Clinical Trials on Abnormal Renal Function

Total 14747 results

Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Peking University

Completed

A Pilot Trial of Manlikang in Reducing Salt Intake and Blood Pressure Among Patients With Hypertension

Hypertension | Hypertension With Abnormal Renal Function

China
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Sanofi

Completed

A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment

Hepatic Function Abnormal

Bulgaria, France
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
Sanofi

Terminated

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

Korea, Republic of, Germany
Geisinger Clinic

Completed

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

Abnormal Liver Function

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Sanofi

Completed

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Germany
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Synchrotron Imaging of Human Ovaries Ex Situ

Abnormal Female Reproductive Function

Canada
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
Shanghai 10th People's Hospital

Completed

Compare the Renal Protective Effects of Febuxostat and Benzbromarone

Chronic Kidney Disease | Hyperuricemia | Abnormal Renal Function

China
Shanghai 10th People's Hospital

Unknown

Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients

Chronic Kidney Disease | Hyperuricemia | Abnormal Renal Function

China
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); American Society for Transplantation

Withdrawn

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

High Blood Pressure | Liver Transplant | Renal Function Abnormal

United States
University of Louisville

Completed

Louisville Cooperative Tissue Biorepository (LCTB)

Normal and Abnormal Tissue

United States
Chulalongkorn University

Recruiting

Association Between Renal Reserve Function and Progression of Renal Function to Predict CKD Risk in Thai Elderly

Renal Function Abnormal | Elder

Thailand
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
RWTH Aachen University

Unknown

Impact of Acute Cerebral Diseases on the Autonomous Nervous System: Progression and Correlation to Therapy and Outcome (Pupillometry)

Cerebral Aneurysm | Pupillary Function, Abnormal

Germany
University of Giessen

Completed

Changes in Renal Function and Body Composition in Pulmonary Hypertension

Pulmonary Hypertension | Renal Function Abnormal

Germany
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
Seoul National University Hospital

Unknown

Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems

Overweight | Abnormal Liver Function Tests

Korea, Republic of
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); Office of Dietary Supplements...

Completed

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP)

Second Hand Smoke | Pulmonary Function; Newborn, Abnormal | Infant Wheeze | In-utero Nicotine

United States
Tao Zhang

Unknown

Effects of Dexmedetomidine and Dopamine on Renal Function After Major Surgery

Renal Function

China
Martin Angst

Completed

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

Normal Immune Cell Function

United States
Central Hospital, Nancy, France

Not yet recruiting

Urinary Creatinine Excretion Time in the Neonatal Period (C-Rex)

Renal Function

France
University Hospital, Strasbourg, France

Recruiting

Renal Function Assessment in the Elderly Using Plasma Creatinine Assay and Lean Body Mass Measurement (FREAGE)

Renal Function

France
Englewood Hospital and Medical Center

Withdrawn

Neuropsychological Testing Using Mobile Devices

Inpatients With Normal Neurological Function

United States
Federal University of Minas Gerais

Completed

Intravenous Fluids After Laparoscopic Cholecystectomy

Thirst | Postoperative Nausea | Postoperative Vomiting | Hunger | Fluid Electrolyte Disorders | Renal Function Abnormal
Vitae Pharmaceuticals, Inc.
Brigham and Women's Hospital

Completed

Direct Renin Inhibition and the Kidney

Renal Function

United States
Coordinación de Investigación en Salud, Mexico
Instituto Mexicano del Seguro Social; Universidad de Guanajuato

Completed

Effects of High vs. Standard Protein Intake in Newborn Extreme Premature (experimental)

Malnutrition | Abnormal Renal Function

Mexico
National Institute of Allergy and Infectious Diseases...

Terminated

Inflammatory Responses in Normal Volunteers and Patients With Abnormal Immune Responses

Healthy Volunteers | Abnormal Phagocyte Function

United States
University of Malaya

Not yet recruiting

Development and Validation of Creatinine-Based Estimates of the Glomerular Filtration Rate Equation

Renal Function Disorder

Malaysia
Sun Yat-sen University
Beijing Fresenius Kabi Pharmaceutical Co

Completed

Renal Protective Effects of Restricted Protein Dietary With α-keto Acid in CAPD Patients

Renal Function Disorder

China
Centre for Probe Development and Commercialization
St. Joseph's Healthcare Hamilton; McMaster University

Completed

A Single Centre Open Label Comparison of [I-123]-Ortho-Iodohippuric Acid (OIH) With [Tc-99m]-Mercaptoacetyltriglycine (MAG3) for Assessment of Renal Tubular Function

Renal Function Impairment

Canada
Al-Azhar University
University Hospital Fattouma Bourguiba

Completed

Laparoscopic Assisted Dismembered Pyeloplasty Versus Open Pyeloplasty in (UPJO) With Poorly Function Kidney in Pediatrics

Uretro-pelvic Junction Obstruction | Poorly Function Kidney

Egypt
Hospital de Clinicas de Porto Alegre

Active, not recruiting

The Effect of Water Intake on the State of Hydration and Renal Function in Elderly Patients

Renal Function Disorder

Brazil
VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
NXTech
Kansas State University

Completed

Boost Study 21270 (Cognition)

Cognitive Function Abnormal

United States
Sun Yat-sen University

Withdrawn

Effect of Diuretics on Fluid Status Control and Residual Renal Function in Peritoneal Dialysis Patients

Renal Function Disorder

China
Sun Yat-sen University

Completed

Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients

Renal Function Disorder

China
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants With Normal Renal Function

Renal Impaired | Gilteritinib | Normal Renal Function | Pharmacokinetics of ASP2215

United States, Bulgaria
University Hospital Schleswig-Holstein
University of Kiel

Completed

Polymorphism of the Cytochrome P450-system in Renal Transplants

Function of Renal Transplant

Germany
Klinikum Ludwigshafen
Universitätsmedizin Mannheim

Completed

Inhalative Sedation in ICU With Sevoflurane Via Anaesthetic Conserving Device Compared to Propofol

Renal Function | Hepatic Function | Recovery From Sedation | Cardioprotection | Sevoflurane Consumption
Guy's and St Thomas' NHS Foundation Trust
Astellas Pharma Europe Ltd.

Unknown

RituxiMab INDuction in Renal Transplantation (ReMIND)

Function of Renal Transplant

United Kingdom
Stanford University

Completed

Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant (RTphylline)

Function of Renal Transplant

United States
Nantes University Hospital

Terminated

Protocol Calcineurin Inhibitor (CNI) Weaning

Function of Renal Transplant

France

Clinical Trials on Abnormal Renal Function

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