Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Type 1 Diabetes
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NCTID/Status
Study
Last Changed
601
NCT04163874
Not yet recruiting
Not yet recruiting
Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial Pancreas
Conditions: Type 1 Diabetes; Type 1 Diabetes Mellitus; Hyperglycemia, Postprandial
Intervention: Fiasp, Pramlintide Acetate, Placebo, Artificial Pancreas
Conditions: Type 1 Diabetes; Type 1 Diabetes Mellitus; Hyperglycemia, Postprandial
Intervention: Fiasp, Pramlintide Acetate, Placebo, Artificial Pancreas
November 12, 2019
602
NCT00789945
Completed
Completed
Timing of Insulin Before Meals Everyday
Conditions: Type 1 Diabetes
Intervention: Control, Study Arm B
Conditions: Type 1 Diabetes
Intervention: Control, Study Arm B
April 4, 2013
603
NCT00644501
Completed
Completed
Long-Term Treatment Effect of DiaPep277 in Type 1 Diabetes
Conditions: Type 1 Diabetes
Intervention: DiaPep277
Conditions: Type 1 Diabetes
Intervention: DiaPep277
July 10, 2013
604
NCT02464033
Completed
Completed
EDCR Study - Etanercept Diamyd Combination Regimen -Open Trial to Evaluate Safety in Children With Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: GAD-Alum, Vitamin D, Etanercept
Conditions: Diabetes Mellitus, Type 1
Intervention: GAD-Alum, Vitamin D, Etanercept
September 24, 2019
605
NCT02663661
Completed
Completed
Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index
Conditions: Diabetes Mellitus, Type 1
Intervention: Metabolic Challenge Admission, CGM Home Test
Conditions: Diabetes Mellitus, Type 1
Intervention: Metabolic Challenge Admission, CGM Home Test
July 22, 2019
606
NCT00105352
Completed
Completed
Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials
Conditions: Diabetes Mellitus, Type 1
Intervention: Mixed Meal Tolerance Test, Glucagon Stimulation Test
Conditions: Diabetes Mellitus, Type 1
Intervention: Mixed Meal Tolerance Test, Glucagon Stimulation Test
June 1, 2016
607
NCT02685449
Unknown status
Unknown status
Insulin Requirement for Pure-protein Meal in Children With Type 1 Diabetes on Insulin Pumps.
Conditions: Diabetes type1
Intervention: Insulin Glulisine, Insulin Aspart, Insulin Lispro
Conditions: Diabetes type1
Intervention: Insulin Glulisine, Insulin Aspart, Insulin Lispro
July 28, 2016
608
NCT00290979
Completed
Completed
Efficacy and Safety of Insulin Glulisine in Type 1 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 1
Intervention: Insulin Glulisine
Conditions: Diabetes Mellitus, Type 1
Intervention: Insulin Glulisine
August 25, 2009
609
NCT01238406
Completed
Completed
Overnight MD-Logic
Conditions: Type 1 Diabetes
Intervention: MD-logic Artificial Pancreas (MDLAP), Standard Treatment With Insulin Pump
Conditions: Type 1 Diabetes
Intervention: MD-logic Artificial Pancreas (MDLAP), Standard Treatment With Insulin Pump
January 10, 2017
610
NCT02120794
Completed
Completed
August 15, 2018
611
NCT02790645
Completed
Completed
Telemedicine Program in Type 1 Diabetes and CSII
Conditions: Diabetes Mellitus, Type 1
Intervention: Group 2a. Telemedicine Program, Group 1a. Control, Group 1b.Telemedicine Program, Group 2b. Control
Conditions: Diabetes Mellitus, Type 1
Intervention: Group 2a. Telemedicine Program, Group 1a. Control, Group 1b.Telemedicine Program, Group 2b. Control
July 12, 2017
612
NCT00477204
Completed
Completed
Clinical Trial of Zocor (Simvastatin) and Vytorin (Ezetimibe/Simvastatin) in Adolescents With Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus; Dyslipidemia
Intervention: Simvastatin, Ezetimibe/Simvastatin
Conditions: Type 1 Diabetes Mellitus; Dyslipidemia
Intervention: Simvastatin, Ezetimibe/Simvastatin
August 19, 2013
613
NCT01194479
Completed
Completed
Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.
Conditions: Type 1 Diabetes
Conditions: Type 1 Diabetes
February 26, 2016
614
NCT02715193
Completed
Completed
Single-dose Study to Evaluate Safety, Tolerability, and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
Conditions: Type 1 Diabetes Mellitus; Diabetes
Intervention: REMD-477, Placebo Comparator
Conditions: Type 1 Diabetes Mellitus; Diabetes
Intervention: REMD-477, Placebo Comparator
February 6, 2017
615
NCT03845114
Recruiting
Recruiting
Insulin-based Strategies to Prevent Hypoglycemia During Two Types of Exercise
Conditions: Type 1 Diabetes Mellitus
Intervention: Continous Exercise, Interval Exercise, Reduction Of Basal Insulin By 40%, Reduction Of Basal Insulin By 80%
Conditions: Type 1 Diabetes Mellitus
Intervention: Continous Exercise, Interval Exercise, Reduction Of Basal Insulin By 40%, Reduction Of Basal Insulin By 80%
July 2, 2019
616
NCT03473704
Recruiting
Recruiting
Telematic Program for the Treatment of Depression in Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus; Depression
Conditions: Type 1 Diabetes Mellitus; Depression
March 21, 2018
617
NCT00869414
Terminated
Terminated
Glycemic Effects of Morning Only, Evening Only or Twice Daily Insulin Glargine in Patients With Type 1 Diabetes
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Evening Only Administration Of Insulin Glargine, Morning Only Administration Of Insulin Glargine, Split Dose Insulin Glargine
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Evening Only Administration Of Insulin Glargine, Morning Only Administration Of Insulin Glargine, Split Dose Insulin Glargine
May 30, 2017
618
NCT02220257
Unknown status
Unknown status
The Influence of Partial Remission Phase of Type 1 Diabetes on Patient Outcome
Conditions: Diabetes Mellitus Type 1; Remission of Type 1 Diabetes; Chronic Complications of Diabetes
Conditions: Diabetes Mellitus Type 1; Remission of Type 1 Diabetes; Chronic Complications of Diabetes
August 18, 2014
619
NCT02471040
Recruiting
Recruiting
Brain Ketone Metabolism in Type 1 Diabetes
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Beta-hydroxybutyrate, Normal Saline
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Beta-hydroxybutyrate, Normal Saline
August 20, 2018
620
NCT02617654
Recruiting
Recruiting
Liraglutide Effect on Beta-cell Function in C-peptide Positive Type 1 Diabetes
Conditions: Type 1 Diabetes
Intervention: Liraglutide, Placebo For Liraglutide
Conditions: Type 1 Diabetes
Intervention: Liraglutide, Placebo For Liraglutide
April 15, 2019
621
NCT00737763
Withdrawn
Withdrawn
Beta Cell Rescue in New Onset Type 1 Diabetes With Efalizumab
Conditions: Diabetes Mellitus, Type 1
Intervention: Efalizumab, Placebo
Conditions: Diabetes Mellitus, Type 1
Intervention: Efalizumab, Placebo
May 9, 2014
622
NCT00623610
Completed
Completed
Beta-Cell Transplantation in Pre-Uremic Patients With Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: Islet Cell Grafts
Conditions: Diabetes Mellitus, Type 1
Intervention: Islet Cell Grafts
February 19, 2008
623
NCT01098994
Completed
Completed
Haptoglobin Phenotype, Vitamin E and High-density Lipoprotein (HDL) Function in Type 1 Diabetes
Conditions: Type 1 Diabetes; Heart Disease
Intervention: Vitamin E, Dummy Pills
Conditions: Type 1 Diabetes; Heart Disease
Intervention: Vitamin E, Dummy Pills
June 2, 2014
624
NCT03565770
Recruiting
Recruiting
Assessment of Individual Follow-up by Coaching Program for Type 1 Diabetes Children
Conditions: Diabetes type1
Intervention: Individual Coaching, Standard Care
Conditions: Diabetes type1
Intervention: Individual Coaching, Standard Care
February 14, 2019
625
NCT01222078
Terminated
Terminated
Investigating Re-Dosing With Otelixizumab in Adults With Newly-Diagnosed Type 1 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 1
Intervention: Otelixizumab
Conditions: Diabetes Mellitus, Type 1
Intervention: Otelixizumab
July 27, 2017
626
NCT02580877
Completed
Completed
Immune Effects of Oral Insulin in Relatives at Risk for Type 1 Diabetes Mellitus (TN20)
Conditions: Type 1 Diabetes
Intervention: 67.5 Mg Oral Insulin Crystals Daily, 500mg Oral Insulin Crystals Every Other Week
Conditions: Type 1 Diabetes
Intervention: 67.5 Mg Oral Insulin Crystals Daily, 500mg Oral Insulin Crystals Every Other Week
May 13, 2019
627
NCT03039933
Recruiting
Recruiting
Intervention to Reduce Fear of Hypoglycemia and Optimize Type 1 Diabetes Outcomes
Conditions: Type1diabetes; Fear of Hypoglycemia
Intervention: Fear Of Hypoglycemia, Treatment As Usual
Conditions: Type1diabetes; Fear of Hypoglycemia
Intervention: Fear Of Hypoglycemia, Treatment As Usual
June 11, 2019
628
NCT02928016
Completed
Completed
Effectiveness of Carbohydrate Counting Method With Mixed Meals
Conditions: Type 1 Diabetes
Conditions: Type 1 Diabetes
October 8, 2016
629
NCT00575159
Completed
Completed
A Study to Assess the Safety of Single Doses of GSK189075 in Subjects With Type 1 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 1
Intervention: GSK189075, Placebo
Conditions: Diabetes Mellitus, Type 1
Intervention: GSK189075, Placebo
September 8, 2017
630
NCT03143816
Unknown status
Unknown status
Study Comparing Prandial Insulin Aspart vs. Technosphere Insulin in Patients With Type 1 Diabetes on Multiple Daily Injections: Investigator-Initiated A Real-life Pilot Study—STAT Study
Conditions: Diabetes Mellitus, Type 1
Intervention: Technosphere Insulin
Conditions: Diabetes Mellitus, Type 1
Intervention: Technosphere Insulin
November 7, 2017
631
NCT02620553
Completed
Completed
Primary Intervention With Mucosal Insulin
Conditions: Type 1 Diabetes
Intervention: Human Insulin, Oral Placebo
Conditions: Type 1 Diabetes
Intervention: Human Insulin, Oral Placebo
April 19, 2017
632
NCT03260998
Unknown status
Unknown status
ECG Changes in Children and Adolescents With Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: Electrocardiogram
Conditions: Diabetes Mellitus, Type 1
Intervention: Electrocardiogram
August 27, 2017
633
NCT02760303
Completed
Completed
Reducing Stress in Adolescents and Young Adults With Type 1 Diabetes to Improve Diabetes Care
Conditions: Type 1 Diabetes
Intervention: Cognitive Behavioral Therapy, Mindfulness Based Stress Reduction, Diabetes Support And Education
Conditions: Type 1 Diabetes
Intervention: Cognitive Behavioral Therapy, Mindfulness Based Stress Reduction, Diabetes Support And Education
May 31, 2017
634
NCT03936829
Recruiting
Recruiting
Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes
Conditions: Lipodystrophy Acquired; Type1diabetes
Intervention: Cyclophosphamide
Conditions: Lipodystrophy Acquired; Type1diabetes
Intervention: Cyclophosphamide
May 20, 2019
635
NCT00678886
Completed
Completed
Trial of Otelixizumab for Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-1
Conditions: Diabetes Mellitus, Type 1
Intervention: Otelixizumab Infusion Plus Physician Determined Standard Of Care, Placebo Infusion Plus Physician Determined Standard Of Care
Conditions: Diabetes Mellitus, Type 1
Intervention: Otelixizumab Infusion Plus Physician Determined Standard Of Care, Placebo Infusion Plus Physician Determined Standard Of Care
September 5, 2017
636
NCT00451321
Terminated
Terminated
TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM)
Conditions: Diabetes Mellitus, Type 1
Intervention: Otelixizumab
Conditions: Diabetes Mellitus, Type 1
Intervention: Otelixizumab
October 11, 2017
637
NCT04026750
Recruiting
Recruiting
Insulin Tolerance Test Study to Assess Safety, Tolerability and Pharmacodynamics of Pitolisant in Patients With Type 1 Diabetes
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Pitolisant
Conditions: Type 1 Diabetes; Hypoglycemia
Intervention: Pitolisant
July 17, 2019
638
NCT04186195
Not yet recruiting
Not yet recruiting
Psychosocial Factors Affecting Glycemic Control in Children and Adolescents With Type 1 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 1
Conditions: Diabetes Mellitus, Type 1
December 2, 2019
639
NCT04049110
Not yet recruiting
Not yet recruiting
Dapagliflozin in Physical Exercise in Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: Forxiga 10mg, Placebo
Conditions: Diabetes Mellitus, Type 1
Intervention: Forxiga 10mg, Placebo
August 19, 2019
640
NCT01638299
Completed
Completed
Study Assessing an Insulin Pump-controlling Algorithm to Minimize Hypo and Hyper in Type 1 During CRC Setting
Conditions: Type 1 Diabetes Mellitus
Intervention: Hypo-Hyper Minimizer (HHM) System
Conditions: Type 1 Diabetes Mellitus
Intervention: Hypo-Hyper Minimizer (HHM) System
September 19, 2012
641
NCT01922817
Completed
Completed
DPP4inhibitors in Type 1 Diabetes
Conditions: Type 1 Diabetes; Hypoglycaemia
Conditions: Type 1 Diabetes; Hypoglycaemia
October 11, 2019
642
NCT02814123
Recruiting
Recruiting
Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: 24-hour Inpatient Intervention
Conditions: Diabetes Mellitus, Type 1
Intervention: 24-hour Inpatient Intervention
January 4, 2018
643
NCT02351466
Completed
Completed
Type 1 Diabetes and the Brain in Children
Conditions: Diabetes Mellitus, Type 1
Intervention: Observational
Conditions: Diabetes Mellitus, Type 1
Intervention: Observational
May 5, 2019
644
NCT03481374
Completed
Completed
Cardiovascular Autonomic Neuropathy in Patients With Type 1 Diabetes Mellitus.
Conditions: Diabetes Mellitus, Type 1
Intervention: Autonomic Function Testing
Conditions: Diabetes Mellitus, Type 1
Intervention: Autonomic Function Testing
April 14, 2018
645
NCT00999375
Completed
Completed
Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)
Conditions: Type I Diabetes
Intervention: Education, Problem Solving, Social Learning, Behavior Modification
Conditions: Type I Diabetes
Intervention: Education, Problem Solving, Social Learning, Behavior Modification
November 27, 2019
646
NCT02485327
Completed
Completed
PK and PD Within-Subject Variability of a Single Dose of Afrezza Inhaled Technosphere Insulin in Patients With Diabetes Mellitus Type 1 (T1DM)
Conditions: Type 1 Diabetes Mellitus
Intervention: Technosphere Insulin SAR439065 Afrezza®
Conditions: Type 1 Diabetes Mellitus
Intervention: Technosphere Insulin SAR439065 Afrezza®
March 13, 2017
647
NCT02162004
Terminated
Terminated
August 30, 2016
648
NCT00946517
Terminated
Terminated
Impaired Family Dynamics Leads to Non Compliance in Type I Diabetes
Conditions: Type 1 Diabetes
Intervention: Questionnaires
Conditions: Type 1 Diabetes
Intervention: Questionnaires
May 14, 2015
649
NCT04161976
Not yet recruiting
Not yet recruiting
A Study of LY900027 Given by Insulin Pump to Participants With Type 1 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 1
Intervention: LY900027, Insulin Lispro
Conditions: Diabetes Mellitus, Type 1
Intervention: LY900027, Insulin Lispro
December 2, 2019
650
NCT03156179
Completed
Completed
Study of Calcium Metabolism in Teenage Girls With Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: Calcium Isotope Analysis
Conditions: Diabetes Mellitus, Type 1
Intervention: Calcium Isotope Analysis
May 15, 2017
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
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Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
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all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
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Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
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Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
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Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
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Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
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Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
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unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.