Example: Heart Attack

Clinical Trials on Amyloid Neuropathies, Familial

Total 33 results

NCT03720275

Recruiting

Early and Systematic Screening in Chronic Neuropathy

Conditions: Amyloid Neuropathies, Familial
NCT02191826

Completed

Study of SOM0226 in Familial Amyloid Polyneuropathy

Conditions: Familial Amyloid Polyneuropathy (FAP)
NCT00409175

Completed

Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis

Conditions: Familial Amyloid Polyneuropathy
NCT02175004

Active, not recruiting

Open-Label Extension Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)

Conditions: FAP; Familial Amyloid Polyneuropathy; TTR; Transthyretin; Amyloidosis
NCT01737398

Completed

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Conditions: FAP; Familial Amyloid Polyneuropathy; TTR; Transthyretin; Amyloidosis
NCT03588468

Unknown status

Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological Study

Conditions: Amyloid Neuropathies; Transthyretin Amyloidosis
NCT01435655

Completed

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Conditions: Transthyretin Familial Amyloid Polyneuropathy
NCT04418024

Not yet recruiting

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy

Conditions: Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
NCT03190577

Recruiting

Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology

Conditions: Familial Amyloid Neuropathy; Transthyretin Amyloidosis
NCT00791492

Completed

An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy

Conditions: Familial Amyloid Polyneuropathy; ATTR-PN
NCT00294671

Completed

The Effect of Diflunisal on Familial Amyloidosis

Conditions: Familial Amyloid Polyneuropathy; Familial Amyloidosis
NCT02713880

Completed

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)

Conditions: Transthyretin Amyloidosis; Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy; Transthyretin Amyloid Cardiopathy
NCT02595983

Completed

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

Conditions: Transthyretin (TTR)-Mediated Amyloidosis; Familial Amyloidotic Polyneuropathy (FAP); ATTR Amyloidosis; Familial Amyloid Neuropathies
NCT01960348

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Conditions: TTR-mediated Amyloidosis; Amyloidosis, Hereditary; Amyloid Neuropathies, Familial; Familial Amyloid Polyneuropathies; Amyloid Neuropathies; Amyloidosis, Hereditary, Transthyretin-Related
NCT02939820

Approved for marketing

Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)

Conditions: TTR-mediated Amyloidosis; Amyloidosis, Hereditary; Amyloid Neuropathies, Familial; Familial Amyloid Polyneuropathies; Amyloid Neuropathies; Amyloidosis, Hereditary, Transthyretin-Related
NCT04563286

Recruiting

Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin Amyloidosis

Conditions: Transthyretin Amyloidosis
NCT04306510

Recruiting

A Clinical Study to Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Patients With hATTR-PN

Conditions: Hereditary Transthyretin Amyloidosis With Polyneuropthy
NCT01171859

Completed

Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis

Conditions: Transthyretin Amyloidosis
NCT00628745

Recruiting

Transthyretin-Associated Amyloidosis Outcome Survey (THAOS)

Conditions: Transthyretin Mutations; Transthyretin Amyloidosis
NCT03237494

Recruiting

Epidemiological Analysis for the Hereditary Transthytetin-related Amyloidosis (hATTR)

Conditions: Transthyretin Amyloidosis; Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy; Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy; Polyneuropathies; Cardiomyopathies
NCT02319005

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Conditions: Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC); Amyloidosis, Hereditary; Amyloid Neuropathies, Familial; Amyloid Neuropathies; Amyloidosis, Hereditary, Transthyretin-Related; Familial Transthyretin Cardiac Amyloidosis
NCT04153149

Recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Conditions: Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
NCT03759379

Active, not recruiting

HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

Conditions: Amyloidosis, Hereditary; Transthyretin Amyloidosis
NCT03997383

Recruiting

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Conditions: Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
NCT04601051

Not yet recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN)

Conditions: Hereditary Transthyretin Amyloidosis; Amyloid Neuropathies, Familial; Heredodegenerative Disorders, Nervous System; Neurodegenerative Diseases, Nervous System Diseases; Amyloid Neuropathies; Peripheral Nervous System Diseases; Genetic Diseases, Inborn; Amyloidosis, Familial; Metabolism, Inborn Errors; Proteostasis