Clinical Trials on Advanced Lung Disease

Total 379097 results

University of California, Los Angeles
University of California, San Francisco; University of California, Irvine

Active, not recruiting

UC Health Care Planning Study

Advanced Cancer | Advance Care Planning | Advance Directives

United States
SingHealth Polyclinics

Completed

Increasing the Uptake of Advanced Directives in SingHealth Polyclinics

Advanced Medical Directive, a Legal Document Signed in Advance to State Healthcare Preferences

Singapore
Takeda

Completed

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

Carcinoma, Advanced ALK+ or ROS1+Non-Small-Cell Lung, Neoplasm, Advanced ALK+ or ROS1+Solid Tumors

Spain, Italy, Netherlands, France
Betta Pharmaceuticals Co., Ltd.

Active, not recruiting

The Absorption, Metabolism and Excretion of [14C]D-0316 in Human

Advanced or Metastatic Non-small Cell Lung

China
Ruijin Hospital

Recruiting

Safety and Feasibility of Surgery After Conversion Therapy for Locally Advanced and Advanced NSCLC

Advanced Cancer | Locally Advanced Cancer | Pulmonary Neoplasm

China
Mythic Therapeutics

Recruiting

Clinical Study of Antibody-Drug Conjugate MYTX-011 in Subjects With Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | NSCLC | Advanced Non-Small Cell Lung Cancer | NSCLC Stage IV | NSCLC Stage IIIB | Advanced Non-Small Cell Squamous Lung Cancer | Advanced Non-Small Cell Non-Squamous Lung Cancer

United States, Australia, Korea, Republic of, United Kingdom
Shanghai Fosun Pharmaceutical Industrial Development...

Recruiting

A Phase I/II Clinical Study of SAF-189s in Non-small Cell Lung Cancer (NSCLC) Patients

Advanced Solid Tumor | Advanced Cancer | Lung Cancer, Nonsmall Cell

China
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.

Recruiting

IMM2902 in Patients With Advanced Solid Tumors Expressing HER2

Advanced Solid Tumor | Advanced Gastric Carcinoma | Advanced Cholangiocarcinoma | Advanced Lung Cancer

China
Mersana Therapeutics

Completed

Study of Antibody Drug Conjugate in Patients With Advanced Breast Cancer Expressing HER2

Advanced Breast Cancer | Advanced Gastric Cancer | Advanced Nonsmall Cell Lung Cancer

United States
NeogenTC

Not yet recruiting

TIL Therapy for Patients With Advanced Solid Tumors

Advanced Breast Cancer | Advanced Lung Cancer
University of California, San Francisco

Completed

Treating Frailty in Lung Transplant Candidates (PREHAB) (PREHAB)

Advanced Lung Disease
Arcus Biosciences, Inc.

Recruiting

A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies (ARC-27)

Advanced Cancer

United States
Jiangsu HengRui Medicine Co., Ltd.

Terminated

A Study to Evaluate Camrelizumab Combined With Famitinib as Subsequent Therapy in Patients With Advanced NSCLC

Advanced NSCLC

China
LianBio LLC

Recruiting

Phase I Study of the BBP-398 in Patients With Advance Solid Tumors

Advanced Solid Tumor | Advanced or Metastatic Non-small Cell Lung Cancer

China
Regeneron Pharmaceuticals

Recruiting

Study of REGN5093-M114 (METxMET Antibody-Drug Conjugate) in Adult Patients With Mesenchymal Epithelial Transition Factor (MET) Overexpressing Advanced Cancer

Advanced NSCLC

United States
Mirati Therapeutics Inc.

Terminated

Phase 1/2 Study of Mocetinostat and Durvalumab in Patients With Advanced Solid Tumors and NSCLC

Advanced Cancer

United States
Mayo Clinic

Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Multiple Myeloma | Myelodysplastic Syndrome | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Hematopoietic and Lymphoid System Neoplasm | Advanced Lung Carcinoma | Advanced Prostate Carcinoma | Advanced Glioblastoma | Advanced Gastric Carcinoma | Advanced Breast Carcinoma | Advanced Colorectal... and other conditions

United States
Hatim Husain

Active, not recruiting

Nivolumab and Ipilimumab in Combination With Immunogenic Chemotherapy for Patients With Advanced NSCLC (NSCLC)

Advanced NSCLC

United States
Pfizer

Active, not recruiting

Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies

Non-small-cell Lung Cancer | Advanced Malignancies

China, Korea, Republic of, Taiwan, Japan, Russian Federation, Ukraine
Amgen

No longer available

Expanded Access of Sotorasib

Non Small-cell Lung Cancer | Locally Advanced Unresectable NSCLC | Locally Advanced Metastatic NSCLC

United States, Taiwan, Israel, Saudi Arabia, Brazil, Argentina
Schön Klinik Berchtesgadener Land

Completed

Effect of Inpatient Pulmonary Rehabilitation on Frailty in Candidates for Lung-Transplantation

COPD | ILD | Advanced Lung Disease

Germany
University of Maryland, Baltimore

Active, not recruiting

Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease

Extracorporeal Membrane Oxygenation | Lung Transplant | Advanced Lung Disease

United States
Klaus Kenn

Completed

Effects of Inpatient Pulmonary Rehabilitation on Frailty in Patients After Lung-Transplantation

Interstitial Lung Disease | COPD | Advanced Lung Disease

Germany
AstraZeneca

Completed

Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer

Advanced Non Small Cell Lung Cancer | Advanced (Inoperable) Non Small Cell Lung Cancer

France, Korea, Republic of, United Kingdom, Spain
Bayer

Active, not recruiting

A Study to Learn How Safe the Study Drug BAY 2416964 (AhR Inhibitor) in Combination With the Treatment Pembrolizumab is, How This Combination Affects the Body, the Maximum Amount That Can be Given, How it Moves Into, Through and Out of the Body and Its Action Against Advanced Solid Cancers in Adults

Advanced Solid Tumors

United States, Singapore, Italy, United Kingdom
Bayer

Completed

A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer

Advanced Solid Tumors

Spain, United States, United Kingdom, Germany, Canada
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study to Evaluate the Safety and Tolerability of Using the SHR-1210 by Advanced Solid Tumor Subjects

Advanced Solid Tumors

China
AstraZeneca

Completed

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

Advanced Non Small Cell Lung Cancer | Advanced (Inoperable) Non Small Cell Lung Cancer

Belgium, United States, Korea, Republic of, Taiwan, United Kingdom, Netherlands
AstraZeneca

Completed

AZD9291 First Time In Patients Ascending Dose Study (AURA)

Advanced Non Small Cell Lung Cancer | Advanced (Inoperable) Non Small Cell Lung Cancer

United States, France, Germany, Korea, Republic of, Taiwan, United Kingdom, Spain, Italy, Japan, Australia
Incyte Corporation
Mirati Therapeutics Inc.

Recruiting

A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

Advanced Solid Tumors

United States, Canada, Spain, United Kingdom, Italy
Pfizer

Recruiting

Study of PF-07248144 in Advanced or Metastatic Solid Tumors (KAT6)

Locally Advanced or Metastatic ER+ HER2- Breast Cancer | Locally Advanced or Metastatic Castration-resistant Prostate Cancer | Locally Advanced or Metastatic Non-small Cell Lung Cancer

United States, China, Australia, Korea, Republic of, Japan
Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

A Study of XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors | Locally Advanced or Metastatic Non-small Cell Lung Cancer

China
Dana-Farber Cancer Institute
National Institute on Aging (NIA)

Completed

Advance Care Planning: Communicating With Outpatients for Vital Informed Decision (ACP-COVID)

Covid19 | Advanced Care Planning | Shared Decision Making | Advance Directives | Communication Skills | Video Decision Aids | Natural Language Processing

United States
Dartmouth-Hitchcock Medical Center
Genentech, Inc.; Ligand Pharmaceuticals

Completed

Erlotinib (Tarceva) and Bexarotene (Targretin) Oral Capsules in Advanced Cancers of the Aerodigestive Tract

Advanced, Malignant Aerodigestive Tract Tumor (Lung, Head and Neck and Esophagus)

United States
Novartis Pharmaceuticals

Completed

A Phase I, Multi-center, Open Label, Drug-drug Interaction Study to Assess the Effect of Ceritinib on the Pharmacokinetics of Warfarin and Midazolam in Patients With ALK-positive Advanced Tumors

ALK-positive Advanced Tumors

Italy, Spain, Denmark, United States
AbbVie

Active, not recruiting

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

Advanced Solid Tumors Cancer

United States, Australia, Canada, France, Japan, Korea, Republic of, Spain
Icahn School of Medicine at Mount Sinai
National Institute of Nursing Research (NINR)

Recruiting

Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer (TIER-PC)

Advanced Heart Failure | Advanced Lung Cancer | Advanced Non-colorectal Gastro-intestinal Cancer

United States
AstraZeneca

Completed

A Phase I Study of Safety, Tolerability, and PK of AZD2811 in Patients With Advanced Solid Tumors.

Advanced Solid Tumours

United States
Hunan Province Tumor Hospital

Recruiting

A Real-World Study of Treatment Patterns and Effectiveness in MET Mutation-Positive Advanced Lung Cancer

Advanced Lung Cancer

China
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Study of JS004 Combined With Toripalimab for Advanced Lung Cancer

Advanced Lung Cancer

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Evaluate the Efficacy of IBI939 in Combination With Sintilimab in Patients With Advanced NSCLC

Advanced Lung Cancer

China
Chung Shan Medical University

Completed

Change in NLR and Survival Among Advanced Lung Cancer Patients Receiving ICIs With Immunomodulator

Advanced Lung Cancer

Taiwan
German Cancer Research Center
University Hospital Heidelberg; National Center for Tumor Diseases, Heidelberg

Completed

POSITIVE - Study (Part III) Heidelberg (POSITIVE)

Advanced NSCLC | First Line Treatment

Germany
Second Affiliated Hospital, School of Medicine,...
Westlake Therapeutics

Recruiting

WTX212A Monotherapy and in Combination With PD -1/PD-L1 Monoclonal Antibody

Advanced Lung Cancer

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer

Advanced Lung Carcinoma

China
Fuda Cancer Hospital, Guangzhou
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.

Withdrawn

Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Lung Cancer

Advanced Lung Cancer

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer

Advanced Lung Carcinoma

China
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

JS004 Combined With Toripalimab and With Standard Chemotherapy Treat Patients With Advanced Lung Cancer

Advanced Lung Cancer

China
Mabwell (Shanghai) Bioscience Co., Ltd.

Not yet recruiting

A Phase IIa Study to Evaluate the Efficacy and Safety of 6MW3211 in Patients With Advanced Lung Cancer

Advanced Lung Cancer
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Evaluate the Safety , Tolerability and Efficacy of IBI939 in Combination With Sintilimab in Patients With Advanced Lung Cancer

Advanced Lung Cancer

China

Clinical Trials on Advanced Lung Disease

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