Clinical Trials on aGVHD

Total 148 results

Chinese PLA General Hospital

Recruiting

Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT

aGVHD | cGVHD

China
Shanghai Jiao Tong University School of Medicine
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Valproic Acid With Methylprenisonlone for the Treatment of Acute GVHD

Peripheral Blood Stem Cell Transplantation | aGVHD

China
Xuzhou Medical University

Recruiting

Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD

cGVHD

China
Equillium
Biocon Limited

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD (EQUATE)

GVHD | GVHD, Acute | aGVHD | Acute-graft-versus-host Disease

United States
Equillium
Biocon Limited

Recruiting

A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)

Graft Versus Host Disease | GVHD | aGVHD | Acute-graft-versus-host Disease | Acute GVHD

United States, Korea, Republic of, Israel, Spain, Germany, Belgium, Italy, Australia, France, Canada, Portugal
Mesoblast, Inc.
Quintiles, Inc.

Completed

A Prospective Study of Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute Graft-Versus-Host Disease (aGVHD)

Grade B aGVHD | Grade C aGVHD | Grade D aGVHD

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Active, not recruiting

A Study of TQ05105 Tablets in Subjects With Glucocorticoid-Refractory Acute Graft-Versus-Host Disease (aGVHD)

Glucocorticoid-Refractory aGVHD

China
Fujian Medical University

Unknown

MSC for Severe aGVHD

Steroid-resistant Severe aGVHD

China
Chinese PLA General Hospital
309th Hospital of Chinese People's Liberation Army; Beijing Naval General Hospital and other collaborators

Completed

Efficacy and Safety Study of ATG for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT

aGVHD

China
Shanghai Jiao Tong University School of Medicine

Unknown

Biomarker Study for Prediction of aGVHD

aGVHD

China
AbGenomics B.V Taiwan Branch

Withdrawn

A Study Evaluating the Efficacy and Safety of Neihulizumab vs "Conventional Treatment" to Treat Sr-aGvHD

Steroid-refractory aGvHD Subsequent to Allogeneic Hematopoietic Cell Transplantation

United States
Kalytera Therapeutics Israel, Ltd.

Active, not recruiting

An Open Label Study of Multiple Doses of Cannabidiol in the Prevention of Acute Graft-Versus-Host Disease (GVHD)

Prevention aGVHD

Australia, Israel
Chinese PLA General Hospital
The Second Hospital of Hebei Medical University; Air Force Military Medical... and other collaborators

Completed

First Line Therapy for High Risk Acute GVHD

Stem Cell Transplant Complications | aGVHD

China
Chinese PLA General Hospital

Completed

Low Dose Ruxolitinib in Combination With Methylprednisolone

Stem Cell Transplant Complications | aGVHD

China
Shanghai Jiao Tong University School of Medicine

Completed

PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT

GVHD, Acute

China
MaaT Pharma

Recruiting

Prospective Interventional Study Exploring the Microbiota Recolonization in SR-GvHD Patients Receiving MaaT013 (ORION)

Steroid Refractory GVHD | Intestinal GVHD

France
Mats Remberger
The Swedish Research Council

Recruiting

Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT (2017-00355)

GVHD, Acute

Sweden, Norway, Denmark
CSL Behring

Terminated

Exploratory Safety Study of ALD518 in Subjects With Steroid-refractory Acute Graft Versus Host Disease (GVHD) (ALD518-010)

Acute GvHD

United States
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Multiparametric Ultrasound Study in Diagnosing GvHD (ECO-STEM)

Intestinal GVHD

Italy
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Humanized Anti-CD25 Antibody for Prophylaxis of aGVHD in Elderly Underwent HID-HSCT

The Effecacy and Safety of Humanized CD25 Antibody in aGVHD Prophylaxis Among Elderly Patients After HID-HSCT
daphne brockington

Unknown

Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD (CARE)

Chronic GVHD After HCT for Cancer or Immune Disease

Canada
Peking University People's Hospital

Not yet recruiting

Efficacy and Safety of Anti-CD25 rhMAb in the Treatment of Steroid-Refractory cGVHD

cGVHD
xuna

Withdrawn

Belimumab for Treatment of cGVHD Following Allo-HCT

cGVHD

China
Nationwide Children's Hospital
Daisy Foundation

Completed

70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 (70% EtOH)

GVHD | Hematopoietic Stem Cell Transplant

United States
Institute of Hematology & Blood Diseases Hospital

Recruiting

Umbilical Cord Mesenchymal Stem Cells as First-line Treatment for Patients With Acute Graft Versus Host Disease

aGVHD

China
University of Salamanca

Recruiting

Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD)

GVHD, Chronic | GVHD,Acute

Spain
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Immune Monitoring After Allogeneic Hematopoietic Stem Cell Transplantation

GVHD | Allogeneic Stem Cell Transplantation

Italy
Duke University

Recruiting

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD

United States
Ciusss de L'Est de l'Île de Montréal
Centre hospitalier de l'Université de Montréal (CHUM)

Not yet recruiting

Improvement of Women's Health After Allogeneic Stem Cell Transplantation (SaFeGreff)

GVHD, Chronic
Shanghai iCELL Biotechnology Co., Ltd, Shanghai...

Not yet recruiting

Safety and Efficacy Study of hAESCs Therapy for aGVHD (aGVHD，hAESCs)

GVHD,Acute
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Acute GVHD

United States
European Society for Blood and Marrow Transplantation
Mallinckrodt

Completed

ECP Combination Study

Steroid Refractory GVHD

Spain, United Kingdom, Sweden, Italy, Israel, France, Denmark, Germany, Poland, Turkey, Romania, Belgium, Greece, Russian Federation
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Ruxolitinib as GVHD Prophylaxis in AA Patients

The Prophylactic Value of Ruxolitinib for aGVHD in HSCT Recipients of AA
Chinese PLA General Hospital

Recruiting

Role of aGVHD Biomarkers on aGVHD Risks (GVHD)

Biomarker | GVHD,Acute

China
Shenzhen Xbiome Biotech Co., Ltd.

Not yet recruiting

Fecal Microbiota Transplant (FMT) Capsule for Improving the Efficacy of GI-aGVHD

GVHD
University of Minnesota

Withdrawn

Allogeneic Skin Grafting

GVHD

United States
IRCCS Policlinico S. Matteo

Completed

Comparison of Two Automated Mononuclear Collection Systems in Patients Undergoing Extracorporeal Photochemotherapy. A Cross-over Equivalence Study. (MNC_CMNC) (CMNC_MNC)

GvHD | Lung Graft Dysfunction

Italy
Rigshospitalet, Denmark
Novo Nordisk A/S

Completed

Systematic Symptom Identification With Disease Specific PROM to Assess Symptoms of Chronic GVHD in Outpatient Care in Patients Post HSCT (SIMPly-CARE)

Hematological Malignancy | GVHD, Chronic

Denmark
Wang Xin

Not yet recruiting

Prophylaxis of Graft-versus-host Disease With Anti-CD25 Antibody in Patients Underwent HSCT

GVHD

China
Hackensack Meridian Health

Terminated

Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell Transplantation

GVHD

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

GVHD | Graft-versus-host-disease | GVHD, Acute

United States
Henry Ford Health System

Completed

Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis

GVHD

United States
St. Petersburg State Pavlov Medical University

Recruiting

Fecal Microbiota Transplantation With Ruxolitinib and Steroids as an Upfront Treatment of Severe Acute Intestinal GVHD (JAK-FMT)

Intestinal GVHD

Russian Federation
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501)

Acute GVHD

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Unknown

Ruxolitinib and Steroid as First Line Therapy for Acute GVHD

Acute GVHD

China
Ossium Health, Inc.

Withdrawn

Mesenchymal Stem Cells (MSCs) for Steroid Refractory Acute GVHD (SR-aGVHD)

GVHD,Acute
Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

SHR0302 and Steroid as First Line Therapy for Chronic GVHD

Chronic GVHD

China
ElsaLys Biotech

Not yet recruiting

Evaluation of EFficacy and SaFEty of Leukotac (Inolimomab) in Pediatric Patients With SR-aGvHD (EiFFEL)

Steroid Refractory GVHD
Central Hospital, Nancy, France
Saint-Louis Hospital, Paris, France

Not yet recruiting

Wharton Jelly Mesenchymal Stromal Cells as GVHD Prophylaxis (HAPLO-GEL)

Graft Failure | GVHD,Acute | Allogeneic Disease

Clinical Trials on aGVHD

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