Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[SponsorSearch] Jaeb Center for Health Research
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NCTID/Status
Study
Last Changed
1
NCT03866473
Recruiting
Recruiting
A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema
Conditions: Diabetic Macular Edema
Intervention: Retilux, Sham Light Device
Conditions: Diabetic Macular Edema
Intervention: Retilux, Sham Light Device
October 23, 2019
2
NCT03240432
Completed
Completed
Wireless Innovation for Seniors With Diabetes Mellitus
Conditions: Type 1 Diabetes Mellitus
Intervention: Dexcom CGM
Conditions: Type 1 Diabetes Mellitus
Intervention: Dexcom CGM
September 11, 2019
3
NCT04016662
Not yet recruiting
Not yet recruiting
A Trial Evaluating Automated Insulin Delivery Technologies on Hypoglycemia and Quality of Life in Older Adults With Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus
Intervention: Dexcom G6 CGM
Conditions: Type 1 Diabetes Mellitus
Intervention: Dexcom G6 CGM
July 15, 2019
4
NCT04127006
Not yet recruiting
Not yet recruiting
Rate of Progression in EYS Related Retinal Degeneration
Conditions: Retinitis Pigmentosa; Eye Diseases
Conditions: Retinitis Pigmentosa; Eye Diseases
December 11, 2019
5
NCT03998670
Recruiting
Recruiting
Base-in Prism Spectacles for Intermittent Exotropia
Conditions: Exotropia Intermittent
Intervention: Prism Glasses, Non-Prism Glasses
Conditions: Exotropia Intermittent
Intervention: Prism Glasses, Non-Prism Glasses
December 11, 2019
6
NCT03838900
Active, not recruiting
Active, not recruiting
September 6, 2019
7
NCT03677869
Recruiting
Recruiting
Effects of Pneumatic Vitreolysis on Macular Hole
Conditions: Vitreomacular Traction (VMT); and Full-thickness Macular Holes (MH)
Intervention: Intraocular Gas (C3F8)
Conditions: Vitreomacular Traction (VMT); and Full-thickness Macular Holes (MH)
Intervention: Intraocular Gas (C3F8)
October 23, 2019
8
NCT03647267
Recruiting
Recruiting
Effects of Pneumatic Vitreolysis on Vitreomacular Traction
Conditions: Vitreomacular Traction
Intervention: Pneumatic Vitreolysis (C3F8 Injection), Observation
Conditions: Vitreomacular Traction
Intervention: Pneumatic Vitreolysis (C3F8 Injection), Observation
October 23, 2019
9
NCT03501966
Active, not recruiting
Active, not recruiting
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Conditions: Idiopathic Intracranial Hypertension
Intervention: Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
Conditions: Idiopathic Intracranial Hypertension
Intervention: Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
September 23, 2019
10
NCT03345901
Terminated
Terminated
PROMINENT-Eye Ancillary Study (Protocol AD)
Conditions: Diabetic Retinopathy; Diabetic Macular Edema
Intervention: Pemafibrate, Placebo
Conditions: Diabetic Retinopathy; Diabetic Macular Edema
Intervention: Pemafibrate, Placebo
April 3, 2019
11
NCT03342235
Not yet recruiting
Not yet recruiting
Excimer Laser Surgery for Anisometropic Amblyopia
Conditions: Anisometropic Amblyopia; Refractive Errors
Intervention: Photorefractive Keratectomy (PRK), Patching 2 Hours Per Day, VisX STAR S4 IR Excimer Laser System; TECHNOLAS TENEO 317 Excimer Laser
Conditions: Anisometropic Amblyopia; Refractive Errors
Intervention: Photorefractive Keratectomy (PRK), Patching 2 Hours Per Day, VisX STAR S4 IR Excimer Laser System; TECHNOLAS TENEO 317 Excimer Laser
December 2, 2019
12
NCT03334253
Recruiting
Recruiting
Low-Dose Atropine for Treatment of Myopia
Conditions: Myopia
Intervention: Atropine, Placebo Eyedrops
Conditions: Myopia
Intervention: Atropine, Placebo Eyedrops
December 2, 2019
13
NCT03321513
Active, not recruiting
Active, not recruiting
DRCR.Net Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of CI-DME
Conditions: Diabetic Macular Edema
Intervention: Intravitreous Aflibercept, Bevacizumab + Deferred Aflibercept Group
Conditions: Diabetic Macular Edema
Intervention: Intravitreous Aflibercept, Bevacizumab + Deferred Aflibercept Group
December 6, 2019
14
NCT03263494
Active, not recruiting
Active, not recruiting
CGM Intervention in Teens and Young Adults With Type 1 Diabetes (T1D)
Conditions: Type 1 Diabetes Mellitus
Intervention: Continuous Glucose Monitor (CGM)
Conditions: Type 1 Diabetes Mellitus
Intervention: Continuous Glucose Monitor (CGM)
February 22, 2019
15
NCT02634333
Active, not recruiting
Active, not recruiting
Anti-VEGF Treatment for Prevention of PDR/DME
Conditions: Diabetic Retinopathy; Diabetic Macular Edema
Intervention: Prompt Sham, Prompt Aflibercept, Deferred Laser, Deferred Aflibercept
Conditions: Diabetic Retinopathy; Diabetic Macular Edema
Intervention: Prompt Sham, Prompt Aflibercept, Deferred Laser, Deferred Aflibercept
September 20, 2019
16
NCT03146078
Active, not recruiting
Active, not recruiting
Rate of Progression in USH2A-related Retinal Degeneration
Conditions: Usher Syndrome, Type 2A; Retinitis Pigmentosa 39
Conditions: Usher Syndrome, Type 2A; Retinitis Pigmentosa 39
November 21, 2019
17
NCT02045290
Completed
Completed
Insulin Clamp Ancillary Study for Assessment of Insulin Resistance
Conditions: Type 1 Diabetes
Intervention: Metformin, Placebo
Conditions: Type 1 Diabetes
Intervention: Metformin, Placebo
March 10, 2017
18
NCT02983552
Recruiting
Recruiting
Binocular Dig Rush Game Treatment for Amblyopia
Conditions: Amblyopia
Intervention: IPad®, Spectacle Correction
Conditions: Amblyopia
Intervention: IPad®, Spectacle Correction
December 2, 2019
19
NCT02925299
Recruiting
Recruiting
Day and Night Closed-loop in Young People With Type 1 Diabetes
Conditions: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Metabolism Disorders; Endocrine System Diseases; Autoimmune Diseases
Intervention: FlorenceM (US) And FlorenceX (UK), Insulin Pump Therapy
Conditions: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Metabolism Disorders; Endocrine System Diseases; Autoimmune Diseases
Intervention: FlorenceM (US) And FlorenceX (UK), Insulin Pump Therapy
November 12, 2019
20
NCT02858076
Active, not recruiting
Active, not recruiting
Anti-VEGF vs. Prompt Vitrectomy for VH From PDR
Conditions: Proliferative Diabetic Retinopathy; Vitreous Hemorrhage
Intervention: 2-mg Intravitreous Aflibercept Injection, Prompt Vitrectomy Plus Panretinal Photocoagulation
Conditions: Proliferative Diabetic Retinopathy; Vitreous Hemorrhage
Intervention: 2-mg Intravitreous Aflibercept Injection, Prompt Vitrectomy Plus Panretinal Photocoagulation
February 26, 2019
21
NCT02912728
Active, not recruiting
Active, not recruiting
Strategies to Enhance New CGM Use in Early Childhood (SENCE)
Conditions: Type 1 Diabetes Mellitus
Intervention: CGM + Family Behavioral Intervention, Standard CGM
Conditions: Type 1 Diabetes Mellitus
Intervention: CGM + Family Behavioral Intervention, Standard CGM
September 5, 2018
22
NCT01881828
Completed
Completed
Metformin Therapy for Overweight Adolescents With Type 1 Diabetes
Conditions: Type 1 Diabetes
Intervention: Metformin (glucophage), Oral Placebo
Conditions: Type 1 Diabetes
Intervention: Metformin (glucophage), Oral Placebo
December 17, 2018
23
NCT02807350
Active, not recruiting
Active, not recruiting
Trial of Overminus Spectacle Therapy for Intermittent Exotropia
Conditions: Intermittent Exotropia
Intervention: Overminus Treatment, Non-overminus Treatment
Conditions: Intermittent Exotropia
Intervention: Overminus Treatment, Non-overminus Treatment
December 2, 2019
24
NCT02714972
Completed
Completed
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents
Conditions: Type 1 Diabetes; Hypoglycemia; Hyperglycemia; Artificial Pancreas
Intervention: Hyperglycemia Minimization Algorithm
Conditions: Type 1 Diabetes; Hypoglycemia; Hyperglycemia; Artificial Pancreas
Intervention: Hyperglycemia Minimization Algorithm
May 9, 2017
25
NCT02660242
Completed
Completed
The Use of Mini-dose Glucagon to Prevent Exercise-induced Hypoglycemia in Type 1 Diabetes
Conditions: Diabetes Mellitus, Type 1
Intervention: G-Pen Mini™ (glucagon Injection), Glucose Tabs, Basal Insulin Reduction
Conditions: Diabetes Mellitus, Type 1
Intervention: G-Pen Mini™ (glucagon Injection), Glucose Tabs, Basal Insulin Reduction
July 11, 2018
26
NCT01823341
Completed
Completed
Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children
Conditions: Type 1 Diabetes
Intervention: Pump Suspension Algorithm
Conditions: Type 1 Diabetes
Intervention: Pump Suspension Algorithm
August 26, 2016
27
NCT02510040
Completed
Completed
A Prospective Observational Study of Adult Strabismus
Conditions: Convergence Insufficiency; Divergence Insufficiency; Hypertropia
Intervention: Prism, Orthoptic Exercises, Eye Muscle Surgery, Botox Injection
Conditions: Convergence Insufficiency; Divergence Insufficiency; Hypertropia
Intervention: Prism, Orthoptic Exercises, Eye Muscle Surgery, Botox Injection
November 1, 2019
28
NCT02438189
Completed
Completed
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms
Conditions: Type 1 Diabetes
Intervention: Hyperglycemia Minimization Algorithm
Conditions: Type 1 Diabetes
Intervention: Hyperglycemia Minimization Algorithm
August 26, 2016
29
NCT02411578
Completed
Completed
Mini-Dose Glucagon to Treat Non-Severe Hypoglycemia
Conditions: Diabetes Mellitus, Type 1
Intervention: G-Pen Mini™ (glucagon Injection), Glucose Tablets
Conditions: Diabetes Mellitus, Type 1
Intervention: G-Pen Mini™ (glucagon Injection), Glucose Tablets
October 23, 2017
30
NCT02390531
Active, not recruiting
Active, not recruiting
Phase 1 Trial of Bevacizumab Treatment for Severe Retinopathy of Prematurity
Conditions: Retinopathy of Prematurity
Intervention: Bevacizumab
Conditions: Retinopathy of Prematurity
Intervention: Bevacizumab
December 2, 2019
31
NCT02258373
Completed
Completed
A Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults With Type 1 Diabetes
Conditions: Type 1 Diabetes
Intervention: CGM+BGM, CGM Only
Conditions: Type 1 Diabetes
Intervention: CGM+BGM, CGM Only
August 8, 2018
32
NCT02223650
Completed
Completed
A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia
Conditions: Intermittent Exotropia
Intervention: Overminus Treatment, Non-overminus Treatment
Conditions: Intermittent Exotropia
Intervention: Overminus Treatment, Non-overminus Treatment
April 11, 2017
33
NCT02200211
Completed
Completed
Study of Binocular Computer Activities for Treatment of Amblyopia
Conditions: Amblyopia
Intervention: IPad®, Patching 2 Hours Per Day, 7 Days Per Week
Conditions: Amblyopia
Intervention: IPad®, Patching 2 Hours Per Day, 7 Days Per Week
February 25, 2019
34
NCT02137512
Completed
Completed
Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use
Conditions: Type 1 Diabetes
Intervention: Closed-Loop Control System, Sensor-Augmented Pump (SAP)
Conditions: Type 1 Diabetes
Intervention: Closed-Loop Control System, Sensor-Augmented Pump (SAP)
October 26, 2018
35
NCT01909791
Completed
Completed
Treatment for CI-DME in Eyes With Very Good VA Study
Conditions: Diabetic Macular Edema
Intervention: Prompt Laser, Prompt Aflibercept, Deferred Laser, Deferred Aflibercept
Conditions: Diabetic Macular Edema
Intervention: Prompt Laser, Prompt Aflibercept, Deferred Laser, Deferred Aflibercept
March 6, 2019
36
NCT01945866
Completed
Completed
Phase II Combination Steroid and Anti-VEGF for Persistent DME
Conditions: Diabetic Macular Edema
Intervention: Intravitreal Ranibizumab 0.3 Mg, Dexamethasone Intravitreal Implant, Sham Injection
Conditions: Diabetic Macular Edema
Intervention: Intravitreal Ranibizumab 0.3 Mg, Dexamethasone Intravitreal Implant, Sham Injection
September 24, 2018
37
NCT01736930
Completed
Completed
An Outpatient Pump Shutoff Pilot Feasibility and Safety Study
Conditions: Type 1 Diabetes
Intervention: Pump Suspension
Conditions: Type 1 Diabetes
Intervention: Pump Suspension
August 26, 2016
38
NCT01627249
Completed
Completed
Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema
Conditions: Diabetic Macular Edema
Intervention: 2.0 Mg Intravitreal Aflibercept, 1.25 Mg Intravitreal Bevacizumab, 0.3 Mg Intravitreal Ranibizumab
Conditions: Diabetic Macular Edema
Intervention: 2.0 Mg Intravitreal Aflibercept, 1.25 Mg Intravitreal Bevacizumab, 0.3 Mg Intravitreal Ranibizumab
September 20, 2019
39
NCT01591681
Completed
Completed
Outpatient Pump Shutoff Pilot Feasibility and Efficacy Study
Conditions: Type 1 Diabetes
Intervention: Pump Suspension
Conditions: Type 1 Diabetes
Intervention: Pump Suspension
August 26, 2016
40
NCT01515943
Completed
Completed
Convergence Insufficiency Treatment Study (CITS)
Conditions: Convergence Insufficiency
Intervention: Active Home-based Computer Vergence/accommodative Therapy, Near Target Push-ups, Placebo Home-based Computer Vergence/accommodative Therapy, Placebo Yoked Prism Flippers
Conditions: Convergence Insufficiency
Intervention: Active Home-based Computer Vergence/accommodative Therapy, Near Target Push-ups, Placebo Home-based Computer Vergence/accommodative Therapy, Placebo Yoked Prism Flippers
April 11, 2017
41
NCT01515475
Completed
Completed
Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation
Conditions: Hyperopia
Intervention: Glasses
Conditions: Hyperopia
Intervention: Glasses
July 2, 2019
42
NCT01489189
Completed
Completed
Prompt Panretinal Photocoagulation Versus Ranibizumab+Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
Conditions: Proliferative Diabetic Retinopathy
Intervention: Prompt Panretinal Photocoagulation, 0.5-mg Ranibizumab, Deferred Panretinal Photocoagulation
Conditions: Proliferative Diabetic Retinopathy
Intervention: Prompt Panretinal Photocoagulation, 0.5-mg Ranibizumab, Deferred Panretinal Photocoagulation
September 20, 2019
43
NCT01331005
Completed
Completed
NSAID Phase II for Non-central Involved Diabetic Macular Edema (DME)
Conditions: Diabetic Macular Edema
Intervention: Nepafenac 0.1% Drops, Nepafenac Vehicle
Conditions: Diabetic Macular Edema
Intervention: Nepafenac 0.1% Drops, Nepafenac Vehicle
August 21, 2018
44
NCT01323348
Completed
Completed
Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control
Conditions: Diabetes; Diabetic Retinopathy
Intervention: Diabetes Education
Conditions: Diabetes; Diabetic Retinopathy
Intervention: Diabetes Education
August 25, 2016
45
NCT01271023
Completed
Completed
Inpatient Evaluation of an Automated Closed-Loop Control-to-Range System
Conditions: Type 1 Diabetes
Intervention: Control-to-Range Automated Insulin Management System
Conditions: Type 1 Diabetes
Intervention: Control-to-Range Automated Insulin Management System
September 7, 2016
46
NCT01190813
Completed
Completed
Levodopa for the Treatment of Residual Amblyopia
Conditions: Amblyopia
Intervention: Levodopa/Carbidopa, Placebo, Patching
Conditions: Amblyopia
Intervention: Levodopa/Carbidopa, Placebo, Patching
May 3, 2016
47
NCT01032603
Active, not recruiting
Active, not recruiting
Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent Exotropia
Conditions: Exotropia
Intervention: Bilateral Lateral Rectus Recession (BLRc), Unilateral Lateral Rectus Recession With Medial Rectus Resection (R&R)
Conditions: Exotropia
Intervention: Bilateral Lateral Rectus Recession (BLRc), Unilateral Lateral Rectus Recession With Medial Rectus Resection (R&R)
April 15, 2019
48
NCT01032330
Completed
Completed
Observation Versus Occlusion Therapy for Intermittent Exotropia
Conditions: Exotropia
Intervention: Occlusion Treatment
Conditions: Exotropia
Intervention: Occlusion Treatment
April 16, 2019
49
NCT00996437
Completed
Completed
Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (N)
Conditions: Vitreous Hemorrhage; Proliferative Diabetic Retinopathy
Intervention: Ranibizumab, Saline
Conditions: Vitreous Hemorrhage; Proliferative Diabetic Retinopathy
Intervention: Ranibizumab, Saline
August 25, 2016
50
NCT00945100
Completed
Completed
Increasing Patching for Amblyopia in Children 3 to < 8 Years Old
Conditions: Amblyopia
Intervention: Eye Patch, Eye Patch
Conditions: Amblyopia
Intervention: Eye Patch, Eye Patch
July 12, 2016
Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.