Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[BasicSearch] Undiagnosed
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NCTID/Status
Study
Last Changed
1
NCT01905865
Completed
Completed
The Role of Uncertainty in Coping: The Experience of Parents of Children With Undiagnosed Medical Conditions
Conditions: Undiagnosed Disease
Conditions: Undiagnosed Disease
December 6, 2019
2
NCT02450851
Recruiting
Recruiting
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
Conditions: Genetic Disease
Conditions: Genetic Disease
September 11, 2019
3
NCT03605004
Recruiting
Recruiting
Adult Patients With Undiagnosed Conditions and Their Responses to Clinically Uncertain Results From Exome Sequencing
Conditions: Undiagnosed Disease
Conditions: Undiagnosed Disease
June 8, 2019
4
NCT03678207
Withdrawn
Withdrawn
The Effectiveness of a Preoperative Blood Pressure Screening Program to Identify Undiagnosed Hypertension in Ambulatory Surgery Patients
Conditions: Hypertension; Perioperative Hypertension
Intervention: Anesthesiologist Phone Call
Conditions: Hypertension; Perioperative Hypertension
Intervention: Anesthesiologist Phone Call
October 29, 2019
5
NCT03424772
Recruiting
Recruiting
Whole Genome Sequencing in the Detection of Rare Undiagnosed Genetic Diseases in Children in China
Conditions: Intellectual Disability; Multiple Congenital Anomaly; Rare Diseases
Intervention: Whole Genome Sequencing
Conditions: Intellectual Disability; Multiple Congenital Anomaly; Rare Diseases
Intervention: Whole Genome Sequencing
February 6, 2018
6
NCT00589459
Unknown status
Unknown status
Gender Differences in Prevalence of Undiagnosed Diabetes in ACS
Conditions: Pre-Diabetes; Diabetes
Conditions: Pre-Diabetes; Diabetes
January 8, 2008
7
NCT01716741
Unknown status
Unknown status
Identification of Undiagnosed Gaucher Disease
Conditions: Gaucher Disease
Intervention: Enzyme Analysis
Conditions: Gaucher Disease
Intervention: Enzyme Analysis
October 26, 2012
8
NCT01957085
Completed
Completed
Undiagnosed Hepatitis C Infection in an Urban Hospital
Conditions: Hepatitis C
Intervention: Observation Only, No Intervention
Conditions: Hepatitis C
Intervention: Observation Only, No Intervention
February 26, 2016
9
NCT01716728
Unknown status
Unknown status
Identification of Undiagnosed Lysosomal Acid Lipase Deficiency
Conditions: Lysosomal Acid Lipase Deficiency; Cholesterol Ester Storage Disease
Intervention: Enzyme Analysis
Conditions: Lysosomal Acid Lipase Deficiency; Cholesterol Ester Storage Disease
Intervention: Enzyme Analysis
August 10, 2013
10
NCT01317914
Completed
Completed
Prospective Study of Undiagnosed Celiac Disease
Conditions: Celiac Disease
Intervention: Dietary Instruction
Conditions: Celiac Disease
Intervention: Dietary Instruction
September 28, 2017
11
NCT00998829
Completed
Completed
Study Evaluating The Prevalence Of Undiagnosed Psoriatic Arthritis In Patients With Plaque Psoriasis
Conditions: Arthritis, Psoriatic; Psoriasis
Intervention: Questionnaire
Conditions: Arthritis, Psoriatic; Psoriasis
Intervention: Questionnaire
November 28, 2012
12
NCT01203332
Completed
Completed
Identifying Undiagnosed Asymptomatic HIV Infection in Hispanic/Latino Adolescents and Young Adults
Conditions: HIV
Intervention: Effectiveness Of Different Strategies In HIV Testing And Linkage To Care
Conditions: HIV
Intervention: Effectiveness Of Different Strategies In HIV Testing And Linkage To Care
February 27, 2017
13
NCT03148210
Enrolling by invitation
Enrolling by invitation
Undiagnosed COPD and Asthma Population Study (UCAP)
Conditions: Asthma; COPD
Intervention: Treatment Strategy Using Evidence-based Guidelines For Asthma Or COPD, Smoking Cessation, Participant Education
Conditions: Asthma; COPD
Intervention: Treatment Strategy Using Evidence-based Guidelines For Asthma Or COPD, Smoking Cessation, Participant Education
July 15, 2019
14
NCT00955370
Completed
Completed
The Experience of Uncertainty in Parents of Children With an Undiagnosed Medical Condition
Conditions: Multiple Abnormalities
Conditions: Multiple Abnormalities
June 30, 2017
15
NCT04126486
Not yet recruiting
Not yet recruiting
A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke
Conditions: Atrial Fibrillation; Atrial Flutter
Intervention: AF Detection Intervention
Conditions: Atrial Fibrillation; Atrial Flutter
Intervention: AF Detection Intervention
October 18, 2019
16
NCT01711385
Unknown status
Unknown status
Undiagnosed Diabetes in a Dental Setting
Conditions: Prediabetic State; Type 2 Diabetes Mellitus With Oral Complications; Periodontal Pocket; Tooth Loss
Intervention: Enhanced Intervention
Conditions: Prediabetic State; Type 2 Diabetes Mellitus With Oral Complications; Periodontal Pocket; Tooth Loss
Intervention: Enhanced Intervention
October 18, 2012
17
NCT01380470
Completed
Completed
Prevalence of Undiagnosed Chronic Obstructive Pulmonary Disease Sufferers in the Region of Murcia
Conditions: Chronic Obstructive Pulmonary Disease
Conditions: Chronic Obstructive Pulmonary Disease
December 14, 2017
18
NCT02014714
Unknown status
Unknown status
Single Dose Morphine and Fentanyl Added to Intrathecal Mixture on Orthopedics Patients With Undiagnosed Obstructive Sleep Apnea
Conditions: Obstructive Sleep Apnea of Adult
Intervention: Morphine, Fentanyl
Conditions: Obstructive Sleep Apnea of Adult
Intervention: Morphine, Fentanyl
December 18, 2013
19
NCT02127099
Unknown status
Unknown status
The Incidence of Undiagnosed OSA Compared in Multi-ethic Races of Malaysia & the Associated Postoperative Complications
Conditions: Obstructive Sleep Apnea
Conditions: Obstructive Sleep Apnea
May 6, 2014
20
NCT01648920
Completed
Completed
A Study to Explore the Utility of Fractional Exhaled Nitric Oxide (FeNO) Compared With Methacholine Challenge (MCC) Testing in the Assessment of Patients With Suspected But Undiagnosed Asthma
Conditions: Asthma
Intervention: NIOX MINO® Instrument (09-1100)
Conditions: Asthma
Intervention: NIOX MINO® Instrument (09-1100)
April 8, 2014
21
NCT00316134
Terminated
Terminated
Multiple Biomarkers in Undiagnosed Pleural Effusion
Conditions: Pleural Effusion; Pleural Effusion, Malignant
Intervention: Procedure/Surgery
Conditions: Pleural Effusion; Pleural Effusion, Malignant
Intervention: Procedure/Surgery
November 7, 2011
22
NCT03726827
Completed
Completed
A Self Selected Population Study of Undiagnosed NAFLD and NASH, Using an Echosens FibroScan, in at Risk Populations
Conditions: NAFLD; NASH - Nonalcoholic Steatohepatitis; Cirrhosis, Liver; Fatty Liver
Intervention: Fibroscan Screening
Conditions: NAFLD; NASH - Nonalcoholic Steatohepatitis; Cirrhosis, Liver; Fatty Liver
Intervention: Fibroscan Screening
September 19, 2019
23
NCT04047719
Recruiting
Recruiting
Pneumonia in the ImmunoCompromised - Use of the Karius Test for the Detection of Undiagnosed Pathogens
Conditions: Pneumonia, Bacterial; Pneumonia, Viral; Pneumonia Fungal; Pneumonia Cavitary; Immunocompromised Host
Intervention: Karius Test
Conditions: Pneumonia, Bacterial; Pneumonia, Viral; Pneumonia Fungal; Pneumonia Cavitary; Immunocompromised Host
Intervention: Karius Test
November 11, 2019
24
NCT03979768
Completed
Completed
Risk Assessment of Type 2 Diabetes in Pharmacies
Conditions: Type2 Diabetes
Intervention: Diabetes Risk Assessment Service In Norwegian Community Pharmacies
Conditions: Type2 Diabetes
Intervention: Diabetes Risk Assessment Service In Norwegian Community Pharmacies
October 15, 2019
25
NCT03449602
Recruiting
Recruiting
Minirigid Versus Conventional Rigid Thoracoscopy in Undiagnosed Pleural Effusions
Conditions: Pleural Effusion
Intervention: Mini-thoracoscopy, Conventional Rigid Thoraoscopy
Conditions: Pleural Effusion
Intervention: Mini-thoracoscopy, Conventional Rigid Thoraoscopy
August 31, 2019
26
NCT04070963
Recruiting
Recruiting
Incidence of Poorly Controlled Diabetes in Surgical Population
Conditions: Diabetes Mellitus
Intervention: HbA1C
Conditions: Diabetes Mellitus
Intervention: HbA1C
August 26, 2019
27
NCT03708380
Recruiting
Recruiting
November 21, 2019
28
NCT01420679
Terminated
Terminated
Study of Pralatrexate Versus Observation Following CHOP-based Chemotherapy in Previously Undiagnosed Peripheral T-cell Lymphoma Patients
Conditions: Peripheral T-cell Lymphoma
Intervention: Pralatrexate Injection
Conditions: Peripheral T-cell Lymphoma
Intervention: Pralatrexate Injection
April 30, 2018
29
NCT03581227
Recruiting
Recruiting
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Intervention: CAPTURE Tool
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Intervention: CAPTURE Tool
May 14, 2019
30
NCT02927158
Recruiting
Recruiting
Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community
Conditions: Undiagnosed Disease
Conditions: Undiagnosed Disease
January 8, 2019
31
NCT04056156
Active, not recruiting
Active, not recruiting
Development and Implementation of an HIV-testing Intervention for Primary Care in Belgium
Conditions: HIV Infections
Intervention: HIV-screening Advice, HIV-testing Advice Plus Group-level Training
Conditions: HIV Infections
Intervention: HIV-screening Advice, HIV-testing Advice Plus Group-level Training
August 13, 2019
32
NCT03993847
Not yet recruiting
Not yet recruiting
CLassification of Axial SpondyloarthritiS Inception Cohort
Conditions: Spondyloarthritis
Conditions: Spondyloarthritis
July 23, 2019
33
NCT04005248
Not yet recruiting
Not yet recruiting
Prevalence of HCV in HIV-negative MSM
Conditions: Hepatitis C Virus Infection
Intervention: HCV IgG Test
Conditions: Hepatitis C Virus Infection
Intervention: HCV IgG Test
June 28, 2019
34
NCT02851927
Completed
Completed
Mini Thoracoscopy vs Semirigid Thoracoscopy in Exudative Pleural Effusions
Conditions: Pleural Effusion
Intervention: Mini Thoracoscopy, SemiRigid Thoracoscopy
Conditions: Pleural Effusion
Intervention: Mini Thoracoscopy, SemiRigid Thoracoscopy
December 25, 2018
35
NCT01880177
Completed
Completed
Developing a COPD Case Finding Methodology for Primary Care
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
May 10, 2016
36
NCT01356979
Completed
Completed
Outcome of Patients Undiagnosed Under Medical Thoracoscopy
Conditions: Pleural Diseases
Intervention: Medical Thoracoscopy
Conditions: Pleural Diseases
Intervention: Medical Thoracoscopy
September 24, 2012
37
NCT01934920
Recruiting
Recruiting
Identifying Patients With Unrecognized Treatable Diabetic Macular Edema
Conditions: Diabetic Macular Edema
Conditions: Diabetic Macular Edema
February 6, 2019
38
NCT00786175
Withdrawn
Withdrawn
A Survey to Evaluate the Rate of Abnormal Glucose Tolerance Among Hong Kong Chinese Subjects With Coronary Heart Disease
Conditions: Coronary Heart Disease; Diabetes Mellitus
Conditions: Coronary Heart Disease; Diabetes Mellitus
August 21, 2015
39
NCT03364556
Completed
Completed
Nutritional Intake and Bone Health in Celiac Disease
Conditions: Celiac Disease
Intervention: No Intervention
Conditions: Celiac Disease
Intervention: No Intervention
December 5, 2017
40
NCT02743845
Recruiting
Recruiting
Gene Discovery Core, The Manton Center
Conditions: Undiagnosed Conditions; Rare Disorders; Orphan Diseases
Conditions: Undiagnosed Conditions; Rare Disorders; Orphan Diseases
October 22, 2018
41
NCT01437072
Completed
Completed
Changing Diabetes® World Tour
Conditions: Diabetes; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2
Intervention: No Treatment Given
Conditions: Diabetes; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2
Intervention: No Treatment Given
January 18, 2017
42
NCT03260088
Not yet recruiting
Not yet recruiting
Evaluation Of Pleural Effusion At Assiut University Hospital
Conditions: Pleural Effusion
Intervention: Immunoglobulin G4
Conditions: Pleural Effusion
Intervention: Immunoglobulin G4
August 23, 2017
43
NCT03168945
Active, not recruiting
Active, not recruiting
Xpert Active Case-finding Trial 2: Community-based Active Case-finding for Tuberculosis in South Africa
Conditions: Tuberculosis
Intervention: GeneXpert MTB/RIF, Smear Microscopy
Conditions: Tuberculosis
Intervention: GeneXpert MTB/RIF, Smear Microscopy
September 25, 2019
44
NCT02701504
Active, not recruiting
Active, not recruiting
Undiagnosed Sleep Apnea and Bypass OperaTion
Conditions: Sleep Apnea
Conditions: Sleep Apnea
October 13, 2019
45
NCT03975439
Not yet recruiting
Not yet recruiting
Chronic Kidney Disease and Cardiovascular Disease Risk Assessment
Conditions: Chronic Kidney Diseases; Diabetes Mellitus; Hypertension
Intervention: Hemoglobin A1C, Urinalysis, Whole Blood Creatinine Level
Conditions: Chronic Kidney Diseases; Diabetes Mellitus; Hypertension
Intervention: Hemoglobin A1C, Urinalysis, Whole Blood Creatinine Level
June 4, 2019
46
NCT03311802
Completed
Completed
A Risk Scores for Predicting Prevalence of Diabetes in the LAO Population
Conditions: Undiagnosed Diabetes
Conditions: Undiagnosed Diabetes
October 12, 2017
47
NCT00457080
Completed
Completed
Application of Capnography Monitoring on the General Care Nursing Unit
Conditions: Postoperative Complications
Intervention: Alaris ETCO2 Monitor - Cont. Resp. Rate, & Apnea Events
Conditions: Postoperative Complications
Intervention: Alaris ETCO2 Monitor - Cont. Resp. Rate, & Apnea Events
July 8, 2008
48
NCT02527239
Unknown status
Unknown status
Prevalence of Pompe's Disease in Respiratory Clinics
Conditions: Pompe's Disease
Intervention: Prospective Observational Study
Conditions: Pompe's Disease
Intervention: Prospective Observational Study
August 17, 2015
49
NCT03458962
Enrolling by invitation
Enrolling by invitation
Diagnostic Odyssey: Whole Genome Sequencing (WGS)
Conditions: Genetic Disease; Genetic Syndrome
Intervention: Genetic Enrollees
Conditions: Genetic Disease; Genetic Syndrome
Intervention: Genetic Enrollees
August 12, 2019
50
NCT02814812
Unknown status
Unknown status
Postoperative Comput Tomography as a Predictor of Postoperative Complications After Pancreatic Surgery
Conditions: Pancreatectomy
Intervention: CT Scan
Conditions: Pancreatectomy
Intervention: CT Scan
December 27, 2016
Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.