Clinical Trials on 5q Minus Syndrome

Total 34597 results

National Institutes of Health Clinical Center (CC)

Completed

Leucovorin for the Treatment of 5 q Minus Syndrome

Myelodysplastic Syndrome | 5q Minus Syndrome

United States
University Hospital, Brest

Recruiting

Haploinsufficiency of the RBM22 and SLU7 Genes in Del(5q) Myelodysplastic Syndromes (SMD-RMB22)

Myelodysplastic Syndromes | Myelodysplastic Syndrome With Isolated Del(5Q) | Myelodysplastic Syndrome With Del(5Q)

France
Associazione Qol-one

Recruiting

Efficacy and Safety of Luspatercept for the Treatment of Anemia Due to MDS With del5q, Refractory/Resistant/Intolerant to Prior Treatments, RBC-TD (Phoenix)

Myelodysplastic Syndromes | Anemia | Transfusion-dependent Anemia | Del(5Q)

Italy
Sidney Kimmel Cancer Center at Thomas Jefferson...
Celgene Corporation

Terminated

A Dose Range Finding Study of Lenalidomide in Non-5q Chromosome Deletion in Low and Intermediate Risk Myelodysplastic Syndrome (MDS) Patients

Myelodysplastic Syndrome | MDS | Low to Intermediate-1 MDS | Non-deletion 5q

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDS

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Medtronic BRC

Terminated

Model 20105 Lead Study

Sick Sinus Node Syndrome

South Africa, Netherlands, Canada, Singapore
LivaNova

Completed

Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction Disease

Sinus Node Dysfunction | Brady Tachy Syndrome

United States, France, Belgium, Germany, United Kingdom, Italy, Monaco, Spain
Sidney Kimmel Cancer Center at Thomas Jefferson...

Active, not recruiting

Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
King Saud University

Completed

SILENT SINUS SYNDROME (First Case Report, Saudi Arabia With Recommendation)

SILENT SINUS SYNDROME

Saudi Arabia
Medtronic BRC

Unknown

Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity.

Bradycardia; Sick Sinus Syndrome, AV Block

Germany, Denmark, Netherlands, Austria, Czech Republic, United Kingdom, Sweden, Finland, Italy, Russian Federation, Switzerland
Celgene

Completed

A Non-interventional Study of REVLIMID® (Lenalidomide) Treatment of IPSS Low- or Intermediate-1-risk Myelodysplastic Syndromes Associated With a Deletion 5q or Refractory/Relapsed Mantle Cell Lymphoma in Korea (RevlimidPMS)

Lymphoma, Follicular | Myelodysplastic Syndromes | Lymphoma, Mantle-Cell

Korea, Republic of
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Untreated Adult Acute Myeloid... and other conditions

United States
Abbott Medical Devices

Terminated

Af Ablation In Brady-Tachy Syndrome (Alternative)

Brady-tachy Syndrome

France
University Hospital, Brest

Recruiting

Biocollection in MyeloDysplastic Syndrome (P-MDS) (P-MDS)

Myelodysplastic Syndromes | Chromosome Abnormality | Acute Myeloid Leukemia With Multilineage Dysplasia | Myelodysplastic Syndrome With Ring Sideroblasts | Myelodysplastic Anemia | Myelodysplastic Syndrome With Isolated Del(5Q)

France
Medtronic Cardiac Rhythm and Heart Failure

Completed

Brady MX a Quality Improvement Study

Sinus Node Disfunction

Mexico
Abbott Medical Devices

Completed

Right Ventricular Outflow Tract Study (RVOTCARE)

Sinus-node Dysfunction

China
Vitatron France

Unknown

Arrhythmia Restart Prevention and RatE STabilization in Atrial Fibrillation

Sick Sinus Syndrome | Brady-Tachy Syndrome

France
Klinikum Nürnberg

Unknown

RV Septal Versus Minimized RV Pacing in Sick Sinus Syndrome (VOTE)

Sick Sinus Syndrome

Germany
Medtronic BRC
Vitatron GmbH

Completed

Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial Fibrillation

Sick Sinus Syndrome

Germany
Medtronic BRC
Vitatron GmbH

Unknown

Mode Evaluation in Sick Sinus Syndrome Trial (MODEST)

Sick Sinus Syndrome

Germany
China Medical University Hospital

Unknown

The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome

Sick Sinus Syndrome

Taiwan
The DANPACE Investigator Group

Terminated

The Danish Multicenter Randomised Study on AAI Versus DDD Pacing in Sick Sinus Syndrome

Sick Sinus Syndrome

Denmark
AtriCure, Inc.

Recruiting

Inappropriate Sinus Tachycardia Registry

Postural Tachycardia Syndrome | Inappropriate Sinus Tachycardia

Belgium
LivaNova

Completed

Spontaneous Atrio Ventricular Conduction Preservation (SAVER)

Sinus Node Dysfunction | Bradycardia-Tachycardia Syndrome | Paroxysmal Atrioventricular Block

United Kingdom, France, Germany, Belgium, Italy
Washington University School of Medicine
Dickson, Patricia I., M.D.; Milbrandt, Jeffrey, MD, PhD; Mitra, Rob, PhD; Turner...

Recruiting

Chromosome 9 P Minus Syndrome

Chromosome 9P Deletion Syndrome | 9p Minus Syndrome | Alfi Syndrome | 9P Monosomy | 9P Partial Monosomy Syndrome

United States
Deutsches Herzzentrum Muenchen
Medtronic; Klinikum Bamberg; Krankenhaus Peißenberg

Completed

Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing (ADVANTAGE)

Pacemaker Implantation for Sinus Node Disease

Germany
Shanghai Chest Hospital
The Second Affiliated Hospital of Shandong University of traditional Chinese... and other collaborators

Not yet recruiting

Cardiac Autonomic Nerve Improvement and Pacemaker Therapy in Patients With Sinus Bradycardia

Sinus Bradycardia
Abbott Medical Devices

Completed

To Pace or Not to Pace in Sinus Node Disease (OPTIMIST)

Sinus Node Disease

France
China National Center for Cardiovascular Diseases

Recruiting

Cardiac Denervation Ablation Strategy for Severe Sinus Bradycardia

Sinus Bradycardia

China
Hospital Clinico Universitario de Santiago
Spanish Society of Cardiology; Hospital Universitario Lucus Augusti

Recruiting

Cardioneuroablation Versus Pacemaker Implantation for the Treatment of Symptomatic Sinus Node Dysfunction (DINERVAPACE)

Sick Sinus Syndrome | Sinus Node Dysfunction

Spain
Medtronic Cardiac Rhythm and Heart Failure

Completed

Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady) (IMPROVE Brady)

Sinus Node Dysfunction

Peru, Bangladesh, India, Mexico, Argentina, Russian Federation, Uruguay
Arun Rao
Medtronic

Completed

A Comparison of Rate Response Performance in Pacemaker Patients With an Indication of Sinus Node Dysfunction (CRIPS)

Sinus Node Dysfunction

United States
Military Institute of Medicine, Poland

Unknown

Minimizing Ventricular Pacing

Sinus Node Disease. | First Degree Atrioventricular Block.

Poland
Boston Scientific Corporation

Completed

ImageReady(TM) MR Conditional Pacing System Clinical Study (SAMURAI)

Bradycardia | Sinus Node Dysfunction

United States, Israel, Singapore, Malaysia, Australia, Canada, China
NYU Langone Health

Completed

Effectiveness of Closed Loop Stimulation (CLS) With His Bundle Lead Placement

Sinus Node Dysfunction

United States
The First Affiliated Hospital with Nanjing Medical...
Zhejiang University

Unknown

Atrial Fibrillation With Sinus Node Dysfunction: Intensive Device Follow-up (SAFE PAF-SND)

Atrial Fibrillation | Sinus Node Dysfunction

China
Abbott Medical Devices

Completed

IES-ACap: Influence of Atrial Pulse Width in the Behaviour of ACap™ Confirm Algorithm. (IES-ACap)

Sinus Bradycardia | Sinus Node Disease | Atrio-ventricular Block
Boston Scientific Corporation

Completed

Safety and Performance Study of the INGEVITY Lead

Bradycardia | Sinus Node Dysfunction

United States, Belgium, Germany, Canada, Spain, Sweden, Italy, Malaysia, Denmark, Australia, Austria, United Kingdom, Hong Kong, France, Portugal, Thailand
Biotronik SE & Co. KG

Terminated

Clinical Benefits of the Closed Loop Stimulation in Sinus Node Disease (B3)

Sinus Node Disease

Spain, Hungary, Taiwan, Korea, Republic of, India, Singapore, Italy, China, Malaysia
Aarhus University Hospital
Odense University Hospital; Zealand University Hospital; Rigshospitalet, Denmark and other collaborators

Completed

Reducing Atrial Pacing Rate to Reduce Atrial Fibrillation in Patients With Sick Sinus Syndrome. (DANPACEII)

Atrial Fibrillation | Sinus Node Disease

Denmark
LivaNova

Completed

Evolution of the PR Interval in Patients Implanted With a Pacemaker Using the SafeR Mode (PRECISE)

Atrioventricular Block | Sinus Node Dysfunction

France
Boston Scientific Corporation

Completed

Ingenio Device Algorithm Study (IVORY)

Heart Failure | AV Block | Sinus Node Disease

Denmark, United Kingdom, Spain, Hong Kong, Netherlands, Sweden, Malaysia, Austria, Belgium, France, Germany, Italy
Medtronic Cardiac Rhythm and Heart Failure

Recruiting

Allometric-Pace Study

Sinus Node Dysfunction

China
Stec, Sebastian, MD, PhD, FESC
KCRI

Recruiting

Permanent Pacemaker Implantation or Cardioneuroablation in Sinus Node Dysfunction (SANOK)

Sinus Node Dysfunction

Poland
Maria Vittoria Hospital

Completed

Real Life Automatic Atrial Capture Device Control

Heart Failure | Sinus Bradycardia | Sinus Node Disease | Atrio-ventricular Block
David Haines, MD

Terminated

Left Bundle Area Versus Selective His Bundle Pacing (LEFTBASH)

Bradycardia | Atrioventricular Block | Sinus Node Dysfunction

United States
China National Center for Cardiovascular Diseases
Chinese Academy of Medical Sciences, Fuwai Hospital; Shanghai Jiaotong University... and other collaborators

Unknown

Cardiac Ganglionated Plexus Ablation Before Permanent Pacemaker Implantation in Patients With Sick Sinus Syndrome (GAPS)

Sick Sinus Syndrome | Permanent Pacemaker Implantation | Cardioneuroablation | Ganglionated Plexus

China
Medtronic Bakken Research Center

Completed

PANORAMA Observational Study

Heart Failure | Heart Block | Arrhythmia | Sinus Node Disease

Belgium, Russian Federation, Former Serbia and Montenegro, India, Kuwait, Saudi Arabia
Mayo Clinic
National Cancer Institute (NCI)

Completed

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Myelodysplastic Syndrome With Isolated Del(5q)

United States
Biotronik SE & Co. KG

Completed

Ventricular Pace Suppression Versus Intrinsic Rhythm Support Study (VIPERS)

Sick Sinus Syndrome

Italy

Clinical Trials on 5q Minus Syndrome

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