Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Infant Premature Diseases [STUDY:ALL-FIELDS] )
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NCTID/Status
Study
Last Changed
1
NCT01181791
Terminated
Terminated
Effects of Lactobacillus Reuteri in Premature Infants
Conditions: Premature Infant Disease
Intervention: Lactobacillus Reuteri, Placebo
Conditions: Premature Infant Disease
Intervention: Lactobacillus Reuteri, Placebo
August 24, 2017
2
NCT03764813
Completed
Completed
Cord Blood Transfusion In Preterm Neonates (CB-TrIP)
Conditions: Premature Infant Disease; Transfusion Related Complication; Fetal Hemoglobin
Conditions: Premature Infant Disease; Transfusion Related Complication; Fetal Hemoglobin
August 5, 2019
3
NCT03578341
Recruiting
Recruiting
Oral Colostrum and Its Effect on Immune System
Conditions: Immune System Diseases; Premature Infant Disease; Immunoglobulin Deficiency
Intervention: Orally Colostrum
Conditions: Immune System Diseases; Premature Infant Disease; Immunoglobulin Deficiency
Intervention: Orally Colostrum
July 3, 2018
4
NCT03717584
Recruiting
Recruiting
A Cohort Study of the Intestinal Microbiota of Premature Infants
Conditions: Necrotizing Enterocolitis; Bronchopulmonary Dysplasia; Growth Failure
Conditions: Necrotizing Enterocolitis; Bronchopulmonary Dysplasia; Growth Failure
January 18, 2019
5
NCT00710112
Recruiting
Recruiting
Genetic Variants and Susceptibility to Diseases of Prematurity in Very Low Birth-Weight Infants
Conditions: Chronic Lung Disease
Intervention: Gene Variations
Conditions: Chronic Lung Disease
Intervention: Gene Variations
July 8, 2019
6
NCT00551642
Completed
Completed
Safety and Efficacy Study of Nitric Oxide for Inhalation on Chronic Lung Disease in Premature Babies
Conditions: Lung Disease
Intervention: Nitric Oxide For Inhalation, Nitrogen
Conditions: Lung Disease
Intervention: Nitric Oxide For Inhalation, Nitrogen
November 3, 2016
7
NCT00926276
Completed
Completed
The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia
Conditions: Gastroesophageal Reflux Disease; Bronchopulmonary Dysplasia
Intervention: Fundoplication
Conditions: Gastroesophageal Reflux Disease; Bronchopulmonary Dysplasia
Intervention: Fundoplication
December 9, 2014
8
NCT01607216
Completed
Completed
Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies
Conditions: Prematurity; Symptomatic Respiratory Disease; Bronchopulmonary Dysplasia
Conditions: Prematurity; Symptomatic Respiratory Disease; Bronchopulmonary Dysplasia
May 2, 2017
9
NCT01077271
Completed
Completed
Compliance to Synagis (Palivizumab) Under Daily Pediatrician´s Conditions in Premature Infants 33 - 35 wGA
Conditions: Premature Infants
Conditions: Premature Infants
August 20, 2012
10
NCT00883532
Unknown status
Unknown status
Prevention of Chronic Lung Disease (CLD) in Preterm Infants
Conditions: Respiratory Distress Syndrome; Chronic Lung Disease of Prematurity
Intervention: Budesonide, Surfactant And Air (placebo)
Conditions: Respiratory Distress Syndrome; Chronic Lung Disease of Prematurity
Intervention: Budesonide, Surfactant And Air (placebo)
August 7, 2012
11
NCT01721655
Unknown status
Unknown status
Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease
Conditions: Chronic Lung Disease; Bronchopulmonary Dysplasia
Intervention: Spironolactone, Placebo
Conditions: Chronic Lung Disease; Bronchopulmonary Dysplasia
Intervention: Spironolactone, Placebo
November 28, 2016
12
NCT01062828
Terminated
Terminated
Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants
Conditions: Premature Newborn; Necrotizing Enterocolitis
Intervention: Citrulline Samples
Conditions: Premature Newborn; Necrotizing Enterocolitis
Intervention: Citrulline Samples
August 24, 2017
13
NCT03253263
Recruiting
Recruiting
A Clinical Efficacy and Safety Study of SHP607 in Preventing Chronic Lung Disease in Extremely Premature Infants
Conditions: Retinopathy of Prematurity (ROP); Intraventricular Hemorrhage; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
Intervention: SHP607
Conditions: Retinopathy of Prematurity (ROP); Intraventricular Hemorrhage; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
Intervention: SHP607
May 29, 2019
14
NCT02000895
Recruiting
Recruiting
Early Detection of Progressive Kidney Disease in Preterm Infants
Conditions: Kidney Disease; Cardiovascular Disease
Conditions: Kidney Disease; Cardiovascular Disease
June 5, 2019
15
NCT01326611
Completed
Completed
Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants
Conditions: Chronic Lung Disease
Intervention: Clarithromycin, Dextrose
Conditions: Chronic Lung Disease
Intervention: Clarithromycin, Dextrose
March 29, 2011
16
NCT02375854
Recruiting
Recruiting
Outcomes of Neonatal Acute Kidney Injury In Premature Infants
Conditions: Acute Kidney Injury; Chronic Kidney Disease
Intervention: Observation
Conditions: Acute Kidney Injury; Chronic Kidney Disease
Intervention: Observation
April 23, 2019
17
NCT01390753
Completed
Completed
Role of Human Milk Bank in the Protection of Severe Respiratory Disease in Very Low Birth Weight Premature Infants
Conditions: Respiratory Infections
Intervention: Human Donor Milk
Conditions: Respiratory Infections
Intervention: Human Donor Milk
February 13, 2017
18
NCT02164604
Completed
Completed
Lucentis to Treat Retinopathy of Prematurity (ROP) 3 Plus Disease
Conditions: Retinopathy of Prematurity
Intervention: Intravitreal Injection Of 0.03ml Ranibizumab
Conditions: Retinopathy of Prematurity
Intervention: Intravitreal Injection Of 0.03ml Ranibizumab
June 13, 2014
19
NCT00431418
Completed
Completed
The Effect of Sildenafil in Preterm Infants With Evolving Chronic Lung Disease
Conditions: Lung Diseases
Intervention: Sildenafil, Placebo
Conditions: Lung Diseases
Intervention: Sildenafil, Placebo
September 21, 2015
20
NCT02996162
Not yet recruiting
Not yet recruiting
Hypercapnia and Its Association With Long-term Respiratory Morbidities in Premature Infants With Chronic Lung Disease
Conditions: Bronchopulmonary Dysplasia
Intervention: Massimo Root Monitoring System, ISA-Infrared Sidestream Gas Analyzer
Conditions: Bronchopulmonary Dysplasia
Intervention: Massimo Root Monitoring System, ISA-Infrared Sidestream Gas Analyzer
January 23, 2018
21
NCT00006401
Completed
Completed
Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
Conditions: Lung Diseases; Bronchopulmonary Dysplasia
Intervention: INO, Placebo
Conditions: Lung Diseases; Bronchopulmonary Dysplasia
Intervention: INO, Placebo
October 5, 2015
22
NCT01439048
Completed
Completed
Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants
Conditions: Premature Birth
Conditions: Premature Birth
August 27, 2015
23
NCT01460576
Completed
Completed
Improving Prematurity-Related Respiratory Outcomes at Vanderbilt
Conditions: Preterm Birth; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
Conditions: Preterm Birth; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
May 2, 2017
24
NCT03201588
Recruiting
Recruiting
Multi-Center Study to Determine the Role of Fatty Acids in Serum in Preventing Retinopathy of Prematurity (MDM)
Conditions: Ophthalmological Disorder
Intervention: Formulaid
Conditions: Ophthalmological Disorder
Intervention: Formulaid
October 31, 2018
25
NCT03010891
Unknown status
Unknown status
Effects of Bundled Supportive Interventions on Preterm Infants' Stress-Related Outcomes During Invasive Procedures
Conditions: Preterm Infants; Stress
Intervention: The Bundle Of Supportive Interventions, Usual NICU Care
Conditions: Preterm Infants; Stress
Intervention: The Bundle Of Supportive Interventions, Usual NICU Care
January 4, 2017
26
NCT01107535
Completed
Completed
Effectiveness of Synagis (Palivizumab) Immunoprophylaxis in Preterm Infants With High Risk of Severe Respiratory Syncytial Virus (RSV) Infection
Conditions: Respiratory Syncytial Virus Infection
Intervention: Synagis (palivizumab), Monoclonal Antibody For Passive Immunoprophylaxis Against Severe RSV Disease Administered According To Usual Clinical Practice.
Conditions: Respiratory Syncytial Virus Infection
Intervention: Synagis (palivizumab), Monoclonal Antibody For Passive Immunoprophylaxis Against Severe RSV Disease Administered According To Usual Clinical Practice.
October 26, 2012
27
NCT02758834
Completed
Completed
Half-life of Plasma Phytosterols in Preterm Infants on Parenteral Nutrition
Conditions: Liver Diseases
Conditions: Liver Diseases
April 28, 2016
28
NCT01352481
Unknown status
Unknown status
Early Intervention in Very Preterm Children
Conditions: Prematurity; Speech Sound Disorder
Intervention: Early Parent-based Speech Intervention Program
Conditions: Prematurity; Speech Sound Disorder
Intervention: Early Parent-based Speech Intervention Program
May 11, 2011
29
NCT00358891
Unknown status
Unknown status
Follow-Up of VLBW Infants With Chronic Lung Disease: Respiratory Health and Neurodevelopment
Conditions: Premature Birth
Conditions: Premature Birth
August 1, 2006
30
NCT03721640
Recruiting
Recruiting
Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GA
Conditions: Hyaline Membrane Disease; Preterm Infant
Intervention: Electrocardiogram
Conditions: Hyaline Membrane Disease; Preterm Infant
Intervention: Electrocardiogram
March 1, 2019
31
NCT03261609
Active, not recruiting
Active, not recruiting
Risk of Chronic Diseases in Young Adults Born Preterm: Relationship With Inflammation and Oxidative Stress Biomarkers.
Conditions: Prematurity; Extreme
Intervention: Preterm Birth
Conditions: Prematurity; Extreme
Intervention: Preterm Birth
April 10, 2018
32
NCT01435187
Completed
Completed
Prematurity and Respiratory Outcomes Program (PROP)
Conditions: Prematurity; Respiratory Disease
Conditions: Prematurity; Respiratory Disease
November 4, 2016
33
NCT01855347
Unknown status
Unknown status
Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy
Conditions: Infant, Premature, Diseases; Hypoxia; Necrotizing Enterocolitis
Intervention: Near Infrared Spectroscopy
Conditions: Infant, Premature, Diseases; Hypoxia; Necrotizing Enterocolitis
Intervention: Near Infrared Spectroscopy
August 23, 2015
34
NCT02178267
Completed
Completed
Probiotics On Resistant Bacteria Colonization In Preterm Receiving Antibiotics
Conditions: Infant, Premature, Diseases
Intervention: Lactobacillus Reuteri (biogai AB, Sweden)
Conditions: Infant, Premature, Diseases
Intervention: Lactobacillus Reuteri (biogai AB, Sweden)
June 27, 2014
35
NCT01238471
Completed
Completed
Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study
Conditions: Retinopathy of Prematurity
Intervention: Propranolol, Sucrose 5%
Conditions: Retinopathy of Prematurity
Intervention: Propranolol, Sucrose 5%
June 12, 2014
36
NCT01615016
Terminated
Terminated
MISurf Versus InSurE. A Comparison of Minimally Invasive Surfactant Application Techniques in Preterm Infants
Conditions: Hyaline Membrane Disease
Intervention: Minimally Invasive Endotracheal Surfactant Application
Conditions: Hyaline Membrane Disease
Intervention: Minimally Invasive Endotracheal Surfactant Application
August 19, 2017
37
NCT00162747
Completed
Completed
Topical Therapy for Prevention of Infections in Preterm Infants
Conditions: Skin Diseases
Intervention: Aquaphor, Sunflower Seed Oil
Conditions: Skin Diseases
Intervention: Aquaphor, Sunflower Seed Oil
September 11, 2005
38
NCT02043249
Unknown status
Unknown status
Cord Milking and Activity Of The Immune System In Preterm Infants
Conditions: Preterm Delivery
Intervention: CORD MILKING
Conditions: Preterm Delivery
Intervention: CORD MILKING
January 19, 2014
39
NCT03961139
Not yet recruiting
Not yet recruiting
Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effect on Respiratory Morbidity
Conditions: Chronic Lung Disease of Prematurity; Bronchopulmonary Dysplasia
Intervention: Method Of Feeding; Continuous Feeding OR Bolus Feeding
Conditions: Chronic Lung Disease of Prematurity; Bronchopulmonary Dysplasia
Intervention: Method Of Feeding; Continuous Feeding OR Bolus Feeding
May 21, 2019
40
NCT02391389
Completed
Completed
VentFirst Pilot: Ventilating Preterm Infants During Delayed Cord Clamping
Conditions: Infant, Premature, Diseases
Intervention: CPAP Or PPV During DCC
Conditions: Infant, Premature, Diseases
Intervention: CPAP Or PPV During DCC
January 10, 2017
41
NCT00116974
Terminated
Terminated
Periodontal Infection and Prematurity Study
Conditions: Periodontal Diseases; Premature Birth
Intervention: Scaling And Root Planing
Conditions: Periodontal Diseases; Premature Birth
Intervention: Scaling And Root Planing
August 12, 2016
42
NCT02947594
Completed
Completed
Half-life of Plasma Phytosterols in Very Low Birth Weight Preterm Infants With Parenteral Nutrition-associated Cholestasis
Conditions: Liver Disease
Conditions: Liver Disease
January 22, 2018
43
NCT01982357
Suspended
Suspended
Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies
Conditions: Infant, Premature, Diseases
Intervention: Laser Speckle Imaging And Diffuse Optical Spectroscopy
Conditions: Infant, Premature, Diseases
Intervention: Laser Speckle Imaging And Diffuse Optical Spectroscopy
February 21, 2019
44
NCT02683317
Completed
Completed
Enteral Administration of Docosahexaenoic Acid to Prevent Retinopathy of Prematurity
Conditions: Retinopathy of Prematurity
Intervention: Docosahexaenoic Acid, Sunflower Oil
Conditions: Retinopathy of Prematurity
Intervention: Docosahexaenoic Acid, Sunflower Oil
February 1, 2018
45
NCT02333227
Recruiting
Recruiting
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
Conditions: Preterm Birth; Periodontal Disease; Caries, Dental
Intervention: Xylitol Gum
Conditions: Preterm Birth; Periodontal Disease; Caries, Dental
Intervention: Xylitol Gum
July 9, 2018
46
NCT03016767
Completed
Completed
Efficacy of an Oral Stimulation Protocol in Preterm Infants to Shorten the Period Between Enteral and Oral Nutrition
Conditions: Infant, Premature, Diseases
Intervention: Manual Oral Stimulation Protocol
Conditions: Infant, Premature, Diseases
Intervention: Manual Oral Stimulation Protocol
October 26, 2018
47
NCT02310425
Completed
Completed
A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm Infants
Conditions: Infant, Premature, Diseases
Intervention: S. Boulardii, Placebo
Conditions: Infant, Premature, Diseases
Intervention: S. Boulardii, Placebo
December 4, 2014
48
NCT00747851
Recruiting
Recruiting
Necrotizing Enterocolitis (NEC) & Platelet-Activating Factor (PAF)-Stimulated Protein Translation in Premature Infants
Conditions: Necrotizing Enterocolitis (NEC)
Conditions: Necrotizing Enterocolitis (NEC)
December 14, 2018
49
NCT00131248
Completed
Completed
Medical Treatment for Gastroesophageal Reflux Disease (GERD) in Preterm Infants
Conditions: Gastroesophageal Reflux
Intervention: Metaclopramide, Ranitidine, Placebo
Conditions: Gastroesophageal Reflux
Intervention: Metaclopramide, Ranitidine, Placebo
December 12, 2013
50
NCT01569633
Terminated
Terminated
Use of Prokinetics in Early Enteral Feeding in Preterm Infants
Conditions: Feeding Disorder; Nutrition Disorder; Infant,Premature
Intervention: Metclopramide, Erythromycin, Placebo
Conditions: Feeding Disorder; Nutrition Disorder; Infant,Premature
Intervention: Metclopramide, Erythromycin, Placebo
February 13, 2015
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Last Updated
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Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
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These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
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NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
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Examples:
National Cancer Institute
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It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
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It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
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When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
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to quantify side effects, such as number of myocardial infarctions,
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weight loss
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Interventions
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clofibrate
cyclosporine
vitamin e
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cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
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lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
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Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.