Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Bill and Melinda Gates Foundation [STUDY:SPONSOR-COLLABORATORS] )
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NCTID/Status
Study
Last Changed
1
NCT02196285
Completed
Completed
Study to Evaluate Safety and Imunogenicity of Double Viral Vaccine (MR) for Measles and Rubella
Conditions: Rubella; Measles
Intervention: Double Viral (MR) Vaccine
Conditions: Rubella; Measles
Intervention: Double Viral (MR) Vaccine
June 21, 2016
2
NCT01363765
Completed
Completed
Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil
Conditions: Tuberculosis
Intervention: Xpert MTB/Rif, Smear Microscopy
Conditions: Tuberculosis
Intervention: Xpert MTB/Rif, Smear Microscopy
March 11, 2014
3
NCT04040543
Recruiting
Recruiting
Development of a Marker of Adherence for Tracking Consumption of Nutrient Supplements
Conditions: Adherence, Treatment
Intervention: Lipid-based Nutrient Supplement Containing Adherence Markers, Lipid-based Nutrient Supplement Containing Or Not Containing Adherence Markers, Lipid-based Nutrient Supplement Not Containing Adherence Markers
Conditions: Adherence, Treatment
Intervention: Lipid-based Nutrient Supplement Containing Adherence Markers, Lipid-based Nutrient Supplement Containing Or Not Containing Adherence Markers, Lipid-based Nutrient Supplement Not Containing Adherence Markers
July 30, 2019
4
NCT04029207
Enrolling by invitation
Enrolling by invitation
The ASOS-2 Trial Maternal Mortality Sub-study
Conditions: Maternal Mortality; Cesarean Section; Africa
Intervention: Cesarean Section
Conditions: Maternal Mortality; Cesarean Section; Africa
Intervention: Cesarean Section
July 22, 2019
5
NCT03909737
Not yet recruiting
Not yet recruiting
Oral Azithromycin to Prevent Stillbirths and Infant Mortality in Mali
Conditions: Stillbirths and Infant Mortality
Intervention: Azithromycin To Pregnant Women, Azithromycin To Infants, Placebo To Pregnant Women, Placebo To Infants, No Intervention To Pregnant Women
Conditions: Stillbirths and Infant Mortality
Intervention: Azithromycin To Pregnant Women, Azithromycin To Infants, Placebo To Pregnant Women, Placebo To Infants, No Intervention To Pregnant Women
June 19, 2019
6
NCT03853824
Recruiting
Recruiting
African Surgical OutcomeS-2 (ASOS-2) Trial
Conditions: Surgery; Morality
Intervention: Increased Postoperative Surveillance, Usual Postoperative Care
Conditions: Surgery; Morality
Intervention: Increased Postoperative Surveillance, Usual Postoperative Care
August 12, 2019
7
NCT03792022
Not yet recruiting
Not yet recruiting
Timeliness and Completeness of Routine Childhood Vaccinations by 2 Years of Age in Nigeria.
Conditions: Vaccination Failure
Intervention: Adherence To Timely Vaccine Uptake
Conditions: Vaccination Failure
Intervention: Adherence To Timely Vaccine Uptake
December 31, 2018
8
NCT03776500
Recruiting
Recruiting
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of PBTZ169 in Multiple Dosing
Conditions: Tuberculosis, Pulmonary
Intervention: PBTZ169, Placebo
Conditions: Tuberculosis, Pulmonary
Intervention: PBTZ169, Placebo
February 25, 2019
9
NCT03678688
Recruiting
Recruiting
A Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis
Conditions: Pulmonary TB
Intervention: 10 Mg OPC-167832, 30 Mg OPC-167832, 90 Mg OPC-167832, 270 Mg OPC-167832, RHEZ, Low Dose OPC-167832 Plus 200 Mg Delamanid, High Dose OPC-167832 Plus 200 Mg Delamanid, 200 Mg Delamanid Alone
Conditions: Pulmonary TB
Intervention: 10 Mg OPC-167832, 30 Mg OPC-167832, 90 Mg OPC-167832, 270 Mg OPC-167832, RHEZ, Low Dose OPC-167832 Plus 200 Mg Delamanid, High Dose OPC-167832 Plus 200 Mg Delamanid, 200 Mg Delamanid Alone
April 23, 2019
10
NCT03663998
Completed
Completed
Optimising DNA Vaccinations in Healthy Volunteers
Conditions: HIV-1-infection
Intervention: CN54ENV DNA, GENEVAX® IL-12 DNA
Conditions: HIV-1-infection
Intervention: CN54ENV DNA, GENEVAX® IL-12 DNA
September 10, 2018
11
NCT03594279
Active, not recruiting
Active, not recruiting
Community Mobilization and Incentivization for Childhood Diarrhea and Pneumonia
Conditions: Childhood Diarrhea; Childhood Pneumonia; Community Mobilisation; Sanitation and Hygiene; Community Incentives
Intervention: Community Mobilization, Community Mobilization And Community Incentive
Conditions: Childhood Diarrhea; Childhood Pneumonia; Community Mobilisation; Sanitation and Hygiene; Community Incentives
Intervention: Community Mobilization, Community Mobilization And Community Incentive
July 24, 2018
12
NCT03588377
Active, not recruiting
Active, not recruiting
Impact of Pulse Oximetry on Hospital Referral Acceptance in Children Under 5 With Severe Pneumonia
Conditions: Severe Pneumonia; Hypoxemia
Intervention: Pulse Oximetry
Conditions: Severe Pneumonia; Hypoxemia
Intervention: Pulse Oximetry
July 4, 2018
13
NCT03566160
Enrolling by invitation
Enrolling by invitation
Pilot Study for Evaluation of Cryobiopsy and Correlation With Standard Forceps Biopsy
Conditions: Environmental Enteric Dysfunction (EED)
Intervention: Cryobiopsy Probe, Administered To Study Participants
Conditions: Environmental Enteric Dysfunction (EED)
Intervention: Cryobiopsy Probe, Administered To Study Participants
November 26, 2018
14
NCT03561012
Completed
Completed
Team-Based Goals and Incentives for Community-Based Health Workers to Promote Maternal and Child Health in Bihar, India
Conditions: Healthy
Intervention: Team-Based Goals And Incentives, Control Condition
Conditions: Healthy
Intervention: Team-Based Goals And Incentives, Control Condition
June 6, 2018
15
NCT03554798
Recruiting
Recruiting
A Study to Evaluate the Safety and Immunogenicity of Novel Oral Polio Vaccine
Conditions: Poliomyelitis
Intervention: MOPV (monovalent Oral Polio Vaccine)
Conditions: Poliomyelitis
Intervention: MOPV (monovalent Oral Polio Vaccine)
December 20, 2018
16
NCT03545204
Not yet recruiting
Not yet recruiting
Implementation Research of Kangaroo Mother Care in Rural Pakistan.
Conditions: Low-Birth-Weight Infant
Intervention: Kangaroo Mother Care, Routine Standard Care
Conditions: Low-Birth-Weight Infant
Intervention: Kangaroo Mother Care, Routine Standard Care
January 19, 2019
17
NCT03423030
Completed
Completed
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation
Conditions: Tuberculosis; Tuberculosis, Pulmonary
Intervention: PBTZ169 Formulation, Placebo, PBTZ169 NCP
Conditions: Tuberculosis; Tuberculosis, Pulmonary
Intervention: PBTZ169 Formulation, Placebo, PBTZ169 NCP
July 12, 2018
18
NCT03406221
Completed
Completed
Use of Mobile Technology by Community-Based Health Workers to Promote Maternal and Child Health in Bihar, India
Conditions: Health; Pregnancy; Infant; Nutrition; Child
Intervention: Information Communication Technology Continuum Of Care Service, Control Condition
Conditions: Health; Pregnancy; Infant; Nutrition; Child
Intervention: Information Communication Technology Continuum Of Care Service, Control Condition
January 19, 2018
19
NCT03363308
Active, not recruiting
Active, not recruiting
Effects of a Health Workforce Capacity Building and Quality Improvement Intervention in Kinshasa
Conditions: Maternal Death; Infant Death; Stillbirth
Intervention: Training For Health Care Workers Supplmented By QI Teams
Conditions: Maternal Death; Infant Death; Stillbirth
Intervention: Training For Health Care Workers Supplmented By QI Teams
February 13, 2019
20
NCT03290924
Completed
Completed
Accelerating Newborn Survival in Ghana Through a Low-dose, High-frequency Health Worker Training Approach
Conditions: Stillbirth; Neonatal Death
Intervention: Low Dose High Frequency Health Worker Training Approach, Active Comparison
Conditions: Stillbirth; Neonatal Death
Intervention: Low Dose High Frequency Health Worker Training Approach, Active Comparison
September 21, 2017
21
NCT03239496
Completed
Completed
A Study to Evaluate Immunogenicity of Intramuscular Full-Dose and Intradermal Fractional Dose of IPV
Conditions: Poliomyelitis
Intervention: IPV, F-IPV
Conditions: Poliomyelitis
Intervention: IPV, F-IPV
December 20, 2018
22
NCT03212677
Recruiting
Recruiting
Safe and Effective Delivery of Supplemental Iron to Healthy Volunteers
Conditions: Iron
Intervention: Ferrous Sulfate, IHAT, Aspiron, Placebo
Conditions: Iron
Intervention: Ferrous Sulfate, IHAT, Aspiron, Placebo
May 7, 2019
23
NCT03180034
Recruiting
Recruiting
Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines
Conditions: Cervical Cancer; Cervical HPV Infection; Anti-HPV Antibody Patterns; Sexually Transmitted Infections
Intervention: Cervarix, Gardasil 9
Conditions: Cervical Cancer; Cervical HPV Infection; Anti-HPV Antibody Patterns; Sexually Transmitted Infections
Intervention: Cervarix, Gardasil 9
April 4, 2019
24
NCT03016949
Withdrawn
Withdrawn
A Study to Evaluate Immunogenicity of Various Schedules of Inactivated Polio Vaccine
Conditions: Poliomyelitis
Intervention: IPV, F-IPV
Conditions: Poliomyelitis
Intervention: IPV, F-IPV
June 26, 2017
25
NCT02944747
Active, not recruiting
Active, not recruiting
Saving Lives With Better Gestational Age Estimation
Conditions: Premature Birth
Intervention: Education & Paper Based Calendar, Education & SMS System, Education & Smart-phone Application
Conditions: Premature Birth
Intervention: Education & Paper Based Calendar, Education & SMS System, Education & Smart-phone Application
December 9, 2018
26
NCT02929992
Recruiting
Recruiting
Delivery Optimization for Antiretroviral Therapy (The DO ART Study)
Conditions: HIV; ART
Intervention: ART Initiation In The Home, Mobile Van Refill And Monitoring, Clinic ART Initiation, Clinic ART Refill And Monitoring
Conditions: HIV; ART
Intervention: ART Initiation In The Home, Mobile Van Refill And Monitoring, Clinic ART Initiation, Clinic ART Refill And Monitoring
October 9, 2018
27
NCT02908503
Completed
Completed
Vaginal Film Administration and Placement Study: FLAG
Conditions: Healthy Women
Intervention: Placebo Film
Conditions: Healthy Women
Intervention: Placebo Film
July 3, 2018
28
NCT02788786
Completed
Completed
Feasibility and Acceptability of Use of Daily Oral Rinse in Pregnant Women in Rural Nepal
Conditions: Periodontitis; Premature Birth of Newborn
Intervention: Chlorhexidine, Cetylpyridinium Chloride, Salt And Water
Conditions: Periodontitis; Premature Birth of Newborn
Intervention: Chlorhexidine, Cetylpyridinium Chloride, Salt And Water
February 20, 2017
29
NCT02778672
Completed
Completed
Thermal Imaging of the Lung on a Smartphone to Differentiate Bacterial From Non Bacterial Causes of Pneumonia
Conditions: Pneumonia, Bacterial; Infections, Bacterial
Intervention: Thermal Imaging Of Infant's Chest With A Mobile Phone
Conditions: Pneumonia, Bacterial; Infections, Bacterial
Intervention: Thermal Imaging Of Infant's Chest With A Mobile Phone
September 5, 2017
30
NCT02776748
Completed
Completed
PrEP in Breastfeeding Study
Conditions: HIV Pre-exposure Prophylaxis During Breastfeeding
Intervention: FTC/TDF PrEP
Conditions: HIV Pre-exposure Prophylaxis During Breastfeeding
Intervention: FTC/TDF PrEP
May 17, 2016
31
NCT02726230
Completed
Completed
March 27, 2016
32
NCT02670772
Completed
Completed
Dose Optimisation of Stavudine for the Treatment of HIV Infection
Conditions: Acquired Immune Deficiency Syndrome; Human Immunodeficiency Virus
Intervention: Stavudine, Tenofovir Disoproxil Fumarate
Conditions: Acquired Immune Deficiency Syndrome; Human Immunodeficiency Virus
Intervention: Stavudine, Tenofovir Disoproxil Fumarate
January 28, 2016
33
NCT02624947
Completed
Completed
A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization
Conditions: Respiratory Syncytial Virus Infections
Intervention: RSV F Vaccine With Adjuvant, Formulation Buffer
Conditions: Respiratory Syncytial Virus Infections
Intervention: RSV F Vaccine With Adjuvant, Formulation Buffer
August 20, 2019
34
NCT02582255
Completed
Completed
A Study to Evaluate the Safety and Immunogenicity of Monovalent OPV2 in Children Aged 1 to 5 Years in Lithuania
Conditions: Poliomyelitis
Intervention: Sabin MOPV2
Conditions: Poliomyelitis
Intervention: Sabin MOPV2
May 14, 2018
35
NCT02580201
Completed
Completed
A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age
Conditions: Poliomyelitis
Intervention: Oral Polio Vaccine
Conditions: Poliomyelitis
Intervention: Oral Polio Vaccine
July 10, 2017
36
NCT02534194
Completed
Completed
Gestational Age Assessment Tool
Conditions: Immature Newborn; Premature Birth
Intervention: Image Acquisition
Conditions: Immature Newborn; Premature Birth
Intervention: Image Acquisition
May 11, 2018
37
NCT02521974
Completed
Completed
A Study to Evaluate the Safety and Immunogenicity of Oral Polio Vaccine Type 2 in Infants and Children
Conditions: Adverse Event Following Immunisation
Intervention: SABIN Monovalent OPV2
Conditions: Adverse Event Following Immunisation
Intervention: SABIN Monovalent OPV2
July 10, 2017
38
NCT02448238
Completed
Completed
Pilot Study of Oral Probiotic Bacteria Supplementation to Reduce Chronic Immune Activation in HIV-infected Malian Women
Conditions: HIV
Intervention: VSL#3® Probiotic
Conditions: HIV
Intervention: VSL#3® Probiotic
June 9, 2017
39
NCT02375425
Completed
Completed
Optimization of the ex Vivo Challenge: Reproductive Infections and Contraception
Conditions: HIV
Intervention: No Intervention
Conditions: HIV
Intervention: No Intervention
December 21, 2018
40
NCT02167776
Completed
Completed
From Obstacles to Opportunities for Male Circumcision in Tanzania
Conditions: Male Circumcision
Intervention: Church-based Teaching
Conditions: Male Circumcision
Intervention: Church-based Teaching
January 10, 2017
41
NCT02146248
Completed
Completed
HSG and Tubal Patency Study
Conditions: Tubal Patency
Intervention: Combined Oral Contraceptive, DepoProvera
Conditions: Tubal Patency
Intervention: Combined Oral Contraceptive, DepoProvera
February 17, 2017
42
NCT02134535
Completed
Completed
Optimization of the ex Vivo Challenge
Conditions: Optimization of Laboratory Procedures
Conditions: Optimization of Laboratory Procedures
January 26, 2016
43
NCT02111304
Withdrawn
Withdrawn
September 24, 2014
44
NCT02111135
Completed
Completed
Safety Study of a Single Dose of Monovalent High-dose Inactivated Poliovirus Type 2 Vaccine (m-IPV2 HD) in Infants Early in Life
Conditions: Polio
Intervention: B-OPV, M-OPV2, M-IPV HD, T-IPV
Conditions: Polio
Intervention: B-OPV, M-OPV2, M-IPV HD, T-IPV
July 16, 2015
45
NCT02098590
Completed
Completed
Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection
Conditions: Malaria
Intervention: CPS-immunization, Malaria Challenge Infection, P. Falciparum NF135.C10, Malaria Challenge Infection, P. Falciparum NF166.C8, Malaria Challenge Infection, P. Falciparum NF54, Atovaquone/proguanil
Conditions: Malaria
Intervention: CPS-immunization, Malaria Challenge Infection, P. Falciparum NF135.C10, Malaria Challenge Infection, P. Falciparum NF166.C8, Malaria Challenge Infection, P. Falciparum NF54, Atovaquone/proguanil
February 22, 2016
46
NCT02080026
Completed
Completed
Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis
Conditions: Malaria
Intervention: CPS-immunization, Controlled Human Malaria Infection, Chloroquine, Atovaquone/proguanil
Conditions: Malaria
Intervention: CPS-immunization, Controlled Human Malaria Infection, Chloroquine, Atovaquone/proguanil
August 7, 2015
47
NCT02071758
Completed
Completed
Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers
Conditions: Visceral Leishmaniasis
Intervention: LEISH-F3 + SLA-SE, LEISH-F3 + GLA-SE
Conditions: Visceral Leishmaniasis
Intervention: LEISH-F3 + SLA-SE, LEISH-F3 + GLA-SE
February 22, 2016
48
NCT01936454
Completed
Completed
Contraceptive Effectiveness of Sino-implant (II) in China
Conditions: Contraception
Conditions: Contraception
February 16, 2016
49
NCT01841671
Unknown status
Unknown status
Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine
Conditions: Polio
Intervention: IPV, BOPV, MOPV Type 2, Rotarix
Conditions: Polio
Intervention: IPV, BOPV, MOPV Type 2, Rotarix
May 19, 2014
50
NCT01816464
Completed
Completed
Immunogenicity and Safety of Trivalent Influenza Vaccine in Pregnant and Nonpregnant HIV Uninfected Women
Conditions: Influenza
Intervention: Trivalent Influenza Vaccine
Conditions: Influenza
Intervention: Trivalent Influenza Vaccine
January 9, 2015
Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.