Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Placebo
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Recruiting
Conditions: Muscular Dystrophy, Duchenne
Intervention: SRP-9001, Placebo
Recruiting
Conditions: Melanoma
Intervention: Nivolumab, Placebo
Recruiting
Conditions: Primary IgA Nephropathy
Intervention: Nefecon, Placebo Oral Capsule
Completed
Conditions: Brain Imaging of Placebo Analgesia
Intervention: Placebo Instructions, Control Condition
Recruiting
Conditions: Recurrent Pregnancy Loss
Intervention: Hydroxychloroquine, Hydroxychloroquine Placebo
Recruiting
Conditions: Diabetes Mellitus, Type 2
Intervention: Tadalafil, Placebo
Completed
Conditions: Safety
Intervention: NAVX-010, Placebo
Completed
Conditions: Muscle Soreness
Intervention: Ibuprofen 400 Mg, Placebo
Recruiting
Conditions: Crohn Disease; Ulcerative Colitis; Fatigue; Remission
Intervention: 5-HTP, Placebo Oral Capsule
Not yet recruiting
Conditions: Primary Antiphospholipid Syndrome
Intervention: Hydroxychloroquine, Placebo
Completed
Conditions: Ischemic Heart Disease
Intervention: Eplerenone, Placebo Or Sugar Pill
Completed
Conditions: Malaria
Intervention: Chloroquine, Placebo
Withdrawn
Conditions: Type2 Diabetes Mellitus; Cardiovascular Diseases
Intervention: Canagliflozin 300mg, Placebo
Completed
Conditions: Menopausal Syndrome; Hot Flashes
Intervention: Sulpiride Use, Placebo
Recruiting
Conditions: PCDH19-Related Epilepsy
Intervention: Ganaxolone, Placebo
Recruiting
Conditions: Male Infertility Due to Hypospermatogenesis
Intervention: Omega 3 Fatty Acid, Placebo Oral Capsule
Active, not recruiting
Conditions: Current Smoker; Former Smoker; Multiple Pulmonary Nodules; Tobacco Use Disorder
Intervention: Aspirin, Laboratory Biomarker Analysis, Placebo
Not yet recruiting
Conditions: Crohn Disease; Inflammatory Bowel Diseases; Cannabis
Intervention: Cannabidiol, Placebo Oral Capsule
Unknown status
Conditions: Endothelial Function; Blood Pressure; Lipid Metabolism
Intervention: WAK2017, Placebo
Unknown status
Conditions: Cervical Intraepithelial Neoplasia
Intervention: GX-188E, Placebo
Recruiting
Conditions: Implantation Failure; Infertility, Female; Vaginal Flora Imbalance
Intervention: Vivag Plus, Placebo - Cap
Unknown status
Conditions: Attention Deficit Disorder With Hyperactivity
Completed
Conditions: Acute Ischemic Stroke; Thrombotic Disease
Intervention: DS-1040b, Placebo
Recruiting
Conditions: Ulcerative Colitis in Remission
Intervention: Curcumin, Placebo
Completed
Conditions: Major Depressive Disorder
Intervention: Anyu Peibo, Placebo
Completed
Conditions: Idiopathic Pulmonary Fibrosis; Cough
Intervention: Gefapixant First, Then Placebo, Placebo First, Then Gefapixant
Unknown status
Conditions: Alternating Hemiplegia of Childhood
Intervention: Triheptanoin, Placebo
Terminated
Conditions: Growth Hormone Deficiency
Intervention: TV-1106, Placebo
Recruiting
Conditions: HPV Infection; HPV-Related Cervical Carcinoma
Recruiting
Conditions: Clostridium Difficile Infection
Intervention: SER-109, Placebo
Completed
Conditions: Prurigo Nodularis
Intervention: Serlopitant, Placebo
Completed
Conditions: Asthma
Intervention: GW642444M, Placebo
Withdrawn
Conditions: Progressive Familial Intrahepatic Cholestasis (PFIC)
Intervention: Maralixibat, Placebo
Completed
Conditions: Uterine Fibroids
Intervention: Relugolix, Relugolix Placebo
Recruiting
Conditions: Ulcerative Colitis
Intervention: RO7049665, Placebo
Recruiting
Conditions: Chronic Hepatitis B
Intervention: Antroquinonol Capsule 100mg, Antroquinonol Capsule 200mg, Placebo Oral Capsule
Completed
Conditions: Sore Throat
Intervention: Benzocaine 8 Mg, Placebo
Completed
Conditions: IBD
Intervention: AKB-4924, Placebo
Active, not recruiting
Conditions: Sickle Cell Disease
Intervention: Ticagrelor, Placebo
Completed
Conditions: Asthma
Recruiting
Conditions: CDKL5 Deficiency Disorder
Intervention: Ganaxolone, Placebo
Completed
Conditions: Celiac Disease; Non-celiac Gluten Sensitivity
Intervention: Gluten Challenge, Placebo Challenge
Not yet recruiting
Conditions: Urinary Catheterization; Thoracic Surgery; Thoracic Epidural Analgesia
Intervention: Tamsulosin Hydrochloride, Placebos
Completed
Conditions: Clostridium Difficile
Intervention: SER-109, Placebo
Recruiting
Conditions: Fatigue Symptom
Intervention: DA-5515, Placebo Of DA-5515
Completed
Conditions: HELICOBACTER INFECTION
Intervention: Pylopass, Placebo
Completed
Conditions: Postoperative Pain
Intervention: Ketamine, Placebo
Completed
Conditions: Pulmonary Hypertension
Intervention: Macitentan, Placebo
Not yet recruiting
Conditions: Cardiogenic Shock
Intervention: Levosimendan 2.5 MG/ML Injectable Solution, Placebo
Completed
Conditions: Primary Sjögren's Syndrome
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Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Examples:
97-h-0197
ia0006
actg 076
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
There are three types of studies available in ClinicalTrials.gov:
Observational:
Expanded Access:
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help Topics:
Basic Search:
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Open recruitment status values:
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Studies With Results, or
Studies Without Results
Observational, or
Expanded Access
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
Refine Search:
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
For example:
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.