradiation (TLI)
Conditions: Neural Tube Defects; Anemia; Leukemia, Myeloid; Bone Marrow Transplant Failure; Myelodysplastic Syndromes (MDS); Myeloproliferative Disorders
Intervention: CIK Cells, Cyclosporine, Mycophenolate Mofetil, Thymoglobulin, Total Lymphoid Irradiation (TLI)
April 18, 2019
2743
NCT02249624
Active, not recruiting
Active, not recruiting
The Utility of MRI Scoring to Predict Neurodevelopmental Outcomes in Survivors of Twin-to-Twin Transfusion Syndrome
Conditions: Fetofetal Transfusion
Conditions: Fetofetal Transfusion
December 13, 2019
2744
NCT03455257
Active, not recruiting
Active, not recruiting
Evaluation of a Cash Transfer Program in Low-Income Families in Guinea-Bissau
Conditions: Per Capita Food Consumption Expenditure; Childhood Growth; Childhood Cognition; Anemia; School Registration and Attendence; Diabetes
Intervention: Cash Transfer
Conditions: Per Capita Food Consumption Expenditure; Childhood Growth; Childhood Cognition; Anemia; School Registration and Attendence; Diabetes
Intervention: Cash Transfer
February 27, 2018
2745
NCT02996786
Completed
Completed
Effects of Danggui Buxue Tang on Blood Biochemical Parameters in Male Recreational Runners
Conditions: Sports Anemia; Inflammation; Oxidative Stress; Iron Deficiency; Hemolysis; Fatigue
Intervention: Danggui Buxue Tang, Placebo
Conditions: Sports Anemia; Inflammation; Oxidative Stress; Iron Deficiency; Hemolysis; Fatigue
Intervention: Danggui Buxue Tang, Placebo
April 18, 2018
2746
NCT00470899
Completed
Completed
Effect of Placental Drainage of Fetal Blood at Cesarean Section on the Incidence of Feto-Maternal Transfusion
Conditions: Fetomaternal Transfusion
Intervention: Drainage Of Placenta Of Fetal Blood
Conditions: Fetomaternal Transfusion
Intervention: Drainage Of Placenta Of Fetal Blood
April 6, 2015
2747
NCT03367546
Recruiting
Recruiting
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases
Conditions: Sickle Cell Disease; Thalassemia; High Risk Hematologic Disorders; Cerebral Adrenoleukodystrophy; Inherited Metabolic Disorders
Intervention: Blood And Marrow Transplant
Conditions: Sickle Cell Disease; Thalassemia; High Risk Hematologic Disorders; Cerebral Adrenoleukodystrophy; Inherited Metabolic Disorders
Intervention: Blood And Marrow Transplant
March 20, 2019
2748
NCT01049854
Completed
Completed
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant
Conditions: Leukemia; Lymphoma; Bone Marrow Failure; Immunodeficiencies; Histiocytosis; Sickle Cell Disease; Beta Thalassemia; Inborn Errors of Metabolism
Intervention: Full Intensity With TBI, Full Intensity, Reduced Intensity, Reduced Intensity (Fanconi)
Conditions: Leukemia; Lymphoma; Bone Marrow Failure; Immunodeficiencies; Histiocytosis; Sickle Cell Disease; Beta Thalassemia; Inborn Errors of Metabolism
Intervention: Full Intensity With TBI, Full Intensity, Reduced Intensity, Reduced Intensity (Fanconi)
August 20, 2018
2749
NCT03938324
Enrolling by invitation
Enrolling by invitation
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
Conditions: Sickle Cell Disease; Chronic Kidney Diseases; Systemic Lupus Erythematosus; Childhood Cancer; Inflammatory Bowel Diseases; Asthma; Stem Cell Transplant; Organ Transplant; Diabetes Mellitus, Type 1
Intervention: PiCASO Intervention Group, Sham Comparator: Attention Control Group
Conditions: Sickle Cell Disease; Chronic Kidney Diseases; Systemic Lupus Erythematosus; Childhood Cancer; Inflammatory Bowel Diseases; Asthma; Stem Cell Transplant; Organ Transplant; Diabetes Mellitus, Type 1
Intervention: PiCASO Intervention Group, Sham Comparator: Attention Control Group
January 14, 2020
2750
NCT00682799
Completed
Completed
Serial Analysis of Chimerism in Patients With Refractory Cytopenia (RC) Transplanted With Reduced Intensity Conditioning (RIC)
Conditions: Refractory Cytopenia of Childhood; Reduced Intensity Conditioning (RIC); Myelodysplastic Syndrome (MDS); Hematopoietic Stem Cell Transplantation (SCT)
Conditions: Refractory Cytopenia of Childhood; Reduced Intensity Conditioning (RIC); Myelodysplastic Syndrome (MDS); Hematopoietic Stem Cell Transplantation (SCT)
January 14, 2015
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.