Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Placebo
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NCTID/Status
Study
Last Changed
1301
NCT03536754
Active, not recruiting
Active, not recruiting
A Study of CCX140-B in Subjects With FSGS
Conditions: FSGS; Focal Segmental Glomerulosclerosis; Glomerulosclerosis
Intervention: Placebo, CCX140-B
Conditions: FSGS; Focal Segmental Glomerulosclerosis; Glomerulosclerosis
Intervention: Placebo, CCX140-B
August 19, 2019
1302
NCT02579772
Completed
Completed
Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow Obstruction
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: N-acetylcysteine, Placebo
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: N-acetylcysteine, Placebo
May 15, 2018
1303
NCT02874937
Completed
Completed
A Proof of Principal Study of Atomoxetine for the Prevention of Vasovagal Syncope
Conditions: Syncope, Vasovagal
Intervention: Atomoxetine, Matching Placebo
Conditions: Syncope, Vasovagal
Intervention: Atomoxetine, Matching Placebo
May 15, 2019
1304
NCT01901887
Terminated
Terminated
The Better Resiliency Among Veterans With Omega-3's (BRAVO) Study
Conditions: Suicide
Intervention: Study Juice, Placebo Juice
Conditions: Suicide
Intervention: Study Juice, Placebo Juice
June 9, 2018
1305
NCT03598140
Recruiting
Recruiting
Sildenafil Treatment for Mild TBI
Conditions: Vascular System Injuries; Concussion, Brain; Post-Concussion Syndrome
Intervention: Sildenafil Citrate, Placebo Oral Capsule
Conditions: Vascular System Injuries; Concussion, Brain; Post-Concussion Syndrome
Intervention: Sildenafil Citrate, Placebo Oral Capsule
September 6, 2019
1306
NCT03007329
Recruiting
Recruiting
Effects of Combined Dapagliflozin and Exenatide Versus Dapagliflozin and Placebo on Ectopic Lipids in Patients With Uncontrolled Type 2 Diabetes Mellitus.
Conditions: Steatosis, Liver; Type2 Diabetes
Intervention: Exenatide, Exenatide Matching Placebo, Dapagliflozin
Conditions: Steatosis, Liver; Type2 Diabetes
Intervention: Exenatide, Exenatide Matching Placebo, Dapagliflozin
March 7, 2019
1307
NCT01227265
Completed
Completed
Placebo Controlled Study of Preladenant in Participants With Moderate to Severe Parkinson's Disease (P07037)
Conditions: Parkinson Disease; Idiopathic Parkinson Disease; Idiopathic Parkinson's Disease
Intervention: Preladenant, Placebo
Conditions: Parkinson Disease; Idiopathic Parkinson Disease; Idiopathic Parkinson's Disease
Intervention: Preladenant, Placebo
August 24, 2018
1308
NCT01890135
Completed
Completed
Zibotentan, an Endothelin Receptor Antagonist, Patients With Intermittent Claudication
Conditions: Peripheral Arterial Disease; Intermittent Claudication
Intervention: Zibotentan (ZD4054), Placebo
Conditions: Peripheral Arterial Disease; Intermittent Claudication
Intervention: Zibotentan (ZD4054), Placebo
August 1, 2016
1309
NCT02900131
Completed
Completed
Efficacy, Safety and Dose Finding Trial of Topical Jaungo Application in Atopic Dermatitis Patients
Conditions: Dermatitis, Atopic
Intervention: Jaungo, Placebo
Conditions: Dermatitis, Atopic
Intervention: Jaungo, Placebo
May 30, 2017
1310
NCT02235077
Completed
Completed
Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure
Conditions: Heart Failure
Intervention: Spironolactone, Placebo
Conditions: Heart Failure
Intervention: Spironolactone, Placebo
May 22, 2017
1311
NCT00745914
Completed
Completed
Peroxisome Proliferator-Activated Receptor-gamma (PPAR-gamma) Agonist in Diabetic End-Stage Renal Disease Patients
Conditions: Endstage Renal Disease; Diabetes
Intervention: Pioglitazone, Placebo Comparator
Conditions: Endstage Renal Disease; Diabetes
Intervention: Pioglitazone, Placebo Comparator
January 7, 2017
1312
NCT03082755
Recruiting
Recruiting
Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
Conditions: Alzheimer Disease
Intervention: Gabapentin Enacarbil, Placebo Oral Tablet
Conditions: Alzheimer Disease
Intervention: Gabapentin Enacarbil, Placebo Oral Tablet
October 23, 2019
1313
NCT01644877
Completed
Completed
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract Parainfluenza Infection on Supplemental Oxygen
Conditions: Parainfluenza
Intervention: DAS181 Dry Powder, Formulation F02, Lactose Placebo
Conditions: Parainfluenza
Intervention: DAS181 Dry Powder, Formulation F02, Lactose Placebo
September 21, 2017
1314
NCT00175890
Completed
Completed
A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.
Conditions: Epilepsy, Partial
Intervention: Levetiracetam, Placebo
Conditions: Epilepsy, Partial
Intervention: Levetiracetam, Placebo
July 6, 2015
1315
NCT03927885
Recruiting
Recruiting
Open Labeled Placebo in Reducing Cancer Related Fatigue in Patients With Advanced Cancer
Conditions: Advanced Malignant Solid Neoplasm; Cancer Fatigue; Metastatic Malignant Solid Neoplasm; Pain; Recurrent Malignant Solid Neoplasm
Intervention: Placebo, Quality-of-Life Assessment, Questionnaire Administration, Waiting List
Conditions: Advanced Malignant Solid Neoplasm; Cancer Fatigue; Metastatic Malignant Solid Neoplasm; Pain; Recurrent Malignant Solid Neoplasm
Intervention: Placebo, Quality-of-Life Assessment, Questionnaire Administration, Waiting List
September 25, 2019
1316
NCT00431951
Completed
Completed
Phase I, Escalating, Multiple-Dose, ST-246 Safety, Tolerability and Pharmacokinetics 21-Day Trial in Healthy Volunteers
Conditions: Healthy
Intervention: ST-246, Placebo
Conditions: Healthy
Intervention: ST-246, Placebo
July 25, 2017
1317
NCT03316729
Withdrawn
Withdrawn
DS-9231 in Intermediate-risk (Sub-massive) Acute Pulmonary Embolism (PE)
Conditions: Pulmonary Embolism
Intervention: DS-9231, Placebo
Conditions: Pulmonary Embolism
Intervention: DS-9231, Placebo
December 20, 2018
1318
NCT03422796
Completed
Completed
The Effect of Sumatriptan and Placebo Injection on Cilostazol Induced Headache
Conditions: Migraine
Intervention: Cilostazol 200mg, SUMAtriptan 6 MG/ML, Placebo
Conditions: Migraine
Intervention: Cilostazol 200mg, SUMAtriptan 6 MG/ML, Placebo
June 4, 2019
1319
NCT03713801
Recruiting
Recruiting
Impact of Metformin on Immunity
Conditions: Aging; Vaccine Response Impaired
Intervention: Metformin, Placebo
Conditions: Aging; Vaccine Response Impaired
Intervention: Metformin, Placebo
February 15, 2019
1320
NCT03111810
Unknown status
Unknown status
Targeting Iatrogenic Cushing's Syndrome With 11β-hydroxysteroid Dehydrogenase Type 1 Inhibition
Conditions: Iatrogenic Cushing's Disease
Intervention: AZD4017 And Prednisolone, Placebo Oral Tablet And Prednisolone
Conditions: Iatrogenic Cushing's Disease
Intervention: AZD4017 And Prednisolone, Placebo Oral Tablet And Prednisolone
October 5, 2017
1321
NCT00769119
Completed
Completed
A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis
Conditions: Bronchiectasis
Intervention: AZD9668, Placebo
Conditions: Bronchiectasis
Intervention: AZD9668, Placebo
August 14, 2012
1322
NCT02940509
Recruiting
Recruiting
Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
Conditions: Chronic Pain
Intervention: Ketamine Plus Magnesium Sulfate, Placebo
Conditions: Chronic Pain
Intervention: Ketamine Plus Magnesium Sulfate, Placebo
July 8, 2019
1323
NCT03098368
Unknown status
Unknown status
Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors
Conditions: Nocturnal Hypokinesia
Intervention: Rotigotine, Placebo
Conditions: Nocturnal Hypokinesia
Intervention: Rotigotine, Placebo
March 27, 2017
1324
NCT00294684
Completed
Completed
A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy
Conditions: Biliary Atresia
Intervention: Corticosteroids, Placebo
Conditions: Biliary Atresia
Intervention: Corticosteroids, Placebo
October 11, 2019
1325
NCT00235820
Completed
Completed
Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Conditions: Psoriasis
Intervention: Adalimumab, MTX, Placebo Adalimumab, Placebo MTX
Conditions: Psoriasis
Intervention: Adalimumab, MTX, Placebo Adalimumab, Placebo MTX
July 15, 2008
1326
NCT03446807
Not yet recruiting
Not yet recruiting
Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism
Conditions: Parkinson Disease; Multiple System Atrophy; Progressive Supranuclear Palsy
Intervention: Droxidopa, Placebo Oral Tablet
Conditions: Parkinson Disease; Multiple System Atrophy; Progressive Supranuclear Palsy
Intervention: Droxidopa, Placebo Oral Tablet
December 7, 2019
1327
NCT01641159
Completed
Completed
Study of Buspirone for Relapse-Prevention in Adults With Cocaine Dependence
Conditions: Cocaine Dependence
Intervention: Buspirone, Placebo
Conditions: Cocaine Dependence
Intervention: Buspirone, Placebo
December 18, 2014
1328
NCT03614052
Recruiting
Recruiting
Tamsulosin as Adjuvant Treatment Prior to Endoscopic Ureterolithotomy
Conditions: Ureterolithiasis; Ureteral Calculi; Urolithiasis
Intervention: Tamsulosin Hydrochloride 0.4 Milligrams, Placebo Oral Tablet
Conditions: Ureterolithiasis; Ureteral Calculi; Urolithiasis
Intervention: Tamsulosin Hydrochloride 0.4 Milligrams, Placebo Oral Tablet
April 24, 2019
1329
NCT00409409
Completed
Completed
Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis
Conditions: Allergy
Intervention: 300 IR Grass Pollen Allergen Extract Tablet, Placebo Tablet
Conditions: Allergy
Intervention: 300 IR Grass Pollen Allergen Extract Tablet, Placebo Tablet
April 18, 2016
1330
NCT01971801
Completed
Completed
Vitamin D Supplementation in Older Adults With Urinary Incontinence
Conditions: Urinary Incontinence; Vitamin D Deficiency
Intervention: Vitamin D3 50,000 IU, Placebo
Conditions: Urinary Incontinence; Vitamin D Deficiency
Intervention: Vitamin D3 50,000 IU, Placebo
March 7, 2018
1331
NCT02778477
Terminated
Terminated
Topical Multiple Ascending Dose Study for PF-06423264
Conditions: Normal Healthy
Intervention: PF-06423264, Placebo
Conditions: Normal Healthy
Intervention: PF-06423264, Placebo
June 20, 2017
1332
NCT03521960
Recruiting
Recruiting
Buspirone for Opioid Tapering
Conditions: Opioid-Related Disorders; Dependency (Psychology); Pain, Chronic; Opiate Withdrawal Syndrome
Intervention: Buspirone Oral Capsule, Placebo Oral Capsule
Conditions: Opioid-Related Disorders; Dependency (Psychology); Pain, Chronic; Opiate Withdrawal Syndrome
Intervention: Buspirone Oral Capsule, Placebo Oral Capsule
July 12, 2019
1333
NCT01274897
Completed
Completed
A Multi-center, Observer-blind, Placebo-controlled, Randomized Study to Evaluate the Immunogenicity and Safety of MenACWY in Adolescents and Adults in Korea
Conditions: Meningococcal Disease; Meningococcal Meningitis
Intervention: Novartis MenACWY-CRM, Saline Placebo
Conditions: Meningococcal Disease; Meningococcal Meningitis
Intervention: Novartis MenACWY-CRM, Saline Placebo
September 17, 2012
1334
NCT01782755
Completed
Completed
Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial
Conditions: Ventilator Associated Pneumonia (VAP); Other Infections; Antibiotic-Associated Diarrhea; C-Difficile; Duration of Mechanical Ventilation; Length of ICU Stay; Length of Hospital Stay; ICU and Hospital Mortality
Intervention: L. Rhamnosus GG - Probiotic, Placebo - Microcrystalline Cellulose
Conditions: Ventilator Associated Pneumonia (VAP); Other Infections; Antibiotic-Associated Diarrhea; C-Difficile; Duration of Mechanical Ventilation; Length of ICU Stay; Length of Hospital Stay; ICU and Hospital Mortality
Intervention: L. Rhamnosus GG - Probiotic, Placebo - Microcrystalline Cellulose
August 26, 2019
1335
NCT00430963
Completed
Completed
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines
Conditions: Glabellar Frown Lines
Intervention: IncobotulinumtoxinA (Xeomin) (20 Units), Placebo
Conditions: Glabellar Frown Lines
Intervention: IncobotulinumtoxinA (Xeomin) (20 Units), Placebo
October 25, 2011
1336
NCT02158936
Terminated
Terminated
A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)
Conditions: Thrombocytopaenia
Intervention: Eltrombopag, Azacitidine, Placebo, Placebo
Conditions: Thrombocytopaenia
Intervention: Eltrombopag, Azacitidine, Placebo, Placebo
November 12, 2017
1337
NCT00781820
Completed
Completed
Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste
Conditions: Onychomycosis
Intervention: Bifonazole Cream 1%, Placebo Cream
Conditions: Onychomycosis
Intervention: Bifonazole Cream 1%, Placebo Cream
June 9, 2013
1338
NCT04098302
Recruiting
Recruiting
Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy
Conditions: Alcohol Use Disorder
Intervention: Dutasteride Capsules, Placebo Capsules
Conditions: Alcohol Use Disorder
Intervention: Dutasteride Capsules, Placebo Capsules
October 18, 2019
1339
NCT02754258
Unknown status
Unknown status
The Effects of Methylphenidate on Energy Intake and Energy Expenditure
Conditions: Obesity
Intervention: MPH, Placebo
Conditions: Obesity
Intervention: MPH, Placebo
August 2, 2017
1340
NCT01045577
Completed
Completed
A Double-blind, Placebo-controlled, Randomized, Parallel-group Study to Evaluate the Activity of Oral AB1010 in Adults Patients With Moderate to Severe Chronic Plaque Psoriasis
Conditions: Psoriasis
Intervention: Masitinib, Masitinib, Placebo
Conditions: Psoriasis
Intervention: Masitinib, Masitinib, Placebo
December 6, 2018
1341
NCT03339635
Recruiting
Recruiting
Short-term Testosterone Replacement in Testicular Cancer Survivors
Conditions: Testicular Cancer
Intervention: Androgel (Testosterone Gel), Placebo Gel
Conditions: Testicular Cancer
Intervention: Androgel (Testosterone Gel), Placebo Gel
October 22, 2019
1342
NCT03068975
Recruiting
Recruiting
Alvimopan Use in Polytraumatized Patients
Conditions: Post Operative Ileus
Intervention: Alvimopan, Placebo
Conditions: Post Operative Ileus
Intervention: Alvimopan, Placebo
July 24, 2019
1343
NCT03887416
Recruiting
Recruiting
Effect of Dapagliflozin on Nighttime Blood Pressure in Type 2 Diabetes
Conditions: Type2 Diabetes
Intervention: Dapagliflozin 10 MG Oral Tablet [Farxiga], Placebo Oral Tablet
Conditions: Type2 Diabetes
Intervention: Dapagliflozin 10 MG Oral Tablet [Farxiga], Placebo Oral Tablet
August 30, 2019
1344
NCT00239681
Terminated
Terminated
JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
Conditions: Elevated High-sensitivity C-Reactive Protein (hsCRP)
Intervention: Rosuvastatin, Placebo
Conditions: Elevated High-sensitivity C-Reactive Protein (hsCRP)
Intervention: Rosuvastatin, Placebo
February 6, 2014
1345
NCT02088632
Terminated
Terminated
Botulinum Toxin for the Treatment of Trigeminal Neuralgia
Conditions: Trigeminal Neuralgia
Intervention: Incobotulinumtoxina, Placebo Comparator
Conditions: Trigeminal Neuralgia
Intervention: Incobotulinumtoxina, Placebo Comparator
May 19, 2017
1346
NCT00421538
Completed
Completed
Randomized Controlled Trial of Anticoagulation vs. Placebo for a First Symptomatic Isolated Distal Deep-vein Thrombosis (IDDVT)
Conditions: Distal (Calf) Deep-vein Thrombosis
Intervention: Nadroparine Calcium, Placebo
Conditions: Distal (Calf) Deep-vein Thrombosis
Intervention: Nadroparine Calcium, Placebo
May 3, 2018
1347
NCT01298570
Active, not recruiting
Active, not recruiting
Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer
Conditions: Colorectal Cancer Metastatic
Intervention: Regorafenib (BAY 73-4506), FOLFIRI, Placebo, FOLFIRI
Conditions: Colorectal Cancer Metastatic
Intervention: Regorafenib (BAY 73-4506), FOLFIRI, Placebo, FOLFIRI
June 28, 2019
1348
NCT02478580
Completed
Completed
Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients
Conditions: Obesity; Premature Recovery From Anesthesia
Intervention: Nuvigil, Placebo
Conditions: Obesity; Premature Recovery From Anesthesia
Intervention: Nuvigil, Placebo
December 3, 2018
1349
NCT00632866
Completed
Completed
Hydroxychloroquine Versus Placebo in Primary Sjögren's Syndrome
Conditions: Primary Sjögren's Syndrome
Intervention: Hydroxychloroquine, Placebo
Conditions: Primary Sjögren's Syndrome
Intervention: Hydroxychloroquine, Placebo
July 1, 2012
1350
NCT03000075
Completed
Completed
BI 655066 (Risankizumab) Compared to Placebo in Japanese Patients With Moderate to Severe Chronic Plaque Psoriasis
Conditions: Psoriasis
Intervention: Risankizumab, Placebo For Risankizumab
Conditions: Psoriasis
Intervention: Risankizumab, Placebo For Risankizumab
May 7, 2019
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.