Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Dementia
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NCTID/Status
Study
Last Changed
601
NCT03177772
Recruiting
Recruiting
Group Therapy For Dementia Caregivers At Risk For Complicated Grief
Conditions: Grief
Intervention: Pre-loss Group Therapy
Conditions: Grief
Intervention: Pre-loss Group Therapy
April 15, 2019
602
NCT03014570
Active, not recruiting
Active, not recruiting
Testing the Implementation of EIT-4-BPSD
Conditions: Dementia; Behavioral and Psychological Symptoms of Dementia (BPSD)
Intervention: EIT-4-BPSD, Education-only Control
Conditions: Dementia; Behavioral and Psychological Symptoms of Dementia (BPSD)
Intervention: EIT-4-BPSD, Education-only Control
October 31, 2019
603
NCT00889603
Completed
Completed
Non-Interventional Study With Aricept® Evess
Conditions: Alzheimer's Disease; Vascular Dementia
Intervention: Aricept® Evess
Conditions: Alzheimer's Disease; Vascular Dementia
Intervention: Aricept® Evess
March 4, 2011
604
NCT00249145
Completed
Completed
A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia
Conditions: Dementia; Alzheimer Disease; Dementia, Vascular
Intervention: Risperidone
Conditions: Dementia; Alzheimer Disease; Dementia, Vascular
Intervention: Risperidone
January 13, 2011
605
NCT03748303
Not yet recruiting
Not yet recruiting
Allopregnanolone Regenerative Therapeutic for Early Alzheimer's Disease: Intramuscular Study
Conditions: Alzheimer Dementia
Intervention: Allopregnanolone
Conditions: Alzheimer Dementia
Intervention: Allopregnanolone
September 25, 2019
606
NCT03325608
Recruiting
Recruiting
Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients
Conditions: Dementia
Intervention: POISED Care, Usual Care
Conditions: Dementia
Intervention: POISED Care, Usual Care
April 30, 2019
607
NCT03958994
Recruiting
Recruiting
A Systems Approach to Falls and Discharge Planning
Conditions: Dementia; Falls; Discharge Planning
Intervention: Qualitative Interviews
Conditions: Dementia; Falls; Discharge Planning
Intervention: Qualitative Interviews
November 6, 2019
608
NCT02415062
Unknown status
Unknown status
The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With Dementia
Conditions: Parkinson's Disease
Intervention: Donepezil
Conditions: Parkinson's Disease
Intervention: Donepezil
August 5, 2015
609
NCT01435551
No longer available
No longer available
Using Hypnotherapy For Dementia & Alzheimer's
Conditions: Alzheimer Disease
Intervention: Hypnotherapy
Conditions: Alzheimer Disease
Intervention: Hypnotherapy
February 2, 2016
610
NCT03341091
Completed
Completed
Effects of Tai-chi Programme on Mobility of People With Dementia
Conditions: Accidental Falls
Intervention: Tai-chi Group
Conditions: Accidental Falls
Intervention: Tai-chi Group
November 9, 2017
611
NCT00988117
Completed
Completed
The Effects of the Rivastigmine Patch on Parkinson's Disease With Memory and/or Thinking Problems
Conditions: Parkinsons Disease With Dementia; Parkinsons Disease With Mild to Moderate Memory and/or Thinking Problems
Intervention: Rivastigmine Patch 9.5 Cm2
Conditions: Parkinsons Disease With Dementia; Parkinsons Disease With Mild to Moderate Memory and/or Thinking Problems
Intervention: Rivastigmine Patch 9.5 Cm2
January 24, 2014
612
NCT01147679
Unknown status
Unknown status
Study of Social Behavior and Emotion in Frontotemporal Dementia, Alzheimer's Disease and Controls
Conditions: Frontotemporal Dementia; Frontotemporal Degeneration; Alzheimer's Disease; Social Behavior
Conditions: Frontotemporal Dementia; Frontotemporal Degeneration; Alzheimer's Disease; Social Behavior
October 27, 2011
613
NCT03643003
Completed
Completed
Music Therapy for Persons With Dementia
Conditions: Quality of Life; Social Interaction; Emotions; Mood; Feelings; Alzheimer Disease; Dementia
Intervention: Music Therapy, Non-Music Verbal Interaction (Placebo)
Conditions: Quality of Life; Social Interaction; Emotions; Mood; Feelings; Alzheimer Disease; Dementia
Intervention: Music Therapy, Non-Music Verbal Interaction (Placebo)
October 4, 2018
614
NCT00685009
Completed
Completed
The Women's Health Initiative Memory Study (The WHIMS Study)
Conditions: Dementia Syndromes
Intervention: Estrogen Hormone Therapy, Estrogen Plus Progesterone Hormone Therapy, Placebo
Conditions: Dementia Syndromes
Intervention: Estrogen Hormone Therapy, Estrogen Plus Progesterone Hormone Therapy, Placebo
October 16, 2015
615
NCT02871427
Terminated
Terminated
Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder
Conditions: Lewy Body Dementia; Dementia With Lewy Bodies; Parkinson's Disease Dementia; Visual Hallucinations; REM Sleep Behavior Disorder
Intervention: Nelotanserin
Conditions: Lewy Body Dementia; Dementia With Lewy Bodies; Parkinson's Disease Dementia; Visual Hallucinations; REM Sleep Behavior Disorder
Intervention: Nelotanserin
March 26, 2019
616
NCT01599975
Unknown status
Unknown status
A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV
Conditions: HIV Dementia
Intervention: Long Acting Methylphenidate, Long Acting Methylphenidate, Matched Placebo
Conditions: HIV Dementia
Intervention: Long Acting Methylphenidate, Long Acting Methylphenidate, Matched Placebo
May 14, 2012
617
NCT00002044
Completed
Completed
A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases
Conditions: AIDS Dementia Complex; Neuromuscular Diseases; HIV Infections
Intervention: Zidovudine
Conditions: AIDS Dementia Complex; Neuromuscular Diseases; HIV Infections
Intervention: Zidovudine
June 23, 2005
618
NCT03587012
Enrolling by invitation
Enrolling by invitation
Brain Fitness APP for Cognitive Enhancement
Conditions: Mild Cognitive Impairment; Alzheimer Dementia
Intervention: Brain Fitness App, Brain Fitness App With TACS
Conditions: Mild Cognitive Impairment; Alzheimer Dementia
Intervention: Brain Fitness App, Brain Fitness App With TACS
February 4, 2019
619
NCT02855021
Unknown status
Unknown status
Prediction of Dementia in Parkinson's Disease by Measuring Cerebral Metabolism With PET Scan
Conditions: Parkinson Disease
Intervention: Explorations
Conditions: Parkinson Disease
Intervention: Explorations
July 31, 2016
620
NCT01126775
Unknown status
Unknown status
Neuro-Prävention im Rahmen Des Interventionsprojektes INVADE-2 (Follow-up Studie)
Conditions: Stroke; Dementia
Conditions: Stroke; Dementia
January 22, 2013
621
NCT03907748
Not yet recruiting
Not yet recruiting
Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia
Conditions: Dementia; Dementia, Vascular; Dementia With Lewy Bodies; Dementia, Mixed; Dementia Alzheimers; Behavioural and Psychiatric Symptoms of Dementia; Depression; Quality of Life
Intervention: Music Intervention, Reading Intervention
Conditions: Dementia; Dementia, Vascular; Dementia With Lewy Bodies; Dementia, Mixed; Dementia Alzheimers; Behavioural and Psychiatric Symptoms of Dementia; Depression; Quality of Life
Intervention: Music Intervention, Reading Intervention
September 10, 2019
622
NCT02503462
Terminated
Terminated
Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals
Conditions: AIDS-related Dementia Complex
Intervention: Darunavir, Ritonavir, Cobicistat
Conditions: AIDS-related Dementia Complex
Intervention: Darunavir, Ritonavir, Cobicistat
February 1, 2017
623
NCT01965392
Completed
Completed
Efficiency of an Educational Program for Informal Caregivers of Hospitalized, Dependent Patients: Cluster Randomised Trial
Conditions: Dependence, Dementias
Conditions: Dependence, Dementias
October 15, 2013
624
NCT03622814
Active, not recruiting
Active, not recruiting
Partners at Meals - Respite Care and Home (PAM)
Conditions: Dementia, Alzheimer Type; Weight Loss
Intervention: Partners At Meals, Enhanced Usual Condition
Conditions: Dementia, Alzheimer Type; Weight Loss
Intervention: Partners At Meals, Enhanced Usual Condition
July 31, 2019
625
NCT03234686
Recruiting
Recruiting
Deferiprone to Delay Dementia (The 3D Study)
Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease; Mild Alzheimer's Disease
Intervention: Deferiprone 600mg Delayed Release Tablets, Placebo Oral Tablet
Conditions: Mild Cognitive Impairment; Prodromal Alzheimer's Disease; Mild Alzheimer's Disease
Intervention: Deferiprone 600mg Delayed Release Tablets, Placebo Oral Tablet
January 22, 2018
626
NCT01665846
Completed
Completed
Ferumoxytol-enhanced Brain MRI in HIV-associated Neurocognitive Disorders
Conditions: HIV Dementia
Intervention: Ferumoxytol
Conditions: HIV Dementia
Intervention: Ferumoxytol
May 30, 2018
627
NCT02103673
Completed
Completed
DAOIB for the Treatment of Cognitive Function and Behavioral and Psychological Symptoms of Dementia
Conditions: Behavioral and Psychological Symptoms in Alzheimer's Disease; Behavioral and Psychological Symptoms in Vascular Dementia
Intervention: DAOIB, Placebo
Conditions: Behavioral and Psychological Symptoms in Alzheimer's Disease; Behavioral and Psychological Symptoms in Vascular Dementia
Intervention: DAOIB, Placebo
January 23, 2018
628
NCT04123171
Recruiting
Recruiting
Cerebrovascular Correlates of Dementia in Rural Communities - The Three Villages Study
Conditions: Dementia; Cardiovascular Risk Factor; Atherosclerosis; Cerebral Small Vessel Diseases; Cognitive Decline
Intervention: Neuroimaging Studies
Conditions: Dementia; Cardiovascular Risk Factor; Atherosclerosis; Cerebral Small Vessel Diseases; Cognitive Decline
Intervention: Neuroimaging Studies
October 9, 2019
629
NCT04026919
Recruiting
Recruiting
Online Support Program for Dementia Caregivers
Conditions: Effect Increased
Intervention: OK EN CASA-ZAINDOO
Conditions: Effect Increased
Intervention: OK EN CASA-ZAINDOO
July 18, 2019
630
NCT00814502
Completed
Completed
Zolpidem CR and Hospitalized Patients With Dementia
Conditions: Dementia; Alzheimer Disease; Dementia, Vascular; Sleep Disorders; Circadian Dysregulation
Intervention: Zolpidem CR, Placebo
Conditions: Dementia; Alzheimer Disease; Dementia, Vascular; Sleep Disorders; Circadian Dysregulation
Intervention: Zolpidem CR, Placebo
April 12, 2017
631
NCT00449384
Completed
Completed
SIB-Norwegian Version, Validation and Reliability Study
Conditions: Dementia; Diagnostic Tests, Routine
Intervention: Diagnostic Screening
Conditions: Dementia; Diagnostic Tests, Routine
Intervention: Diagnostic Screening
July 2, 2007
632
NCT03721705
Recruiting
Recruiting
Renew NCP-5 for the Treatment of Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild Dementia of the Alzheimer's Type
Conditions: Alzheimer Disease; Cognitive Dysfunction; Mild Cognitive Impairment; Mild Dementia; Cognitive Decline; Dementia, Alzheimer Type
Intervention: Renew NCP-5
Conditions: Alzheimer Disease; Cognitive Dysfunction; Mild Cognitive Impairment; Mild Dementia; Cognitive Decline; Dementia, Alzheimer Type
Intervention: Renew NCP-5
October 30, 2019
633
NCT03092050
Recruiting
Recruiting
Group Therapy for Depressed Dementia Caregivers
Conditions: Depression
Intervention: Guided Imagery And Mindfulness, Facilitated Discussion
Conditions: Depression
Intervention: Guided Imagery And Mindfulness, Facilitated Discussion
March 5, 2019
634
NCT02391766
Unknown status
Unknown status
Group Intervention Empowerment Dementia
Conditions: Empowerment; Self Efficacy; Quality of Life
Intervention: Empowerment, Usual Care
Conditions: Empowerment; Self Efficacy; Quality of Life
Intervention: Empowerment, Usual Care
March 17, 2015
635
NCT03689179
Not yet recruiting
Not yet recruiting
Virtual Coaching to Maximize Dementia Caregivers' Respite Time Use
Conditions: Anxiety; Burden, Dependency; Caregiver
Intervention: Time For Living And Caring (TLC)
Conditions: Anxiety; Burden, Dependency; Caregiver
Intervention: Time For Living And Caring (TLC)
April 15, 2019
636
NCT02763683
Recruiting
Recruiting
April 24, 2019
637
NCT04108000
Recruiting
Recruiting
SPIRIT for Persons With Dementia and Complex Multimorbidity
Conditions: End Stage Renal Disease
Intervention: SPIRIT-Dementia, Usual Care
Conditions: End Stage Renal Disease
Intervention: SPIRIT-Dementia, Usual Care
November 28, 2019
638
NCT03864536
Not yet recruiting
Not yet recruiting
A Multidomain Approach to Preventing Dementia in African Americans: Cognitive Prescriptions
Conditions: Cognitive Change; Health Behavior; Health Literacy
Intervention: Cognitive Prescriptions
Conditions: Cognitive Change; Health Behavior; Health Literacy
Intervention: Cognitive Prescriptions
September 24, 2019
639
NCT02569398
Completed
Completed
An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia
Conditions: Asymptomatic Amyloid-positive
Intervention: Atabecestat, 5 Mg, Atabecestat, 25 Mg, Placebo
Conditions: Asymptomatic Amyloid-positive
Intervention: Atabecestat, 5 Mg, Atabecestat, 25 Mg, Placebo
January 18, 2019
640
NCT03857308
Recruiting
Recruiting
Eudaimonia and Sleep: Effects of a Mindfulness Intervention in Caregivers of People With Dementia
Conditions: Caregivers; Burnout; Sleep
Intervention: Mindfulness Training, Reappraisal Training
Conditions: Caregivers; Burnout; Sleep
Intervention: Mindfulness Training, Reappraisal Training
November 14, 2019
641
NCT02463734
Unknown status
Unknown status
The Dementia Quality of Life Scale for Older Family Carers (DQoL-OC) Study
Conditions: Quality of Life
Conditions: Quality of Life
December 1, 2015
642
NCT02819700
Unknown status
Unknown status
Evaluation and Characterization of Behavioural Disorders and Dementias by the Behavioural Dysexecutive Syndrome Inventory (BDSI)
Conditions: Frontotemporal Dementia; Huntington Disease; Alzheimer Disease; Semantic Dementia; Dementia, Vascular
Intervention: Prevalence Of Behavioural Dysexecutive Syndrome
Conditions: Frontotemporal Dementia; Huntington Disease; Alzheimer Disease; Semantic Dementia; Dementia, Vascular
Intervention: Prevalence Of Behavioural Dysexecutive Syndrome
June 28, 2016
643
NCT03383289
Recruiting
Recruiting
Resident-to-Resident Elder Mistreatment Intervention for Dementia Care in Assisted Living
Conditions: Assisted Living, Resident to Resident Elder Mistreatment
Intervention: R-REM Training
Conditions: Assisted Living, Resident to Resident Elder Mistreatment
Intervention: R-REM Training
February 25, 2019
644
NCT03046121
Recruiting
Recruiting
A Family-centered Intervention for Acutely-ill Persons With Dementia
Conditions: Alzheimer Disease
Intervention: Family-centered Function-focused Care (Fam-FFC)
Conditions: Alzheimer Disease
Intervention: Family-centered Function-focused Care (Fam-FFC)
January 15, 2019
645
NCT03555292
Recruiting
Recruiting
11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes
Conditions: Parkinson Disease
Intervention: 11C-PiB
Conditions: Parkinson Disease
Intervention: 11C-PiB
May 31, 2018
646
NCT01052350
Active, not recruiting
Active, not recruiting
PET Imaging in Parkinson Disease Dementia
Conditions: Parkinson's Disease
Conditions: Parkinson's Disease
January 4, 2019
647
NCT00006176
Completed
Completed
Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion Bodies
Conditions: Familial Dementia With Neuroserpin Inclusion Bodies; Nervous System Heredodegenerative Disorder
Conditions: Familial Dementia With Neuroserpin Inclusion Bodies; Nervous System Heredodegenerative Disorder
June 30, 2017
648
NCT02829892
Completed
Completed
Using Environmental Light Therapy to Improve Sleep and Neuropsychiatric Symptoms in Dementia
Conditions: Polypathology and Autonomy Loss
Intervention: Light Therapy
Conditions: Polypathology and Autonomy Loss
Intervention: Light Therapy
July 8, 2016
649
NCT03001557
Active, not recruiting
Active, not recruiting
Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia
Conditions: Irregular Sleep-Wake Rhythm Disorder
Intervention: Lemborexant 2.5 Mg, Lemborexant 5 Mg, Lemborexant 10 Mg, Lemborexant 15 Mg, Lemborexant-matched Placebo
Conditions: Irregular Sleep-Wake Rhythm Disorder
Intervention: Lemborexant 2.5 Mg, Lemborexant 5 Mg, Lemborexant 10 Mg, Lemborexant 15 Mg, Lemborexant-matched Placebo
July 22, 2019
650
NCT01965756
Completed
Completed
Effect of Insulin Sensitizer Metformin on AD Biomarkers
Conditions: Alzheimer's Disease; Vascular Dementia; Dementia; Memory Impairment
Intervention: Metformin, Placebos
Conditions: Alzheimer's Disease; Vascular Dementia; Dementia; Memory Impairment
Intervention: Metformin, Placebos
August 21, 2017
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.