Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[BasicSearch] Inflammation
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NCTID/Status
Study
Last Changed
1
NCT03472781
Completed
Completed
Demographics and Clinical Characteristics of Paediatric Intraocular Inflammation in Singapore
Conditions: Intraocular Inflammation in Children
Intervention: No Intervention. A Retrospective Case Review
Conditions: Intraocular Inflammation in Children
Intervention: No Intervention. A Retrospective Case Review
April 3, 2019
2
NCT02865980
Unknown status
Unknown status
Effect of Washing With Clove Extract on Inflammation and Infection Place Logging Shaldon Needle
Conditions: Renal Failure
Intervention: Clove Extract, Betadine
Conditions: Renal Failure
Intervention: Clove Extract, Betadine
August 10, 2016
3
NCT03889158
Recruiting
Recruiting
Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation
Conditions: Aging; Inflammation
Intervention: Typhoid Vaccine/Ascorbic Acid
Conditions: Aging; Inflammation
Intervention: Typhoid Vaccine/Ascorbic Acid
September 24, 2019
4
NCT03262051
Unknown status
Unknown status
Impact of Acute and Chronic Inflammation on Cytochromes P450 Activity Measured With Dried Blood Spot
Conditions: Inflammation
Intervention: CYP Phenotyping
Conditions: Inflammation
Intervention: CYP Phenotyping
September 27, 2017
5
NCT03788824
Recruiting
Recruiting
Evaluation of Inflammation Activity in Ulcerative Colitis by pCLE
Conditions: Inflammation
Conditions: Inflammation
December 23, 2018
6
NCT03524690
Recruiting
Recruiting
Effects of Severe Negative Energy Balance on Inflammation
Conditions: Inflammation
Intervention: Energy Balance, Negative Energy Balance
Conditions: Inflammation
Intervention: Energy Balance, Negative Energy Balance
February 20, 2019
7
NCT02540252
Unknown status
Unknown status
Nutrition and Inflammation Among Patients With Lower Limb Amputation
Conditions: Malnutrition; Inflammation
Intervention: Nutritional Status Among Patients With Lower Limb Amputation
Conditions: Malnutrition; Inflammation
Intervention: Nutritional Status Among Patients With Lower Limb Amputation
January 26, 2017
8
NCT02155816
Completed
Completed
Omega 7 + 3 Combination and Systemic Inflammation
Conditions: Inflammation
Intervention: Omega 7 + 3, Omega 3, Placebo
Conditions: Inflammation
Intervention: Omega 7 + 3, Omega 3, Placebo
July 15, 2015
9
NCT02576067
Completed
Completed
Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study
Conditions: Vascular Inflammation; Atherosclerotic Cardiovascular Disease
Intervention: Low Dose Methotrexate, Placebo
Conditions: Vascular Inflammation; Atherosclerotic Cardiovascular Disease
Intervention: Low Dose Methotrexate, Placebo
April 8, 2019
10
NCT01919983
Completed
Completed
Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden Death
Conditions: Ischemic Cardiomyopathy; Dilated Cardiomyopathy; Inflammation; Sudden Cardiac Death
Conditions: Ischemic Cardiomyopathy; Dilated Cardiomyopathy; Inflammation; Sudden Cardiac Death
December 6, 2017
11
NCT01847638
Completed
Completed
Prolensa (Bromfenac) 0.07% QD vs. Ilevro (Nepafenac) 0.3% QD for Treatment of Ocular Inflammation Post Cataract Surgery
Conditions: Cataract; Retinal Edema; Inflammation
Intervention: Prolensa (bromfenac 0.07%), Ilevro (nepafenac 0.3%)
Conditions: Cataract; Retinal Edema; Inflammation
Intervention: Prolensa (bromfenac 0.07%), Ilevro (nepafenac 0.3%)
October 14, 2018
12
NCT03596723
Terminated
Terminated
KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children
Conditions: Ocular Inflammation
Intervention: KPI-121 1%, Prednisolone Acetate
Conditions: Ocular Inflammation
Intervention: KPI-121 1%, Prednisolone Acetate
January 8, 2019
13
NCT03776682
Recruiting
Recruiting
Myocardial Inflammation in Rheumatoid Arthritis: A Descriptive Study
Conditions: Myocardial Inflammation; Rheumatoid Arthritis; Coronary Artery Disease; Myocardial Strain
Conditions: Myocardial Inflammation; Rheumatoid Arthritis; Coronary Artery Disease; Myocardial Strain
November 5, 2019
14
NCT03532763
Recruiting
Recruiting
Anti-Inflammatory Effect of Tocotrienol Supplementation in Subjects With Moderately Elevated Inflammation
Conditions: Inflammation; Cardiovascular Risk Factor
Intervention: Tocotrienol-rich Fraction, Placebo
Conditions: Inflammation; Cardiovascular Risk Factor
Intervention: Tocotrienol-rich Fraction, Placebo
August 27, 2018
15
NCT03525639
Recruiting
Recruiting
CMR Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance
Conditions: Myocarditis Acute; Myocardial Inflammation
Intervention: Cardiac Magnetic Resonance
Conditions: Myocarditis Acute; Myocardial Inflammation
Intervention: Cardiac Magnetic Resonance
October 4, 2019
16
NCT02077309
Terminated
Terminated
Effect of Linagliptin on Vascular Inflammation in Patients With Type 2 Diabetes Mellitus
Conditions: Diabetes Mellitus Type 2 (T2DM); Vascular Inflammation; Plaque Morphology
Intervention: Linagliptin, Placebo
Conditions: Diabetes Mellitus Type 2 (T2DM); Vascular Inflammation; Plaque Morphology
Intervention: Linagliptin, Placebo
April 10, 2017
17
NCT03886779
Completed
Completed
Study Title: Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (Nepafenac Ophthalmic Suspension) 0.3% QD With Extra (Pulse) Dose on Day of Surgery for Treatment of Ocular Inflammation Associated With Cataract Surgery in a Randomized, Single Masked Clinical Trial
Conditions: Treatment of Ocular Inflammation Associated With Cataract Surgery
Intervention: Bromfenac, Nepafenac
Conditions: Treatment of Ocular Inflammation Associated With Cataract Surgery
Intervention: Bromfenac, Nepafenac
March 28, 2019
18
NCT02079948
Withdrawn
Withdrawn
Inflammation Control For Elders: ICE Study
Conditions: Inflammation; Aging
Intervention: Methotrexate + Folic Acid, Placebo + Folic Acid, Functional MRI Experimental Tasks, Muscle Biopsy
Conditions: Inflammation; Aging
Intervention: Methotrexate + Folic Acid, Placebo + Folic Acid, Functional MRI Experimental Tasks, Muscle Biopsy
October 2, 2015
19
NCT01810003
Completed
Completed
Impact of EPA and DHA Supplementation on Plasma Biomarkers of Inflammation (n3)
Conditions: Cardiovascular Disease, Inflammation
Intervention: High DHA, High EPA, Placebo
Conditions: Cardiovascular Disease, Inflammation
Intervention: High DHA, High EPA, Placebo
February 21, 2018
20
NCT01527604
Completed
Completed
Effects of Avenanthramide-enriched Oats on Inflammation
Conditions: Inflammation
Intervention: Avenanthramide-enriched Oats, Refined Flour Absent Avenanthramides
Conditions: Inflammation
Intervention: Avenanthramide-enriched Oats, Refined Flour Absent Avenanthramides
November 18, 2014
21
NCT03812627
Recruiting
Recruiting
Study of Systemic Impact of Trace Elements Release by Implantable Medical Devices. Identification of Biomarkers of Systemic Inflammation
Conditions: Biomarker; Systemic Inflammation
Intervention: Blood, Urine, Hair, Synovial Fluid And Peri-prosthetic Tissue Collections, Autopsy
Conditions: Biomarker; Systemic Inflammation
Intervention: Blood, Urine, Hair, Synovial Fluid And Peri-prosthetic Tissue Collections, Autopsy
November 22, 2019
22
NCT02151552
Completed
Completed
Assessing NOS Uptake With PET Imaging in Lung Inflammation
Conditions: Lung Inflammation
Intervention: Endotoxin (E. Coli O:113, Reference Endotoxin), [18F](+/-)NOS
Conditions: Lung Inflammation
Intervention: Endotoxin (E. Coli O:113, Reference Endotoxin), [18F](+/-)NOS
July 19, 2018
23
NCT03597542
Completed
Completed
Examining the Relationship Between Acute Meal Intake and Inflammation in Children
Conditions: Obesity; Inflammation
Intervention: Eggs And Carbohydrates
Conditions: Obesity; Inflammation
Intervention: Eggs And Carbohydrates
July 28, 2018
24
NCT00330824
Completed
Completed
Efficacy/Safety of Antibiotic Steroid Combination in Prevention of Post Operative Inflammation in LASIK Surgery
Conditions: Post Lasik Surgery Inflammation
Intervention: Antibiotic/steroid Combination, Moxifloxacin/dexamethasone
Conditions: Post Lasik Surgery Inflammation
Intervention: Antibiotic/steroid Combination, Moxifloxacin/dexamethasone
August 6, 2009
25
NCT02941016
Recruiting
Recruiting
Vascular Inflammation and Cholesterol Lowering Therapy
Conditions: Lipid Lowering, Vascular Inflammation
Intervention: Evolocumab Or Alirocumab
Conditions: Lipid Lowering, Vascular Inflammation
Intervention: Evolocumab Or Alirocumab
October 20, 2016
26
NCT03721822
Recruiting
Recruiting
Pulmonary Inflammation Using FNOS PET in E-cigarette
Conditions: Smoking, Cigarette; Smoking E-cigarette; Healthy Volunteer
Intervention: [18F]NOS
Conditions: Smoking, Cigarette; Smoking E-cigarette; Healthy Volunteer
Intervention: [18F]NOS
September 17, 2019
27
NCT00331084
Completed
Completed
Efficacy/Safety of Antibiotic Steroid Combination in Prevention of Postoperative Inflammation in Cataract Surgery
Conditions: Inflammation Following Cataract Surgery
Intervention: Antibiotic/steroid Combination, Moxifloxacin / Dexamethasone
Conditions: Inflammation Following Cataract Surgery
Intervention: Antibiotic/steroid Combination, Moxifloxacin / Dexamethasone
August 6, 2009
28
NCT03580473
Not yet recruiting
Not yet recruiting
Efficacy and Safety of Saturno IIB Association on the Control of Ocular Inflammation Post-phacoemulsification
Conditions: Ocular Inflammation; Cataract
Intervention: SATURNO II Association, Vigadexa®
Conditions: Ocular Inflammation; Cataract
Intervention: SATURNO II Association, Vigadexa®
May 28, 2019
29
NCT01760902
Completed
Completed
Diet & Activity Community Trial: High-Risk Inflammation
Conditions: Inflammation
Intervention: Diet And Physical Activity
Conditions: Inflammation
Intervention: Diet And Physical Activity
April 16, 2019
30
NCT03312712
Recruiting
Recruiting
Validation of the Analysis Methodology Behind the Use of Quantitative 18F-FDG PET/CT to Assess Lung Inflammation
Conditions: Lung Inflammation; Sarcoidosis
Intervention: PET/CT Scan, LPS Challenge, Saline Challenge, Blood And Urine Sampling
Conditions: Lung Inflammation; Sarcoidosis
Intervention: PET/CT Scan, LPS Challenge, Saline Challenge, Blood And Urine Sampling
January 7, 2020
31
NCT03926117
Recruiting
Recruiting
Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition
Conditions: Chronic Kidney Diseases; Inflammation
Intervention: Ziltivekimab
Conditions: Chronic Kidney Diseases; Inflammation
Intervention: Ziltivekimab
August 2, 2019
32
NCT03158350
Completed
Completed
Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques
Conditions: Gingival Inflammation
Intervention: Instructed Brushing Method
Conditions: Gingival Inflammation
Intervention: Instructed Brushing Method
March 8, 2019
33
NCT03618914
Completed
Completed
Anemia and Inflammation
Conditions: Iron Deficiency Anemia; Inflammation
Intervention: Dultavax And Vaxigrip
Conditions: Iron Deficiency Anemia; Inflammation
Intervention: Dultavax And Vaxigrip
August 20, 2018
34
NCT03906825
Completed
Completed
Effect of CEAG on Inflammation and Endothelial Function
Conditions: Inflammation; Endothelial Dysfunction
Intervention: CEAG, Placebo
Conditions: Inflammation; Endothelial Dysfunction
Intervention: CEAG, Placebo
June 13, 2019
35
NCT01196845
Active, not recruiting
Active, not recruiting
Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome
Conditions: Decrease of Inflammation of Adipose Tissue; Sleep Apnea Syndrome
Intervention: CPAP, CPAP, CPAP, CPAP
Conditions: Decrease of Inflammation of Adipose Tissue; Sleep Apnea Syndrome
Intervention: CPAP, CPAP, CPAP, CPAP
January 16, 2020
36
NCT02006888
Completed
Completed
The Efficacy and Safety of IBI-10090 for the Treatment of Inflammation Associated With Cataract Surgery
Conditions: Inflammation; Cataracts
Intervention: IBI-10090, Placebo
Conditions: Inflammation; Cataracts
Intervention: IBI-10090, Placebo
March 23, 2018
37
NCT02734888
Recruiting
Recruiting
Arterial Inflammation and E-Cigarettes
Conditions: Arterial Inflammation
Intervention: No Drug Or Device, Only A Test. The Test Is Called A PET/CT
Conditions: Arterial Inflammation
Intervention: No Drug Or Device, Only A Test. The Test Is Called A PET/CT
January 22, 2019
38
NCT04126330
Recruiting
Recruiting
Effect of Omega-3 and Probiotic Dietary Supplements on Elevated High Sensitivity C-reactive Protein (Hs-CRP) as a Marker of Low-grade Inflammation
Conditions: Inflammation
Intervention: Probiotic, Omega-3, Vitamin D Supplement, Placebo
Conditions: Inflammation
Intervention: Probiotic, Omega-3, Vitamin D Supplement, Placebo
October 11, 2019
39
NCT03607071
Recruiting
Recruiting
Outcome of Steroid Therapy for Myocardial Inflammation in Scleroderma
Conditions: Myocardial Inflammation
Intervention: Prednisolone And Taper
Conditions: Myocardial Inflammation
Intervention: Prednisolone And Taper
August 13, 2019
40
NCT03322449
Recruiting
Recruiting
APOA2 Gene, Diet, Inflammation and Gut Health
Conditions: Inflammation
Intervention: Animal Diet, Plant Diet
Conditions: Inflammation
Intervention: Animal Diet, Plant Diet
September 9, 2019
41
NCT02074462
Completed
Completed
Effect of Inflammation on Voriconazole Concentration
Conditions: Inflammation; Fungal Infection
Conditions: Inflammation; Fungal Infection
August 13, 2014
42
NCT02305953
Completed
Completed
Cytokines and Vascular Inflammation in Psoriasis
Conditions: Vascular Inflammation; Psoriasis; Coronary Atherosclerosis
Conditions: Vascular Inflammation; Psoriasis; Coronary Atherosclerosis
November 28, 2014
43
NCT02108600
Active, not recruiting
Active, not recruiting
Tocilizumab for Renal Graft Inflammation
Conditions: Late Complication From Kidney Transplant
Intervention: Tocilizumab
Conditions: Late Complication From Kidney Transplant
Intervention: Tocilizumab
October 10, 2018
44
NCT03103490
Recruiting
Recruiting
18F-FSPG PET/MRI or PET/CT Imaging of Cardiac Sarcoidosis or Inflammation
Conditions: Cardiac Sarcoidosis; Myocardial Inflammation
Intervention: 18F-FSPG
Conditions: Cardiac Sarcoidosis; Myocardial Inflammation
Intervention: 18F-FSPG
February 11, 2019
45
NCT02370966
Completed
Completed
Berry Intake - Effects on Systemic and Oral Inflammation
Conditions: Inflammation
Intervention: Berry Powder
Conditions: Inflammation
Intervention: Berry Powder
September 25, 2018
46
NCT00678366
Completed
Completed
Evaluation of Adding Small Amounts of Oxygen to the CO2 Pneumoperitoneum Upon Pain and Inflammation
Conditions: Pain; Inflammation
Intervention: Addition Of 4% Oxygen, Carbon Dioxde
Conditions: Pain; Inflammation
Intervention: Addition Of 4% Oxygen, Carbon Dioxde
October 25, 2011
47
NCT02697695
Completed
Completed
July 29, 2018
48
NCT01216592
Completed
Completed
Airway Inflammation, Symptoms and Lung Function in COPD
Conditions: Chronic Obstructive Pulmonary Disease
Intervention: COPD Treatment
Conditions: Chronic Obstructive Pulmonary Disease
Intervention: COPD Treatment
December 4, 2011
49
NCT03718793
Recruiting
Recruiting
Small Airway Inflammation and Dysfunction in Different Asthma Phenotypes
Conditions: Asthma
Intervention: Peripheral Exhaled Nitric Oxide
Conditions: Asthma
Intervention: Peripheral Exhaled Nitric Oxide
April 11, 2019
50
NCT00114504
Completed
Completed
Detection of Plaque Inflammation by Positron Emission Tomography (PET)-Effects of Simvastatin on Plaque Inflammation
Conditions: Atherosclerosis
Intervention: Simvastatin
Conditions: Atherosclerosis
Intervention: Simvastatin
May 13, 2015
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.