Clinical Trials on Advanced BRAF-mutant Cancers
Total 2887 results
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Memorial Sloan Kettering Cancer CenterArray BioPharmaCompletedAdvanced BRAF Mutant CancersUnited States
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Cascadian Therapeutics Inc.TerminatedAdvanced BRAF-mutant CancersUnited States
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Providence Health & ServicesAvailableKRAS G12V Mutant Advanced Epithelial Cancers
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Deciphera Pharmaceuticals LLCNot yet recruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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Abramson Cancer Center of the University of PennsylvaniaCompletedAdvanced BRAF Mutant MelanomaUnited States
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Array BioPharmaTerminatedLocally Advanced Metastatic BRAF Mutant MelanomaAustralia, Canada, Netherlands, United States
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingKRAS G12C Mutant Advanced Solid TumorsChina
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Jiangsu HengRui Medicine Co., Ltd.RecruitingAdvanced KRAS G12D Mutant Solid TumorsChina
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AmgenActive, not recruitingKRAS p.G12C Mutant Advanced Solid TumorsUnited States, France, Canada, Spain, Belgium, Korea, Republic of, Austria, Australia, Hungary, Greece, Germany, Japan, Romania, Switzerland, Brazil, Portugal
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Pierre Fabre MedicamentPfizer; Merck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. LtdCompletedBRAF V600E-mutant Metastatic Colorectal CancerFrance, Italy, United States, Spain, United Kingdom, Belgium, Austria, Japan, Netherlands
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PfizerMerck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. Ltd; Pierre Fabre MedicamentCompletedBRAF V600E-mutant Metastatic Colorectal CancerUnited States, Spain, Korea, Republic of, United Kingdom, Australia, Czechia, Taiwan, Belgium, France, Hungary, Canada, Japan, Russian Federation, Netherlands, Israel, Germany, Turkey, Austria, Brazil, Poland, Italy, Argentina, Chile, Denmar... and more
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Fore BiotherapeuticsActive, not recruitingAdvanced Unresectable Solid Tumors | BRAF-mutated TumorsUnited States
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Suzhou Genhouse Bio Co., Ltd.Shanghai East Hospital; Shandong Tumor HospitalRecruitingAdvanced Solid Tumors With MAPK Signal Pathway MutantChina
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University of California, San FranciscoNovartisCompletedBRAF Mutant Metastatic MelanomaUnited States
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BioMed Valley Discoveries, IncTerminatedAdvanced Solid Tumor | MAP2K1 Gene Mutation | BRAF Gene Mutation | MEK Mutation | BRAF Gene Alteration | MEK Alteration | MAP2K1 Gene Alteration | MAP2K2 Gene Mutation | MAP2K2 Gene AlterationUnited States
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PfizerCompletedBRAF or NRAS Mutant Metastatic MelanomaUnited States, Netherlands, Italy, Germany, Switzerland
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Fore BiotherapeuticsRecruitingCancer Harboring BRAF AlterationsUnited States, Germany, Spain, United Kingdom, Korea, Republic of, Italy, France, Sweden, Canada
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University of California, Los AngelesUniversity of California, San Francisco; University of California, IrvineActive, not recruitingAdvanced Cancer | Advance Care Planning | Advance DirectivesUnited States
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MapKure, LLCRecruitingColorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal CancersUnited States
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ABM Therapeutics Shanghai Company LimitedRecruitingAdvanced Solid Tumor | BRAF V600 MutationChina
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UNC Lineberger Comprehensive Cancer CenterGlaxoSmithKlineCompletedUnresectable Melanoma | Stage IV Melanoma | Stage III Melanoma | BRAF Mutant MelanomaUnited States
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West China HospitalRecruitingBRAF V600E-mutated /MSS Metastatic Colorectal Cancer | Vemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal AntibodyChina
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Novartis PharmaceuticalsRecruitingBRAF V600E Mutation-positive Unresectable Advanced or Recurrent Solid TumorJapan
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AIO-Studien-gGmbHUniversitätsklinikum Hamburg-Eppendorf; Merck Serono GmbH, Germany; Pierre Fabre...RecruitingColorectal Cancer | Colon Cancer | BRAF V600 Mutation | BRAF V600E | Localized CancerGermany
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedMetastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | BRAF Gene MutationUnited States
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Day One Biopharmaceuticals, Inc.RecruitingMelanoma | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Thyroid Cancer, Papillary | Pilocytic Astrocytoma | Bladder Urothelial Carcinoma | Non-Small Cell Adenocarcinoma | MEK Mutation | RAS Mutation | Pancreatic Acinar Carcinoma | RAF Mutation | CRAF Gene Amplification | RAF1 Gene Amplification and other conditionsUnited States, Canada, Korea, Republic of, Spain, Australia, Belgium, France
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ABM Therapeutics CorporationActive, not recruitingAdvanced Solid Tumor | BRAF V600 MutationUnited States
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Therapex Co., LtdNot yet recruitingCarcinoma, Non-Small-Cell Lung | EGFR Mutant Advanced Non-Small Cell Lung Cancer
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Bridge Biotherapeutics, Inc.RecruitingEGFR Mutant Advanced Non-Small Cell Lung CancerKorea, Republic of, United States
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J Ints BioRecruitingEGFR Mutant Advanced Non-small Cell Lung CancerKorea, Republic of, United States, Thailand
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Daping Hospital and the Research Institute of Surgery...Not yet recruitingNSCLC | Advanced Cancer | Stage IV NSCLC | BRAF V600E Mutation | Stage IIIB NSCLC
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Memorial Sloan Kettering Cancer CenterAstraZeneca; Genentech, Inc.CompletedNon-small Cell Lung Cancer | EGFR-mutant Lung CancersUnited States
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PfizerCompletedLocally Advanced or Metastatic NRAS Mutant MelanomaUnited States, Australia, Germany, Italy, Netherlands
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University of SydneyAstraZeneca; Australasian Lung Cancer Trials GroupActive, not recruitingEGFR Mutant Advanced Non Small Cell Lung CancerTaiwan, Australia
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Novartis PharmaceuticalsRecruitingContinued Access to Study Treatment(s), Cancers With a Mass, Bulky Tumor, Nodule, Lump, Advanced Cancer, Advanced Solid Tumors, Advanced Solid MalignanciesSpain, United States, Taiwan, Singapore, France
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Kura Oncology, Inc.CompletedThyroid Cancer | Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) | HRAS Mutant Tumor | Other Squamous Cell Carcinoma (SCC) With HRAS Mutant TumorSpain, United States, Korea, Republic of, France, Belgium, Germany, Greece, Italy, Netherlands, United Kingdom
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Memorial Sloan Kettering Cancer CenterRecruitingStudy of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid CancerThyroid Cancer | Anaplastic Thyroid Cancer | BRAF Gene Mutation | BRAF Mutation-Related TumorsUnited States
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Piramal Enterprises LimitedMelanoma Research Foundation Breakthrough ConsortiumSuspendedAdvanced or Inoperable Malignant Melanoma With BRAF MutationUnited States
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Agenus Inc.CompletedAdvanced Solid Cancers | Advanced Solid Cancers Refractory to PD-1United States
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Asan Medical CenterUnknownCancer | Lung Cancer Metastatic | BRAF V600EKorea, Republic of
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City of Hope Medical CenterNational Cancer Institute (NCI)RecruitingThyroid Gland Anaplastic Carcinoma | BRAF V600K Mutation Present | BRAF NP_004324.2:p.V600EUnited States
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University Health Network, TorontoActive, not recruitingBreast Cancer | Advanced Solid CancersCanada
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STORM Therapeutics LTDRecruitingCancer | Advanced Solid Tumor | Advanced CancerUnited States
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Merck Sharp & Dohme LLCCompletedAdvanced Cancer Relapsed | Advanced Cancer Refractory
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Memorial Sloan Kettering Cancer CenterAstellas Pharma US, Inc.CompletedEGFR-Mutant Lung CancerUnited States
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BiOneCure Therapeutics Inc.RecruitingCancer | Advanced Solid Tumor | Advanced Cancer | OncologyUnited States
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Teon Therapeutics, Inc.Merck Sharp & Dohme LLCTerminatedCancer | Advanced Solid Tumor | Advanced Cancer | OncologyUnited States
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M.D. Anderson Cancer CenterCompletedAdvanced CancersUnited States
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M.D. Anderson Cancer CenterGateway for Cancer Research; Theravalues, Inc.CompletedAdvanced CancersUnited States