Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Hematologic Diseases [STUDY:ALL-FIELDS] )
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#
NCTID/Status
Study
Last Changed
1
NCT03535220
Active, not recruiting
Active, not recruiting
The American Society of Hematology (ASH) Research Registry: A Multicenter Research Registry of Patients With Hematologic Disease
Conditions: Benign and Malignant Hematologic Diseases
Intervention: Protease Inhibitors
Conditions: Benign and Malignant Hematologic Diseases
Intervention: Protease Inhibitors
May 22, 2018
2
NCT00840567
Terminated
Terminated
Skin and Blood Research Samples From Healthy Volunteers and Patients With Hematologic Diseases
Conditions: Anemia, Sickle Cell
Intervention: Skin Biopsy, Blood Draw & Sample
Conditions: Anemia, Sickle Cell
Intervention: Skin Biopsy, Blood Draw & Sample
July 9, 2013
3
NCT03611257
Recruiting
Recruiting
Effect of dRAST on Treatment for Bacteremia in Patients With Hematologic Diseases
Conditions: Hematologic Diseases; Bacteremia Sepsis
Intervention: DRAST, Current Standard Method
Conditions: Hematologic Diseases; Bacteremia Sepsis
Intervention: DRAST, Current Standard Method
September 27, 2018
4
NCT02720679
Recruiting
Recruiting
Investigation of the Genetics of Hematologic Diseases
Conditions: Bone Marrow Failure Syndromes; Erythrocyte Disorder; Leukocyte Disorder; Hemostasis; Blood Coagulation Disorder; Sickle Cell Disease; Dyskeratosis Congenita; Diamond-Blackfan Anemia; Congenital Thrombocytopenia; Severe Congenital Neutropenia; Fanconi Anemia
Conditions: Bone Marrow Failure Syndromes; Erythrocyte Disorder; Leukocyte Disorder; Hemostasis; Blood Coagulation Disorder; Sickle Cell Disease; Dyskeratosis Congenita; Diamond-Blackfan Anemia; Congenital Thrombocytopenia; Severe Congenital Neutropenia; Fanconi Anemia
July 11, 2019
5
NCT02343965
Completed
Completed
The Impact of the Practice of Touch-massage on the Anxiety of Patients With Hematological Disorders Hospitalized in a Protective Environment, a Randomized, Controlled Study
Conditions: Hematologic Diseases
Intervention: Touch-massage
Conditions: Hematologic Diseases
Intervention: Touch-massage
January 20, 2016
6
NCT00365014
Completed
Completed
Progression of Hematopoietic Diseases in Shanghai, China
Conditions: Hematologic Diseases
Conditions: Hematologic Diseases
July 19, 2013
7
NCT00137787
Completed
Completed
Comparing Ciprofloxacin (CPFX) With Cefepime (CFPM) in Febrile Neutropenic Patients With Hematologic Diseases
Conditions: Febrile Neutropenia
Intervention: Ciprofloxacin, Cefepime
Conditions: Febrile Neutropenia
Intervention: Ciprofloxacin, Cefepime
June 25, 2018
8
NCT02442011
Recruiting
Recruiting
Hematology Biobank : Invitro Study of Blood Disorders
Conditions: Hematological Disorders
Conditions: Hematological Disorders
February 26, 2019
9
NCT03093844
Active, not recruiting
Active, not recruiting
Haploidentical CD34+ Selected Cells Combined With Single Unit Umbilical Cord Blood Transplant for Treatment of High-risk Hematologic Disorders
Conditions: Hematologic Disorders
Intervention: Miltenyi CliniMACS® CD34 Reagent System
Conditions: Hematologic Disorders
Intervention: Miltenyi CliniMACS® CD34 Reagent System
April 26, 2019
10
NCT01108159
Completed
Completed
Integrated Whole-Genome Analysis of Hematologic Disorders
Conditions: Hematologic Diseases
Intervention: Blood Draw, Skin Biopsy
Conditions: Hematologic Diseases
Intervention: Blood Draw, Skin Biopsy
May 29, 2018
11
NCT03048344
Completed
Completed
A Phase I, Two-part Study to Determine the Recommended Dose and Evaluate the Safety and Tolerability of a Novel Oral Arsenic Trioxide Formulation (ORH-2014) in Subjects With Advanced Hematological Disorders
Conditions: Advanced Hematological Disorders
Intervention: ORH-2014, ORH-2014
Conditions: Advanced Hematological Disorders
Intervention: ORH-2014, ORH-2014
March 22, 2019
12
NCT01174615
Recruiting
Recruiting
Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth
Conditions: Leukemia
Conditions: Leukemia
May 14, 2019
13
NCT02330718
Recruiting
Recruiting
Prospective and Retrospective Cohort Study to Find New Prognostic Factors and Therapeutic Targets in Patients With Newly Diagnosed or Relapsed Malignant Hematologic Disorder Excluding Acute Leukemia
Conditions: Malignant Hematologic Disorder
Intervention: No Intervention
Conditions: Malignant Hematologic Disorder
Intervention: No Intervention
February 21, 2019
14
NCT00001715
Completed
Completed
Evaluation of Patients With Blood Disorders
Conditions: Hematologic Disease
Conditions: Hematologic Disease
August 14, 2019
15
NCT00223483
Active, not recruiting
Active, not recruiting
Identification and Analysis of Immunomodulatory Molecules in Patients With Hematologic Disorders and Healthy Volunteers
Conditions: Hematologic Diseases; Healthy Volunteers
Intervention: Isolation Of Genomic DNA
Conditions: Hematologic Diseases; Healthy Volunteers
Intervention: Isolation Of Genomic DNA
January 30, 2019
16
NCT03719534
Recruiting
Recruiting
Haplo SCT vs Haplo-cord SCT for Patients With Hematological Disorders
Conditions: Hematopoietic Stem Cell Transplantation; Haplo-identical Donor; Cord Blood; Hematologic Diseases
Intervention: Haplo-SCT, Haplo-cord SCT
Conditions: Hematopoietic Stem Cell Transplantation; Haplo-identical Donor; Cord Blood; Hematologic Diseases
Intervention: Haplo-SCT, Haplo-cord SCT
October 23, 2018
17
NCT00364520
Completed
Completed
Molecular Epidemiology of Benzene-exposed Workers.
Conditions: Hematologic Diseases
Intervention: Shanghai Workers
Conditions: Hematologic Diseases
Intervention: Shanghai Workers
May 19, 2015
18
NCT00582894
Completed
Completed
Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation for Malignant Hematological Diseases
Conditions: Hematological Neoplasms; Hematopoietic Stem Cell Transplantation
Intervention: Busulfex, Fludarabine, ALemtuzumab
Conditions: Hematological Neoplasms; Hematopoietic Stem Cell Transplantation
Intervention: Busulfex, Fludarabine, ALemtuzumab
March 23, 2011
19
NCT03250845
Recruiting
Recruiting
Comparison of Multigam IV (5% vs. 10%) in Patients With an Immunodeficiency Secondary to a Hematological Disorder
Conditions: Hematologic Diseases; Secondary Immune Deficiency
Conditions: Hematologic Diseases; Secondary Immune Deficiency
October 23, 2017
20
NCT00001397
Recruiting
Recruiting
Evaluation, Treatment, and Training for Patients With Blood Disorders
Conditions: Hematologic Diseases
Conditions: Hematologic Diseases
July 30, 2019
21
NCT03870750
Not yet recruiting
Not yet recruiting
Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient; Hematopoietic and Lymphoid Cell Neoplasm; Non-Neoplastic Hematologic and Lymphocytic Disorder
Intervention: Supportive Palliative Care, Clinical Management, Best Practice, Allogeneic Hematopoietic Stem Cell Transplantation, Questionnaire Administration, Quality-of-Life Assessment, Survey Administration
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient; Hematopoietic and Lymphoid Cell Neoplasm; Non-Neoplastic Hematologic and Lymphocytic Disorder
Intervention: Supportive Palliative Care, Clinical Management, Best Practice, Allogeneic Hematopoietic Stem Cell Transplantation, Questionnaire Administration, Quality-of-Life Assessment, Survey Administration
July 16, 2019
22
NCT00695123
Recruiting
Recruiting
Screening for Subjects to Participate in Studies of Blood Disorders
Conditions: Bone Marrow Transplant; Sickle Cell Disease; G-CSF
Conditions: Bone Marrow Transplant; Sickle Cell Disease; G-CSF
August 16, 2019
23
NCT02483325
Completed
Completed
Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases
Conditions: Hematological Diseases
Intervention: Allogeneic Transplant Conditioning
Conditions: Hematological Diseases
Intervention: Allogeneic Transplant Conditioning
January 22, 2019
24
NCT02057185
Active, not recruiting
Active, not recruiting
Occupational Status and Hematological Disease
Conditions: Chronic Myeloid Leukemia; Chronic Lymphocytic Leukemia; Myelodysplastic Syndrome; Chronic Thrombocytopenia; Hodgkin Disease
Intervention: Study Questionnaire, SF-36 Questionnaire
Conditions: Chronic Myeloid Leukemia; Chronic Lymphocytic Leukemia; Myelodysplastic Syndrome; Chronic Thrombocytopenia; Hodgkin Disease
Intervention: Study Questionnaire, SF-36 Questionnaire
November 22, 2018
25
NCT03031106
Recruiting
Recruiting
Multidisciplinary Follow-up of Patients Treated for Malignant Hematological Disease
Conditions: Malignant Hematologic Neoplasm
Conditions: Malignant Hematologic Neoplasm
March 1, 2018
26
NCT03615144
Recruiting
Recruiting
TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors
Conditions: Non-Malignant Hematologic Disorders
Intervention: Melphalan, Thiotepa, Clofarabine, Fludarabine, Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®), CliniMACS Reagents
Conditions: Non-Malignant Hematologic Disorders
Intervention: Melphalan, Thiotepa, Clofarabine, Fludarabine, Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®), CliniMACS Reagents
August 29, 2018
27
NCT03079089
Recruiting
Recruiting
Sequential Conditioning in Haploidentical Transplantation for Hematopoietic Stem Cells in Patients With Relapsed or Refractory Lymphoid Hematological Disorders
Conditions: Refractory or Relapsed Lymphoid Haemopathy
Intervention: Sequential Packaging (SET), Transfusion Graft, Prevention Of GVHD, Care Supports, Lymphocyte Injection Of Prophylactic Donor (PDLI)
Conditions: Refractory or Relapsed Lymphoid Haemopathy
Intervention: Sequential Packaging (SET), Transfusion Graft, Prevention Of GVHD, Care Supports, Lymphocyte Injection Of Prophylactic Donor (PDLI)
January 8, 2019
28
NCT03868527
Recruiting
Recruiting
The ARCAN Database is Used for Retrospective Non-interventional Research Projects. The Database Collects Clinical and Laboratory Data From Patients With Lymphoid Malignancies. The Database Doesn't Require Biological Sample of Patients, it Records Only Information Based on the Patients' Medical File.
Conditions: Hematologic Diseases
Intervention: Data Collection
Conditions: Hematologic Diseases
Intervention: Data Collection
March 8, 2019
29
NCT02461199
Unknown status
Unknown status
Stool Transplantation to Reduce Antibiotic Resistance Transmission
Conditions: Blood Disorders
Intervention: Fecal Microbiota Transplantation
Conditions: Blood Disorders
Intervention: Fecal Microbiota Transplantation
June 2, 2015
30
NCT01974401
Completed
Completed
Effect of Supragingival Irrigators Containing Chlorhexidine on Oral Health in Blood Dyscrasia
Conditions: Severe Neutropenia; Thrombocytopenia; Chemotherapy; Blood Dyscrasia Patients
Intervention: Supragingival Irrigators Containing Chlorhexidine
Conditions: Severe Neutropenia; Thrombocytopenia; Chemotherapy; Blood Dyscrasia Patients
Intervention: Supragingival Irrigators Containing Chlorhexidine
October 26, 2013
31
NCT03426553
Completed
Completed
Clinical Use of Pathogen Reduced Red Blood Cell Suspension
Conditions: Oncologic Disorders; Hematologic Diseases
Intervention: Riboflavin+UV RBC, Irradiated RBC
Conditions: Oncologic Disorders; Hematologic Diseases
Intervention: Riboflavin+UV RBC, Irradiated RBC
December 21, 2018
32
NCT00058825
Terminated
Terminated
Stem Cell Transplant for Hematologic Diseases
Conditions: Hematologic Malignancies
Intervention: Campath 1H, Fludarabine, Stem Cell Transplant, Total Body Irradiation (TBI), FK506 (Tacrolimus) Or Cyclosporine
Conditions: Hematologic Malignancies
Intervention: Campath 1H, Fludarabine, Stem Cell Transplant, Total Body Irradiation (TBI), FK506 (Tacrolimus) Or Cyclosporine
September 20, 2016
33
NCT01178177
Completed
Completed
Radiologic Features of Invasive Pulmonary Aspergillosis
Conditions: Hematologic Disease; Solid Organ Transplantation
Conditions: Hematologic Disease; Solid Organ Transplantation
May 14, 2013
34
NCT01518959
Unknown status
Unknown status
The Effect of 25-OH-Vitamin-D3 Substitution in Patients With Malignant and Immune-hematologic Diseases
Conditions: Chronic Lymphoid Leukemia
Intervention: Cholecalciferol, Oleum Neutralicum
Conditions: Chronic Lymphoid Leukemia
Intervention: Cholecalciferol, Oleum Neutralicum
November 18, 2014
35
NCT00208962
Completed
Completed
Allogeneic Cell Therapy for Adults With Hematologic Malignancies
Conditions: Hematologic Diseases
Intervention: Chemotherapy And Blood Stem Cell Transplantation
Conditions: Hematologic Diseases
Intervention: Chemotherapy And Blood Stem Cell Transplantation
August 11, 2014
36
NCT00341016
Active, not recruiting
Active, not recruiting
Scientific Protocol for the Study of Leukemia and Other Hematologic Diseases Among Clean-up Workers in Ukraine Following the Chernobyl Accident
Conditions: Leukemia
Conditions: Leukemia
March 1, 2019
37
NCT00208949
Terminated
Terminated
A Comparison of Dendritic Cell Content and T-Cell Phenotype Between Granulocyte Colony-Stimulating Factor (G-CSF) or G-CSF + Granulocyte Macrophage (GM)-CSF
Conditions: Hematologic Diseases
Intervention: G-CSF, GM-CSF
Conditions: Hematologic Diseases
Intervention: G-CSF, GM-CSF
August 17, 2012
38
NCT04039100
Not yet recruiting
Not yet recruiting
Family Caregiver Ambassador Support for Family Caregivers of Patients With Hematological Disease
Conditions: Multiple Myeloma; Lymphoma; Bone Marrow Transplantation; Neoplasms; Hematologic Diseases; Leukemia, Myeloid
Intervention: Family Caregiver Ambassador Support
Conditions: Multiple Myeloma; Lymphoma; Bone Marrow Transplantation; Neoplasms; Hematologic Diseases; Leukemia, Myeloid
Intervention: Family Caregiver Ambassador Support
July 31, 2019
39
NCT03735992
Recruiting
Recruiting
Mind-body Medicine for Patients With Malignant Hematological Diseases
Conditions: Hematologic Neoplasms
Intervention: Mind-body Medicine Group Program
Conditions: Hematologic Neoplasms
Intervention: Mind-body Medicine Group Program
February 22, 2019
40
NCT00719888
Recruiting
Recruiting
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease
Conditions: Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia in Remission; Ann Arbor Stage I Burkitt Lymphoma; Ann Arbor Stage I Non-Hodgkin Lymphoma; Ann Arbor Stage II Burkitt Lymphoma; Blasts Under 5 Percent of Bone Marrow Nucleated Cells; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Lymphoblastic Lymphoma; Mantle Cell Lymphoma; Myelodysplastic Syndrome; Myelofibrosis; Pancytopenia; Plasma Cell Myeloma; Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Ann Arbor Stage II Non-Hodgkin Lymphoma; Ann Arbor Stage III Burkitt Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Burkitt Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma; High Risk Acute Myeloid Leukemia; Progressive Disease; Refractory Anemia
Intervention: Cyclophosphamide, Cyclosporine, Double-Unit Umbilical Cord Blood Transplantation, Fludarabine Phosphate, Laboratory Biomarker Analysis, Mycophenolate Mofetil, Total-Body Irradiation, Umbilical Cord Blood Transplantation
Conditions: Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia in Remission; Ann Arbor Stage I Burkitt Lymphoma; Ann Arbor Stage I Non-Hodgkin Lymphoma; Ann Arbor Stage II Burkitt Lymphoma; Blasts Under 5 Percent of Bone Marrow Nucleated Cells; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Lymphoblastic Lymphoma; Mantle Cell Lymphoma; Myelodysplastic Syndrome; Myelofibrosis; Pancytopenia; Plasma Cell Myeloma; Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Ann Arbor Stage II Non-Hodgkin Lymphoma; Ann Arbor Stage III Burkitt Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Burkitt Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma; High Risk Acute Myeloid Leukemia; Progressive Disease; Refractory Anemia
Intervention: Cyclophosphamide, Cyclosporine, Double-Unit Umbilical Cord Blood Transplantation, Fludarabine Phosphate, Laboratory Biomarker Analysis, Mycophenolate Mofetil, Total-Body Irradiation, Umbilical Cord Blood Transplantation
July 8, 2019
41
NCT02494258
Recruiting
Recruiting
A Study to Evaluate Long-term Safety in Subjects With Solid Tumors and Hematological Disorders.
Conditions: Hematologic Neoplasm; Neoplasms
Intervention: CC-486
Conditions: Hematologic Neoplasm; Neoplasms
Intervention: CC-486
November 20, 2018
42
NCT01426295
Completed
Completed
Pharmaco-economic Study of a New Medical Device Performed From the Perspective of the Hospital
Conditions: Hematologic Disease
Intervention: Caphosol, Bicarbonate De Sodium
Conditions: Hematologic Disease
Intervention: Caphosol, Bicarbonate De Sodium
May 2, 2016
43
NCT03408158
Recruiting
Recruiting
HPA Antibodies and the Distribution of Antigen and Antibodies
Conditions: Blood Disease; Platelet Refractoriness; Antibody-mediated Rejection
Intervention: Same Type Infusion Of Main HPA Antigen
Conditions: Blood Disease; Platelet Refractoriness; Antibody-mediated Rejection
Intervention: Same Type Infusion Of Main HPA Antigen
January 6, 2019
44
NCT00071045
Recruiting
Recruiting
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
Conditions: Neoplasms; Hematologic Neoplasms
Conditions: Neoplasms; Hematologic Neoplasms
August 7, 2019
45
NCT02145039
Active, not recruiting
Active, not recruiting
Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases
Conditions: Acute Leukemias; Burkitt's Lymphoma; Chronic Myelogenous Leukemia
Intervention: Fludarabine, Cyclophosphamide, Total Body Irradiation, Haploidentical Stem Cell Transplant
Conditions: Acute Leukemias; Burkitt's Lymphoma; Chronic Myelogenous Leukemia
Intervention: Fludarabine, Cyclophosphamide, Total Body Irradiation, Haploidentical Stem Cell Transplant
September 21, 2018
46
NCT00897260
Completed
Completed
Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders
Conditions: Hematological Malignancy; Bone Marrow Failure Syndrome
Intervention: Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders, Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders, Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders
Conditions: Hematological Malignancy; Bone Marrow Failure Syndrome
Intervention: Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders, Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders, Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders
January 24, 2018
47
NCT01344681
Completed
Completed
Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases
Conditions: Febrile Neutropenia; Hematological Diseases
Intervention: Micafungin Sodium, Itraconazole
Conditions: Febrile Neutropenia; Hematological Diseases
Intervention: Micafungin Sodium, Itraconazole
December 4, 2014
48
NCT01556828
Terminated
Terminated
Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing
Conditions: Cutaneous Lymphoma; Other Skin Disorders; Mycosis Fungoides; Cutaneous T-cell Lymphoma
Conditions: Cutaneous Lymphoma; Other Skin Disorders; Mycosis Fungoides; Cutaneous T-cell Lymphoma
June 22, 2016
49
NCT03207854
Recruiting
Recruiting
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
Conditions: Healthy Subject; Hematologic and Lymphocytic Disorder; Hematopoietic and Lymphoid Cell Neoplasm; Immune System Disorder; Malignant Neoplasm
Intervention: Biospecimen Collection, Laboratory Biomarker Analysis, Questionnaire Administration
Conditions: Healthy Subject; Hematologic and Lymphocytic Disorder; Hematopoietic and Lymphoid Cell Neoplasm; Immune System Disorder; Malignant Neoplasm
Intervention: Biospecimen Collection, Laboratory Biomarker Analysis, Questionnaire Administration
September 18, 2018
50
NCT03086252
Withdrawn
Withdrawn
Patient-Driven Transfusion Thresholds in Hematological Disorders: A Pilot Study
Conditions: Anemia; Aplastic Anemia; Bone Marrow Failure; Hematopoietic and Lymphoid Cell Neoplasm; Leukemia; Myelodysplastic Syndrome
Intervention: Red Blood Cell Transfusions (RBCT)
Conditions: Anemia; Aplastic Anemia; Bone Marrow Failure; Hematopoietic and Lymphoid Cell Neoplasm; Leukemia; Myelodysplastic Syndrome
Intervention: Red Blood Cell Transfusions (RBCT)
July 25, 2018
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Last Updated
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These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
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Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
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Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.