Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Placebo
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NCTID/Status
Study
Last Changed
201
NCT02491879
Unknown status
Unknown status
Ketoprofen Gel vs Placebo in Low Back Pain
Conditions: Mechanical Low Back Pain
Intervention: Ketoprofen, Placebo
Conditions: Mechanical Low Back Pain
Intervention: Ketoprofen, Placebo
December 2, 2015
202
NCT03655522
Completed
Completed
NAVX-010-Phase I Tolerability and Pharmacokinetic Study in Healthy Male Subjects
Conditions: Safety
Intervention: NAVX-010, Placebo
Conditions: Safety
Intervention: NAVX-010, Placebo
August 30, 2018
203
NCT03769116
Recruiting
Recruiting
A Randomized, Double-blind, Placebo-controlled Study of SRP-9001 for Duchenne Muscular Dystrophy (DMD)
Conditions: Muscular Dystrophy, Duchenne
Intervention: SRP-9001, Placebo
Conditions: Muscular Dystrophy, Duchenne
Intervention: SRP-9001, Placebo
August 23, 2019
204
NCT04099251
Not yet recruiting
Not yet recruiting
Effectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C Melanoma
Conditions: Melanoma
Intervention: Nivolumab, Placebo
Conditions: Melanoma
Intervention: Nivolumab, Placebo
September 20, 2019
205
NCT03574948
Recruiting
Recruiting
5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores
Conditions: Crohn Disease; Ulcerative Colitis; Fatigue; Remission
Intervention: 5-HTP, Placebo Oral Capsule
Conditions: Crohn Disease; Ulcerative Colitis; Fatigue; Remission
Intervention: 5-HTP, Placebo Oral Capsule
May 24, 2019
206
NCT02601989
Recruiting
Recruiting
Effects on Insulin Resistance With Tadalafil in Type 2 Diabetes - a Double-blind, Placebo-controlled Crossover Study
Conditions: Diabetes Mellitus, Type 2
Intervention: Tadalafil, Placebo
Conditions: Diabetes Mellitus, Type 2
Intervention: Tadalafil, Placebo
November 1, 2018
207
NCT01409538
Completed
Completed
Brain Imaging and Pain: Analysis of Placebo Analgesia
Conditions: Brain Imaging of Placebo Analgesia
Intervention: Placebo Instructions, Control Condition
Conditions: Brain Imaging of Placebo Analgesia
Intervention: Placebo Instructions, Control Condition
March 19, 2015
208
NCT03228992
Completed
Completed
Ibuprofen Versus Placebo For Muscle Soreness
Conditions: Muscle Soreness
Intervention: Ibuprofen 400 Mg, Placebo
Conditions: Muscle Soreness
Intervention: Ibuprofen 400 Mg, Placebo
August 2, 2017
209
NCT03540810
Not yet recruiting
Not yet recruiting
Hydroxychloroquine Versus Placebo: Impact on Thrombotic Relapse in Primary Antiphospholipid Syndrome
Conditions: Primary Antiphospholipid Syndrome
Intervention: Hydroxychloroquine, Placebo
Conditions: Primary Antiphospholipid Syndrome
Intervention: Hydroxychloroquine, Placebo
May 28, 2018
210
NCT02698748
Completed
Completed
Evaluating the Role of Chloroquine for Malaria Elimination
Conditions: Malaria
Intervention: Chloroquine, Placebo
Conditions: Malaria
Intervention: Chloroquine, Placebo
February 6, 2018
211
NCT03190798
Withdrawn
Withdrawn
Effects of Canagliflozin on Intravascular Volume and Hemodynamics
Conditions: Type2 Diabetes Mellitus; Cardiovascular Diseases
Intervention: Canagliflozin 300mg, Placebo
Conditions: Type2 Diabetes Mellitus; Cardiovascular Diseases
Intervention: Canagliflozin 300mg, Placebo
October 10, 2017
212
NCT00187889
Completed
Completed
EWISE: Study of Eplerenone in Women With Chest Pain, Coronary Vascular Dysfunction and Evidence of Myocardial Ischemia
Conditions: Ischemic Heart Disease
Intervention: Eplerenone, Placebo Or Sugar Pill
Conditions: Ischemic Heart Disease
Intervention: Eplerenone, Placebo Or Sugar Pill
August 7, 2013
213
NCT03865732
Recruiting
Recruiting
Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)
Conditions: PCDH19-Related Epilepsy
Intervention: Ganaxolone, Placebo
Conditions: PCDH19-Related Epilepsy
Intervention: Ganaxolone, Placebo
October 14, 2019
214
NCT03634644
Recruiting
Recruiting
Omega-3 PUFA for Treatment of Patients With Idiopathic Oligoasthenoteratospermia
Conditions: Male Infertility Due to Hypospermatogenesis
Intervention: Omega 3 Fatty Acid, Placebo Oral Capsule
Conditions: Male Infertility Due to Hypospermatogenesis
Intervention: Omega 3 Fatty Acid, Placebo Oral Capsule
March 26, 2019
215
NCT02749747
Completed
Completed
Sulpiride Versus Placebo for Reducting Hot Flushes During Climacteric
Conditions: Menopausal Syndrome; Hot Flashes
Intervention: Sulpiride Use, Placebo
Conditions: Menopausal Syndrome; Hot Flashes
Intervention: Sulpiride Use, Placebo
January 11, 2019
216
NCT03467620
Not yet recruiting
Not yet recruiting
Cannabidiol Usage as an Adjunct Therapy for Crohn's Disease
Conditions: Crohn Disease; Inflammatory Bowel Diseases; Cannabis
Intervention: Cannabidiol, Placebo Oral Capsule
Conditions: Crohn Disease; Inflammatory Bowel Diseases; Cannabis
Intervention: Cannabidiol, Placebo Oral Capsule
March 16, 2018
217
NCT03287518
Unknown status
Unknown status
Evaluation of the Benefit and Tolerability of WAK2017 on Endothelial Function, Blood Pressure and Lipid Profile
Conditions: Endothelial Function; Blood Pressure; Lipid Metabolism
Intervention: WAK2017, Placebo
Conditions: Endothelial Function; Blood Pressure; Lipid Metabolism
Intervention: WAK2017, Placebo
November 8, 2017
218
NCT02169271
Active, not recruiting
Active, not recruiting
Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules
Conditions: Current Smoker; Former Smoker; Multiple Pulmonary Nodules; Tobacco Use Disorder
Intervention: Aspirin, Laboratory Biomarker Analysis, Placebo
Conditions: Current Smoker; Former Smoker; Multiple Pulmonary Nodules; Tobacco Use Disorder
Intervention: Aspirin, Laboratory Biomarker Analysis, Placebo
January 16, 2019
219
NCT03843112
Recruiting
Recruiting
Modulating the Vaginal Microbiome After Implantation Failure
Conditions: Implantation Failure; Infertility, Female; Vaginal Flora Imbalance
Intervention: Vivag Plus, Placebo - Cap
Conditions: Implantation Failure; Infertility, Female; Vaginal Flora Imbalance
Intervention: Vivag Plus, Placebo - Cap
September 5, 2019
220
NCT02596243
Unknown status
Unknown status
Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E)
Conditions: Cervical Intraepithelial Neoplasia
Intervention: GX-188E, Placebo
Conditions: Cervical Intraepithelial Neoplasia
Intervention: GX-188E, Placebo
July 11, 2017
221
NCT02683265
Unknown status
Unknown status
A Flexible-Dose Titration Study of Aptensio XR in Children Ages 4 to Under 6 Years Diagnosed With ADHD
Conditions: Attention Deficit Disorder With Hyperactivity
Intervention: Aptensio XR, Placebo
Conditions: Attention Deficit Disorder With Hyperactivity
Intervention: Aptensio XR, Placebo
February 11, 2016
222
NCT03122613
Recruiting
Recruiting
Curcumin for Prevention of Relapse in Patients With Ulcerative Colitis
Conditions: Ulcerative Colitis in Remission
Intervention: Curcumin, Placebo
Conditions: Ulcerative Colitis in Remission
Intervention: Curcumin, Placebo
June 20, 2019
223
NCT02586233
Completed
Completed
Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke
Conditions: Acute Ischemic Stroke; Thrombotic Disease
Intervention: DS-1040b, Placebo
Conditions: Acute Ischemic Stroke; Thrombotic Disease
Intervention: DS-1040b, Placebo
September 6, 2019
224
NCT03183505
Completed
Completed
Comparison of Anyu Peibo With Placebo in Treatment of MDD，Ⅱb
Conditions: Major Depressive Disorder
Intervention: Anyu Peibo, Placebo
Conditions: Major Depressive Disorder
Intervention: Anyu Peibo, Placebo
January 19, 2019
225
NCT02502097
Completed
Completed
A Study of Gefapixant (AF-219/MK-7264) in Subjects With Idiopathic Pulmonary Fibrosis (IPF) With Persistent Cough (MK-7264-016)
Conditions: Idiopathic Pulmonary Fibrosis; Cough
Intervention: Gefapixant First, Then Placebo, Placebo First, Then Gefapixant
Conditions: Idiopathic Pulmonary Fibrosis; Cough
Intervention: Gefapixant First, Then Placebo, Placebo First, Then Gefapixant
May 30, 2017
226
NCT02410343
Terminated
Terminated
Study of TV-1106 in Growth Hormone-Deficient Adults
Conditions: Growth Hormone Deficiency
Intervention: TV-1106, Placebo
Conditions: Growth Hormone Deficiency
Intervention: TV-1106, Placebo
June 8, 2018
227
NCT04083196
Recruiting
Recruiting
A Randomized, Blinded, Placebo-controlled Phase I Clinical Trial Evaluating the Safety and Preliminary Immunogenicity of a 11-valent Recombinant Human Papillomavirus Vaccine (Hanson's Yeast) in Chinese Women Aged 9-45 Years
Conditions: HPV Infection; HPV-Related Cervical Carcinoma
Intervention: 11-valent Recombinant Human Papilloma Virus Vaccine (Hansenula Polymorpha), Placebo
Conditions: HPV Infection; HPV-Related Cervical Carcinoma
Intervention: 11-valent Recombinant Human Papilloma Virus Vaccine (Hansenula Polymorpha), Placebo
September 6, 2019
228
NCT02408354
Unknown status
Unknown status
Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood
Conditions: Alternating Hemiplegia of Childhood
Intervention: Triheptanoin, Placebo
Conditions: Alternating Hemiplegia of Childhood
Intervention: Triheptanoin, Placebo
March 6, 2017
229
NCT03183128
Recruiting
Recruiting
ECOSPOR III - SER-109 Versus Placebo in the Treatment of Adults With Recurrent Clostridium Difficile Infection
Conditions: Clostridium Difficile Infection
Intervention: SER-109, Placebo
Conditions: Clostridium Difficile Infection
Intervention: SER-109, Placebo
May 2, 2019
230
NCT02196324
Completed
Completed
A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)
Conditions: Prurigo Nodularis
Intervention: Serlopitant, Placebo
Conditions: Prurigo Nodularis
Intervention: Serlopitant, Placebo
February 27, 2018
231
NCT00600171
Completed
Completed
Efficacy And Safety Of GW642444M Comparing Placebo In Adolescent And Adult Subjects With Persistent Asthma.
Conditions: Asthma
Intervention: GW642444M, Placebo
Conditions: Asthma
Intervention: GW642444M, Placebo
November 4, 2016
232
NCT03432923
Completed
Completed
A Study to Determine the Efficacy and Safety of a Benzocaine Lozenge for Treatment of Sore Throat.
Conditions: Sore Throat
Intervention: Benzocaine 8 Mg, Placebo
Conditions: Sore Throat
Intervention: Benzocaine 8 Mg, Placebo
October 16, 2018
233
NCT04112147
Recruiting
Recruiting
A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B
Conditions: Chronic Hepatitis B
Intervention: Antroquinonol Capsule 100mg, Antroquinonol Capsule 200mg, Placebo Oral Capsule
Conditions: Chronic Hepatitis B
Intervention: Antroquinonol Capsule 100mg, Antroquinonol Capsule 200mg, Placebo Oral Capsule
October 1, 2019
234
NCT03353454
Withdrawn
Withdrawn
A Placebo-controlled Study of Maralixibat (SHP625) in Pediatric Subjects With Progressive Familial Intrahepatic Cholestasis (PFIC)
Conditions: Progressive Familial Intrahepatic Cholestasis (PFIC)
Intervention: Maralixibat, Placebo
Conditions: Progressive Familial Intrahepatic Cholestasis (PFIC)
Intervention: Maralixibat, Placebo
March 14, 2019
235
NCT02655224
Completed
Completed
A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids
Conditions: Uterine Fibroids
Intervention: Relugolix, Relugolix Placebo
Conditions: Uterine Fibroids
Intervention: Relugolix, Relugolix Placebo
December 25, 2018
236
NCT03943550
Recruiting
Recruiting
Double-Blinded, Placebo-Controlled Phase 1b Study for Safety, PK, Efficacy, PD of RO7049665 in Patients With Ulcerative Colitis (UC)
Conditions: Ulcerative Colitis
Intervention: RO7049665, Placebo
Conditions: Ulcerative Colitis
Intervention: RO7049665, Placebo
May 8, 2019
237
NCT02914262
Completed
Completed
Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD Effects in Male Volunteers
Conditions: IBD
Intervention: AKB-4924, Placebo
Conditions: IBD
Intervention: AKB-4924, Placebo
March 15, 2017
238
NCT03572933
Recruiting
Recruiting
Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder
Conditions: CDKL5 Deficiency Disorder
Intervention: Ganaxolone, Placebo
Conditions: CDKL5 Deficiency Disorder
Intervention: Ganaxolone, Placebo
October 15, 2019
239
NCT03615924
Recruiting
Recruiting
Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease
Intervention: Ticagrelor, Placebo
Conditions: Sickle Cell Disease
Intervention: Ticagrelor, Placebo
August 28, 2019
240
NCT02296411
Completed
Completed
Efficacy of LAMA Added to ICS in Treatment of Asthma
Conditions: Asthma
Intervention: CHF 5259 12.5 Μg, CHF 5259 Placebo
Conditions: Asthma
Intervention: CHF 5259 12.5 Μg, CHF 5259 Placebo
March 28, 2017
241
NCT02472704
Completed
Completed
Lymphocytic Enteritis and Suspected Coeliac Disease: Gluten vs Placebo
Conditions: Celiac Disease; Non-celiac Gluten Sensitivity
Intervention: Gluten Challenge, Placebo Challenge
Conditions: Celiac Disease; Non-celiac Gluten Sensitivity
Intervention: Gluten Challenge, Placebo Challenge
June 15, 2015
242
NCT03542721
Recruiting
Recruiting
Effect of DA-5515 (Circulan® Soft Cap.) in Patients With Chronic Fatigue Symptoms Due to Impaired Blood Circulation
Conditions: Fatigue Symptom
Intervention: DA-5515, Placebo Of DA-5515
Conditions: Fatigue Symptom
Intervention: DA-5515, Placebo Of DA-5515
June 1, 2018
243
NCT02437487
Completed
Completed
SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI)
Conditions: Clostridium Difficile
Intervention: SER-109, Placebo
Conditions: Clostridium Difficile
Intervention: SER-109, Placebo
June 27, 2018
244
NCT02070991
Completed
Completed
Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction
Conditions: Pulmonary Hypertension
Intervention: Macitentan, Placebo
Conditions: Pulmonary Hypertension
Intervention: Macitentan, Placebo
April 24, 2019
245
NCT02051348
Completed
Completed
Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion
Conditions: HELICOBACTER INFECTION
Intervention: Pylopass, Placebo
Conditions: HELICOBACTER INFECTION
Intervention: Pylopass, Placebo
January 14, 2015
246
NCT04020263
Not yet recruiting
Not yet recruiting
Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic Shock
Conditions: Cardiogenic Shock
Intervention: Levosimendan 2.5 MG/ML Injectable Solution, Placebo
Conditions: Cardiogenic Shock
Intervention: Levosimendan 2.5 MG/ML Injectable Solution, Placebo
July 16, 2019
247
NCT02424591
Completed
Completed
A Comparison of Intra-op Ketamine vs Placebo in Patients Having Spinal Fusion
Conditions: Postoperative Pain
Intervention: Ketamine, Placebo
Conditions: Postoperative Pain
Intervention: Ketamine, Placebo
May 19, 2017
248
NCT03876717
Recruiting
Recruiting
Effect of the Sequestrant Colesevelam in Bile Acid Diarrhoea
Conditions: Bile Acid Malabsorption; Chronic Diarrhea
Intervention: Colesevelam Hydrochloride, Placebo Oral Capsule
Conditions: Bile Acid Malabsorption; Chronic Diarrhea
Intervention: Colesevelam Hydrochloride, Placebo Oral Capsule
March 12, 2019
249
NCT03830762
Recruiting
Recruiting
Xanamem™ in Healthy Elderly Subjects
Conditions: Safety; Peripheral Neuropathy; Cortisol; Central Nervous System; Cognitive Function; Healthy Ageing; Small Fibre Neuropathy; Cerebrospinal Fluid; Electrocardiography
Intervention: Xanamem, Matching Placebo
Conditions: Safety; Peripheral Neuropathy; Cortisol; Central Nervous System; Cognitive Function; Healthy Ageing; Small Fibre Neuropathy; Cerebrospinal Fluid; Electrocardiography
Intervention: Xanamem, Matching Placebo
June 24, 2019
250
NCT02334306
Completed
Completed
A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome
Conditions: Primary Sjögren's Syndrome
Intervention: AMG 557/MEDI5872, Placebo
Conditions: Primary Sjögren's Syndrome
Intervention: AMG 557/MEDI5872, Placebo
February 27, 2019
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.